Sébastien BROT

Research Engineer at University of Poitiers

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sebastien-brot
0000-0002-4373-2135
IdRef : 168796082

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Présentation

Publications

	Host-to-graft Propagation of α-synuclein in a Mouse Model of Parkinson’s Disease: Intranigral Versus Intrastriatal Transplantation Maëlig Patrigeon , Sébastien Brot , Marie-Laure Bonnet , Laure Belnoue , Afsaneh Gaillard Transplantation, 2023, Publish Ahead of Print, ⟨10.1097/TP.0000000000004565⟩ Article dans une revue hal-04132835v1
	Deciphering Brain Metastasis Stem Cell Properties From Colorectal Cancer Highlights Specific Stemness Signature and Shared Molecular Features Amandine Desette , Pierre-Olivier Guichet , Sheik Emambux , Konstantin Masliantsev , Ulrich Cortes Cellular and Molecular Gastroenterology and Hepatology, 2023, 16 (5), pp.757-782. ⟨10.1016/j.jcmgh.2023.07.008⟩ Article dans une revue hal-04302791v1
	Beneficial Effects of Hyaluronan-Based Hydrogel Implantation after Cortical Traumatic Injury Anaïs Lainé , Sébastien Brot , Afsaneh Gaillard Cells, 2022, 11 (23), pp.3831. ⟨10.3390/cells11233831⟩ Article dans une revue hal-04132825v1
	Better Outcomes with Intranigral versus Intrastriatal Cell Transplantation: Relevance for Parkinson’s Disease Marine Droguerre , Sébastien Brot , Clément Vitrac , Marianne Benoit-Marand , Laure Belnoue Cells, 2022, 11 (7), ⟨10.3390/cells11071191⟩ Article dans une revue hal-03637153v1
	Long-Term Evaluation of Intranigral Transplantation of Human iPSC-Derived Dopamine Neurons in a Parkinson’s Disease Mouse Model Sébastien Brot , Nabila Pyrenina Thamrin , Marie-Laure Bonnet , Maureen Francheteau , Maëlig Patrigeon Cells, 2022, 11 (10), pp.1596. ⟨10.3390/cells11101596⟩ Article dans une revue hal-03682097v1
	Neuroprotective effects of neuropeptide Y against neurodegenerative disease Stéphanie Pain , Sébastien Brot , Afsaneh Gaillard Current Neuropharmacology, 2021, 19, ⟨10.2174/1570159X19666210906120302⟩ Article dans une revue hal-03361423v1
	Characterization of Inflammation in Delayed Cortical Transplantation Nissrine Ballout , Tristan Rochelle , Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau Frontiers in Molecular Neuroscience, 2019, 12, ⟨10.3389/fnmol.2019.00160⟩ Article dans une revue hal-02498268v1
	A Delay between Motor Cortex Lesions and Neuronal Transplantation Enhances Graft Integration and Improves Repair and Recovery Sophie Péron , Marine Droguerre , Franck Debarbieux , Nissrine Ballout , Marianne Benoit-Marand Journal of Neuroscience, 2017, 37 (7), pp.1820-1834. ⟨10.1523/JNEUROSCI.2936-16.2017⟩ Article dans une revue hal-02500429v1
	Collapsin response-mediator protein 5 (CRMP5) phosphorylation at threonine 516 regulates neurite outgrowth inhibition Sébastien Brot , Hinda Smaoune , Mina Youssef-Issa , Céline Malleval , Claire Benetollo European Journal of Neuroscience, 2014, 40 (7), pp.3010-3020. ⟨10.1111/ejn.12674⟩ Article dans une revue hal-02511291v1
	Collapsin Response Mediator Protein 5 (CRMP5) Induces Mitophagy Thereby Regulating Mitochondrion Numbers in Dendrites. Sébastien Brot , Carole Auger , Rabia Bentata , Véronique Rogemond , Stéphane Ménigoz Journal of Biological Chemistry, 2013, 289, pp.2261-2276. ⟨10.1074/jbc.M113.490862⟩ Article dans une revue hal-00917349v1
	Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA. Dominique Bétemps , Jérémy Verchère , Sébastien Brot , Eric Morignat , Luc Bousset Acta Neuropathologica Communications, 2013, 2, pp.29. ⟨10.1186/2051-5960-2-29⟩ Article dans une revue hal-01183383v1
	Identification of a new CRMP5 isoform present in the nucleus of cancer cells and enhancing their proliferation Sébastien Brot , Céline Malleval , Claire Benetollo , Carole Auger , David Meyronet Experimental Cell Research, 2013, 319 (5), pp.588-599. ⟨10.1016/j.yexcr.2012.12.011⟩ Article dans une revue hal-02511307v1
	CRMP5 Interacts with Tubulin to Inhibit Neurite Outgrowth, Thereby Modulating the Function of CRMP2 Sébastien Brot , Véronique Rogemond , Valérie Perrot , Naura Chounlamountri , Carole Auger Journal of Neuroscience, 2010, 30 (32), pp.10639-10654. ⟨10.1523/JNEUROSCI.0059-10.2010⟩ Article dans une revue hal-02351827v1

	Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot PHysiopathology Of Parkinson’s disEase » (HOPE), Jan 2020, Paris, France Communication dans un congrès hal-02511362v1
	La reprogrammation d’hiPSC par ARNm, une nouvelle approche pour la transplantation de neurones dopaminergiques Sébastien Brot Journée scientifique SFR FED 4226 Neuroimagerie Fonctionnelle, Jun 2017, Poitiers, France Communication dans un congrès hal-02511347v1

	Functional integration of intranigral grafted hiPSC derived dopamine neurons in a mouse model of Parkinson disease Bérangère Ballion , Sébastien Brot , Laure Belnoue , Afsaneh Gaillard FENS Forum 2022, Jul 2022, Paris, France. Poster de conférence hal-04517426v1
	Modelling Parkinson´s disease with patient induced pluripotent stem cells Nabila Pyrenina Thamrin , Marie-Laure Bonnet , Maëlig Patrigeon , Laure Belnoue , Jean Christophe C Corvol NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03221486v1
	Functional integration of grafted hiPSC derived dopamine neurons in a murine model of Parkinson's disease Bérangère Ballion , Laure Belnoue , Sébastien Brot , Afsaneh Gaillard NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03405614v1
	Host to graft propagation of α-synuclein in Parkinson’s disease: intra-nigral versus intra-striatal transplantation. Maëlig Patrigeon , Sébastien Brot , Marie-Laure Bonnet , Laure Belnoue , Afsaneh Gaillard NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03221475v1
	The potential of motor cortical neurons derived hiPSC transplantation for brain repair following traumatic brain injury Laure Belnoue , Hammam I. El Hajj , Marie-Laure Bonnet , Sébastien Brot , Afsaneh Gaillard NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03221118v1
	Biomaterials to enhance the integration of grafted human iPSC-derived motor cortical neurons in a mice model of traumatic injury Oriane Rabesandratana , Anaïs Lainé , Marie-Laure Bonnet , Laure Belnoue , Sébastien Brot FSSCR annual meeting 2021, Nov 2021, Montpellier, France Poster de conférence hal-03489108v1
	Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot , Marie-Laure Bonnet , Maëlig Patrigeon , Maureen Francheteau , Laure Belnoue NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03221124v1
	Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot , Marie-Laure Bonnet , Bérangère Ballion , Maëlig Patrigeon , Maureen Francheteau 31st Annual meeting of the Network for European CNS Transplantation and Restoration (NECTAR), Nov 2021, Edinburgh, France. Poster de conférence hal-03637185v1
	Therapeutic effects of hyaluronan-based hydrogel after cortical traumatic injury Anaïs Lainé , Sébastien Brot , Oriane Rabesandratana , Afsaneh Gaillard NeuroFrance 2021, May 2021, Strasbourg, France Poster de conférence hal-03221468v1
	Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Laure Belnoue , Afsaneh Gaillard PHysiopathology Of Parkinson’s disEase » (HOPE), Jan 2020, Paris, France Poster de conférence hal-02511393v1
	Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard FSSCR 3rd Annual Meeting, Nov 2019, Lyon, France Poster de conférence hal-02512692v1
	The potential of motor cortical neurons derived hiPSC transplantation for brain repair following traumatic brain injury Hammam L El Hajj , Laure Belnoue , Marie-Laure Bonnet , Sébastien Brot , Afsaneh Gaillard Neurofrance, Jun 2019, Marseille, France Poster de conférence hal-02516060v1
	Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard From 3D culture to organoïds - AVIESAN, Dec 2019, Paris, France Poster de conférence hal-02512008v1
	Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard LE STUDIUM CONFERENCE : Induced Pluripotent Stem Cells (iPSCs): From Disease Models to Mini-Organs, Jan 2019, Tours, France Poster de conférence hal-02512709v1
	Absence of interleukin 33 impaired axonal outgrowth of grafted cortical neurons. Anaïs Lainé , Nissrine Ballout , Marie Droguerre , Sébastien Brot , Maureen Francheteau NeuroFrance, the international conference of the french society of Neuroscience, May 2019, Marseille, France Poster de conférence hal-02547007v1
	Differentiation of human iPSC into neurons of motor cortex and grafting into injured motor cortex of adult mice Hammam L El Hajj , Sébastien Brot , Marie-Laure Bonnet , Afsaneh Gaillard 11th FENS forum of Neurosciences, Jul 2018, Berlin, Germany Poster de conférence hal-02516097v1
	Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard 11th FENS Forum of Neuroscience, Jul 2018, Berlin, Germany Poster de conférence hal-02512713v1
	Dopamine neurons derived from human induced pluripotent stem cell reprogrammed by mRNA Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard Neurofrane, May 2017, Bordeaux, France Poster de conférence hal-02516038v1
	Beneficial effects of inflammation in delayed cortical transplantation Nissrine Ballout , Tristan Rochelle , Sébastien Brot , Maureen Francheteau , Jean-Marc Gombert Neurofrance, May 2017, Bordeaux, France Poster de conférence hal-02517467v1
	Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease Sébastien Brot , Marie-Laure Bonnet , Maureen Francheteau , Afsaneh Gaillard Symposium "(Re)Constructing the nervous system: stem cells and beyond" Institut fer à Moulin, Sep 2017, Paris, France Poster de conférence hal-02516028v1
	Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells Sandie Brisson , Bhaskar Saha , Tristan Rochelle , Sébastien Brot , Marie-Laure Bonnet Plasticité cérébrale, de la recherche fondamentale à la clinique - 2e Journées Thématiques de la société des neurosciences, May 2016, Tours, France Poster de conférence hal-02517846v1
	Study of Neuroinflammation after cortical lesion and transplantation with or without delay Nissrine Ballout , Tristan Rochelle , Sébastien Brot , Maureen Francheteau , Jean-Marc Gombert Plasticité cérébrale, de la recherche fondamentale à la clinique 2e Journées Thématiques de la société des Neurosciences, May 2016, Tours, France Poster de conférence hal-02517855v1
	Molecular and cellular alterations underlying motor disorders in autism spectrum disorders mouse models Obélia Haida , Tareq Al Sagheer , Anais Balbous , Sébastien Brot , Maureen Francheteau Séminaire thématique bio-santé ED 524, Mar 2016, Pouligny-Notre-Dame, France Poster de conférence hal-02556995v1
	Study of Neuroinflammation after cortical lesion and transplantation with or without delay Nissrine Ballout , Tristan Rochelle , Sébastien Brot , Maureen Francheteau , Jean-Marc Gombert 12e colloque de la société des Neurosciences, May 2015, Montpellier, France Poster de conférence hal-02517504v1
	Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells Sébastien Brot , Sandie Brisson , Bhaskar Saha , Tristan Rochelle , Marie-Laure Bonnet 3ème Journée Scientifique de la SFR Tours-Poitiers, Jun 2015, Tours, France Poster de conférence hal-02517803v1
	Nigrostriatal pathway reconstruction by transplanting embryonic stem cell-derived dopaminergic neurons in Parkinson’s disease Tristan Rochelle , Sandie Brisson , Sébastien Brot , Marie-Laure Bonnet , Marine Droguerre 2ème Journée Scientifique de la SFR Tours-Poitiers, Jun 2014, Poitiers, France Poster de conférence hal-02517734v1
	Delaying cortical transplantation improves the outcome of the graft Afsaneh Gaillard , Sophie Péron , Marine Droguerre , Nissrine Ballout , Sébastien Brot 9th FENS Forum of Neuroscience, Jul 2014, Milan, Italy Poster de conférence hal-02517797v1
	Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells Sandie Brisson , Bhaskar Saha , Tristan Rochelle , Sébastien Brot , Marie-Laure Bonnet Journée de recherche Tours-Poitiers-Limoges, Jan 2014, Tours, France Poster de conférence hal-02517712v1
	Differential localization of CRMP5 in cancer cells compared to normal condition Sébastien Brot , Claire Benetollo , Celine Malleval , Jérome Honnorat 5ème journée scientifique du CLARA "Cancéropôle Lyon Auvergne Rhône-Alpes", Mar 2010, Lyon, France Poster de conférence hal-02518843v1
	Collapsin Response Mediator Protein 5, a multifunction protein involved in neuronal polarity and mitochondrial machinery Sébastien Brot , Carole Auger , Véronique Rogemond , Jérome Honnorat , Mahnaz Moradi-Améli 7th FENS Forum of European Neuroscience, Jul 2010, Amsterdam, Netherlands Poster de conférence hal-02518829v1
	Identification of a direct interaction between CRMP5 and tubulin involved in neurite outgrowth inhibition Sébastien Brot , Véronique Rogemond , Valérie Perrot , Naura Chounlamountri , Carole Auger 9ème Colloque de la société des Neurosciences, May 2009, Bordeaux, France Poster de conférence hal-02518885v1
	Study of CRMP5 properties and its role in the development of cerebral tumors Sébastien Brot , Celine Malleval , Jérome Honnorat , Mahnaz Moradi-Améli 3ème journée scientifique du CLARA "Cancéropôle Lyon Auvergne Rhône-Alpes", Mar 2008, Lyon, France Poster de conférence hal-02518895v1

Sébastien BROT

Présentation

Publications

Host-to-graft Propagation of α-synuclein in a Mouse Model of Parkinson’s Disease: Intranigral Versus Intrastriatal Transplantation

Deciphering Brain Metastasis Stem Cell Properties From Colorectal Cancer Highlights Specific Stemness Signature and Shared Molecular Features

Beneficial Effects of Hyaluronan-Based Hydrogel Implantation after Cortical Traumatic Injury

Better Outcomes with Intranigral versus Intrastriatal Cell Transplantation: Relevance for Parkinson’s Disease

Long-Term Evaluation of Intranigral Transplantation of Human iPSC-Derived Dopamine Neurons in a Parkinson’s Disease Mouse Model

Neuroprotective effects of neuropeptide Y against neurodegenerative disease

Characterization of Inflammation in Delayed Cortical Transplantation

A Delay between Motor Cortex Lesions and Neuronal Transplantation Enhances Graft Integration and Improves Repair and Recovery

Collapsin response-mediator protein 5 (CRMP5) phosphorylation at threonine 516 regulates neurite outgrowth inhibition

Collapsin Response Mediator Protein 5 (CRMP5) Induces Mitophagy Thereby Regulating Mitochondrion Numbers in Dendrites.

Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA.

Identification of a new CRMP5 isoform present in the nucleus of cancer cells and enhancing their proliferation

CRMP5 Interacts with Tubulin to Inhibit Neurite Outgrowth, Thereby Modulating the Function of CRMP2

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

La reprogrammation d’hiPSC par ARNm, une nouvelle approche pour la transplantation de neurones dopaminergiques

Functional integration of intranigral grafted hiPSC derived dopamine neurons in a mouse model of Parkinson disease

Modelling Parkinson´s disease with patient induced pluripotent stem cells

Functional integration of grafted hiPSC derived dopamine neurons in a murine model of Parkinson's disease

Host to graft propagation of α-synuclein in Parkinson’s disease: intra-nigral versus intra-striatal transplantation.

The potential of motor cortical neurons derived hiPSC transplantation for brain repair following traumatic brain injury

Biomaterials to enhance the integration of grafted human iPSC-derived motor cortical neurons in a mice model of traumatic injury

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Therapeutic effects of hyaluronan-based hydrogel after cortical traumatic injury

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

The potential of motor cortical neurons derived hiPSC transplantation for brain repair following traumatic brain injury

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Absence of interleukin 33 impaired axonal outgrowth of grafted cortical neurons.

Differentiation of human iPSC into neurons of motor cortex and grafting into injured motor cortex of adult mice

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Dopamine neurons derived from human induced pluripotent stem cell reprogrammed by mRNA

Beneficial effects of inflammation in delayed cortical transplantation

Potential of dopamine neurons derived from human induced pluripotent stem cells reprogrammed by mRNA for Parkinson’s disease

Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells

Study of Neuroinflammation after cortical lesion and transplantation with or without delay

Molecular and cellular alterations underlying motor disorders in autism spectrum disorders mouse models

Study of Neuroinflammation after cortical lesion and transplantation with or without delay

Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells

Nigrostriatal pathway reconstruction by transplanting embryonic stem cell-derived dopaminergic neurons in Parkinson’s disease

Delaying cortical transplantation improves the outcome of the graft

Production and characterization of dopaminergic neurons derived from mouse embryonic stem cells

Differential localization of CRMP5 in cancer cells compared to normal condition

Collapsin Response Mediator Protein 5, a multifunction protein involved in neuronal polarity and mitochondrial machinery

Identification of a direct interaction between CRMP5 and tubulin involved in neurite outgrowth inhibition

Study of CRMP5 properties and its role in the development of cerebral tumors