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Pascale Chavatte-Palmer
Pascale Chavatte-Palmer, INRAE
Director of the BREED Research unit, University Paris-Saclay, INRAE, University Versailles Saint-Quentin, Ecole nationale Vétérinaire d'Alfort
France
34%
Libre accès
35
Documents
Affiliations actuelles
- 1003282
Identifiants chercheurs
- pascale-chavatte-palmer
- ResearcherId : K-7349-2012
- 0000-0002-4581-6092
- IdRef : 153497998
- ResearcherId : http://www.researcherid.com/rid/K-7349-2012
Présentation
**Directrice de l'unité Mixte de Recherches Biologie de la Reproduction, Environnement, Epigénétique et Développement**
Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France
Ecole Nationale Vétérinaire d’Alfort, BREED, 94700, Maisons-Alfort, France
Initially trained as a veterinarian, I specialized in animal, and particularly equine reproduction with a focus on pregnancy and neonatology through my internship, residency and PhD, post-doctoral fellowship and initial position. After my recruitment at AgroParisTech and subsequently INRAE in France, I have been more widely focusing on feto-placental development and the developmental origins of health and disease (DOHaD), with a dual purpose in agriculture and as biomedical models. The aim of my research is to understand the role of the placenta in the programming of long term post-natal health, in the context of the developmental origins of health and diseases. First as a veterinarian and subsequently to be able to perform longitudinal studies in research animals, I have also been developing in vivo imaging technologies such as ultrasound and Doppler to assess placental feto-placental development and placental perfusion. After having led a research group at the National Institute of Agronomical Research (now INRAE), with a mean of 12 permanent staff for the past 14 years, I have recently taken the lead of the new Biology of Reproduction, Environment, Epigenetics and Development (BREED) research unit (90 permanent staff), focusing on the development of the mammalian embryo from the formation of the egg cell to birth and development to adulthood. Projects range from fundamental studies on the functioning of the genome during embryo and fetal growth to applied research on the effects of the environment at large on development in the agronomic, veterinary and biomedical fields. The scientific objective is to understand and control the mechanisms of epigenetic programming during prenatal life, leading to the birth of a healthy, fertile and robust individual, able to adapt to changes in his environment. Meanwhile, I pursue my own research programs on effects of maternal and post-natal breeding conditions, including nutrition, on metabolic and osteoarticular outcomes in the foal. I have served as PI or co-PIU to several national and European research projects (see section D).
Publications
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Obesity during pregnancy in the horse: effect on term placental structure and gene expression, as well as colostrum and milk fatty acid concentrationsXIIth International equine reproduction symposium (ISER), ISER, Jul 2023, Fos of Iguaçu, Brazil. pp.104801, ⟨10.1016/j.jevs.2023.104801⟩
Communication dans un congrès
hal-04147617v1
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Effets de la supplémentation alimentaire en arginine chez les juments gravides sur le métabolisme maternal, la fonction placentaire et le poids de naissance des poulains4. Congrès de la SF-Dohad, Société Francophone de la Dohad., Nov 2018, Grenoble, France. pp.120
Communication dans un congrès
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Placental function at term is altered in broodmares fed with cereals from mid gestationIETS, International Embryo Transfer Society (IETS). USA., Jan 2018, Bangkok, Thailand. pp.250, ⟨10.1071/RDv30n1Ab65⟩
Communication dans un congrès
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Importance potentielle de la programmation métabolique dans la filière équineJournées d'Animation Scientifique du Département PHASE- INRA, Apr 2018, Rennes, France
Communication dans un congrès
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Caractérisation ultra structurale du placenta équin après supplémentation alimentaire en arginine des juments au dernier tiers de la gestation17.Journées de formation du RCCM (Réseau des Centres Communs de Microscopie), Centre National de la Recherche Scientifique (CNRS). FRA., Jun 2018, Clermont-Ferrand, France
Communication dans un congrès
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Influence de l'obésité maternelle dès la conception sur la santé métabolique et ostéoarticulaire dans un modèle cheval22. Journées de la Fédération Française d'Etude de la Reproduction, Fédération Française d'Etude de la Reproduction (FFER). FRA., Sep 2017, Tours, France
Communication dans un congrès
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The developmental origins of health and disease: importance for animal production29. Annual Meeting of the Brazilian Embryo Technology Society (SBTE), Brazilian Embryo Technology Society (SBTE). BRA., Aug 2015, Gramado, Brazil
Communication dans un congrès
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Barley supplementation at mid-gestation in broodmares does not affect fetal development and is accompanied by minimal placental adaptations41. Annual Conference of IETS, International Embryo Transfer Society (IETS). USA., Jan 2015, Versailles, France. ⟨10.1071/RDv27n1Ab110⟩
Communication dans un congrès
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La santé du futur poulain se prépare dès la gestation41. Journée de la Recherche Equine, Institut Français du Cheval et de l'Equitation (IFCE). FRA., Mar 2015, Paris, France
Communication dans un congrès
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Developmental programming of growth, glucose homeostasis and predisposition to osteochondrosis in foalsEquine Reproduction Symposium, Académie d'Agriculture de France (AAF). FRA., Jan 2015, Paris, France. 55 p
Communication dans un congrès
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The development origins of health and disease: Importance for animal production31ème colloque scientifique AETE, Association Européenne de Transfert Embryonnaire - European Embryo Transfer Association (AETE). FRA., Sep 2015, Ghent, Belgium
Communication dans un congrès
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Periconceptional body condition induces placental adaptations but does not affect foal growth and metabolism in horses31. Colloque Scientifique de l'AETE, Association Européenne de Transfert Embryonnaire - European Embryo Transfer Association (AETE). FRA., Sep 2015, Ghent, Belgium
Communication dans un congrès
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The placenta: a key actor in programming adult phenotypeAustralasian Equine Science Symposium, Australasian Equine Science. AUS., Jul 2014, Gold Coast, Australia. 71 p
Communication dans un congrès
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Feeding pregnant mares with concentrates has no impact on pre-weaning foals growth and glucose metabolismAustralasian Equine Science Symposium, Australasian Equine Science. AUS., Jul 2014, Gold Coast, Australia. 71 p
Communication dans un congrès
hal-02740876v1
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Effets de la supplémentation alimentaire en arginine chez les juments gravides sur le métabolisme maternel, la fonction placentaire et le poids de naissance des poulains.7. Rencontre du Groupe de la Francophonie Placentaire 2019, Mar 2019, Paris, France. 36p, 2019
Poster de conférence
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Effects of dietary arginine supplementation to primiparous mares in the last third of gestation on foal birthweight and placental functionIFPA 2018, Sep 2018, Tokyo, France. , Placenta, 69, pp.93, 2018, Abstracts for the forthcoming International Federation of Placenta Associations Meeting, Tokyo, Japan September 21 - 24, 2018
Poster de conférence
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Effects of maternal obesity during pregnancy on foals’ growth, carbohydrate metabolism, systemic inflammation and osteochondrosis until one year of age8. European Equine Health & Nutrition Congress, Mar 2017, Antwerp, Belgium. , 137 p., 2017, 8th EEHNC: From nutrition to disease and back
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La supplémentation en céréales en fin de gestation perturbe la fonction placentaire chez la jument6. Colloque International du Groupe de la Francophonie Placentaire, Sep 2017, Grenoble, France. , 47 p., 2017, Sixième Colloque International du Groupe de la Francophonie Placentaire "De l'implantation à la parturition: Bases fondamentales et cliniques"
Poster de conférence
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Maternal obesity at conception and insulin sensitivity in late gestation alters placental structure but not fetal biometry at birth in the horse43. Annual Conference of the International Embryo Technology Society, Jan 2017, Austin, Texas, United States. CSIRO Publishing, Reproduction, Fertility and Development, 29, 222 p., 2017, Reproduction, Fertility and Development. ⟨10.1071/RDv29n1Ab67⟩
Poster de conférence
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The mare’s placenta is able to adapt to moderate maternal undernutrition during late gestation to sustain fetal growth18. International Congress on Animal Reproduction (ICAR), Jun 2016, Tours, France. , 676 p., 2016, 18th International Congress on Animal Reproduction (ICAR)
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Maternal nutrition during pregnancy affects testicular and bone development, glucose metabolism and response to overnutrition in weaned horses up to two yearsPoster de conférence hal-02741242v1 |
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Periconceptional body condition, feto-placental development and foal metabolism in horsesEpiconcept Conference 2015 - Epigenetics and Periconception Environnement, Oct 2015, Hersonissos, Greece. Cost Office, 2015, Conférence 2015 " Epigenetics and periconception environment"
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Effects of maternal nutrition in late-pregnancy on placental structure and function and the neonatal foal’s response to glucose7. European Equine Health & Nutrition Congress, Mar 2015, Bruges, Belgium. , 146 p., 2015, European Equine Health & Nutrition Congress 7th Edition
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Intrauterine growth enhancement and restriction are associated with alterations in term placenta morphology, morphometry and function in horsesMeeting of the International Federation of Placenta Associations (IFPA), Sep 2014, Paris, France. Elsevier, Placenta, 35 (9), 2014, IFPA Meeting. ⟨10.1016/j.placenta.2014.06.083⟩
Poster de conférence
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Barley supplementation at mid-gestation in broodmares does not affect fetal development and is accompanied with minimal placental adaptations2. Colloque de la SF-DOHaD, Origine Développementale de la santé et des maladies et épigénétique, Nov 2014, Nantes, France. , 57 p., 2014, SeconD Colloque SF-DOHaD 2014
Poster de conférence
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