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Marc Boudvillain

7
Documents
Identifiants chercheurs

Présentation

- **CNRS Research director** and group Leader at CBM - **Deputy director** of CBM since January 2018. Education --------- - **PhD Thesis** in Biochemistry and Molecular Biophysics, University of Orléans (1996). - **Master of Science** (specialty: Biological Chemistry) from the Universities of Orléans, Paris Descartes, and Paris Sud (joint program, 1992). Professional experience ----------------------- - **Tenured Scientist** at CNRS, CBM since October 1999. Biochemistry of RNA and RNA-protein complexes; Regulation of bacterial transcription; RNA helicase mechanisms - **Postdoctoral Research Scientist** at Columbia University and Howard Hugues Medical Institute (New York, USA). Biochemistry of RNA; Structure, function and catalysis by group II intron ribozymes (1996-1999). - **Graduate Research Scientist** at CBM. Nucleic acid Biochemistry; Inorganic chemistry; Engineering of synthetic Pt(II)-based metalloribozymes (1993-1996).

Publications

rozenn-dalbies-tran

Oligonucleotides Modified With Transplatin Derivatives: Fast and Efficient Metalloribozymes

 Boudvillain Marc , Rozenn Dalbies-Tran , Marc Leng , Marc Boudvillain
Metal-Based Drugs, 2001, 8 (1), pp.39 - 45. ⟨10.1155/MBD.2001.39⟩
Article dans une revue hal-01880601v1

Transplatin-Modified Oligo(2‘- O -methyl ribonucleotide)s: A New Tool for Selective Modulation of Gene Expression †

 Marc Boudvillain , Martine Guerin , Rozenn Dalbies , Tula Saison-Behmoaras , Marc Leng
Biochemistry, 1997, 36 (10), pp.2925 - 2931. ⟨10.1021/bi962695f⟩
Article dans une revue hal-01880625v1

Evidences for a catalytic activity of the DNA double helix in the reaction between DNA, platinum(II), and intercalators.

 Marc Boudvillain , Rozenn Dalbies , M. Leng
Metal Ions in Biological Systems, 1996, 33, pp.87-104
Article dans une revue hal-02322086v1

Linkage isomerization reaction of intrastrand cross-links in trans -diamminedichloroplatinum(II)-modified single-stranded oligonucleotides

 Rozenn Dalbies , Marc Boudvillain , Marc Leng
Nucleic Acids Research, 1995, 23 (6), pp.949-953. ⟨10.1093/nar/23.6.949⟩
Article dans une revue hal-02075321v1

Intrastrand cross-links are not formed in the reaction between transplatin and native DNA: relation with the clinical inefficency of transplatin

 Marc Boudvillain , Rozenn Dalbies , Christophe Aussourd , Marc Leng
Nucleic Acids Research, 1995, 23 (13), pp.2381-2388. ⟨10.1093/nar/23.13.2381⟩
Article dans une revue hal-02075318v1

Trans-Diamminedichloroplatinum (II) Is Not an Antitumor Drug: Why?

 Marc Boudvillain , Rozenn Dalbies-Tran , Leng M.
Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, 2, Plenum Press, New'Tork, USA, pp.17-25, 1996
Chapitre d'ouvrage hal-02097755v1

Procédé de pontage sélectif et irréversible d'oligonucléotides platinés sur de l'ARN et ses applications

 Marc Leng , Rozenn Dalbies , Marc Boudvillain
France, Patent n° : WO1998018915A2. 1996
Brevet hal-02097839v1