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Fabrice BESNARD

Chercheur INRAE (CRCN)
63%
Libre accès
8
Documents
Affiliations actuelles
  • 577435
  • 1001887
Identifiants chercheurs
Contact
Site web
  • https://www.ens-lyon.fr/RDP/signalisation-hormonale-et-developpement/

Présentation

###### **Researcher (CRCN) INRAE** Date of Birth: 2/04/1983 I am working in the lab "[Plant Reproduction and Development](https://www.ens-lyon.fr/RDP/)" in the team "[Hormonal signals](https://www.ens-lyon.fr/RDP/signalisation-hormonale-et-developpement/?lang=en)". I am a plant developmental biologist interested in how the **robustness of morphogenesis and cell differentiation** is controlled across different scales during development and growth. My main working system is the **shoot apical meristem** of the model plant *Arabidopsis thaliana*, which is responsible for the generation of all above-ground part of the plant: leaves, stems, branches, flowers, fruits... My favorite developmental processes are **phyllotaxis** (the geometrical arragement of leaves and fruits around shoots) and **early organogenesis** from stem cells to produce flower or leaf (bract). I am using and developping **quantitative approaches** in genetics, genomics, confocal-microscope live imaging or macroscopic phenotyping to characterize the different factors that canalize development into reproducible shapes and patterns or, conversely, explain the origin of consistent phenotypic variations. Among these different factors, I give a particular focus on **hormonal signalling** (auxin, cytokinin, gibberellins) which are known important inter-cellular signals and is a strong expertise in my team. I am also using **forward genetics** to discover new genetic regulator without *a priori*, especially among natural genetic variations, which provides real examples of the evolution of genetic robustness in **natural populations**. I also work in strong colaboration with computer scientists, mathematicians and modelers to **develop quantitative tools, data and image analysis pipelines or modeling frameworks**. ###### **ADDRESS** Laboratoire REPRODUCTION ET DÉVELOPPEMENT DES PLANTES ENS de Lyon 46, allée d'Italie, 69364 LYON Cedex 07 FRANCE fabrice.besnard@ens-lyon.fr ###### **EDUCATION** * 2011: PhD in plant developmental biology (ENS de Lyon, France). * 2008: Master2 in cell and molecular Biology, speciality in developmental biology (Université PMC, Paris VI, France) * 2006: Agrégation des SV-STU (secondary school teacher exam, training peformed at Paris Sud-Orsay-XI & ENS Paris, France) * 2003-2005: Undergraduate studies (ENS Paris & Université PMC-Paris VI, France) * 2001-2003: Undergraduate studies (Lycée Chateaubriand, Rennes, France) ###### **POSITIONS** * 2022: Member of the CN section 23 CNRS Biologie * 2016: Recruited Scientist INRA (CRCN INRA), 2016. * 2012-2016: Postdoctoral researcher, ENS, Paris, France,

Domaines de recherche

Biologie du développement Morphogenèse Bio-Informatique, Biologie Systémique [q-bio.QM] Génétique des plantes

Publications

"christophe-godin"
Image document

Hierarchical Developmental Timeline Warping: a generic method to design realistic plant architecture models

Christophe Godin , Fabrice Besnard
10th conference on Structural-Functional Plant Models, Mar 2023, Berlin (DE), France
Communication dans un congrès hal-04392528v1
Image document

A Combinatorial Model of Phyllotaxis Perturbations in Arabidopsis thaliana

Yassin Refahi , Etienne Farcot , Yann Guédon , Fabrice Besnard , Teva Vernoux
22nd Annual Symposium on Combinatorial Pattern Matching, Palermo, Italy, 2011, Palermo, Italy. pp.323--335
Communication dans un congrès hal-00828852v1

A combinatorial model of phyllotaxis perturbations in [i]Arabidopsis thaliana[/i]

Yassin Refahi , Etienne Farcot , Yann Guédon , Fabrice Besnard , Teva Vernoux
22. Annual Symposium on Combinatorial Pattern Matching (CPM 2011), Jun 2011, Palerme, Italy. 480 p
Communication dans un congrès hal-01190615v1
Image document

Analyzing perturbations in phyllotaxis of Arabidopsis thaliana

Yassin Refahi , Yann Guédon , Fabrice Besnard , Etienne Farcot , Christophe Godin
6th International Workshop on Functional-Structural Plant Models, 2010, Davis, CA, United States. pp.185-187
Communication dans un congrès hal-00831773v1