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Christine Leroux
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Documents
Identifiants chercheurs
- christine-leroux
- 0000-0001-6835-3978
- Google Scholar : https://scholar.google.com/citations?user=FdeOzCAAAAAJ&hl=fr
- IdRef : 193885018
Présentation
Christine Leroux (women, PhD, HDR) is a research director from INRAE, the French national institute for research in agriculture, nutrition and environment. After obtaining her PhD in Molecular Genetics (University of Orsay-Paris XI, France) in 1992, Christine started to work at INRA on milk components biosynthesis and secretion in dairy ruminants. She studies the effects of different factors (mainly genetics and nutritional) influencing mammary gland functioning during lactation. Christine’s research aims to improve nutritional quality of milk for consumers and to identify indicators of animal metabolism and health using strategies of nutrigenomics. She firstly studied the effects of genetics polymorphism on protein synthesis, and then she worked on effects of ruminant nutrition on mammary and in a lesser extent on adipose tissues gene expression associated with milk fat composition. More recently, she initiated studies on microRNA and their nutritional regulation in mammary gland. She was visiting researcher scientist at University of California Davis (2017-2019) where she investigated the potential role of milk microRNA as a food source bioactive and contributor to human health. End of 2020, she had 5383 citations and an h-index of 41 referenced by Google Scholar. She participated to 15 national and international research projects. She has 8 years of experience of management of research groups (more than 15 persons) and of a transcriptomic platform, and she has supervised over 26 students (both undergraduates and graduates).
Publications
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La composition en microARN du lait sous influence des races bovinesJournées Scientifiques du Département Génétique Animale (JSGA), Département Génétique Animale, INRAE, Sep 2022, Bordeaux, France
Communication dans un congrès
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Les exosomes : des véhicules de signatures moléculaires pour comprendre le dialogue entre les organes des ruminants1. Rencontres Clermontoises sur les Vésicules Extracellulaires, Laurent-Emmanuel MONFOULET-INRAE-UNH (Organisateur), Feb 2022, Clermont-Ferrand, France. ⟨10.17180/ev22-co02⟩
Communication dans un congrès
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Les métabolites et les acides gras du lait : des indicateurs non invasifs du statut métabolique et du bilan énergétique chez les vaches laitièresRésumés - Réunion virtuelle Glande mammaire lait / Galactinnov, INRAE, Animation transversale Phase Galactinov, Nov 2021, en ligne, France
Communication dans un congrès
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Impact d’une restriction alimentaire sur les miRNome et protéome du lait chez la vache laitièreGlande mammaire lait / Galactinnov, Nov 2021, En ligne, France
Communication dans un congrès
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Feed restriction affects protein and microRNA levels in dairy cows' milk72. Annual meeting of the european federation of animal science (EAAP), Aug 2021, Davos, Switzerland. pp.620
Communication dans un congrès
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MiRNA profile in milk extracellular vesicles is modulated by caprine alphaS1-casein genotype8. IDF International Symposium on Sheep, goat and other non-cow milk, Nov 2020, Inconnue, Belgium
Communication dans un congrès
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Une approche intégrée pour comprendre le dialogue entre tissus/organes chez les ruminants producteursJournées d’Animation Scientifique (JAS) du Département Physiologie Animale et Systèmes d'Elevage, Apr 2018, Rennes, France
Communication dans un congrès
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Des biomarqueurs aux outils de prédiction des performances des ruminants et de la qualité de leurs produitsJournées d’Animation Scientifique (JAS) du Département Physiologie Animale et Systèmes d'Elevage, Apr 2018, Rennes, France
Communication dans un congrès
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Les métabolites du lait comme indicateurs non invasifs du statut nutritionnel chez les vaches Holstein et Montbéliarde en milieu de lactation24. Rencontres autour des Recherches sur les Ruminants (3R), Dec 2018, Paris, France
Communication dans un congrès
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Milk fat globules as a source of mammary microRNAInternational Symposium on Microgenomics 2016, Jun 2016, Paris, France
Communication dans un congrès
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MilkChEST, an integrative approach of the secretion pathways in the mammary epithelial cell: molecular dissection of milk fat adaptabilityEuropean Regional Conference On Goats, Jun 2013, Tromsø, Norway
Communication dans un congrès
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Effet de la non alimentation sur le transcriptome adipocytaire de chèvres en lactation3. Journées d’Animation Scientifique du Département de Physiologie Animale et Systèmes d’Elevage, Oct 2009, Tours, France
Communication dans un congrès
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La nature du fourrage modifie la matière grasse laitière et le transcriptome mammaire de chèvres en lactation3. Journées d’Animation Scientifique du Département de Physiologie Animale et Systèmes d’Elevage, Oct 2009, Tours, France
Communication dans un congrès
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Transcriptomic profile in adipose tissues is modified by nutrition in lactating goats11. International Symposium on Ruminant Physiology, Sep 2009, Clermont-Ferrand, France
Communication dans un congrès
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Effect of nutrition on mammary transcriptome and its interaction with the CSN1S1 genotype in lactating goats.Journée Ecole Doctorale, Mars 2006., 2006, Inconnu, pp.Inconnu
Communication dans un congrès
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Impact of nutrition on mammary transcriptome and its interaction with the CSN1S1 genotype in lactating goats.3rd International Symposium on Milk Genomics & Human Health, Sep 2006, Bruxelles, pp.Inconnu
Communication dans un congrès
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Impact of nutrition on mammary transcriptome and its interaction with the CSN1S1 genotype in lactating goats57. Annual Meeting of the European Association for Animal Production (EAAP), Sep 2006, Antalya, Turkey
Communication dans un congrès
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Glucose-6-Phosphate dehydrogenase and leptin are linked to marbling differences between Limousin and angus or japanese black x angus steers56. Annual Meeting of the European Association for Animal Production (EAAP), Jun 2005, Uppsala, Sweden
Communication dans un congrès
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L'activité de la glucose-6-phosphate deshydrogenase est liée aux différences d'adiposite tissulaires et raciales chez le bovin en croissance1ères Journées d'Animation Scientifique du Département de Physiologie Animale et Systèmes d'Elevage, Mar 2005, Tours, France
Communication dans un congrès
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Effects of concentrate level and starch degradability on expression of mammary lipogenic genes in goats receiving a diet supplemented in sunflower oil56. Annual Meeting of the European Association for Animal Production (EAAP), Jun 2005, Uppsala, Sweden
Communication dans un congrès
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Effects of concentrate level and starch degradability on expression of mammary lipogenic genes in goats receiving a diet supplemented with sunflower oil3. International Workshop on Mammary Gland and Biotechnology : Nutrition, Genomics and Breast Cancer, Sep 2005, Barcelone, Spain
Communication dans un congrès
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Lipogenesis in subcutaneous adipose tissue and in oxidative or glycolytic muscles from Angus, Black Japanese x Angus and LimousinProgress in research on energy and protein metabolism, Sep 2003, Rostock-Warnemünde, Germany
Communication dans un congrès
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Effects of energy intake and photoperiod on the expression of genes encoding enzymes of energy metabolism in adipose tissue and muscle of ewes and cows3. Colloque Franco-Britannique de Nutrition : Fonctionnalité des nutriments, Sep 1998, Nancy, France
Communication dans un congrès
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Effect of refeeding on two mRNA species of lipoprotein lipase in adipose tissue and cardiac muscle of sheep3. French-British meeting on nutrition, Sep 1998, Nancy, France
Communication dans un congrès
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Quantitative fluorescence PCR assay for studing the expression of the gene encoding lipoprotein lipase in ovine adipose tissue25. ISAG Conference, Jul 1996, Tours, France
Communication dans un congrès
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Quantitative fluorescence PCR assay for studying the expression of the gene encoding lipoprotein lipase in ovine adipose tissue25. International conference on animal genetics, Jul 1996, Tours, France
Communication dans un congrès
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Study of lipoprotein lipase mRNAs in ovine adipose tissue by quantitative fluorescence polymerase chain reactionAnnual Symposium on Animal and Human Nutrition, Oct 1996, Nantes, France
Communication dans un congrès
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mRNAs encoding lipogenic and lipolytic enzymes in the adipose tissue of underfed-refed ewes and cows7. European congress on obesity, May 1996, Barcelone, Spain
Communication dans un congrès
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Nutritional Regulation of Mammary miRNome: Implications for Human StudiesHandbook of Nutrition, Diet, and Epigenetics, Editions Springer, 2017, 978-3-319-55530-0. ⟨10.1007/978-3-319-31143-2⟩
Chapitre d'ouvrage
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