Skip to Main content

Keywords

Co-authors

Researcher identifiers

Number of documents

59

Dr. Zohra BENFODDA


TITRES ET DIPlÔMES

 

2016 : Habilitation à diriger les recherches, Synthèses de molécules polyfonctionnelles à activité biologique potentielle. HDR soutenue le 21 novembre 2016 à l’université de Nîmes.

 

2006 : Doctorat (Bourse MENRT, Laboratoire OMEMF UMR 5073), Synthèses de sulfonamides, sulfonimides et sulfonylurées à chaîne perfluorée et polyfluorée. Etude de quelques propriétés biologiques. Thèse soutenue le 11 décembre 2006 à L’Université de Montpellier II (mention très honorable).

 

2003 : DEA de chimie des biomolécules : structure, synthèse et réactivité. Université de Montpellier II

 


Journal articles25 documents

  • Mame-Marietou Lo, Zohra Benfodda, David Bénimélis, Jean-Xavier Fontaine, Roland Molinié, et al.. Extraction and Identification of Volatile Organic Compounds Emitted by Fragrant Flowers of Three Tillandsia Species by HS-SPME/GC-MS. Metabolites, MDPI, 2021, 11 (9), pp.594. ⟨10.3390/metabo11090594⟩. ⟨hal-03334373⟩
  • Valentin Duvauchelle, Elsa Causse, Julien Michon, Patrick Rateau, Karine Weiss, et al.. Evaluation of Knowledge and Risk Perception about Antibiotic Resistance in Biology and Mathematics Young Students in Nîmes University in France. International Journal of Environmental Research and Public Health, MDPI, 2021, 18 (18), pp.9692. ⟨10.3390/ijerph18189692⟩. ⟨hal-03344418⟩
  • Mame-Marietou Lo, Zohra Benfodda, David Bénimélis, Jean-Xavier Fontaine, Roland Molinié, et al.. Development of a HS-SPME/GC-MS Method for the Extraction and Identification of the Volatile Compounds Emitted by Flowers of Tillandsia xiphioides. ACS Omega, ACS Publications, 2021, 6 (19), pp.12691-12698. ⟨10.1021/acsomega.1c00917⟩. ⟨hal-03243914⟩
  • Miyanou Rosales-Hurtado, Patrick Meffre, Hendrik Szurmant, Zohra Benfodda. Synthesis of histidine kinase inhibitors and their biological properties. Medicinal Research Reviews, Wiley, 2019, ⟨10.1002/med.21651⟩. ⟨hal-02400521⟩
  • Miyanou Rosales-Hurtado, Alexandre Lebeau, Cyril Bourouh, Gerardo Cebrian-Torrejon, Muriel Albalat, et al.. Improved synthesis, resolution, absolute configuration determination and biological evaluation of HLM006474 enantiomers. Bioorganic and Medicinal Chemistry Letters, Elsevier, 2019, 29, pp.380-382. ⟨10.1016/j.bmcl.2018.12.037⟩. ⟨hal-01968387⟩
  • Zohra Benfodda, David Bénimélis, Gianna Reginato, Patrick Meffre. Ethynylglycine synthon, a useful precursor for the synthesis of biologically active compounds: an update. Part II: synthetic uses of ethynylglycine synthon. Amino Acids, Springer Verlag, 2018, 50 (10), pp.1307-1328. ⟨10.1007/s00726-018-2628-1⟩. ⟨hal-01859944⟩
  • Florian Rouaud, Nedra Hamouda-Tekaya, Michaël Cerezo, Patricia Abbe, Joséphine Zangari, et al.. E2F1 inhibition mediates cell death of metastatic melanoma. Cell Death and Disease, Nature Publishing Group, 2018, 9 (5), pp.527. ⟨10.1038/s41419-018-0566-1⟩. ⟨inserm-02529927⟩
  • Lara Sassine, Corinne Le Gal La Salle, Mahmoud Khaska, Patrick Verdoux, Patrick Meffre, et al.. Spatial distribution of triazine residues in a shallow alluvial aquifer linked to groundwater residence time. Environmental Science and Pollution Research, Springer Verlag, 2017, 24 (8), pp.6878-6888. ⟨10.1007/s11356-016-7224-x⟩. ⟨hal-01544262⟩
  • Antonio Doménech-Carbó, Gerardo Cebrían-Torrejón, Noemínoemí Montoya, Nico Ueberschaar, Marcus Tullius Scotti, et al.. Electrochemical monitoring of ROS generation by anticancer agents: the case of chartreusin. RSC Advances, Royal Society of Chemistry, 2017, 7 (71), pp.45200 - 45210. ⟨10.1039/c7ra08238j⟩. ⟨hal-01676806⟩
  • Alexandre Lebeau, Cyril Abrioux, David Bénimèlis, Zohra Benfodda, Patrick Meffre. Synthesis of 1,4-disubstituted 1,2,3-triazole Derivatives Using Click Chemistry and their Src Kinase Activities. Medicinal Chemistry, Bentham Science Publishers, 2017, Medicinal Chemistry, 13, pp.40-48. ⟨10.2174/1573406412666160404125718⟩. ⟨hal-01495029⟩
  • Zohra Benfodda, Vanessa Fritz, Corinne Henriquet, Caterina Fattorusso, Gerardo Cebrian-Torrejon, et al.. Synthesis, Anticancer Activity and Computational SAR Analysis of Acylsulfonylpiperazines Derivatives. Medicinal Chemistry, Bentham Science Publishers, 2017, 7 (9), pp.257-267. ⟨10.4172/2161-0444.1000466⟩. ⟨hal-01662364⟩
  • Thibaut Boibessot, Christopher Zschiedrich, Alexandre Lebeau, David Bénimélis, Catherine Dunyach-Remy, et al.. The Rational Design, Synthesis, and Antimicrobial Properties of Thiophene Derivatives That Inhibit Bacterial Histidine Kinases. Journal of Medicinal Chemistry, American Chemical Society, 2016, pp.8830-8847. ⟨10.1021/acs.jmedchem.6b00580⟩. ⟨hal-01543599⟩
  • Thibaut Boibessot, David Bénimélis, Patrick Meffre, Zohra Benfodda. Advances in the synthesis of α‑quaternary α‑ethynyl α‑amino acids. Amino Acids, Springer Verlag, 2016, 48 (9), pp.2081-2101. ⟨10.1007/s00726-016-2276-2⟩. ⟨hal-01540958⟩
  • Thibaut Boibessot, David Bénimélis, Marion Jean, Zohra Benfodda, Patrick Meffre. Synthesis of a Novel Rhizobitoxine-Like Triazole-Containing Amino Acid. SYNLETT, Georg Thieme Verlag, 2016, 27 (19), pp.2685-2688. ⟨10.1055/s-0036-1588300⟩. ⟨hal-01404310⟩
  • Z Benfodda, David Bénimèlis, Marion Jean, Jean-Valère Naubron, Valerie Rolland, et al.. Synthesis, resolution, and determination of absolute configuration of protected α-ethynylphenylalanine enantiomers. Amino Acids, Springer Verlag, 2015, 47 (5), pp.899-907. ⟨10.1007/s00726-015-1917-1⟩. ⟨hal-02002634⟩
  • Zohra Benfodda, David Bénimélis, Gianna Reginato, Patrick Meffre. Ethynylglycine synthon, a useful precursor for the synthesis of biologically active compounds: an update: Part I: preparations of ethynylglycine synthon. Amino Acids, Springer Verlag, 2015, 47 (2), pp.271-279. ⟨10.1007/s00726-014-1902-0⟩. ⟨hal-01676812⟩
  • Zohra Benfodda, David Bénimélis, Marion Jean, Jean-Valère Naubron, Valérie Rolland, et al.. Synthesis, resolution, and determination of absolute configuration of protected α- [alpha]-ethynylphenylalanine enantiomers. Amino Acids, Springer Verlag, 2015, ⟨10.10007/s00726-015-1917-1⟩. ⟨hal-01274000⟩
  • Vivian Fritz, Zohra Benfodda, C. Henriquet, S Hure, Jean Paul Cristol, et al.. Metabolic intervention on lipid synthesis converging pathways abrogates prostate cancer growth. Oncogene, Nature Publishing Group, 2013, 32 (42), pp.5101-5110. ⟨10.1038/onc.2012.523⟩. ⟨hal-01274921⟩
  • Stéphanie Ortial, Rajesh Dave, Zohra Benfodda, David Bénimélis, Patrick Meffre. Synthesis of cis-5-Trifluoromethylproline from L-Glutamic Acid. SYNLETT, Georg Thieme Verlag, 2013, 2014 (25), pp.0569-0573. ⟨10.1055/s-0033-1340553⟩. ⟨hal-00969187⟩
  • Zohra Benfodda, Franck Guillen, Hubert Blancou. A Convenient Synthesis of N-Functionalized Perfluoroalkanesulfonamides. Phosphorus, Sulfur, and Silicon and the Related Elements, Taylor & Francis, 2010, 185 (9), pp.1905 - 1914. ⟨10.1080/10426500903362535⟩. ⟨hal-01702833⟩
  • Vanessa Fritz, Zohra Benfodda, Geneviève Rodier, Corinne Henriquet, François Iborra, et al.. Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice.: Lipid synthesis and cancer. Molecular Cancer Therapeutics, American Association for Cancer Research, 2010, 9 (6), pp.1740-54. ⟨10.1158/1535-7163.MCT-09-1064⟩. ⟨inserm-00544679⟩
  • Zohra Benfodda, Franck Guillen, Bernard Romestand, Abdelkader Dahmani, Hubert Blancou. Synthesis and investigation of inhibition effect of fluorinated sulfonamide derivatives on carbonic anhydrase. European Journal of Medicinal Chemistry, Elsevier, 2010, 45 (3), pp.1225-1229. ⟨10.1016/j.ejmrech2009.11.052⟩. ⟨hal-00555960⟩
  • Zohra Benfodda, Franck Guillen, Hélène Armion, Abdelkader Dahmani, Hubert Blancou. A New synthesis of alkane and polyfluoroalkanesulfonyl chlorides. Heteroatom Chemistry, Wiley, 2009, 20 (6), pp.355-361. ⟨10.1002/hc.20559⟩. ⟨hal-00555938⟩
  • Zohra Benfodda, Franck Guillen, Hubert Blancou. Synthesis of symmetric and dissymetric bisperfluoroalkanesulfonylimides and evaluation of their inhibition on bovine carbonic anhydrase. Heteroatom Chemistry, Wiley, 2008, 19 (5), pp.542 - 548. ⟨10.1002/hc.20452⟩. ⟨hal-01702775⟩
  • Zohra Benfodda, L. Delon, F. Guillen, H. Blancou. New synthesis of polyfluoroalkanesulfonylureas. Journal of Fluorine Chemistry, Elsevier, 2007, 128 (11), pp.1353 - 1358. ⟨10.1016/j.jfluchem.2007.05.022⟩. ⟨hal-01702758⟩

Conference papers13 documents

  • Zohra Benfodda. Séminaire invité : Synthèses de nouveaux agents antibactériens.. Séminaire invité Université des Antilles, Jun 2019, Pointe à Pitre, France. ⟨hal-02400596⟩
  • Zohra Benfodda, Miyanou Rosales-Hurtado, Thibaut Boibessot, Christopher Zschiedrich, Alexandre Lebeau, et al.. Rational design, synthesis and antimicrobial properties of thiophene derivatives that inhibit bacterial histidine kinases. 2nd international conference Antimicrobial and antibacterial Istanbul Turkey, Nov 2019, Istanbul, Turkey. ⟨hal-02400581⟩
  • Zohra Benfodda. Séminaire invité : Conception, synthèses, évaluation de l’activité biologique et de la biodégradabilité de nouveaux agents anti-bactériens. Séminaire invité à l'ENSIC, Feb 2018, Nancy, France. ⟨hal-01998552⟩
  • Zohra Benfodda, Thibaut Boibessot, Christopher Zschiedrich, Alexandre Lebeau, David Bénimèlis, et al.. Rational design, synthesis and antimicrobial properties of thiophene derivatives that inhibit bacterial histidine kinases. 24th ISCB international conference-Frontier research in chemistry&biology interface, Jan 2018, JAIPUR, India. ⟨hal-01998540⟩
  • Patrick Meffre, Zohra Benfodda, David Bénimèlis, Stéphanie Ortial, Valerie Rolland, et al.. Addendum to Abstracts presented at the 14th International Congress on Amino Acids, Peptides and Proteins. 14th International Congress on Amino Acids, Peptides and Proteins, Aug 2015, Vienna, Austria. pp.615-636. ⟨hal-02002708⟩
  • Stéphanie Ortial, Rajesh Dave, Zohra Benfodda, David Bénimèlis, Patrick Meffre. Synthesis of 5-trifluoromethylproline from L-glutamic acid. 14th International Congress on Amino Acids, Peptides and Proteins, Aug 2015, Wien, Austria. pp.615-636, ⟨10.1007/s00726-015-2160-5⟩. ⟨hal-02010135⟩
  • Zohra Benfodda, Stéphanie Ortial, David Bénimélis, Valerie Rolland, Patrick Meffre. Synthesis of acetylenic analogue of phenylalanine.. 13th International Congress on Amino acids, peptides and proteins, Oct 2013, Galvestion (Texas), United States. pp.611, ⟨10.1007/s00726-013-1540-y⟩. ⟨hal-00993416⟩
  • Patrick Meffre, Stéphanie Ortial, David Bénimèlis, Valerie Rolland, Zohra Benfodda. Synthesis of acetylenic analogue of phenylalanine. 13th International Congress on Amino acids, peptides and proteins, Oct 2013, Galveston, United States. pp.563-612, ⟨10.1007/s00726-013-1540-y⟩. ⟨hal-02010130⟩
  • Patrick Meffre, Zohra Benfodda, David Bénimélis, Valérie Rolland, Francine Acher. New developments in the synthesis of acetylenic analogues of glutamate. 12 th International Congress on Amino Acids, Peptides and Proteins, Aug 2011, Beijing, China. pp.S79. ⟨hal-00621161⟩
  • Patrick Meffre, Zohra Benfodda, David Bénimèlis, Valerie Rolland, Francine C. Acher. New developements in the synthesis of acetylenic analogues of glutamate. 12th International Congress on Amino Acids, Peptides and Proteins, Aug 2011, Beijing, China. pp.1-86, ⟨10.1007/s00726-011-0955-6⟩. ⟨hal-02010128⟩
  • Zohra Benfodda, David Bénimèlis, Patrick Meffre, Francine Acher. Synthesis of acetylenic analogues of glutamate. 10th International Congress on amino acids and proteins, Aug 2007, Kallithea, Greece. ⟨hal-01998510⟩
  • Patrick Meffre, Zohra Benfodda, David Bénimèlis, Guillaume Vierling, Francine C. Acher. Synthesis of acetylenic analogues of glutamate. 10th International Congress on Amino Acids and Proteins (ICAAP), Aug 2007, Kalithea, Chalkidiki, Greece. pp.I-LXX, ⟨10.1007/s00726-007-0578-0⟩. ⟨hal-02010124⟩
  • Zohra Benfodda, Franck Guillen, Hubert Blancou. Application of highly fluorinated sulfonamides. Université d’été européenne IBMM, Sep 2006, montpellier, France. ⟨hal-01998499⟩

Poster communications19 documents

  • Linda Matignon, Mame Marietou Lo, Antonio Doménech-Carbó, Muriel Sylvestre, Patrick Meffre, et al.. Trophic interactions between Pseudosphinx tetrio larvae and Allamanda cathartica. Caribbean Science and Innovation Meeting 2019, Oct 2019, Pointe-à-Pitre (Guadeloupe), France. ⟨hal-02893707⟩
  • Valentin Duvauchelle, Miyanou Rosales-Hurtado, Thibaut Boibessot, David Bénimèlis, Catherine Dunyach-Remy, et al.. Synthesis and biological evaluations of new families of histidine kinases inhibitors. GSO-JMJC-JED2019, Oct 2019, Montpellier, France. ⟨hal-02333120⟩
  • Zohra Benfodda, Gerardo Cebrian-Torrejon, Bourguet Romane, Sciortino Giuseppe, Jean-Didier Maréchal, et al.. Design and synthesis of novel HLM 006474 derivatives.. 24th ISCB international conference-Frontier research in chemistry&biology interface., Jan 2018, JAIPUR, India. ⟨hal-01998366⟩
  • Miyanou Rosales-Hurtado, Thibaut Boibessot, Christopher Zschiedrich, Alexandre Lebeau, David Bénimélis, et al.. Synthesis of thiophene derivatives: Potential new inhibitors of histidine kinases. Rencontres en Chimie Organique Biologique (Recob 17), Mar 2018, Aussois, France. ⟨hal-01997587⟩
  • Patrick Meffre, Miyanou Rosales-Hurtado, Alexandre Lebeau, Gerardo Cebrian-Torrejon, Muriel Albalat, et al.. Improved synthesis, resolution, absolute configuration determination of HLM006474 enantiomer. XXII International conférence on Organic synthesis (22-ICOS), Sep 2018, Florence, Italy. ⟨hal-02011288⟩
  • Patrick Meffre, Thibaut Boibessot, David Bénimèlis, Zohra Benfodda. Synthesis of Novel Triazole Amino Acids Analogues of Natural Amino Acids. 20th European symposium on Organic Chemistry (ESOC), Jul 2017, Cologne, Germany. ⟨hal-02011261⟩
  • Zohra Benfodda, Christopher Zschiedrich, Alexandre Lebeau, Thibaut Boibessot, Marta Maria Perego, et al.. Rational design of potent histidine kinase inhibitors with antimicrobial activities.. Experimental Biology meeting in San Diego, Apr 2016, San Diego, United States. ⟨hal-01998350⟩
  • Zohra Benfodda, Christopher Zschiedrich, Alexandre Lebeau, Thibaut Boibessot, Patrick Meffre, et al.. Rational design of potent histidine kinase inhibitors with antimicrobial activities. 8ème congrès international sur les microorganismes gram-positive, Jun 2015, Montecatini, Italy. ⟨hal-01998292⟩
  • Zohra Benfodda, Alexandre Lebeau, David Bénimèlis, Hendrik Szurmant, Patrick Meffre. Design and synthesis of 1,4-disubstituted 1,2,3-triazole derivatives as Histidine Kinase inhibitor.. 77th Harden Conference: Two Component Signalling in Bacteria: Integrating Approaches and Science, Aug 2015, Warwickshire, United Kingdom. ⟨hal-01998338⟩
  • Zohra Benfodda, Thibaut Boibessot, Alexandre Lebeau, David Bénimèlis, Patrick Meffre. Synthesis of triazole amino acids. 14th International Congress on Amino Acids, Peptides and Proteins, Aug 2015, Vienne, Austria. ⟨hal-01998273⟩
  • Zohra Benfodda, David Bénimèlis, Valérie Rolland, Patrick Meffre. Synthesis of ethynyl phenylalanine. The 5th European Chemistry Congress, Aug 2014, Istanbul, Turkey. ⟨hal-01998193⟩
  • Zohra Benfodda, David Benimelis, Valerie Rolland, Thibaut Boibessot, Patrick Meffre. Synthesis of ethynyl phenylalanine. 21ème journée de l’Institut de Recherche Pierre Fabre (IRPF) de chimie. Chambre de commerce et d’industrie de Castres, Sep 2014, Castres, France. ⟨hal-01998205⟩
  • Zohra Benfodda, Vanessa Fritz, Corinne Henriquet, Lluis Fajas. Abrogation of de novo lipogenesis by SCD-1 inhibition interferes with oncogenic signaling, and blocks prostate cancer progression in mice. FASEB Lipid signaling pathways in cancer, Jul 2009, Carefree Arizona, United States. ⟨hal-01998168⟩
  • Zohra Benfodda, Vanessa Fritz, Corinne Henriquet, Lluis Fajas. The intermediary metabolism in prostate cancer : new targets for an old disease.. Les 4èmes journées du Cancéropole Grand Sud Ouest, Oct 2009, Montpellier, France. ⟨hal-01998136⟩
  • Zohra Benfodda, Vanessa Fritz, Corinne Henriquet, Lluis Fajas. Abrogation of de novo lipogenesis by SCD-1 inhibition interferes with oncogenic signaling, and blocks prostate cancer progression in mice. American Association for Cancer Research : metabolism and cancer, Aug 2009, San Diego, United States. ⟨hal-01998177⟩
  • Zohra Benfodda, Franck Guillen, Hubert Blancou. Synthesis of new highly fluorinated sulfonamides and their application.. Journée IBMM en l’honneur du Pr Curran, Apr 2007, Montpellier, France. ⟨hal-01998127⟩
  • Zohra Benfodda, Franck Guillen, Hubert Blancou. Synthèse de sulfamides carbofluorés et carbohydrogénés inhibiteurs de l’anhydrase carbonique.. SAJEC, Oct 2006, Balaruc les Bains, France. ⟨hal-01998119⟩
  • Zohra Benfodda, Franck Guillen, Hubert Blancou. Synthesis of new highly fluorinated sulfonamides and their application.. The first European Chemistry Congress, Aug 2006, Budapest, Hungary. ⟨hal-01998109⟩
  • Zohra Benfodda, Hubert Blancou, Franck Guillen. Synthèse de sulfamides carbofluorés et carbohydrogénés inhibiteurs de l’anhydrase carbonique.. Journée Chimie Grand Sud-Ouest, Nov 2005, Montpellier, France. ⟨hal-01998091⟩

Patents2 documents

  • Lluis Fajas, Zohra Benfodda, Vanessa Fritz. NOVEL INHIBITORS OF STEAROYL-CoA-DESATURASE-1 AND THEIR USES. France, Patent n° : WO 2011/030312 A1. 2011. ⟨hal-01997601⟩
  • Zohra Benfodda, Franck Guillen, Hubert Blancou. Pharmaceutical compositions based on fluorinated sulphamides and sulphinimides. France, N° de brevet: WO2006/067330 A1. 2005. ⟨hal-01998479⟩