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Yves Le Loir
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Documents
Présentation
**Yves Le Loir** is a research scientist working at the French National Institute for Agricultural Research (INRA). He dedicates his scientific carrier to the microbiology of the milk production chain (with food and veterinary aspects). He originally studied Biochemistry at the University of Rennes (France). In 1992, he passed the diploma of Engineer in Agronomy of the Ecole Nationale Supérieure d’Agronomie (ENSA), in Rennes. He moved to INRA Jouy en Josas, France, (Unit of Microbial Genetics, headed by S.D. Ehrlich) to work on conjugative DNA transfer in *Lactococcus lactis*, the model lactic acid bacterium (LAB). He stayed in the same team to prepare a PhD thesis (University of Paris XI) in Microbiology on heterologous proteins secretion in *L. lactis*. He defended in 1996 and was recruited in INRA to go on working on protein secretion and lately on respiration in *L. lactis*. In February 2001, Y. Le Loir moved to INRA Rennes to start a new laboratory (Unit of Microbiology, INRA ENSA, Rennes, France). His new projects focused on host adaptation (ruminants) in *Staphylococcus aureus* and interactions between *Staphylococcus aureus* and Lactic Acid Bacteria. In 2008-2016, he headed a research team (12 permanent positions) called Bacterial Biodiversity and In Situ Interactions. From 2011 to 2016, he was alos deputy director of the Research Unit STLO. Since January 2017, he is heading the STLO Unit in Rennes. **STLO (Science and Technology of Milk & Eggs)** is a joint research unit comprising INRA and Agrocampus Ouest staff members (83 permanent positions, 130-140 staff). Since 2000, Y. Le Loir tightly collaborates with Pr Vasco Azevedo (UFMG, Belo Horizonte) and he has been Pesquisador Visitante Especial at UFMG in 2014-2016 (PVE400721/2013-9; CNPq). He also coordinates an International Associated Laboratory involving STLO and Micalis Research Units at INRA and 3 research teams at UFMG, in Brazil.
Publications
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The genomic basis of the Streptococcus thermophilus health-promoting propertiesBMC Genomics, 2022, 23, pp.1-23. ⟨10.1186/s12864-022-08459-y⟩
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Permanent draft genome sequence of the probiotic strain Propionibacterium freudenreichii CIRM-BIA 129 (ITG P20).Standards in Genomic Sciences, 2016, 11, pp.6. ⟨10.1186/s40793-015-0120-z⟩
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Mutations and genomic islands can explain the strain dependency of sugar utilization in 21 strains of Propionibacterium freudenreichiiBMC Genomics, 2015, 16 (1), pp.35. ⟨10.1186/s12864-015-1467-7⟩
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Lactic Acid Bacteria Isolated from Bovine Mammary Microbiota: Potential Allies against Bovine MastitisPLoS ONE, 2015, 10 (12), pp.1-18. ⟨10.1371/journal.pone.0144831⟩
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Les bactéries du lait maternel humain, individuellement ou assemblées en communautés synthétiques, ont un impact sur les fonctions immunitaire et barrière intestinales, in vitro.18e congrès national de la SFM « Un monde à explorer », Société Française de Microbiologie (SFM), Oct 2023, Rennes, France
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Human milk bacteria individually or as a synthetic community exhibited contrasted immunomodulatory profiles and impact on the gut epithelial barrierThe 10th Beneficial Microbes Conference, Beneficial Microbes Consultancy and University of Maastricht, the Netherlands, Dec 2023, Amsterdam, Netherlands
Communication dans un congrès
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Milk microbiota: facts, open questions and roles for mother and offspring health8. Beneficial Microbes Conference, Mar 2021, Virtual Conference, Netherlands
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Immunomodulatory potential of bacteria isolated from human breast milk on different cellular modelsPoster de conférence hal-03694103v1 |
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The genomic basis of the Streptococcus thermophilus health-promoting propertiesJOBIM 2022 - Les journées Ouvertes en Biologie, Informatique et Mathématiques, Jul 2022, Rennes, France. , pp.1-1, 2022
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Mutations and genomic islands can explain the strain dependency of sugar utilization in 21 strains of Propionibacterium freudenreichiiJOBIM 16. Journées Ouvertes de Biologie, Informatique et Mathématiques, Jul 2015, Clermont-Ferrand, France. , 2015, ⟨10.1186/s12864-015-1467-7⟩
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Des bactéries lactiques, alliées potentielles contre les mammites bovinesPoster de conférence hal-01204475v1 |
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Mutations and genomic islands can explain the strain dependency of sugar utilization in 21 strains of Propionibacterium freudenreichiiPoster de conférence hal-01170054v1 |