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Yves Le Loir

19
Documents

Présentation

**Yves Le Loir** is a research scientist working at the French National Institute for Agricultural Research (INRA). He dedicates his scientific carrier to the microbiology of the milk production chain (with food and veterinary aspects). He originally studied Biochemistry at the University of Rennes (France). In 1992, he passed the diploma of Engineer in Agronomy of the Ecole Nationale Supérieure d’Agronomie (ENSA), in Rennes. He moved to INRA Jouy en Josas, France, (Unit of Microbial Genetics, headed by S.D. Ehrlich) to work on conjugative DNA transfer in *Lactococcus lactis*, the model lactic acid bacterium (LAB). He stayed in the same team to prepare a PhD thesis (University of Paris XI) in Microbiology on heterologous proteins secretion in *L. lactis*. He defended in 1996 and was recruited in INRA to go on working on protein secretion and lately on respiration in *L. lactis*. In February 2001, Y. Le Loir moved to INRA Rennes to start a new laboratory (Unit of Microbiology, INRA ENSA, Rennes, France). His new projects focused on host adaptation (ruminants) in *Staphylococcus aureus* and interactions between *Staphylococcus aureus* and Lactic Acid Bacteria. In 2008-2016, he headed a research team (12 permanent positions) called Bacterial Biodiversity and In Situ Interactions. From 2011 to 2016, he was alos deputy director of the Research Unit STLO. Since January 2017, he is heading the STLO Unit in Rennes. **STLO (Science and Technology of Milk & Eggs)** is a joint research unit comprising INRA and Agrocampus Ouest staff members (83 permanent positions, 130-140 staff). Since 2000, Y. Le Loir tightly collaborates with Pr Vasco Azevedo (UFMG, Belo Horizonte) and he has been Pesquisador Visitante Especial at UFMG in 2014-2016 (PVE400721/2013-9; CNPq). He also coordinates an International Associated Laboratory involving STLO and Micalis Research Units at INRA and 3 research teams at UFMG, in Brazil.

Publications

pierre-germon
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Microbiota members from body sites of dairy cows are largely shared within individual hosts throughout lactation but sharing is limited in the herd

Mahendra Mariadassou , Laurent-Xavier Nouvel , Fabienne Constant , Diego P. Morgavi , Lucie Rault
Animal Microbiome, 2023, 5 (1), pp.32. ⟨10.1186/s42523-023-00252-w⟩
Article dans une revue hal-04126196v1
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Transcriptome Architecture of Osteoblastic Cells Infected With Staphylococcus aureus Reveals Strong Inflammatory Responses and Signatures of Metabolic and Epigenetic Dysregulation

Aurélie Nicolas , Martine Deplanche , Pierre-Henri Commere , Alan Diot , Clemence Genthon
Frontiers in Cellular and Infection Microbiology, 2022, 12, pp.854242. ⟨10.3389/fcimb.2022.854242⟩
Article dans une revue hal-03650997v1

Bovine Teat Cistern Microbiota Composition and Richness Are Associated With the Immune and Microbial Responses During Transition to Once-Daily Milking

Lucie Rault , Pierre-Alexandre Lévêque , Sarah Barbey , Frederic Launay , Hélène Larroque
Frontiers in Microbiology, 2020, 11, 13 p. ⟨10.3389/fmicb.2020.602404⟩
Article dans une revue hal-03106273v1

Staphylococcus aureus Phenol-Soluble Modulins Impair Interleukin Expression in Bovine Mammary Epithelial Cells

Martine Deplanche , Ludmila Alekseeva , Ksenia Semenovskaya , Chih Lung Fu , Frederic Dessauge
Infection and Immunity, 2016, 84 (6), pp.1682-1692. ⟨10.1128/IAI.01330-15⟩
Article dans une revue hal-01454608v1
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Lactic Acid Bacteria Isolated from Bovine Mammary Microbiota: Potential Allies against Bovine Mastitis

Damien Bouchard , Bianca Seridan de Assis , Taous Saraoui , Lucie Rault , Pierre Germon
PLoS ONE, 2015, 10 (12), pp.1-18. ⟨10.1371/journal.pone.0144831⟩
Article dans une revue hal-01251256v1

Lactococcus lactis V7 inhibits the cell invasion of bovine mammary epithelial cells by Escherichia coli and Staphylococcus aureus.

Bianca Seridan de Assis , Pierre Germon , a M Silva , Sergine Even , J R Nicoli
Beneficial Microbes, 2015, 6 (6), pp.879-886. ⟨10.3920/BM2015.0019⟩
Article dans une revue hal-01454528v1

Milk microbiota: potential allies for mammary gland health

Coralie Goetz , Lucie Rault , Marion Boutinaud , Christine Citti , Hélène Falentin
ADSA annual meeting 2023, American Dairy Science Association, Jun 2023, Ottawa, Canada. pp.146
Communication dans un congrès hal-04164763v1
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Unveiling the Secrets of Long-Term Staphylococcus aureus Infections: Insights into Inflammation, Metabolism, and Epigenetic Changes from Non-Immune Cells Transcriptomes

Aurélie Nicolas , Martine Deplanche , Sandrine Péron , Pierre-Henri Commere , Alan Diot
Rendez-vous scientifique annuel d’Op+lait Réunion glande Mammaire lait, Galactinov, Réseau Oplait-Galctinov, Oct 2023, Québec (online), Canada
Communication dans un congrès hal-04251786v1

[i]Staphylococcus aureus[/i] phenol-soluble modulins impair interleukin expression in bovine mammary epithelial cells.

Martine Deplanche , Liudmila Alekseeva , Ksenia Semenovskaya , Chih-Lung Fu , Frederic Dessauge
Journées d'Animation Scientifique du Département Santé Animale, Institut National de Recherche Agronomique (INRA). UMR Infectiologie et Santé Publique (1282)., May 2016, Poitiers, France
Communication dans un congrès hal-01352689v1

Exploration of dairy cow holobiont revealed an important sharing of microbes between anatomic sites within individual hosts throughout lactation but sharing was limited in the herd

Mahendra Mariadassou , Laurent-Xavier Nouvel , Fabienne Constant , Diego Morgavi , Lucie Rault
https://www.adsa.org/Meetings/2023-Annual-Meeting. ADSA annual meeting 2023, Jun 2023, Ottawa, Canada. , 2023
Poster de conférence hal-04164713v1
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New insights into cow holobiont in relation to heath

Sergine Even , Mahendra Mariadassou , Xavier Nouvel , Fabienne F. Constant , Diego Morgavi
16e congres national de la SFM-MICROBES 2021, Sep 2021, Nantes, France
Poster de conférence hal-03361039v1
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Bovine mammary gland microbiota et immune response

Sergine Even , Lucie Rault , Pierre-Alexandre Lévêque , Sarah Barbey , Frederic Launay
16e congres national de la SFM- MICROBES 2021, Sep 2021, Nantes, France. , 2021
Poster de conférence hal-03361030v1

New insights into cow holobiont in relation to health

Mahendra Mariadassou , Laurent-Xavier Nouvel , Diego Morgavi , Lucie Rault , Sophie Schbath
Journées Ouvertes de Biologie, Informatique et Mathématique (JOBIM), Jun 2020, Montpellier, France. , 2020
Poster de conférence hal-02962468v1

Immune response in relation to bovine mammary gland microbiome during transition to once-a-day milking

Lucie Rault , Jocelyne Guinard-Flament , Pierre-Alexandre Leveque , Sarah Barbey , Frédéric Launay
Pathobiome 2018 "Pathogens in Microbiotas in Hosts", Mar 2018, Ajaccio, France. , 2018
Poster de conférence hal-02734222v1

New insights into cow holobiont in relation to health

Laurent-Xavier Nouvel , Diego Morgavi , Lucie Rault , Mahendra Mariadassou , Sophie Schbath
Pathobiome 2018 "Pathogens in Microbiotas in Hosts", Jan 2018, Ajaccio, France
Poster de conférence hal-03299131v1

Phenol-soluble modulins alpha induce G2/M phase transition delay and impair immune response of eukaryotic cells

Martine Deplanche , Rachid El-Aouar Filho , Ksenia Semenovskaya , Liudmila Alekseeva , Julien Jardin
ICI 2016 International Congress of Immunology, Aug 2016, Melbourne, Australia. John Wiley and Sons, European Journal of Immunology, 46 Supplement: 1 Special Issue: SI Meeting Abstract: 1425, pp.1: 351, 2016, European Journal of Immunology
Poster de conférence hal-01389063v1

Staphylococcus aureus phenol-soluble modulins impair interleukin expression in bovine mammary epithelial cells

Martine Deplanche , Liudmila Alekseeva , Ksenia Semenovskaya , Chih-Lung Fu , Frederic Dessauge
Journées d'Animation Scientifique du Département Santé Animale, May 2016, Chasseneuil-du-Poitou, France. 98 p., 2016
Poster de conférence hal-01454659v1

Des bactéries lactiques, alliées potentielles contre les mammites bovines

Damien Bouchard , Bianca Seridan de Assis , Taous Saraoui , Lucie Rault , Pierre Germon
20. Edition du Club des Bactéries Lactiques, Jun 2015, Lille, France. , 2015
Poster de conférence hal-01204475v1

S. aureus and E. coli induce IL-32 gene expression to different extents during infection of bovine mammary gland epithelial cells

Martine Deplanche , L. Alexeeva , Pierre Germon , Pascal Rainard , Frederic Dessauge
4. European Congress of Immunology, Sep 2015, Vienne, Austria. , 2015, Abstract book
Poster de conférence hal-01454530v1