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Yves Le Loir

16
Documents

Présentation

**Yves Le Loir** is a research scientist working at the French National Institute for Agricultural Research (INRA). He dedicates his scientific carrier to the microbiology of the milk production chain (with food and veterinary aspects). He originally studied Biochemistry at the University of Rennes (France). In 1992, he passed the diploma of Engineer in Agronomy of the Ecole Nationale Supérieure d’Agronomie (ENSA), in Rennes. He moved to INRA Jouy en Josas, France, (Unit of Microbial Genetics, headed by S.D. Ehrlich) to work on conjugative DNA transfer in *Lactococcus lactis*, the model lactic acid bacterium (LAB). He stayed in the same team to prepare a PhD thesis (University of Paris XI) in Microbiology on heterologous proteins secretion in *L. lactis*. He defended in 1996 and was recruited in INRA to go on working on protein secretion and lately on respiration in *L. lactis*. In February 2001, Y. Le Loir moved to INRA Rennes to start a new laboratory (Unit of Microbiology, INRA ENSA, Rennes, France). His new projects focused on host adaptation (ruminants) in *Staphylococcus aureus* and interactions between *Staphylococcus aureus* and Lactic Acid Bacteria. In 2008-2016, he headed a research team (12 permanent positions) called Bacterial Biodiversity and In Situ Interactions. From 2011 to 2016, he was alos deputy director of the Research Unit STLO. Since January 2017, he is heading the STLO Unit in Rennes. **STLO (Science and Technology of Milk & Eggs)** is a joint research unit comprising INRA and Agrocampus Ouest staff members (83 permanent positions, 130-140 staff). Since 2000, Y. Le Loir tightly collaborates with Pr Vasco Azevedo (UFMG, Belo Horizonte) and he has been Pesquisador Visitante Especial at UFMG in 2014-2016 (PVE400721/2013-9; CNPq). He also coordinates an International Associated Laboratory involving STLO and Micalis Research Units at INRA and 3 research teams at UFMG, in Brazil.

Publications

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Extracellular vesicles from Staphylococcus aureus follow different pathways to manipulate host cells

Julia Papail , Ligia Prado , Nathalie Daniel , Brenda Silva Rosa da Luz , Daniele Vassaux
18e congrès national de la SFM « Un monde à explorer », Société Française de Microbiologie (SFM), Oct 2023, Rennes, France
Communication dans un congrès hal-04234337v1
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Interaction mechanisms with host of EVs derived from the opportunistic pathogen Staphylococcus aureus

Julia Papail , Ligia Prado , Nathalie Daniel , Daniele Vassaux , Yann Le Gouar
Journée GO-EVs sur les vésicules extracellulaires, INRAE, Oct 2023, NANTES, France
Communication dans un congrès hal-04257450v1

New Insights into Host-Pathogen Interactions of Staphylococcus aureus: Involvement of Extracellular Vesicles to Manipulate Host Cells

Julia Papail , Ligia Prado , Nathalie Daniel , Brenda Silva Rosa da Luz , Yann Le Gouar
Staphosium 2023, Le groupe de travail « staphylococci » organise son premier colloque. L’ objectif est de stimuler le réseau pour l’ensemble des acteurs travaillant sur les staphylocoques afin de faciliter les échanges et les collaborations., Nov 2023, LYON, France
Communication dans un congrès hal-04299256v1
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Development of trained immunity and activation of inflammasomes are promising strategies to combat Staphylococcus aureus infection

Emmanuel Chaumond , Elma Lima Leite , Sandrine Péron , Nathalie Daniel , Yann Le Gouar
18e congrès national de la SFM « Un monde à explorer », Société Française de Microbiologie (SFM), Oct 2023, Rennes, France
Communication dans un congrès hal-04234405v1
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Unveiling the Secrets of Long-Term Staphylococcus aureus Infections: Insights into Inflammation, Metabolism, and Epigenetic Changes from Non-Immune Cells Transcriptomes

Aurélie Nicolas , Martine Deplanche , Sandrine Péron , Pierre-Henri Commere , Alan Diot
Rendez-vous scientifique annuel d’Op+lait Réunion glande Mammaire lait, Galactinov, Réseau Oplait-Galctinov, Oct 2023, Québec (online), Canada
Communication dans un congrès hal-04251786v1
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Inflammasome activation and an involvement of Caspase-1 in a bacterial clearance during S. aureus infection.

Elma Lima Leite , Aurélie Nicolas , Arthur Gautron , Martine Deplanche , Jordane Ossemond
Bactinflan, Lia Bactinflam, INRAE STLO, Jun 2022, Webinar, France
Communication dans un congrès hal-03690660v1

Exfoliative toxin E, a new Staphylococcus aureus virulence factor with host-specific activity

I. Imanishi , Aurélie Nicolas , A.C. B. Caetano , Thiago Luiz de Paula Castro , Natayme Rocha Tartaglia
Microbes, 15e Congrès National de la SFM, Sep 2019, Paris, France
Communication dans un congrès hal-02306146v1

Staphylococcus aureus extracellular vesicles elicit an immunostimulatory response in vivo on the murine mammary gland

Yves Le Loir , Eric Guédon , Natayme Rocha Tartaglia , Koen Breyne , Evelyne Meyer
14.congrès national de la Société Française de Microbiologie (SFM), Oct 2018, Paris, France
Communication dans un congrès hal-01889276v1

Staphylococcus aureus-derived extracellular vesicles induce an inflammatory response in murine model of mastitis

Natayme Rocha Tartaglia , Koene Breyne , Kristel Demeyere , Julien Jardin , Chantal Cauty
Congrès FSEV 2017, Nov 2017, Paris, France
Communication dans un congrès hal-01645112v1
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Unleashing the power of inflammasomes and trained immunity: promising strategies in the fight against Staphylococcus aureus infection

Emmanuel Chaumond , Elma Lima Leite , Nathalie Daniel , Sandrine Peron , Yann Le Gouar
https://immunologisk-selskab.dk/calendar/lofoten-immunology-workshop-2023/. Lofoten Immunology Workshop 2023, Aug 2023, Lofoten Islands, Norway. , 2023
Poster de conférence hal-04195275v1
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Involvement of Extracellular Vesicles from Staphylococcus aureus in host cells manipulation

Julia Papail , Ligia Prado , Nathalie Daniel , Yann Le Gouar , Nadia Berkova
GENÉTICA 23 – 68th Brazilian Congress of Genetics 2023, Sep 2023, Ouro Preto – MG, Brazil. , 2023
Poster de conférence hal-04215082v1
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Staphylococcus aureus induces DNA damage in host cell

Nadia Berkova , Nassim Mouhali , Aurélie Nicolas , Martine Deplanche , Minh-Thu Nguyen
Journées d’Animation Scientifique du Département Santé Animale, Oct 2022, Anglet, France. , 2022
Poster de conférence hal-03859134v1