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Yves Le Loir

14
Documents

Présentation

**Yves Le Loir** is a research scientist working at the French National Institute for Agricultural Research (INRA). He dedicates his scientific carrier to the microbiology of the milk production chain (with food and veterinary aspects). He originally studied Biochemistry at the University of Rennes (France). In 1992, he passed the diploma of Engineer in Agronomy of the Ecole Nationale Supérieure d’Agronomie (ENSA), in Rennes. He moved to INRA Jouy en Josas, France, (Unit of Microbial Genetics, headed by S.D. Ehrlich) to work on conjugative DNA transfer in *Lactococcus lactis*, the model lactic acid bacterium (LAB). He stayed in the same team to prepare a PhD thesis (University of Paris XI) in Microbiology on heterologous proteins secretion in *L. lactis*. He defended in 1996 and was recruited in INRA to go on working on protein secretion and lately on respiration in *L. lactis*. In February 2001, Y. Le Loir moved to INRA Rennes to start a new laboratory (Unit of Microbiology, INRA ENSA, Rennes, France). His new projects focused on host adaptation (ruminants) in *Staphylococcus aureus* and interactions between *Staphylococcus aureus* and Lactic Acid Bacteria. In 2008-2016, he headed a research team (12 permanent positions) called Bacterial Biodiversity and In Situ Interactions. From 2011 to 2016, he was alos deputy director of the Research Unit STLO. Since January 2017, he is heading the STLO Unit in Rennes. **STLO (Science and Technology of Milk & Eggs)** is a joint research unit comprising INRA and Agrocampus Ouest staff members (83 permanent positions, 130-140 staff). Since 2000, Y. Le Loir tightly collaborates with Pr Vasco Azevedo (UFMG, Belo Horizonte) and he has been Pesquisador Visitante Especial at UFMG in 2014-2016 (PVE400721/2013-9; CNPq). He also coordinates an International Associated Laboratory involving STLO and Micalis Research Units at INRA and 3 research teams at UFMG, in Brazil.

Publications

"aurelie-nicolas"
"nadejda-nadia-berkova"
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Transcriptome Architecture of Osteoblastic Cells Infected With Staphylococcus aureus Reveals Strong Inflammatory Responses and Signatures of Metabolic and Epigenetic Dysregulation

Aurélie Nicolas , Martine Deplanche , Pierre-Henri Commere , Alan Diot , Clemence Genthon
Frontiers in Cellular and Infection Microbiology, 2022, 12, pp.854242. ⟨10.3389/fcimb.2022.854242⟩
Article dans une revue hal-03650997v1
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Involvement of caspase-1 in inflammasomes activation and bacterial clearance in S. aureus-infected osteoblast-like MG-63 cells

Elma Lima Leite , Arthur Gautron , Martine Deplanche , Aurélie Nicolas , Jordane Ossemond
Cellular Microbiology, 2020, 22 (8), pp.e13204. ⟨10.1111/cmi.13204⟩
Article dans une revue hal-02565096v1
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Author correction: exfoliative toxin e, a new Staphylococcus aureus virulence factor with host-specific activity

Ichiro Imanishi , Aurélie Nicolas , Ana-Carolina Barbosa Caetano , Thiago Luiz de Paula Castro , Natayme Rocha Tartaglia
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-59360-1⟩
Article dans une revue hal-03359247v1
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Exfoliative toxin E, a new Staphylococcus aureus virulence factor with host-specific activity

Ichiro Imanishi , Aurélie Nicolas , Ana-Carolina Barbosa Caetano , Thiago Luiz de Paula Castro , Natayme Rocha Tartaglia
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-52777-3⟩
Article dans une revue hal-02625122v1
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Heterogeneous Family of Cyclomodulins: Smart Weapons That Allow Bacteria to Hijack the Eukaryotic Cell Cycle and Promote Infections

Rachid A. El-Aouar Filho , Aurélie Nicolas , Thiago L. de Paula Castro , Martine Deplanche , Vasco A. de Carvalho Azevedo
Frontiers in Cellular and Infection Microbiology, 2017, 7, pp.208. ⟨10.3389/fcimb.2017.00208⟩
Article dans une revue hal-03359289v1
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Corrigendum: Heterogeneous Family of Cyclomodulins: Smart Weapons That Allow Bacteria to Hijack the Eukaryotic Cell Cycle and Promote Infections

Rachid El-Aouar Filho , Aurélie Nicolas , Thiago Luiz de Paula Castro , Vasco Ariston de Carvalho Azevedo , Pierre L. Goossens
Frontiers in Cellular and Infection Microbiology, 2017, 7 (article 208), pp.364. ⟨10.3389/fcimb.2017.00208⟩
Article dans une revue hal-01594586v1
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Development of trained immunity and activation of inflammasomes are promising strategies to combat Staphylococcus aureus infection

Emmanuel Chaumond , Elma Lima Leite , Sandrine Péron , Nathalie Daniel , Yann Le Gouar
18e congrès national de la SFM « Un monde à explorer », Société Française de Microbiologie (SFM), Oct 2023, Rennes, France
Communication dans un congrès hal-04234405v1
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Unveiling the Secrets of Long-Term Staphylococcus aureus Infections: Insights into Inflammation, Metabolism, and Epigenetic Changes from Non-Immune Cells Transcriptomes

Aurélie Nicolas , Martine Deplanche , Sandrine Péron , Pierre-Henri Commere , Alan Diot
Rendez-vous scientifique annuel d’Op+lait Réunion glande Mammaire lait, Galactinov, Réseau Oplait-Galctinov, Oct 2023, Québec (online), Canada
Communication dans un congrès hal-04251786v1
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Inflammasome activation and an involvement of Caspase-1 in a bacterial clearance during S. aureus infection.

Elma Lima Leite , Aurélie Nicolas , Arthur Gautron , Martine Deplanche , Jordane Ossemond
Bactinflan, Lia Bactinflam, INRAE STLO, Jun 2022, Webinar, France
Communication dans un congrès hal-03690660v1

Exfoliative toxin E, a new Staphylococcus aureus virulence factor with host-specific activity

I. Imanishi , Aurélie Nicolas , A.C. B. Caetano , Thiago Luiz de Paula Castro , Natayme Rocha Tartaglia
Microbes, 15e Congrès National de la SFM, Sep 2019, Paris, France
Communication dans un congrès hal-02306146v1
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Inflammasomes involvement in Staphylococcus aureus infection of human osteoblast-like cells MG-63

Elma Lima Leite , Arthur Gautron , Martine Deplanche , Aurélie Nicolas , David Gilot
JAS DSA 2018 Journées d'animation scientifique du département Santé Animale, Oct 2018, Chapelle sur Erdre, France
Communication dans un congrès hal-01889269v1
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Unleashing the power of inflammasomes and trained immunity: promising strategies in the fight against Staphylococcus aureus infection

Emmanuel Chaumond , Elma Lima Leite , Nathalie Daniel , Sandrine Peron , Yann Le Gouar
https://immunologisk-selskab.dk/calendar/lofoten-immunology-workshop-2023/. Lofoten Immunology Workshop 2023, Aug 2023, Lofoten Islands, Norway. , 2023
Poster de conférence hal-04195275v1
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Key role of caspase-1 in bacterial clearance during S. aureus infection of osteoblasts-like cells.

Elma Lima Leite , Arthur Gautron , Aurélie Nicolas , Jordane Ossemond , Fillipe L R Do Carmo
SFM Microbes 2021, Sep 2021, Nantes, France. , 2021
Poster de conférence hal-03356389v1
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Inflammasomes involvement in Staphylococcus aureus infection of human osteoblast-like cells MG-63

Elma Lima Leite , Arthur Gautron , Martine Deplanche , Aurélie Nicolas , David Gilot
14.congrès national de la Société Française de Microbiologie (SFM), Oct 2018, Paris, France. , 2018
Poster de conférence hal-01888292v1