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Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins

Brigitt Raux , Yuliia Voitovich , Carine Derviaux , Adrien Lugari , Etienne Rebuffet , et al.
Journal of Medicinal Chemistry, 2016, 59 (4, SI), pp.1634-1641. ⟨10.1021/acs.jmedchem.5b01708⟩
Article dans une revue hal-01439086v1
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Structural Basis for the Interaction between Golgi Reassembly-stacking Protein GRASP55 and Golgin45

Jianfeng Zhao , Bowen Li , Xiaochen Huang , Xavier Morelli , Ning Shi
Journal of Biological Chemistry, 2017, 292 (7), pp.2956 - 2965. ⟨10.1074/jbc.M116.765990⟩
Article dans une revue hal-01787890v1
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Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo

R. Leblanc , R. Kashyap , K. Barral , A.L. Egea‐jimenez , D. Kovalskyy , et al.
Journal of Extracellular Vesicles, 2020, 10 (2), ⟨10.1002/jev2.12039⟩
Article dans une revue hal-03152593v1

Protein-Protein Interaction Inhibition (2P21)-Oriented Chemical Library Accelerates Hit Discovery

Sabine Milhas , Brigitt Raux , Stéphane Betzi , Carine Derviaux , Philippe Roche , et al.
ACS Chemical Biology, 2016, 11 (8), pp.2140-2148. ⟨10.1021/acschembio.6b00286⟩
Article dans une revue hal-01439116v1
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Inhibiting Type VI Secretion System Activity with a Biomimetic Peptide Designed To Target the Baseplate Wedge Complex

Y. Cherrak , I. Filella-Merce , V. Schmidt , D. Byrne , V. Sgoluppi , et al.
mBio, 2021, 12 (4), ⟨10.1128/mbio.01348-21⟩
Article dans une revue pasteur-03429012v1

The type I/type II cytochrome c3 complex: an electron transfer link in the hydrogen-sulfate reduction pathway

L. Pieulle , X. Morelli , P. Gallice , Elizabeth Lojou , P. Barbier , et al.
Journal of Molecular Biology, 2005, 354 (1), pp.73-90
Article dans une revue hal-00335428v1

Accelerating small compounds discovery targeting protein-protein interaction

S. Milhas , S. Betzi , P. Roche , M. Cholay , A. Restouin , et al.
FEBS Journal, 2015, 282 (1, SI), pp.134
Article dans une revue hal-01439038v1
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Fragment-based drug design targeting syntenin PDZ2 domain involved in exosomal release and tumour spread

Manon Garcia , Laurent Hoffer , Raphaël Leblanc , Fatiha Benmansour , Mikael Feracci , et al.
European Journal of Medicinal Chemistry, 2021, 223, pp.113601. ⟨10.1016/j.ejmech.2021.113601⟩
Article dans une revue hal-03379016v1

Structural and genetic analyses reveal a key role in prophage excision for the Torl response regulator inhibitor

L. El Antak , M. Ansaldi , F. Guerlesquin , V. Méjean , X. Morelli
Biological Chemistry, 2005, 280(44), pp.36802-36808
Article dans une revue hal-00067853v1

Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes

Mickaël Bouvet , Adrien Lugari , Clara C. Posthuma , Jessika C. Zevenhoven , Stéphanie Bernard , et al.
Journal of Biological Chemistry, 2014, 289 (37), pp.25783-25796. ⟨10.1074/jbc.M114.577353⟩
Article dans une revue hal-01910944v1

Editorial. Protein-Protein Interaction Analysis and Modulation.

Francoise Ochsenbein , Xavier Morelli , Chandra Verma
Progress in Biophysics and Molecular Biology, 2015, 119 (1), pp.1. ⟨10.1016/j.pbiomolbio.2015.08.019⟩
Article dans une revue hal-02400260v1