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Nuclear Magnetic Resonance Spectroscopy Insights into Tau Structure in Solution: Impact of Post-translational Modifications
Clément Danis
,
Elian Dupré
,
Xavier Hanoulle
,
Isabelle Landrieu
,
Alessia Lasorsa
,
et al.
Chapitre d'ouvrage
hal-02506938v1
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Single Domain Antibody Fragments as New Tools for the Detection of Neuronal Tau Protein in Cells and in Mice Studies
Elian Dupré
,
Clément Danis
,
Alexis Arrial
,
Xavier Hanoulle
,
Mégane Homa
,
et al.
Article dans une revue
hal-02337161v1
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X-ray structure of alisporivir in complex with cyclophilin A at 1.5 Å resolution
Marie Dujardin
,
Julie Bouckaert
,
Prakash Rucktooa
,
Xavier Hanoulle
Acta crystallographica Section F : Structural biology communications [2014-..], 2018, 74 (9), pp.583 - 592. ⟨10.1107/S2053230X18010415⟩
Article dans une revue
hal-01925054v1
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Hepatitis E Virus RNA‐Dependent RNA Polymerase is Involved in RNA Replication and Infectious Particle Production
Noémie Oechslin
,
Nathalie da Silva
,
Dagmara Szkolnicka
,
François‐xavier Cantrelle
,
Xavier Hanoulle
,
et al.
Article dans une revue
hal-03326608v1
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Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening
Léo Faion
,
Kamel Djaout
,
Rosangela Frita
,
Catalin Pintiala
,
Francois-Xavier Cantrelle
,
et al.
Article dans une revue
hal-02988077v1
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Interaction study between HCV NS5A-D2 and NS5B using 19F NMR
Marie Dujardin
,
François-Xavier Cantrelle
,
Guy Lippens
,
Xavier Hanoulle
Article dans une revue
hal-01886452v1
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NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B
Luiza Bessa
,
Hélène Launay
,
Marie Dujardin
,
Xavier Cantrelle
,
Guy Lippens
,
et al.
Article dans une revue
hal-01620117v1
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Tau aggregation in Alzheimer's disease : what role for phosphorylation ?
Guy Lippens
,
Alain Sillen
,
Isabelle Landrieu
,
Laziza Amniai
,
Nathalie Sibille
,
et al.
Prion, 2007, 1 (1), pp.21-25
Article dans une revue
hal-00161158v1
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DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A.
Lotte Coelmont
,
Xavier Hanoulle
,
Udayan Chatterji
,
Carola Berger
,
Joke Snoeck
,
et al.
Article dans une revue
hal-00586948v1
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Proline Conformation in a Functional Tau Fragment
Puneet Ahuja
,
Xavier Cantrelle
,
Isabelle Huvent
,
Xavier Hanoulle
,
Juan Lopez
,
et al.
Article dans une revue
hal-01389832v1
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Ranking High Affinity Ligands of Low Solubility by NMR Spectroscopy
Isabelle Landrieu
,
Xavier Hanoulle
,
Bernd Fritzinger
,
Dragos Horvath
,
Jean-Michel Wieruszeski
,
et al.
Article dans une revue
hal-00618277v1
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Set-up and screening of a fragment library targeting the 14-3-3 protein interface
Dario Valenti
,
João Filipe Neves
,
Francois-Xavier Cantrelle
,
Stanimira Hristeva
,
Domenico Lentini Santo
,
et al.
Article dans une revue
hal-02353610v1
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Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment
Clément Danis
,
Elian Dupré
,
Orgeta Zejneli
,
Raphaëlle Caillierez
,
Alexis Arrial
,
et al.
2021
Pré-publication, Document de travail
hal-03428993v1
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Backbone chemical shift assignments of human 14-3-3σ
João Filipe Neves
,
Isabelle Landrieu
,
Hamida Merzougui
,
Emmanuelle Boll
,
Xavier Hanoulle
,
et al.
Article dans une revue
hal-02107858v1
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Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A
Aurélie Badillo
,
Véronique Receveur-Brechot
,
Stéphane Sarrazin
,
François-Xavier Cantrelle
,
Frédéric Delolme
,
et al.
Article dans une revue
hal-01785410v1
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NMR spectroscopy of the main protease of SARS‐CoV‐2 and fragment‐based screening identify three protein hotspots and an antiviral fragment
François-Xavier Cantrelle
,
Emmanuelle Boll
,
Lucile Brier
,
Danai Moschidi
,
Sandrine Belouzard
,
et al.
Article dans une revue
hal-03363607v1
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Structural basis for the non-immunosuppressive character of the cyclosporin A analogue Debio 025.
Isabelle Landrieu
,
Xavier Hanoulle
,
Fanny Bonachera
,
Arnaud Hamel
,
Nathalie Sibille
,
et al.
Article dans une revue
hal-00508817v1
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Domain 3 of NS5A protein from the hepatitis C virus has intrinsic {alpha}-helical propensity and is a substrate of Cyclophilin A.
Dries Verdegem
,
Aurelie Badillo
,
Jean-Michel Wieruszeski
,
Isabelle Landrieu
,
Arnaud Leroy
,
et al.
Article dans une revue
hal-00586923v1
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Hepatitis C Virus NS5B and Host Cyclophilin A share a common binding site on NS5A.
Claire Rosnoblet
,
Bernd Fritzinger
,
Dominique Legrand
,
Hélène Launay
,
Jean-Michel Wieruszeski
,
et al.
Article dans une revue
hal-00765873v1
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Premier spectromètre RMN 1,2 GHz français : quelles nouvelles possibilités pour l’analyse ?
Fabien Ferrage
,
Pierre Florian
,
Guy Lippens
,
Emmanuel Maes
,
Guido Pintacuda
,
et al.
Réunion des utilisateurs RMN de Bruker France, Nov 2023, Lille, France
Communication dans un congrès
hal-04470791v1
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Phosphorylated full-length Tau interacts with 14-3-3 proteins via two short phosphorylated sequences, each occupying a binding groove of 14-3-3 dimer
João Filipe Neves
,
Olivia Petrvalská
,
Francesco Bosica
,
François‐xavier Cantrelle
,
Hamida Merzougui
,
et al.
Article dans une revue
hal-02989190v1
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Glycan Shielding and Modulation of Hepatitis C Virus Neutralizing Antibodies
Muriel Lavie
,
Xavier Hanoulle
,
Jean Dubuisson
Article dans une revue
hal-02112360v1
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Sandwich-ELISE NMR: reducing the sample volume of NMR samples.
Jean-Michel Wieruszeski
,
Bernd Fritzinger
,
Xavier Hanoulle
,
José C Martins
,
Guy Lippens
Article dans une revue
istex
hal-00293593v1
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Selective backbone labelling of ILV methyl labelled proteins.
Nathalie Sibille
,
Xavier Hanoulle
,
Fanny Bonachera
,
Dries Verdegem
,
Isabelle Landrieu
,
et al.
Article dans une revue
istex
hal-00373458v1
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NMR and circular dichroism data for domain 2 of the HCV NS5A protein phosphorylated by the Casein Kinase II
Luiza Bessa
,
Robert Schneider
,
Xavier Hanoulle
Article dans une revue
hal-02354950v1
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Identification of a Potential Inhibitor of the FIV p24 Capsid Protein and Characterization of Its Binding Site
Mathieu Long
,
François-Xavier Cantrelle
,
Xavier Robert
,
Emmanuelle Boll
,
Natalia Sierra
,
et al.
Article dans une revue
hal-03280829v1
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Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria.
Xavier Hanoulle
,
Jean-Michel Wieruszeski
,
Pierre Rousselot-Pailley
,
Isabelle Landrieu
,
Camille Locht
,
et al.
Article dans une revue
hal-00103724v1
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Hepatitis C virus NS5A protein is a substrate for the Peptidyl-Prolyl cis/trans isomerase activity of Cyclophilins A and B.
Xavier Hanoulle
,
Aurélie Badillo
,
Jean-Michel Wieruszeski
,
Dries Verdegem
,
Isabelle Landrieu
,
et al.
Article dans une revue
hal-00373457v1
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Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation.
Caroline Smet-Nocca
,
Malgorzata Broncel
,
Jean-Michel Wieruszeski
,
Caroline Tokarski
,
Xavier Hanoulle
,
et al.
Article dans une revue
hal-00586849v1
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Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication
Marie Dujardin
,
Vanesa Madan
,
Neha S Gandhi
,
François-Xavier Cantrelle
,
Hélène Launay
,
et al.
Article dans une revue
hal-02998113v1
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