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Design and synthesis of Epicocconone-DNA binder hybrids : Analysing the DNA-Protein interaction

Stéphane Leleu , Xavier Franck , Romain Mougeot , Florence Mahuteau-Betzer , Marie-Paule Teulade-Fichou
French-Japanese Symposium of Medicinal and Fine Chemistry (26, 2017), Sep 2017, Strasbourg, France
Poster de conférence hal-02370800v1

Synthesis and antibacterial activities of cadiolides A, B and C and analogues

Agathe Boulangé , Javier Parraga , Abraham Galan , Nuria Cabedo , Stéphane Leleu , et al.
Bioorganic and Medicinal Chemistry, 2015, 23 (13), pp.3618-3628. ⟨10.1016/j.bmc.2015.04.010⟩
Article dans une revue hal-01150293v1

Development of miniaturized fluorescence-based device for mycotoxin detection

Dorra Gargouri , Abdelaaziz Ouahrouch , Alexandre Haefele , Julien Vieillard , Xavier Franck , et al.
Rencontres en chimie organique biologique (RECOB, 17, 2018), Mar 2018, Aussois, France
Poster de conférence hal-02556310v1

Synthesis of fluorescent or bioactive azaphilones

Xavier Franck
Séminaire international, Osaka Prefecture University, May 2019, Osaka, Japan
Communication dans un congrès hal-02404264v1

Synthesis of fluorescent or bioactive azaphilones

Xavier Franck
Séminaire international, Osaka University, May 2019, Osaka, Japan
Communication dans un congrès hal-02404267v1

Synthesis of fluorescent or bioactive azaphilones

Xavier Franck
Séminaire international, Universidade de Aveiro, Sep 2019, Aveiro, Portugal
Communication dans un congrès hal-02404274v1

Total synthesis of chaetoviridin A

Mehdi Makrerougras , Cyrille Sabot , Franck Xavier
Anglo-Norman colloquium on organic chemistry (ANORCQ, 13, 2016), Apr 2016, Rouen, France
Poster de conférence hal-02370675v1

Direct Transformation Of Amino Acids Into Diazirines And 15N2-Diazirines And Their Application As Hyperpolarized Markers

Thomas Glachet , Hamid Marzag , Nathalie Saraiva Rosa , Johannes Colell , Guannan Zhang , et al.
European symposium on organic chemistry (ESOC, 21, 2019), Jul 2019, Vienne, Austria
Poster de conférence hal-02378326v1

A Straightforward Synthesis of N-Substituted Ureas from Primary Amides

Nathalie Saraiva Rosa , Thomas Glachet , Quentin Ibert , Jean-François Lohier , Xavier Franck , et al.
Synthesis: Journal of Synthetic Organic Chemistry, 2020, 52 (14), pp.2099-2105. ⟨10.1055/s-0040-1707103⟩
Article dans une revue hal-02569464v1

A Short Diastereoselective Total Synthesis of (±)-Vibralactone

A.J. Leeder , R.J. Heap , L.J. Brown , Xavier Franck , R.C.D. Brown
Organic Letters, 2016, 18 (23), pp.5971-5973. ⟨10.1021/acs.orglett.6b03007⟩
Article dans une revue hal-02046220v1
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Synthesis and biological studies of "Polycerasoidol" and "trans-δ-Tocotrienolic acid" derivatives as PPARα and/or PPARγ agonists

Laura Vila , Nuria Cabedo , Carlos Villarroel-Vicente , Ainhoa García , Álvaro Bernabeu , et al.
Bioorganic and Medicinal Chemistry, 2022, 53, pp.116532. ⟨10.1016/j.bmc.2021.116532⟩
Article dans une revue hal-03463394v1

Synthesis of benzopyran derivatives as PPARα and/ or PPARγ activators

Almudena Bermejo , Isabel Barrachina , Noureddine El Aouad , Xavier Franck , Nadia Chahboune , et al.
Bioorganic and Medicinal Chemistry Letters, 2019, 27 (24), pp.115162. ⟨10.1016/j.bmc.2019.115162⟩
Article dans une revue hal-02347291v1

Design and synthesis of epicocconone analogues as polyfunctionnal fluorescent probes for protein labeling

Samuel Oger , Stéphane Leleu , Franck Xavier
Rencontres en chimie organique biologique (RECOB, 16, 2016), Mar 2016, Aussois, France
Poster de conférence hal-02370690v1

Recent progress in the synthesis of azaphilones and analogues

Franck Xavier
International Symposium on catalysis and specialty chemicals, Sep 2018, Tlemcen, Algeria
Communication dans un congrès hal-02354991v1

Petite cueillette d´azaphilones fluorescentes ou bioactives

Xavier Franck
Séminaire national, Institut de chimie des substances naturelles (ICSN, UPR 2301), Nov 2018, Gif-sur-Yvette, France
Communication dans un congrès hal-02395804v1

Diazirine 14N/15N isotopomers: chirality and hyperpolarization

Thomas Glachet , Johannes Colell , Nathalie Saraiva Rosa , Guannan Zhang , Xavier Franck , et al.
International Symposium on Chirality (31, 2019), Jul 2019, Bordeaux, France
Poster de conférence hal-02378318v1

Nouvelle voie de synthèse de diazirines enrichies ou non en azote-15

Vincent Reboul , Thomas Glachet , Hamid Marzag , Franck Xavier
France, N° de brevet: 1860507. 2018
Brevet hal-01926275v1

Iodonitrene in Action: Direct Transformation of Amino Acids into Terminal Diazirines and 15 N 2 -Diazirines and Their Application as Hyperpolarized Markers

Thomas Glachet , Hamid Marzag , Nathalie Saraiva Rosa , Johannes Colell , Guannan Zhang , et al.
Journal of the American Chemical Society, 2019, 141 (34), pp.13689-13696. ⟨10.1021/jacs.9b07035⟩
Article dans une revue hal-02276187v1
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Convergent and Practical Synthesis of Fluorescent Triphenylamine Derivatives and Their Localization in Living Cells

Romain Mougeot , Samuel Oger , Marie Auvray , Thibault Gallavardin , Stéphane Leleu , et al.
European Journal of Organic Chemistry, 2022, 2, ⟨10.1002/ejoc.202101397⟩
Article dans une revue hal-03487097v1

Characterization of fluorescent synthetic epicocconone-based dye through advanced light microscopies for live cell imaging applications

Damien Schapman , Caroline Perraudeau , Magalie Bénard , Thibault Gallavardin , Agathe Boulangé , et al.
Dyes and Pigments, 2017, 141, pp.394-405. ⟨10.1016/j.dyepig.2017.02.034⟩
Article dans une revue hal-02046308v1

Late-Stage Sulfoximination: Improved Synthesis of the Anticancer Drug Candidate Atuveciclib

Thomas Glachet , Xavier Franck , Vincent Reboul
Synthesis: Journal of Synthetic Organic Chemistry, 2019, 51 (4), pp.971-975. ⟨10.1055/s-0037-1610316⟩
Article dans une revue hal-01926262v1
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New synthesis and cyclopropanation of α-phenylselanyl α,β-unsaturated ketones with non-stabilized phosphorus ylides

Sébastien Redon , Stéphane Leleu , Xavier Pannecoucke , Xavier Franck , Francis Outurquin
Tetrahedron, 2008, 64 (39), pp.9293-9304. ⟨10.1016/j.tet.2008.07.025⟩
Article dans une revue hal-01668236v1

Development of miniaturized fluorescence-based device for mycotoxin detection

Dorra Gargouri , Abdelaaziz Ouahrouch , Alexandre Haefele , Julien Vieillard , Xavier Franck , et al.
Journée de l’Ecole doctorale normande de chimie (JEDNC, 2017), Jun 2017, Rouen, France
Poster de conférence hal-02556306v1

New pluses in carbanion chemistry

Jacques Maddaluno , Michaël de Paolis , Xavier Franck , Dominique Cahard
Comptes Rendus Chimie , 2017, 20 (6), pp.593-594. ⟨10.1016/j.crci.2017.05.002⟩
Article dans une revue hal-02024981v1

Epicocconone-Hemicyanine Hybrids: Near Infrared Fluorophores for Protein Staining and Cell Imaging

Peter Karuso , Wendy Loa kum cheung , Philippe Peixoto , Agathe Boulangé , Xavier Franck
Chemistry - A European Journal, 2017, 23 (8), pp.1820-1829. ⟨10.1002/chem.201604698⟩
Article dans une revue hal-03034030v1

Facile and rapid access to linear and truncated microcystin analogues for the implementation of immunoassays.

G. Clavé , C. Ronco , H. Boutal , N. Kreich , H. Volland , et al.
Organic & Biomolecular Chemistry, 2010, 8 (3), pp.676-690. ⟨10.1039/b920193a⟩
Article dans une revue istex hal-00991885v1

Regioselective synthesis of azetidines or pyrrolidines by selenuim-induced cyclization of secondary homoallylic amines

Xavier Franck , Stéphane Leleu , Francis Outurquin
Tetrahedron Letters, 2010, 51 (33), pp.4437-4440. ⟨10.1016/j.tetlet.2010.06.087⟩
Article dans une revue istex hal-01019033v1
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Synthesis of 2-Prenylated Alkoxylated Benzopyrans by Horner-Wadsworth-Emmons olefination with PPARα/γ Agonist Activity

Ainhoa García , Laura Vila , Paloma Marín , Álvaro Bernabeu , Carlos Villarroel-Vicente , et al.
ACS Medicinal Chemistry Letters, 2021, ⟨10.1021/acsmedchemlett.1c00400⟩
Article dans une revue hal-03373981v1

Electronic excitations in epicocconone analogues: TDDFT methodological assessment guided by experiment.

Olga A. Syzgantseva , Vincent Tognetti , Laurent Joubert , Agathe Boulangé , Philippe A. Peixoto , et al.
Journal of Physical Chemistry A, 2012, 116 (33), pp.8634-8643. ⟨10.1021/jp305269y⟩
Article dans une revue hal-00996386v1

Synthèse d'azaphilones fluorescentes ou bioactives

Xavier Franck
Séminaire national, Institut des sciences moléculaires (ISM, UMR5255), Dec 2018, Bordeaux, France
Communication dans un congrès hal-02393902v1