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Researcher identifiers

Number of documents

40

Wassim El Nemer


Journal articles32 documents

  • Sophie Ramadier, Anne Chalumeau, Tristan Felix, Nadia Othman, Sherazade Aknoun, et al.. Combination of lentiviral and genome editing technologies for the treatment of sickle cell disease. Molecular Therapy, Cell Press, 2022, 30 (1), pp.145-163. ⟨10.1016/j.ymthe.2021.08.019⟩. ⟨hal-03531070⟩
  • Ralfs Buks, Tracy Dagher, Maria Rotordam, David Monedero Alonso, Sylvie Cochet, et al.. Altered Ca2+ Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis. Cells, MDPI, 2022, 11 (1), pp.49. ⟨10.3390/cells11010049⟩. ⟨hal-03523607⟩
  • Laurent Pérès, David Monedero Alonso, Morgane Nudel, Martin Figeac, Judith Bruge, et al.. Characterisation of Asp669Tyr Piezo1 cation channel activity in red blood cells: an unexpected phenotype. British Journal of Haematology, Wiley, 2021, ⟨10.1111/bjh.17467⟩. ⟨hal-03242645⟩
  • Ralfs Buks, Mégane Brusson, Sylvie Cochet, Tatiana Galochkina, Bruno Cassinat, et al.. ABCG2 Is Overexpressed on Red Blood Cells in Ph-Negative Myeloproliferative Neoplasms and Potentiates Ruxolitinib-Induced Apoptosis. International Journal of Molecular Sciences, MDPI, 2021, 22 (7), pp.3530. ⟨10.3390/ijms22073530⟩. ⟨hal-03531056⟩
  • Jue Wang, Laura Hertz, Sandra Ruppenthal, Wassim El Nemer, Philippe Connes, et al.. Lysophosphatidic Acid-Activated Calcium Signaling Is Elevated in Red Cells from Sickle Cell Disease Patients. Cells, MDPI, 2021, 10 (2), pp.456. ⟨10.3390/cells10020456⟩. ⟨hal-03531054⟩
  • Wassim El Nemer, Auria Godard, Sara El Hoss. Ineffective erythropoiesis in sickle cell disease: new insights and future implications. Current Opinion in Hematology, Lippincott, Williams & Wilkins, 2021, 28 (3), pp.171-176. ⟨10.1097/MOH.0000000000000642⟩. ⟨hal-03291949⟩
  • Leslie Weber, Giacomo Frati, Tristan Felix, Giulia Hardouin, Antonio Casini, et al.. Editing a y-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype. Science Advances , American Association for the Advancement of Science (AAAS), 2020, 6 (7), pp.eaay9392. ⟨10.1126/sciadv.aay9392⟩. ⟨mnhn-03100446⟩
  • Leslie Weber, Giacomo Frati, Tristan Felix, Giulia Hardouin, Antonio Casini, et al.. Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype. Science Advances , American Association for the Advancement of Science (AAAS), 2020, 6 (7), pp.eaay9392. ⟨10.1126/sciadv.aay9392⟩. ⟨mnhn-03099960⟩
  • Tieying Xu, Maria Lizarralde-Iragorri, Jean Roman, Rasta Ghasemi, Jean-Pierre Lefevre, et al.. Characterization of red blood cell microcirculatory parameters using a bioimpedance microfluidic device. Scientific Reports, Nature Publishing Group, 2020, ⟨10.1038/s41598-020-66693-4⟩. ⟨hal-02872830⟩
  • Yohann Garnier, Séverine Ferdinand, Marie Garnier, Kizzy-Clara Cita, Régine Hierso, et al.. Plasma microparticles of sickle patients during crisis or taking hydroxyurea modify endothelium inflammatory properties. Blood, American Society of Hematology, 2020, 136 (2), pp.247-256. ⟨10.1182/blood.2020004853⟩. ⟨hal-03091322⟩
  • Maria Alejandra Lizarralde-Iragorri, Sophie Lefevre, Sylvie Cochet, Sara El Hoss, Valentine Brousse, et al.. Oxidative stress activates red cell adhesion to laminin in sickle cell disease. Haematologica, Ferrata Storti Foundation, In press, pp.haematol.2020.261586. ⟨10.3324/haematol.2020.261586⟩. ⟨hal-02929195⟩
  • Anna Guadall, Sylvie Cochet, Olivier Renaud, Yves Colin, Caroline Le van Kim, et al.. Dimerization and phosphorylation of Lutheran/basal cell adhesion molecule are critical for its function in cell migration on laminin. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2019, 294 (41), pp.14911-14921. ⟨10.1074/jbc.RA119.007521⟩. ⟨hal-02416861⟩
  • Pedro Moura, Maria Lizarralde Iragorri, Olivier Français, Bruno Le Pioufle, Johannes Dobbe, et al.. Reticulocyte and red blood cell deformation triggers specific phosphorylation events. Blood Advances, The American Society of Hematology, 2019, 3 (17), pp.2653-2663. ⟨10.1182/bloodadvances.2019000545⟩. ⟨hal-02289553⟩
  • Maria Alejandra Lizarralde Iragorri, Sara El Hoss,, Valentine Brousse, Sophie Lefevre, Michael Dussiot, et al.. A microfluidic approach to study the effect of mechanical stress on erythrocytes in sickle cell disease. Lab on a Chip, Royal Society of Chemistry, 2018, 18 (19), pp.2975-2984. ⟨10.1039/C8LC00637G⟩. ⟨hal-01875109⟩
  • Slim Azouzi, Marc Romana, Nobuto Arashiki, Yuichi Takakuwa, Wassim El Nemer, et al.. Band 3 phosphorylation induces irreversible alterations of stored red blood cells. American Journal of Hematology, Wiley, 2018, 93 (5), pp.E110 - E112. ⟨10.1002/ajh.25044⟩. ⟨hal-01825593⟩
  • Megane Brusson, Maria de Grandis, Sylvie Cochet, Sylvain Bigot, Mickael Marin, et al.. Impact of hydroxycarbamide and interferon-alpha on red cell adhesion and membrane protein expression in polycythemia vera. Haematologica, Ferrata Storti Foundation, 2018, 103 (6), pp.972-981. ⟨10.3324/haematol.2017.182303⟩. ⟨hal-02117996⟩
  • Emilie-Fleur Gautier, Marjorie Leduc, Sylvie Cochet, Karine Bailly, Catherine Lacombe, et al.. Absolute proteome quantification of highly purified populations of circulating reticulocytes and mature erythrocytes. Blood Advances, The American Society of Hematology, 2018, 2 (20), pp.2646-2657. ⟨10.1182/bloodadvances.2018023515⟩. ⟨hal-02365675⟩
  • Valentine Brousse, Sara El Hoss, Naim Bouazza, Cécile Arnaud, Françoise Bernaudin, et al.. Prognostic factors of disease severity in infants with sickle cell anemia: A comprehensive longitudinal cohort study. American Journal of Hematology, Wiley, 2018, 93 (11), pp.1411-1419. ⟨10.1002/ajh.25260⟩. ⟨hal-02416879⟩
  • C. Antoniani, V. Meneghini, A. Lattanzi, T. Felix, O. Romano, et al.. Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human beta-globin locus. Blood, American Society of Hematology, 2018, 131, pp.1960-1973. ⟨10.1182/blood-2017-10-811505⟩. ⟨hal-02880783⟩
  • L. Weber, V. Poletti, E. Magrin, C. Antoniani, S. Martin, et al.. An Optimized Lentiviral Vector Efficiently Corrects the Human Sickle Cell Disease Phenotype. Mol Ther Methods Clin Dev, 2018, 10, pp.268-280. ⟨10.1016/j.omtm.2018.07.012⟩. ⟨hal-02880821⟩
  • Annalisa Lattanzi, Vasco Meneghini, Giulia Pavani, Fatima Amor, Sophie Ramadier, et al.. The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension. Cell, Elsevier, 2017, 169 (4), pp.693-707.e14. ⟨10.1016/j.cell.2017.04.013⟩. ⟨hal-03588462⟩
  • Jean-Antoine Ribeil, Salima Hacein-Bey-Abina, Emmanuel Payen, Alessandra Magnani, Michaela Semeraro, et al.. Gene Therapy in a Patient with Sickle Cell Disease. New England Journal of Medicine, Massachusetts Medical Society, 2017, 376 (9), pp.848 - 855. ⟨10.1056/NEJMoa1609677⟩. ⟨inserm-01834781⟩
  • Barbara Sandor, Mickaël Marin, Claudine Lapouméroulie, Miklos Rabaï, Sophie Lefevre, et al.. Effects of Poloxamer 188 on red blood cell membrane properties in sickle cell anaemia. British Journal of Haematology, Wiley, 2016, 173 (1), pp.145 - 149. ⟨10.1111/bjh.13937⟩. ⟨hal-01881668⟩
  • Julien Duez, John P. Holleran, Papa Alioune Ndour, Sasdekumar Loganathan, Pascal Amireault, et al.. Splenic retention of Plasmodium falciparum gametocytes to block the transmission of malaria. Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2015, pp.AAC.05030-14. ⟨10.1128/AAC.05030-14⟩. ⟨hal-01158996⟩
  • Julien Picot, Papa Alioune Ndour, Sophie D. Lefevre, Wassim El Nemer, Harvey Tawfik, et al.. A biomimetic microfluidic chip to study the circulation and mechanical retention of red blood cells in the spleen. American Journal of Hematology, Wiley, 2015, ⟨10.1002/ajh.23941⟩. ⟨hal-01113050⟩
  • Maria de Grandis, Marie Cambot, Marie-Paule Wautier, Bruno Cassinat, Christine Chomienne, et al.. JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway.: JAK2V617F activates Lu/BCAM through Rap1/Akt. Blood, American Society of Hematology, 2013, 121 (4), pp.658-65. ⟨10.1182/blood-2012-07-440487⟩. ⟨inserm-00821109⟩
  • L. Kobar, F. Yates, N. Oudrhiri, A. Francina, L. Kiger, et al.. Human induced pluripotent stem cells can reach complete terminal maturation In vivo and in vitro evidence in the erythropoietic differentiation model. Haematologica, Ferrata Storti Foundation, 2012, 97 (12), pp.1795-1803. ⟨10.3324/haematol.2011.055566⟩. ⟨hal-02920223⟩
  • Emmanuel Collec, Marie-Christine Lecomte, Wassim El-Nemer, Yves Colin, Caroline Le van Kim. Novel role for the Lu/BCAM-spectrin interaction in actin cytoskeleton reorganization. Biochemical Journal, Portland Press, 2011, 436 (3), pp.699-708. ⟨10.1042/BJ20101717⟩. ⟨hal-00596275⟩
  • Pablo Bartolucci, Vicky Chaar, Julien Picot, Dora Bachir, Anoosha Habibi, et al.. Decreased sickle red blood cell adhesion to laminin by hydroxyurea is associated with inhibition of Lu/BCAM protein phosphorylation.: HU inhibits Lu/BCAM phosphorylation in sickle RBCs. Blood, American Society of Hematology, 2010, 116 (12), pp.2152-9. ⟨10.1182/blood-2009-12-257444⟩. ⟨inserm-00821117⟩
  • Vicky Chaar, Julien Picot, Olivier Renaud, Pablo Bartolucci, Ruben Nzouakou, et al.. Aggregation of mononuclear and red blood cells through an {alpha}4{beta}1-Lu/basal cell adhesion molecule interaction in sickle cell disease.: Mononuclear and sickle red blood cell interactions. Haematologica, Ferrata Storti Foundation, 2010, 95 (11), pp.1841-8. ⟨10.3324/haematol.2010.026294⟩. ⟨inserm-00821120⟩
  • M. André, Jean-Pierre Le Caer, C. Greco, S. Planchon, W. El Nemer, et al.. Proteomic analysis of the tetraspanin web using LC-ESI-MS/MS and MALDI-FTICR-MS.. Proteomics, Wiley-VCH Verlag, 2006, 6 (5), pp.1437-1449. ⟨10.1002/pmic.200500180⟩. ⟨hal-00904619⟩
  • Emmanuel Collec, Wassim El Nemer, Emilie Gauthier, Pierre Gane, Marie-Christine Lecomte, et al.. Ubc9 interacts with Lu/BCAM adhesion glycoproteins and regulates their stability at the membrane of polarized MDCK cells. Biochemical Journal, Portland Press, 2006, 402 (2), pp.311-319. ⟨10.1042/BJ20060861⟩. ⟨hal-00478614⟩

Conference papers8 documents

  • Xu Tieying, Maria Lizarralde Iragorri, Jean Roman, Emile Martincic, Valentine Brousse, et al.. Different miniaturization systems of electrical biosensing and data acquisition during biological cell transiting within vessel size microchannel. MicroTAS 2021, Oct 2021, Palm Springs, United States. ⟨hal-03653515⟩
  • Tieying Xu, Maria Lizarralde-Iragorri, Jean Roman, Emile Martincic, Valentine Brousse, et al.. A microfluidic device to statistically determine the distribution of sickle red cell subpopulations using bioimpedance. Transducers, 2021, on-line, France. ⟨hal-03260796⟩
  • Xu Tieying, Maria Lizarralde Iragorri, Jean Roman, Emile Martincic, Valentine Brousse, et al.. Spherocytes flow behaviours in microrestriction, compared by normal red blood cells of different heat treatment levels. MicroTAS 2021, Oct 2021, Palm Springs, United States. ⟨hal-03653511⟩
  • Tieying Xu, Maria Lizarralde-Iragorri, Jean Roman, Emile Martincic, Valentine Brousse, et al.. Electrical Sensing of sickled red blood cells subpopulations in microfluidic device. MicroTAS, Oct 2020, on-line, France. ⟨hal-03078878⟩
  • Xu Tieying, Maria Lizarralde, Jean Roman, Wassim El Nemer, Bruno Le Pioufle, et al.. Electrical Detection of the Mechanical Alteration of Sickling Red Blood Cells within a Microfluidic Capillary Network. MicroTAS, Oct 2019, Basel, Switzerland. ⟨hal-02387976⟩
  • Xu Tieying, Maria Lizarralde, Wassim El Nemer, Bruno Le Pioufle, Olivier Français. Microfluidic device using reusable parylen-pdms packaging for the red blood cell transit time analysis in mechanical constrictions, using impedance measurement. MicroTAS, Nov 2018, Kaohsiung, Taiwan. ⟨hal-01972640⟩
  • Tieying Xu,, Maria Lizarralde,, Wassim El Nemer, Bruno Le Pioufle, Olivier Français. Monitoring Biological Cell Flow within a Mimicking Capillary Device with Impedance Measurement. Eurosensors, Sep 2017, Paris, France. pp.3 - 6, ⟨10.3390/proceedings1040517⟩. ⟨hal-01592142⟩
  • Wassim El Nemer, Papa Alioune Ndour, Sophie D. Lefevre, Harvey Tawfik, Julien Picot, et al.. A microfluidic device to study red blood cell deformability. 4th European Conference on Microfluidics, Dec 2014, Limerick, Ireland. ⟨hal-01113061⟩