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Adenomatous Polyposis Coli Defines Treg Differentiation and Anti-inflammatory Function through Microtubule-Mediated NFAT Localization

Sonia Agüera-Gonzalez , Oliver T. Burton , Elena Vázquez-Chávez , Céline Cuche , Floriane Herit , et al.
Cell Reports, 2017, 21 (1), pp.181-194. ⟨10.1016/j.celrep.2017.09.020⟩
Article dans une revue hal-01614654v1

Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse.

Rémi Lasserre , Stephanie Charrin , Céline Cuche , Anne Danckaert , Maria-Isabel Thoulouze , et al.
EMBO Journal, 2010, 29 (14), pp.2301-14. ⟨10.1038/emboj.2010.127⟩
Article dans une revue pasteur-00593159v1

CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens.

Maria-Elena Marquez , Wilfried Ellmeier , Vanesa Sanchez-Guajardo , Antonio A Freitas , Oreste Acuto , et al.
Journal of Immunology, 2005, 175 (11), pp.7388-97. ⟨10.4049/jimmunol.175.11.7388⟩
Article dans une revue hal-00138110v1
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Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation.

Rémi Lasserre , Céline Cuche , Ronnie Blecher-Gonen , Evgeny Libman , Elise Biquand , et al.
Journal of Cell Biology, 2011, 195 (5), epub ahead of print. ⟨10.1083/jcb.201103105⟩
Article dans une revue pasteur-00646203v1
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HIV-1 Nef Hijacks Lck and Rac1 Endosomal Traffic To Dually Modulate Signaling-Mediated and Actin Cytoskeleton–Mediated T Cell Functions

Iratxe del Río-Iñiguez , Elena Vázquez-Chávez , Céline Cuche , Vincenzo Di Bartolo , Jérôme Bouchet , et al.
Journal of Immunology, 2018, 201 (9), pp.2624 - 2640. ⟨10.4049/jimmunol.1800372⟩
Article dans une revue pasteur-01907920v1

T-cell receptor-induced phosphorylation of the zeta chain is efficiently promoted by ZAP-70 but not Syk

M. Steinberg , O. Adjali , L. Swainson , P. Merida , V. Di Bartolo , et al.
Blood, 2004, 104 (3), pp.760--7. ⟨10.1182/blood-2003-12-4314⟩
Article dans une revue hal-02262389v1

Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events.

Sheerazed Boulkroun , Laure Guenin-Macé , Maria-Isabel Thoulouze , Marc Monot , Anaïs Merckx , et al.
Journal of Immunology, 2010, 184 (3), pp.1436-44. ⟨10.4049/jimmunol.0902854⟩
Article dans une revue pasteur-00594632v1

Large-scale screening for genes involved in T-cell signaling: do we know all the players now?

Vincenzo Di Bartolo , Oreste Acuto
Trends in Immunology, 2004, 25 (8), pp.399-402. ⟨10.1016/j.it.2004.06.001⟩
Article dans une revue istex hal-00138114v1
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Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function

Victor H Navas , Céline Cuche , Andres Alcover , Vincenzo Di Bartolo
PLoS ONE, 2017, 12 (1), pp.e0170396. ⟨10.1371/journal.pone.0170396⟩
Article dans une revue hal-01446556v1
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Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation

Jérôme Bouchet , Iratxe del Río-Iñiguez , Rémi Lasserre , Sonia Agüera-Gonzalez , Céline Cuche , et al.
EMBO Journal, 2016, ⟨10.15252/embj.201593274⟩
Article dans une revue pasteur-01370720v1

Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck.

M. Pelosi , V. Di Bartolo , V. Mounier , D. Mège , J. M. Pascussi , et al.
Journal of Biological Chemistry, 1999, 274 (20), pp.14229-37. ⟨10.1074/jbc.274.20.14229⟩
Article dans une revue hal-00138125v1

Tyrosine 319, a newly identified phosphorylation site of ZAP-70, plays a critical role in T cell antigen receptor signaling.

V. Di Bartolo , D. Mège , V. Germain , M. Pelosi , E. Dufour , et al.
Journal of Biological Chemistry, 1999, 274 (10), pp.6285-94. ⟨10.1074/jbc.274.10.6285⟩
Article dans une revue hal-00138130v1

In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern.

Nicolas Blanchard , Vincenzo Di Bartolo , Claire Hivroz
Immunity, 2002, 17 (4), pp.389-99. ⟨10.1016/S1074-7613(02)00421-1⟩
Article dans une revue hal-00138115v1

ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation.

Nathalie Sol-Foulon , Marion Sourisseau , Françoise Porrot , Maria-Isabel Thoulouze , Céline Trouillet , et al.
EMBO Journal, 2007, 26 (2), pp.516-26. ⟨10.1038/sj.emboj.7601509⟩
Article dans une revue pasteur-00292789v1
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A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76.

Vincenzo Di Bartolo , Benjamin Montagne , Mogjiborahman Salek , Britta Jungwirth , Florent Carrette , et al.
Journal of Experimental Medicine, 2007, 204 (3), pp.681-91. ⟨10.1084/jem.20062066⟩
Article dans une revue pasteur-01372621v1

The Shigella flexneri Type Three Secretion System Effector IpgD Inhibits T Cell Migration by Manipulating Host Phosphoinositide Metabolism.

Christoph Konradt , Elisabetta Frigimelica , Katharina Nothelfer , Andrea Puhar , Wilmara Salgado-Pabon , et al.
Cell Host and Microbe, 2011, 9 (4), pp.263-72. ⟨10.1016/j.chom.2011.03.010⟩
Article dans une revue pasteur-00594631v1

Cell Biology of T Cell Receptor Expression and Regulation

Andres Alcover , Balbino Alarcón , Vincenzo Di Bartolo
Annual Review of Immunology, 2018, 36 (1), pp.103-125. ⟨10.1146/annurev-immunol-042617-053429⟩
Article dans une revue pasteur-03028889v1
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Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids

Valentin Bonnet , Erik Maikranz , Marianne Madec , Nadia Vertti-Quintero , Céline Cuche , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (11), pp.e2316500121. ⟨10.1073/pnas.2316500121⟩
Article dans une revue pasteur-04500002v1

Tailoring T-cell receptor signals by proximal negative feedback mechanisms.

Oreste Acuto , Vincenzo Di Bartolo , Frédérique Michel
Nature Reviews Immunology, 2008, 8 (9), pp.699-712. ⟨10.1038/nri2397⟩
Article dans une revue istex pasteur-00369557v1
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Coordinating Cytoskeleton and Molecular Traffic in T Cell Migration, Activation, and Effector Functions

Marta Mastrogiovanni , Marie Juzans , Andrés Alcover , Vincenzo Di Bartolo
Frontiers in Cell and Developmental Biology, 2020, 8, pp.591348. ⟨10.3389/fcell.2020.591348⟩
Article dans une revue hal-03011461v1

T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase.

A. Magnan , V. Di Bartolo , A. M. Mura , Claudine Boyer , M. Richelme , et al.
Journal of Experimental Medicine, 2001, 194 (4), pp.491-505. ⟨10.1084/jem.194.4.491⟩
Article dans une revue hal-00138121v1
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Adenomatous Polyposis Coli Modulates Actin and Microtubule Cytoskeleton at the Immunological Synapse to Tune CTL Functions

Marie Juzans , Céline Cuche , Thierry Rose , Marta Mastrogiovanni , Pascal Bochet , et al.
ImmunoHorizons , 2020, 4 (6), pp.363-381. ⟨10.4049/immunohorizons.2000044⟩
Article dans une revue pasteur-02975339v1
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Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses

Claudia Demarta-Gatsi , Anna Rivkin , Vincenzo Di Bartolo , Roger Peronet , Shuai Ding , et al.
Cellular Microbiology, 2019, 21 (7), ⟨10.1111/cmi.13021⟩
Article dans une revue hal-02571995v2
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Rab11-FIP3 Regulation of Lck Endosomal Traffic Controls TCR Signal Transduction.

Jérôme Bouchet , Iratxe del Río-Iñiguez , Elena Vázquez-Chávez , Rémi Lasserre , Sonia Agüera-González , et al.
Journal of Immunology, 2017, pp.2967-2978. ⟨10.4049/jimmunol.1600671⟩
Article dans une revue pasteur-01519813v1
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TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70.

Céline Dumont , Nicolas Blanchard , Vincenzo Di Bartolo , Nathalie Lezot , Evelyne Dufour , et al.
Journal of Immunology, 2002, 169, pp.1705-12. ⟨10.4049/jimmunol.169.4.1705⟩
Article dans une revue inserm-00000024v1
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Comparative Anatomy of Phagocytic and immunological Synapses

Florence Niedergang , Vincenzo Di Bartolo , Andrés Alcover
Frontiers in Immunology, 2016, ⟨10.3389/fimmu.2016.00018⟩
Article dans une revue pasteur-01286933v1

Tyrosine 315 determines optimal recruitment of ZAP-70 to the T cell antigen receptor.

Vincenzo Di Bartolo , Marie Malissen , Evelyne Dufour , Emmanuel Sechet , Bernard Malissen , et al.
European Journal of Immunology, 2002, 32 (2), pp.568-75. ⟨10.1002/1521-4141(200202)32:2<568::AID-IMMU568>3.0.CO;2-Q⟩
Article dans une revue hal-00138113v1
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Cell polarity regulators, multifunctional organizers of lymphocyte activation and function

Marta Mastrogiovanni , Vincenzo Di Bartolo , Andrés Alcover
Biomedical journal, 2022, ⟨10.1016/j.bj.2021.10.002⟩
Article dans une revue pasteur-03455203v1
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Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression.

Laure Guenin-Macé , Florent Carrette , François Asperti-Boursin , Agnès Le Bon , Laxmee Caleechurn , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (31), pp.12833-8. ⟨10.1073/pnas.1016496108⟩
Article dans une revue pasteur-00738806v1
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The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration

Marta Mastrogiovanni , Pablo Vargas , Thierry Rose , Céline Cuche , Elric Esposito , et al.
Science Advances , 2022, 8 (15), pp.eabl5942. ⟨10.1126/sciadv.abl5942⟩
Article dans une revue pasteur-03681845v1