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Synthesis and biological evaluation of novel anticancer bivalent colchicine–tubulizine hybrids

Yulia Malysheva , Sébastien Combes , Diane Allegro , Vincent Peyrot , Paul Knochel , et al.
Bioorganic and Medicinal Chemistry, 2012, 20 (14), pp.4271 - 4278. ⟨10.1016/j.bmc.2012.05.072⟩
Article dans une revue istex hal-01749009v1
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Tau antagonizes end-binding protein tracking at microtubule ends through a phosphorylation- dependent mechanism

Sacnicte Ramirez-Rios , Eric Denarier , Elea Prezel , Angélique Vinit , Virginie Stoppin-Mellet , et al.
Molecular Biology of the Cell, 2016, 27 (19), pp.2924-2934. ⟨10.1091/mbc.E16-01-0029)⟩
Article dans une revue hal-01478521v1
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Sequential binding of calcium ions to the B-repeat domain of SdrD from Staphylococcus aureus

Andrei A Roman , François Devred , Vladimir M Lobatchov , Alexander A Makarov , Vincent Peyrot , et al.
Canadian Journal of Microbiology, 2016, 62 (2), pp.123-129. ⟨10.1139/cjm-2015-0580⟩
Article dans une revue hal-01478554v1
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Stathmin Potentiates Vinflunine and Inhibits Paclitaxel Activity

Soazig Malesinski , Philipp O. Tsvetkov , Anna Kruczynski , Vincent Peyrot , François Devred
PLoS ONE, 2015
Article dans une revue hal-01207790v1

Synthesis and complete assignment of the 1H and 13C NMR signals of new acetamido and aminoflavonoid derivatives

Gilles Casano , Maxime Robin , Pascale Barbier , Vincent Peyrot , Robert Faure
Magnetic Resonance in Chemistry, 2010, 48 (9), pp.738 - 744. ⟨10.1002/mrc.2638⟩
Article dans une revue istex hal-01753144v1
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Direct evidence for the interaction of stathmin along the length and the plus end of microtubules in cells

Roqiya Nouar , Gilles Breuzard , Sonia Bastonero , Svetlana Gorokhova , Pascale Barbier , et al.
FASEB Journal, 2016, 30 (9), pp.3202 - 3215. ⟨10.1096/fj.201500125R⟩
Article dans une revue inserm-01472736v1

Hsp90 Oligomers Interacting with the Aha1 Cochaperone: An Outlook for the Hsp90 Chaperone Machineries

Eléonore Lepvrier , Laura Moullintraffort , Michaël Nigen , Renan Goude , Diane Allegro , et al.
Analytical Chemistry, 2015, 87 (14), pp.7043-7051. ⟨10.1021/acs.analchem.5b00051⟩
Article dans une revue hal-01175535v1
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Microtubule and MAPs: thermodynamics of complex formation by AUC, ITC, fluorescence, and NMR.

François Devred , Pascale Barbier , Daniel Lafitte , Isabelle Landrieu , Guy Lippens , et al.
Methods in Cell Biology, 2010, 95, pp.449-480. ⟨10.1016/S0091-679X(10)95023-1⟩
Article dans une revue hal-00508818v1

Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: Synthesis, structure-activity relationship, and action mechanism studies.

Vincent Moret , Younes Laras , Thierry Cresteil , Geneviève Aubert , Dou Q Ping , et al.
European Journal of Medicinal Chemistry, 2008, 44 (2), pp.558-557. ⟨10.1016/j.ejmech.2008.03.042⟩
Article dans une revue istex hal-00294478v1
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Microtubule-Associated Proteins and Tubulin Interaction by Isothermal Titration Calorimetry

Philipp O Tsvetkov , Pascale Barbier , Gilles Breuzard , Vincent Peyrot , François Devred
Methods in Cell Biology, 115, pp.283 - 302, 2013, Microtubules, In Vitro 978-0-12-407757-7. ⟨10.1016/B978-0-12-407757-7.00018-9⟩
Chapitre d'ouvrage hal-01478645v1
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Zinc Induces Temperature-Dependent Reversible Self-Assembly of Tau

Andrei Yu Roman , François Devred , Deborah Byrne , Romain La Rocca , Natalia N Ninkina , et al.
Journal of Molecular Biology, 2018, ⟨10.1016/j.jmb.2018.12.008⟩
Article dans une revue hal-01981683v2

Synthesis and biological evaluation of 4 arylcoumarin analogues as tubulin-targeting antitumor agents

Peggoty Mutai , Gilles Breuzard , Alessandra Pagano , Diane Allegro , Vincent Peyrot , et al.
Bioorganic and Medicinal Chemistry, 2017, 25 (5), pp.1652 - 1665. ⟨10.1016/j.bmc.2017.01.035⟩
Article dans une revue hal-01744155v1

Caulerpenyne binding to tubulin: structural modifications by a non conventional pharmacological agent.

Julien Bourdron , Pascale Barbier , Diane Allegro , Claude Villard , Daniel Lafitte , et al.
Medicinal Chemistry, 2009, 5 (2), pp.182-90
Article dans une revue hal-00678950v1

Molecular mechanisms of Tau binding to microtubules and its role in microtubule dynamics in live cells.

Gilles Breuzard , Pierre Hubert , Roqiya Nouar , Tiphany De Bessa , François Devred , et al.
Journal of Cell Science, 2013, 126 (Pt 13), pp.2810--9. ⟨10.1242/jcs.120832⟩
Article dans une revue hal-01458234v1

New insights into the antibacterial mechanism of action of squalamine

Kamel Alhanout , Soazig Malesinki , Nicolas Vidal , Vincent Peyrot , Jean-Marc Rolain , et al.
Journal of Antimicrobial Chemotherapy, 2010, 65 (8), pp.1688--1693. ⟨10.1093/jac/dkq213⟩
Article dans une revue hal-01460197v1
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Tau Interaction with Tubulin and Microtubules: From Purified Proteins to Cells

Tiphany de Bessa , Gilles Breuzard , Diane Allegro , François Devred , Vincent Peyrot , et al.
Tau Protein, 1523, pp.61-85, 2017, ⟨10.1007/978-1-4939-6598-4_4⟩
Chapitre d'ouvrage hal-01744157v2
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Tau Induces Ring and Microtubule Formation from R-Tubulin Dimers under Nonassembly Conditions

François Devred , Pascale Barbier , Soazig Douillard , Octavio Monasterio , José Manuel Andreu , et al.
Biochemistry, 2004, 43 (32), pp.10520-10531. ⟨10.1021/bi0493160⟩
Article dans une revue hal-01340743v1

New insights into tau–microtubules interaction revealed by isothermal titration calorimetry

Philipp O Tsvetkov , Alexander Makarov , Soazig Malesinski , Vincent Peyrot , François Devred
Biochimie, 2012, 94 (3), pp.916 - 919. ⟨10.1016/j.biochi.2011.09.011⟩
Article dans une revue hal-01749107v1

Apo-Hsp90 coexists in two open conformational states in solution.

Patrick Bron , Emmanuel Giudice , Jean-Paul Rolland , Rubén M Buey , Pascale Barbier , et al.
Biology of the Cell, 2008, 100 (7), pp.413-25. ⟨10.1042/BC20070149⟩
Article dans une revue hal-00290075v1
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Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat.

Caroline Egelé , Pascale Barbier , Pascal Didier , Etienne Piémont , Diane Allegro , et al.
Retrovirology, 2008, 5, pp.62. ⟨10.1186/1742-4690-5-62⟩
Article dans une revue hal-00321631v1

The Indolylcoumarin Coufin Exhibits Potent Activity Against Renal Carcinoma Cells without Affecting Hematopoietic System.

Pierre Champelovier , Pascale Barbier , Etienne Daras , Soazig Douillard , Bertrand Toussaint , et al.
Current Medicinal Chemistry Anticancer Agents, 2014, epub ahead of print. ⟨10.2174/1871520614666140223190829⟩
Article dans une revue hal-01005896v1

FRET and FRAP imaging: Approaches to characterise tau and stathmin interactions with microtubules in cells

Roqiya Nouar , François Devred , Gilles Breuzard , Vincent Peyrot
Biology of the Cell, 2013, 105 (4), pp.149 - 161. ⟨10.1111/boc.201200060⟩
Article dans une revue istex hal-01744472v1

Alzheimer disease specific phosphoepitopes of Tau interfere with assembly of tubulin but not binding to microtubules.

Laziza Amniai , Pascale Barbier , Alain Sillen , Jean-Michel Wieruszeski , Vincent Peyrot , et al.
FASEB Journal, 2009, 23 (4), pp.1146-52. ⟨10.1096/fj.08-121590⟩
Article dans une revue hal-00348164v1

Interactions of long-chain homologues of colchicine with tubulin

Ana Marzo-Mas , Pascale Barbier , Gilles Breuzard , Diane Allegro , Eva Falomir , et al.
European Journal of Medicinal Chemistry, 2017, 126, pp.526 - 535. ⟨10.1016/j.ejmech.2016.11.049⟩
Article dans une revue hal-01744468v1

Tau regulates the microtubule-dependent migration of glioblastoma cells via the Rho-ROCK signaling pathway

Gilles Breuzard , Alessandra Pagano , Sonia Bastonero , Soazig Malesinski , Fabrice Parat , et al.
Journal of Cell Science, 2019, pp.jcs.222851. ⟨10.1242/jcs.222851⟩
Article dans une revue hal-01987458v1
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Stathmin/Op18 is a novel mediator of vinblastine activity

François Devred , Philipp O Tsvetkov , Pascale Barbier , Diane Allegro , Susan Band Horwitz , et al.
FEBS Letters, 2008, 582 (17), pp.2484 - 2488. ⟨10.1016/j.febslet.2008.06.035⟩
Article dans une revue hal-01756897v1
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Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat

Caroline Egelé , Pascal Barbier , Pascal Didier , Etienne Piémont , Diane Allegro , et al.
Retrovirology, 2008, 5, pp.62. ⟨10.1186/1742-4690-5-62⟩
Article dans une revue hal-01480684v1
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Three-dimensional structure of the lithostathine protofibril, a protein involved in Alzheimer's disease.

Catherine Grégoire , Sergio Marco , Jean Thimonier , Laure Duplan , Emmanuelle Laurine , et al.
EMBO Journal, 2001, 20 (13), pp.3313-21. ⟨10.1093/emboj/20.13.3313⟩
Article dans une revue inserm-00144804v1

Biochemical and biophysical characterization of the Mg2+-induced 90-kDa heat shock protein oligomers.

Laura Moullintraffort , Matthieu Bruneaux , Alexis Nazabal , Diane Allegro , Emmanuel Giudice , et al.
Journal of Biological Chemistry, 2010, 285 (20), pp.15100-10. ⟨10.1074/jbc.M109.094698⟩
Article dans une revue hal-00485599v1

Peptide screen identifies a new NADPH oxidase inhibitor: impact on cell migration and invasion

Mohamed Mousslim , Alessandra Pagano , Nicolas Andreotti , Françoise Garrouste , Sylvie Thuault , et al.
European Journal of Pharmacology, 2016, ⟨10.1016/j.ejphar.2016.10.011⟩
Article dans une revue hal-01460690v1