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Enantioselective Organocatalyzed alpha-Sulfanylation of Isoxazolidin-5-ones : an Approach to beta 2,2-Amino Acids

Timothée Cadart , Vincent Levacher , Perrio Stéphane , Jean-François Brière
Journée de l’Ecole doctorale normande de chimie (JEDNC, 2017), Jun 2017, Mont-Saint-Aignan, France
Poster de conférence hal-02299138v1

Organocatalysed decarboxylative protonation process from Meldrum's acid: enantioselective synthesis of isoxazolidinones.

Tony Tite , Mohamad Sabbah , Vincent Levacher , Jean-François Brière
Chemical Communications, 2013, 49 (98), pp.11569-11571. ⟨10.1039/c3cc47695b⟩
Article dans une revue hal-00997428v1
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Ortho-Directed Palladium-Catalyzed Direct C–H Functionalization of 3-Picolinyl- and 3-(2-Cyanoethyl)pyrimidin-4(3H)-ones with Aryl Halides

Sandra Collado Ruiz , Mickaël Muselli , Steven Frippiat , Thierno Mamoudou Diallo , Anissa Mohamed-Cherif , et al.
SYNLETT, 2020, 31 (12), pp.1185-1190. ⟨10.1055/s-0040-1707523⟩
Article dans une revue hal-03033560v1

Development of new redox chemical delivery systems for targeting radiotracers into the brain

A Henry , C Papamicaël , D Patin , F Gourand , L Barré , et al.
Journée de l’Ecole Doctorale Normande de Chimie (JEDNC), Jun 2016, Caen, France
Poster de conférence hal-02386584v1

Preparation of β-Lactams by Mannich-Type Addition of Ethyl(trimethyl­silyl)acetate (ETSA) to N-(2-Hydroxyphenyl)aldimine Sodium Salts

Vincent Gembus , Thomas Poisson , Sylvain Oudeyer , Francis Marsais , Vincent Levacher
SYNLETT, 2009, 2009 (15), pp.2437-2440. ⟨10.1055/s-0029-1217729⟩
Article dans une revue hal-02278770v1

Chiral ammonium aryloxides as nucleophilic organocatalysts : Application to the enantioselective decarboxylative protonation of Meldrum’s acid derivatives

Sylvain Oudeyer , Fabien Legros , Thomas Martzel , Julien Annibaletto , Jean-François Brière , et al.
Journées de chimie organique (JCO, 2019), Oct 2019, Palaiseau, France
Communication dans un congrès hal-02543021v1

Chiral Ammonium Aryloxides: Efficient Multipurpose Basic Organocatalysts

Jérémy Godemert , Sylvain Oudeyer , Vincent Levacher
ChemCatChem, 2016, 8 (1), pp.74-85. ⟨10.1002/cctc.201500616⟩
Article dans une revue istex hal-02046209v1

Organocatalyzed Synthesis of azolidin-5-one derivatives: The Meldrum's acid approach

Etienne Pair , Christophe Berini , Romain Noel , Vincent Levacher , Jean-François Brière
Semaine d'études en chimie organique (SECO, 52, 2015), May 2015, Morzine, France
Communication dans un congrès hal-02378646v1

Meldrum's acid derivatives and chiral ammonium phenoxides : a useful combination for asymmetric synthesis

Fabien Legros , Jean-François Brière , Sylvain Oudeyer , Vincent Levacher
Journée de l’Ecole doctorale normande de chimie (JEDNC, 2016), Jun 2016, Caen, France
Communication dans un congrès hal-02374269v1

Synthesis and orthogonal functionalization of oxazolo[5′,4′:4,5]pyrano[2,3-b]pyridine by intra- and intermolecular Pd-catalyzed direct C–H bond heteroarylation

Laure Théveau , Cédric Schneider , Olivier Querolle , Lieven Meerpoel , Vincent Levacher , et al.
Organic & Biomolecular Chemistry, 2016, 14 (13), pp.3459-3468. ⟨10.1039/c6ob00227g⟩
Article dans une revue hal-02046242v1

Chemoselective Palladium-Catalyzed Direct C–H Arylation of 5-Carboxyimidazoles: Unparalleled Access to Fused Imidazole-Based Tricycles Containing Six-, Seven- or Eight-Membered Rings

Jérémy Thireau , Cédric Schneider , Christine Baudequin , Sandrine Gaurrand , Patrick Angibaud , et al.
European Journal of Organic Chemistry, 2017, 2017 (17), pp.2491-2494. ⟨10.1002/ejoc.201700297⟩
Article dans une revue hal-02046311v1

Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a “Bio-Oxidizable” Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation

Ludovic Peauger , Rabah Azzouz , Vincent Gembus , Mihaela-Liliana Ţînţaş , Jana Sopkova-de Oliveira Santos , et al.
Journal of Medicinal Chemistry, 2017, 60 (13), pp.5909-5926. ⟨10.1021/acs.jmedchem.7b00702⟩
Article dans une revue hal-02043729v1

Palladium catalyzed one-pot sequential Suzuki cross-coupling-direct C-H functionalization of imidazo[1,2-a]pyrazines

Vincent Gembus , Jean-François Bonfanti , Olivier Querolle , Philippe Jubault , Vincent Levacher , et al.
Organic Letters, 2012, 14 (23), pp.6012-6015. ⟨10.1021/ol3029059⟩
Article dans une revue hal-00996587v1

A Meldrum's Acid Based Multicomponent Synthesis of N‐Fmoc‐isoxazolidin‐5‐ones: Entry to N‐Fmoc‐β‐amino Acids

Alexandra Le Foll , Emmanuel Deau , Emilie Corrot , Laurent Bischoff , Vincent Levacher , et al.
European Journal of Organic Chemistry, 2017, 2017 (22), pp.3265-3273. ⟨10.1002/ejoc.201700472⟩
Article dans une revue hal-02046289v1

Enantioselective Catalytic Formation of 3-Substituted Dihydrocoumarin Derivatives

Thomas Martzel , Vincent Levacher , Sylvain Oudeyer , Jean-François Brière
Séminaire industriel, Janssen, Sep 2019, Mont-Saint-Aignan, France
Communication dans un congrès hal-02376266v1

C5-disubstituted Meldrum's acid derivatives as platform for the organocatalytic synthesis of C3-alkylated dihydrocoumarins

Thomas Martzel , Julien Annibaletto , Vincent Levacher , Jean-François Brière , Sylvain Oudeyer
European symposium on organic chemistry (ESOC, 21, 2019), Jul 2019, Vienne, Austria
Poster de conférence hal-02376282v1

Organocatalyzed one-pot deracemization of alpha-substituted ketones via enantioselective protonation reaction

Claire Segovia , Jérémy Godemert , Sylvain Oudeyer , Vincent Levacher
Journée de l’Ecole doctorale normande de chimie (JEDNC, 2019), Jun 2019, Rouen, France
Poster de conférence hal-02376270v1

Organocatalyzed Multicomponent Synthesis of Isoxazolidin-5-ones

Christophe Berini , Muriel Sebban , Hassan Oulyadi , Morgane Sanselme , Vincent Levacher , et al.
Organic Letters, 2015, 17 (21), pp.5408-5411. ⟨10.1021/acs.orglett.5b02755⟩
Article dans une revue hal-02046141v1

Dihydroquinoline Carbamate Derivatives as "Bio-oxidizable" Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [¹¹C] Radiosynthesis and Biological Evaluation

Pierre Bohn , F. Gourand , Cyril Papamicaël , M. Ibazizène , M Dhilly , et al.
ACS Chemical Neuroscience, 2015, 6 (5), pp.737-744. ⟨10.1021/cn5003539⟩
Article dans une revue hal-01578046v1

Metal or ammonium alginates as Lewis base catalysts for the 1,2-addition of silyl nucleophiles to carbonyl compounds

Cécile Verrier , Sylvain Oudeyer , Isabelle Dez , Vincent Levacher
Tetrahedron Letters, 2012, 53 (15), pp.1958-1960. ⟨10.1016/j.tetlet.2012.02.012⟩
Article dans une revue istex hal-00734701v1

Synthesis and biological evaluation of a novel (99m)Tc labeled 2-nitroimidazole derivative as a potential agent for imaging tumor hypoxia.

Yoann Joyard , Vadim Le Joncour , Hélène Castel , Chérif Bounana Diouf , Laurent Bischoff , et al.
Bioorganic and Medicinal Chemistry Letters, 2013, 23 (13), pp.3704-3708. ⟨10.1016/j.bmcl.2013.05.015⟩
Article dans une revue istex hal-00997430v1

Synthesis of pyrazolines by a site isolated resin-bound reagents methodology

Vincent Gembus , Jean-Jacques Bonnet , François Janin , Pierre Bohn , Vincent Levacher , et al.
Organic & Biomolecular Chemistry, 2010, 8 (14), pp.3287-3293. ⟨10.1039/c004704j⟩
Article dans une revue istex hal-00992140v1

Phase-transfer catalyzed asymmetric decarboxylative protonation reaction involving Meldrum’s acid derivatives and phenols

Fabien Legros , Thomas Martzel , Sylvain Oudeyer , Jean-François Brière , Vincent Levacher
European symposium on organic chemistry (ESOC, 20, 2017), Jul 2017, Cologne, Germany
Poster de conférence hal-02373920v1

Combination between meldrum’s acid derivatives and chiral ammonium phenoxides for an assymetric decarboxylative protonation reaction

Fabien Legros , Jean-François Brière , Sylvain Oudeyer , Vincent Levacher
Journées de chimie organique (JCO, 2016), Sep 2016, Palaiseau, France
Poster de conférence hal-02374227v1
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Recent Advances in Catalytic and Technology-Driven Radical Addition to N,N-Disubstituted Iminium Species

Sylvain Oudeyer , Vincent Levacher , Hélène Beucher , Jean-François Brière
Molecules, 2023, 28 (3), pp.1071. ⟨10.3390/molecules28031071⟩
Article dans une revue hal-03954900v1

Enantioselective Organocatalyzed alpha-Sulfanylation of Isoxazolidin-5-ones : an Approach to beta 2,2-Amino Acids

Timothée Cadard , Vincent Levacher , Perrio Stéphane
Journée de l’Ecole doctorale normande de chimie (JEDNC, 2016), Jun 2016, Caen, France
Communication dans un congrès hal-02299440v1

Access to Highly Enantioenriched Donepezil-like 1,4-Dihydropyridines as Promising Anti-Alzheimer Prodrug Candidates via Enantioselective Tsuji Allylation and Organocatalytic Aza-Ene-Type Domino Reactions

Mihaela-Liliana Tîntas , R. Azzouz , L. Peauger , Vincent Gembus , Emilie Petit , et al.
Journal of Organic Chemistry, 2018, 83 (17), pp.10231-10240. ⟨10.1021/acs.joc.8b01442⟩
Article dans une revue hal-02024535v1

Multicomponent organocatalytic synthesis of 1,5-diazabicyclo[3.3.0]octane-2,6-diones and derivatives: regio- and stereoselective approaches

Arthur Lebrêne , Etienne Pair , Christophe Berini , Romain Noël , Vincent Levacher , et al.
Journées de chimie organique (JCO, 2019), Oct 2019, Palaiseau, France
Poster de conférence hal-02376368v1

Palladium-Catalyzed Carbonylation of (Hetero)Aryl, Alkenyl and Allyl Halides by Means of N-Hydroxysuccinimidyl Formate as CO Surrogate

Anaïs Barré , Mihaela-Liliana Tîntas , Florent Alix , Vincent Gembus , Cyril Papamicaël , et al.
Journal of Organic Chemistry, 2015, 80 (13), pp.6537-6544. ⟨10.1021/acs.joc.5b01119⟩
Article dans une revue hal-02046139v1

Multicomponent organocatalytic synthesis of isoxazolidin-5-ones

Julien Annibaletto , Christophe Berini , Vincent Levacher , Sylvain Oudeyer , Jean-François Brière
European symposium on organic chemistry (ESOC, 21, 2019), Jul 2019, Vienne, Austria
Poster de conférence hal-02376286v1