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Vincent Jonchère, Chargée de Recherche à l’UMR Biologie des Oiseaux et Aviculture (BOA)

 

Docteur en biologie de la reproduction et du développement, l’essentiel de mes travaux de recherche a porté sur l’étude de la biologie des épithéliums dans de nombreux modèles physiologiques. J’ai étudié les mécanismes responsables de la formation de la coquille d’œuf chez la poule, les effets du stress périnatal chez le xénope et plus récemment les conséquences de l’instabilité génomique dans différents tissus digestifs chez l’humain. Ma thématique de recherche au sein de l’UMR BOA vise à identifier les mécanismes de programmation précoce des fonctionnalités digestives afin d’améliorer et de diversifier l’utilisation des ressources alimentations. J’étude les conséquences d’une modulation de l’alimentation durant la période périnatale sur le développement des fonctionnalités digestives des oiseaux d'élevage

Journal articles14 documents

  • Romain Cohen, Vincent Jonchère, Christelle de la Fouchardière, Toky Ratovomanana, Quentin Letourneur, et al.. Adrenal gland as a sanctuary site for immunotherapy in patients with microsatellite instability-high metastatic colorectal cancer. Journal for Immunotherapy of Cancer, BMJ Publishing Group 2021, 9 (2), pp.e001903. ⟨10.1136/jitc-2020-001903⟩. ⟨hal-03141378⟩
  • Magali Svrcek, Olivier Lascols, Romain Cohen, Ada Collura, Vincent Jonchère, et al.. MSI/MMR-deficient tumor diagnosis: Which standard for screening and for diagnosis? Diagnostic modalities for the colon and other sites: Differences between tumors. Bulletin du Cancer, John Libbey Eurotext, 2019, 106 (2), pp.119-128. ⟨10.1016/j.bulcan.2018.12.008⟩. ⟨hal-02179325⟩
  • Vincent Jonchère, Nicolas Buisine, Corinne Blugeon, Laurent Sachs. Thyroid hormone effects on the methylome during post-embryonic development. Journal of the Endocrine Society, Oxford University Press, 2019, ENDO 2019 Abstracts - 101st Annual Meeting of the Endocrine Society – March 23 – 26th, 2019 – New Orleans, Louisiana 3 (Supplement_1), ⟨10.1210/js.2019-SAT-551⟩. ⟨hal-02928599⟩
  • Laetitia Marisa, Magali Svrcek, Ada Collura, Etienne Becht, Pascale Cervera, et al.. The Balance Between Cytotoxic T-cell Lymphocytes and Immune Checkpoint Expression in the Prognosis of Colon Tumors. JNCI: Journal of the National Cancer Institute, Oxford University Press (OUP), 2018, 110 (1), pp.68-77. ⟨10.1093/jnci/djx136⟩. ⟨hal-01727817⟩
  • A'Dem Bokhari, Vincent Jonchère, Anaïs Lagrange, Romane Bertrand, Magali Svrcek, et al.. Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability. Oncogenesis, Nature Publishing Group: Open Access Journals - Option C, 2018. ⟨hal-03071655⟩
  • Vincent Jonchère, Laetitia Marisa, Malorie Greene, Alain Virouleau, Olivier Buhard, et al.. Identification of Positively and Negatively Selected Driver Gene Mutations Associated With Colorectal Cancer With Microsatellite Instability Positive Selection Pressure Mutational Background Negative Selection Pressure Mutational Frequency Microsatellite length (bp). Cellular and Molecular Gastroenterology and Hepatology, Philadelphia, PA : American Gastroenterological Association, [2015]-, 2018, 6 (3), pp.277-300. ⟨10.1016/j.jcmgh.2018.06.002⟩. ⟨hal-02180261⟩
  • Vincent Jonchère, Nada Alqadri, John Herbert, Lauren Dodgson, David Mason, et al.. Transcriptional responses to hyperplastic MRL signalling in Drosophila. Open Biology, Royal Society, 2017, 7 (2), pp.160306. ⟨10.1098/rsob.160306⟩. ⟨hal-03071683⟩
  • Brice Bellessort, Marine Le Cardinal, Anne Bachelot, Nicolas Narboux-Nême, Paolo Garagnani, et al.. Dlx5 and Dlx6 control uterine adenogenesis during post-natal maturation: possible consequences for endometriosis. Human Molecular Genetics, Oxford University Press (OUP), 2015, 25 (1), pp.97-108. ⟨10.1093/hmg/ddv452⟩. ⟨hal-02135783⟩
  • Anita Ciurciu, Louise Duncalf, Vincent Jonchère, Nick Lansdale, Olga O. Vasieva, et al.. PNUTS/PP1 Regulates RNAPII-Mediated Gene Expression and Is Necessary for Developmental Growth. PLoS Genetics, Public Library of Science, 2013, 9 (10), pp.e1003885. ⟨10.1371/journal.pgen.1003885⟩. ⟨hal-03073712⟩
  • Vincent Jonchère, Daimark Bennett. Validating RNAi Phenotypes in Drosophila Using a Synthetic RNAi-Resistant Transgene. PLoS ONE, Public Library of Science, 2013, 8 (8), pp.e70489. ⟨10.1371/journal.pone.0070489⟩. ⟨hal-03071690⟩
  • Vincent Jonchère, Aurélien Brionne, Joël Gautron, Yves Nys. Identification of uterine ion transporters for mineralisation precursors of the avian eggshell. BMC Physiology, BioMed Central, 2012, 12, 17 p. ⟨10.1186/1472-6793-12-10⟩. ⟨hal-02642183⟩
  • Vincent Jonchère, Sophie Réhault-Godbert, Christelle Hennequet-Antier, Cédric Cabau, Vonick Sibut, et al.. Gene expression profiling to identify eggshell proteins involved in physical defense of the chicken egg. BMC Genomics, BioMed Central, 2010, 11 (57), 19 p. ⟨10.1186/1471-2164-11-57⟩. ⟨hal-02662318⟩
  • Joël Gautron, Sophie Réhault-Godbert, Vincent Jonchère, Virginie Herve-Grepinet, K. Mann, et al.. L'apport des techniques à haut débit (protéomique et transcriptomique) dans l'identification et la caractérisation fonctionnelle des protéines de l'oeuf. INRA Productions Animales, Paris: INRA, 2010, 23 (2), pp.133-140. ⟨hal-02666661⟩
  • Yves Nys, M.-T. Hincke, A. Hernandez-Hernandez, A.-B. Rodriguez-Navarro, J. Gomez-Morales, et al.. Structure, propriétés et minéralisation de la coquille de l'œuf : rôle de la matrice organique dans le contrôle de sa fabrication. INRA Productions Animales, Paris: INRA, 2010, 23 (2), pp.143-154. ⟨hal-02667365⟩

Conference papers20 documents

  • Vincent Jonchère, Ada Collura, Alex Duval. Identification of positively and negatively selected driver gene mutations associated with colorectal cancer with microsatellite instability. Annual SMB Meetings – Society for Mathematical Biology, Jun 2021, Online, Germany. ⟨hal-03262153⟩
  • Vincent Jonchère, Alexis Grimaldi, Nicolas Buisine, Laurent Sachs. Thyroid Hormone effects on the methylome during Post-embryonic development. Journée de Séminaires du Département Phase sur l'Epigénétique EpiPhase, Jun 2021, Lyon - Online, France. ⟨hal-03262140⟩
  • Vincent Jonchère, Corinne Blugeon, J. Pouch, Laurent Sachs, Nicolas Buisine. DNA methylation landscape changes during thyroid hormone and glucocorticoid crosstalks at Xenopus metamorphosis.. ISAREN (International Symposium on Amphibian and Reptile Endocrinology): Epigenetic Analysis in Amphibian and Reptile Endocrinology and Neurobiology, 5th Biennial North American Society for Comparative Endocrinology, 2019, Gainesville, United States. ⟨hal-03072421⟩
  • Vincent Jonchère, Ada Collura, Alex Duval. Identification of positively and negatively selected driver gene mutations associated with colorectal cancer with microsatellite instability.. Seminaire Carte d’Identité des Tumeurs, 2018, Paris, France. ⟨hal-03072770⟩
  • Vincent Jonchère, Nicolas Buisine, Corinne Blugeon, Laurent Sachs. Corticosterone affects thyroid hormones induced modifications of the methylome.. 41th Annual Meeting of the European Thyroid Association, 2018, Newcastle, United Kingdom. ⟨hal-03072572⟩
  • Alexis Grimaldi, Nicolas Buisine, Vincent Jonchère, Corinne Blugeon, Laurent Sachs. Stress sensitivity of limb development in Xenopus Tropicalis Tadpoles.. IDEAL Final Meeting 2015, 2015, Leiden, Netherlands. ⟨hal-03072974⟩
  • Vincent Jonchère, Alexis Grimaldi, Nicolas Buisine, Laurent Sachs. Molecular crosstalk between thyroid hormones & glucocorticoides affects skeleton development.. IDEAL annual meeting, 2014, Leiden, Netherlands. ⟨hal-03073190⟩
  • Vincent Jonchère, Daimark Bennett. Identification of transcriptional targets & mechanisms of MRL proteins to promote cell cycle progression /growth. Bioinformatics/computational biology/systems biology seminar, 2013, Liverpool, United Kingdom. ⟨hal-03073291⟩
  • Vincent Jonchère, Lauren Dodgson, Daimark Bennett. Growth control by the actin cytoskeleton: transcriptional targets of MRL/SRF signaling. Fly meeting, 2012, Manchester, France. ⟨hal-03073379⟩
  • Vincent Jonchère, Joël Gautron, Agnès Narcy, Aurélien Brionne, Yves Nys. Gene identification coding uterine proteins supplying the minerals for eggshell formation. 13. European Poultry Conference (EPC 2010), Aug 2010, Tours, France. ⟨hal-02752419⟩
  • Vincent Jonchère, Sophie Réhault-Godbert, Christelle Hennequet, Cédric Cabau, Vonick Sibut, et al.. Identification de nouveaux genes de la coquille potentiellement impliqués dans les défenses naturelles de l'oeuf. 8. Journées de la Recherche Avicole, Mar 2009, Saint-Malo, France. ⟨hal-02751014⟩
  • Vincent Jonchère, Yves Nys, L. Cogburn, Christelle Hennequet-Antier, Cédric Cabau, et al.. Identification par une approche transcriptomique d'un ensemble de protéines potentiellement impliquées dans la formation de la coquille de l'oeuf de poule. 11. Journées Françaises de Biologie des Tissus Minéralisés, Mar 2009, Nice, France. ⟨hal-02756159⟩
  • Vincent Jonchère, Sophie Réhault-Godbert, L. Cogburn, Christelle Hennequet-Antier, Cédric Cabau, et al.. Screening of novel uterine proteins involved in eggshell formation using cDNA microarrays. 19. European Symposium on the Quality of Poultry Meat. 13. European Symposium on the Quality of Eggs and Eggs Products., Jun 2009, Turku, Finland. ⟨hal-02751521⟩
  • Joël Gautron, K. Mann, P.G. Righetti, Sophie Réhault-Godbert, Vincent Jonchère, et al.. Functional genomics reveals numerous novel egg proteins. 19. European Symposium on the Quality of Poultry Meat. 13. European Symposium on the Quality of Eggs and Eggs Products., Jun 2009, Turku, Finland. ⟨hal-02755471⟩
  • Vincent Jonchère, Yves Nys, L.A. Cogburn, Christelle Hennequet, Vonick Sibut, et al.. Identification of new chicken genes coding eggshell proteins potentially involved in the physical defence on the egg using cDNA arrays. 23. World's Poultry Congress, Jun 2008, Brisbane, Australia. ⟨hal-02752448⟩
  • Christelle Hennequet-Antier, Vincent Jonchère, Sophie Réhault-Godbert, L.A. Cogburn, Vonick Sibut, et al.. Comparison of statistical methods (t-test and mixed model) to identify differentially expressed genes between regions of the laying egg oviduct in loop design microarray experiment. Journées ouvertes Biologie Informatique Mathématiques 2008, Jun 2008, Lille, France. ⟨hal-02752405⟩
  • Joël Gautron, Sophie Réhault-Godbert, Vincent Jonchère, Virginie Herve-Grepinet, Yves Nys. Use of high-throughput technologies to identify new egg components with novel biological activities. International Egg Symposium: "The Return of the Good Egg", Nov 2008, Istanbul, Turkey. ⟨hal-02757347⟩
  • Joël Gautron, Sophie Réhault-Godbert, Vincent Jonchère, L.A. Cogburn, Christelle Hennequet, et al.. Transcriptional profiling to identify novel antimicrobial egg proteins. 23. World's Poultry Congress, Jun 2008, Brisbane, Australia. ⟨hal-02757395⟩
  • Joël Gautron, Vincent Jonchère, Christelle Hennequet-Antier, Cédric Cabau, Valérie Labas, et al.. Use of high-throughput methods to identify novel egg components. 25. Congrès de la Société d'Electrophorèse et d'Analyse Protéomique, Oct 2008, Tours, France. ⟨hal-02751763⟩
  • Vincent Jonchère, Larry A. Cogburn, Christelle Hennequet, Wilfrid Carre, Vonick Sibut, et al.. Transcriptional profiling to identify hen egg proteins involved in the egg's natural defences. 18. European Symposium on the Quality of Poultry Meat, Sep 2007, Prague, Czech Republic. ⟨hal-02757086⟩

Poster communications5 documents

  • Vincent Jonchère, Laëtitia Marisa, Malorie Greene, Ada Collura, Alex Duval. Identification of negatively selected driver gene mutations associated with colorectal cancer with microsatellite instability.. Gordon Conference: DNA Damage, mutations and cancer, 2018, Ventura, United States. ⟨hal-03071728⟩
  • Alexis Grimaldi, Nicolas Buisine, Vincent Jonchère, Corinne Blugeon, Laurent Sachs. Glucocorticoids affect gene regulation by thyroid hormones during limb development in Xenopus tropicalis.. ENDO Annual Meeting 2015, 2015, San Diego, France. ⟨hal-03071759⟩
  • Vincent Jonchère, Daimark Bennett. Growth control by the actin cytoskeleton: transcriptional targets of MRL/SRF signaling.. CRUK Annual Meeting, 2012, Liverpool, United Kingdom. ⟨hal-03071951⟩
  • Vincent Jonchère, Valérie Labas, Cécile Lahuec, Nadine Gérard. Studying bio markers of ovulation by proteomic analysis. Congrès de la Société Française d'Electrophorèse et d'Analyse Protéomique, Oct 2006, Saint-Malo, France. n.p., 2006. ⟨hal-02812338⟩
  • Maud Caillaud, Cécile Lahuec, Vincent Jonchère, Nadine Gérard. In vitro effect of interleukin-1b (IL-1b) and interleukin-1 receptor antagonist (IL-1RA) on equine oocyte maturation and on cumulus cells genes expression. ESHRE Campus 2005 : Mammalian Oogenesis and Folliculogenesis, Mar 2005, Paris, France. 2005. ⟨hal-02759309⟩

Patents1 document

  • Alex Duval, Vincent Jonchère, Ada Collura, Laëtitia Marisa, Aurelien de Reynies. METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING CANCER. France, Patent n° : WO/2019/185683. 2019. ⟨hal-03072167⟩

Theses1 document

  • Vincent Jonchère. Identification de gènes et de protéines de l'utérus impliqués dans le transfert minéral, la calcification de la coquille et la protection antimicrobienne de l'oeuf de poule. Sciences du Vivant [q-bio]. Université François Rabelais (Tours), 2010. Français. ⟨tel-02820789⟩