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HUIN Vincent, M.D., Ph.D.


 

HUIN Vincent, M.D., Ph.D.

 

 

 

 

 

Associate professor in Biochemistry and Molecular Biology, University of Lille, France

 

Univ. Lille, Inserm, CHU Lille, Lille Neuroscience & Cognition, UMR-S1172, Team "Alzheimer & Tauopathies"

 

vincent.huin@inserm.fr / vincent.huin@chru-lille.fr

 

Tel: +33 359 899 605 / Fax: +33 320 538 562

 

French citizen

 

 

 

EDUCATION

 

INSTITUTION AND LOCATION DEGREE YEAR FIELD OF STUDY

 

University of Lille, Faculty of Medicine, Bachelor of Medicine                                                           2007

 

University of Lille, B.Sc. (Master 1), Research in Biology-Health                                                         2005

 

University of Rouen, B.Sc. (Master 1), Medical/Pharmaceutical Sciences & Biology-Health         2009

 

University of Lille, M.Sc. (Master 2), Research in Biology-Health                                                         2011

 

University of Rouen and University Hospital of Rouen, M.D. Medical biology & genetics              2012

 

University of Paris Descartes, Paris (DIU), Diploma of Inborn errors of metabolism                         2013

 

National examination for the position of hospital doctor,Medical biology                                       2016

 

University of Lille, Ph.D in Neurosciences                                                                                                2016

 

University of Pierre et Marie Curie, Paris (DIU), Diploma of medical pedagogy                                 2019

 

 

 

EMPLOYMENT

 

University Hospital of Lille, Professional practice and internship                                                      2003-2007

 

University Hospital of Rouen, Postgraduate experience as Medical Intern                                      2007-2012

 

University Hospital of Lille, Specialty Registrar                                                                                     2012-2017

 

Institut du Cerveau et de la moelle épinière (ICM), Paris, PostPh.D.                                                   2017-2018

 

University of Lille and University Hospital of Lille, Associate professor                                           2018-present

 

 

 

OTHER ACADEMIC POSITIONS

 

Speech Therapy School of Lille, Head teacher in Biochemistry and Molecular Biology             2013-2016

 

 

 

HONORS and MEMBERSHIPS

 

Societies: Society for Neuroscience France; Association Nationale des Praticiens de Génétique Moléculaire (ANPGM); Société Française de Biochimie et Biologie Moléculaire; Collège national des Biochimistes et Biologistes Moléculaires Médicaux (CBBMM)

 

• Networks: Member of the clinical and genetics analysis of Spastic paraplegia and Ataxia network (European Spatax network); "BRAIN-TEAM": Filière de Santé Maladies Rares

 

Conference as invited speaker:

 

National scientific symposium of the charity « connaître les syndromes cérébelleux », France      2016

 

Reviewer for the journal “Orphanet Journal of Rare Diseases”, "Scientific Reports" and "Neurology: Genetics"

 


Journal articles14 documents

  • Vincent Huin, Mathieu Barbier, Alexandra Durr, Isabelle Le Ber. Reply: Two heterozygous Progranulin mutations in progressive supranuclear palsy. Brain - A Journal of Neurology , Oxford University Press (OUP), 2021, ⟨10.1093/brain/awaa456⟩. ⟨hal-03113276⟩
  • Vincent Huin, Mathieu Barbier, Alexandra Durr, Isabelle Le Ber. Reply: Early-onset phenotype of bi-allelic GRN mutations. Brain - A Journal of Neurology , Oxford University Press (OUP), 2020, ⟨10.1093/brain/awaa415⟩. ⟨hal-03113239⟩
  • Mégane Homa, Anne Loyens, Sabiha Eddarkaoui, Emilie Faivre, Vincent Deramecourt, et al.. The TMEM240 Protein, Mutated in SCA21, Is Expressed in Purkinje Cells and Synaptic Terminals: TMEM240 localization in the cerebellum. The Cerebellum, Springer, In press, Ahead of print. ⟨10.1007/s12311-020-01112-y⟩. ⟨inserm-02463227v2⟩
  • Vincent Huin, Mathieu Barbier, Armand Bottani, Johannes Lobrinus, Fabienne Clot, et al.. Homozygous GRN mutations: unexpected phenotypes and new insights into pathological and molecular mechanisms: New insights in homozygous GRN mutations. Brain - A Journal of Neurology , Oxford University Press (OUP), 2020, 143 (1), pp.303-319. ⟨10.1093/brain/awz377⟩. ⟨inserm-03014481v2⟩
  • Vincent Huin, Mathieu Barbier, Armand Bottani, Johannes Alexander Lobrinus, Fabienne Clot, et al.. Homozygous GRN mutations: new phenotypes and new insights into pathological and molecular mechanisms. Brain - A Journal of Neurology , Oxford University Press (OUP), 2020, 143 (1), pp.303-319. ⟨10.1093/brain/awz377⟩. ⟨hal-02437674⟩
  • Jean Christophe Corvol, Fábio Carneiro, Dario Saracino, Vincent Huin, Fabienne Clot, et al.. Isolated parkinsonism is an atypical presentation of GRN and C9orf72 gene mutations Authors. Parkinsonism and Related Disorders, Elsevier, 2020, 80, pp.73-81. ⟨10.1016/j.parkreldis.2020.09.019⟩. ⟨hal-03146705⟩
  • Kevin Carvalho, Emilie Faivre, Marie Pietrowski, Xavier Marques, Victoria Gomez-Murcia, et al.. Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor. Brain - A Journal of Neurology , Oxford University Press (OUP), 2019, 142 (11), pp.3636-3654. ⟨10.1093/brain/awz288⟩. ⟨inserm-02350065⟩
  • Kevin Carvalho, Emilie Faivre, Marie Pietrowski, Xavier Marques, Victoria Gomez-Murcia, et al.. Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor. Brain - A Journal of Neurology , Oxford University Press (OUP), 2019, 142 (11), pp.3636-3654. ⟨10.1093/brain/awz288⟩. ⟨hal-03086114⟩
  • Vincent Huin, Claire-Marie Dhaenens, Mégane Homa, Kévin Carvalho, Luc Buée, et al.. Neurogenetics of the Human Adenosine Receptor Genes: Genetic Structures and Involvement in Brain Diseases. Journal of Caffeine and Adenosine Research, New Rochelle, N.Y. : Mary Ann Liebert, Inc., [2018]-, 2019, 9 (3), pp.73-88. ⟨10.1089/caff.2019.0011⟩. ⟨inserm-02460598⟩
  • Vincent Huin, Isabelle Strubi-Vuillaume, Kathy Dujardin, Marine Brion, Marie Delliaux, et al.. Expanding the phenotype of SCA19/22: Parkinsonism, cognitive impairment and epilepsy. Parkinsonism and Related Disorders, Elsevier, 2017, Parkinsonism & related disorders, 45, pp.85-89. ⟨10.1016/j.parkreldis.2017.09.014⟩. ⟨hal-02467104v2⟩
  • Vincent Huin, Vincent Deramecourt, Dominique Caparros-Lefebvre, Claude Maurage, Charles Duyckaerts, et al.. Alternative promoter usage generates novel shorter MAPT mRNA transcripts in Alzheimer’s disease and progressive supranuclear palsy brains. Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.12589. ⟨10.1038/s41598-017-12955-7⟩. ⟨inserm-02460428⟩
  • Vincent Huin, Vincent Deramecourt, Dominique Caparros-Lefebvre, Claude-Alain Maurage, Charles Duyckaerts, et al.. The MAPT gene is differentially methylated in the progressive supranuclear palsy brain: Hypomethylation of MAPT in PSP brain. Movement Disorders, Wiley, 2016, 31 (12), pp.1883-1890. ⟨10.1002/mds.26820⟩. ⟨hal-03015965v2⟩
  • Dominique Caparros-Lefebvre, Lawrence Golbe, Vincent Deramecourt, Claude-Alain Maurage, Vincent Huin, et al.. A geographical cluster of progressive supranuclear palsy in northern France. Neurology, American Academy of Neurology, 2015, 85 (15), pp.1293-1300. ⟨10.1212/WNL.0000000000001997⟩. ⟨inserm-02460488⟩
  • Jérôme Delplanque, David Devos, Vincent Huin, Alexandre Genet, Olivier Sand, et al.. TMEM240 mutations cause spinocerebellar ataxia 21 with mental retardation and severe cognitive impairment. Brain - A Journal of Neurology , Oxford University Press (OUP), 2014, 137 (10), pp.2657-2663. ⟨10.1093/brain/awu202⟩. ⟨inserm-03017555⟩

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