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Conformational space exploration of cryo-EM structures by variability refinement

Pavel V Afonine , Alexia Gobet , Loïck Moissonnier , Juliette Martin , Billy K Poon , et al.
Biochimica et Biophysica Acta:Biomembranes, 2023, 1865 (4), pp.184133. ⟨10.1016/j.bbamem.2023.184133⟩
Article dans une revue hal-04022885v1
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The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains

Margot Di Cesare , Elise Kaplan , Julia Rendon , Guillaume Gerbaud , Sepideh Valimehr , et al.
Journal of Biological Chemistry, 2024, 300 (1), pp.105546. ⟨10.1016/j.jbc.2023.105546⟩
Article dans une revue hal-04435310v1

Crystal structure and functional analysis identify the P-loop containing protein YFH7 of Saccharomyces cerevisiae as an ATP-dependent kinase.

Virginie Gueguen-Chaignon , Vincent Chaptal , Laurent Larivière , Narciso Costa , Philippe Lopes , et al.
Proteins - Structure, Function and Bioinformatics, 2008, 71 (2), pp.804-12. ⟨10.1002/prot.21740⟩
Article dans une revue istex hal-00412425v1
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Overexpression of the ABC Transporter BmrA Within Intracellular Caveolae in Escherichia coli

Alexia Gobet , Christine Jaxel , Sandrine Magnard , Manuel Garrigos , Stéphane Orlowski , et al.
Heterologous Expression of Membrane Proteins, 2507, Springer US, pp.79-89, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2368-8_5⟩
Chapitre d'ouvrage hal-04112236v1
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Drug-bound and -free outward-facing structures of a multidrug ABC exporter point to a swing mechanism

Vincent Chaptal , Veronica Zampieri , Benjamin Wiseman , Cédric Orelle , Juliette Martin , et al.
2021
Pré-publication, Document de travail hal-03388821v1

X-ray structure of a domain-swapped dimer of Ser46-phosphorylated Crh from Bacillus subtilis

Vincent Chaptal , Laurent Larivière , Virginie Gueguen-Chaignon , Anne Galinier , Sylvie Nessler , et al.
Proteins - Structure, Function and Bioinformatics, 2006, 63 (1), pp.249-251. ⟨10.1002/prot.20816⟩
Article dans une revue hal-02345005v1

Structural analysis of B. subtilis CcpA effector binding site.

Vincent Chaptal , Virginie Gueguen-Chaignon , Sandrine Poncet , Cécile Lecampion , Philippe Meyer , et al.
Proteins - Structure, Function and Bioinformatics, 2006, 64 (3), pp.814-6. ⟨10.1002/prot.21001⟩
Article dans une revue istex hal-00164048v1
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CryoEM reconstructions of membrane proteins solved in several amphipathic solvents, nanodisc, amphipol and detergents, yield amphipathic belts of similar sizes corresponding to a common ordered solvent layer

Veronica Zampieri , Alexia Gobet , Xavier Robert , Pierre Falson , Vincent Chaptal
Biochimica et Biophysica Acta:Biomembranes, 2021, 1863 (11), pp.183693. ⟨10.1016/j.bbamem.2021.183693⟩
Article dans une revue hal-03453888v1
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Molecular analysis of the massive GSH transport mechanism mediated by the human Multidrug Resistant Protein 1/ABCC1

Rachad Nasr , Doriane Lorendeau , Ruttiros Khonkarn , Lauriane Dury , Basile Pérès , et al.
Scientific Reports, 2020, 10 (1), pp.7616. ⟨10.1038/s41598-020-64400-x⟩
Article dans une revue inserm-02863457v1

Quantification of Detergents Complexed with Membrane Proteins

Vincent Chaptal , Frédéric Delolme , Arnaud Kilburg , Sandrine Magnard , Cédric Montigny , et al.
Scientific Reports, 2017, 7, ⟨10.1038/srep41751⟩
Article dans une revue hal-01618281v1
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X-ray diffraction reveals the intrinsic difference in the physical properties of membrane and soluble proteins

Xavier Robert , Josiane Kassis-Sahyoun , Nicoletta Ceres , Juliette Martin , Michael R Sawaya , et al.
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-17216-1⟩
Article dans une revue hal-02329431v1

Nucleotide-free Crystal Structure of Nucleotide-binding Domain 1 from Human ABCC1 Supports a ‘General-Base Catalysis’ Mechanism for ATP Hydrolysis

Vincent Chaptal , Pierre Falson , Sandrine Magnard , Virginie Gueguen-Chaignon , Attilio Di Pietro , et al.
Biochemistry & Pharmacology: Open Access, 2014, 03 (06), ⟨10.4172/2167-0501.1000150⟩
Article dans une revue hal-02442553v1
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X-ray diffraction reveals the intrinsic difference in the physical properties of membrane and soluble proteins

Xavier Robert , Josiane Kassis-Sahyoun , Nicoletta Ceres , Juliette Martin , Michael Sawaya , et al.
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-17216-1⟩
Article dans une revue hal-02110047v1

Diffraction anisotropy falloff in the direction of the detergent belt for two centered monoclinic crystals of OmpF

Vincent Chaptal , Arnaud Kilburg , David Flot , Benjamin Wiseman , Nushin Aghajari , et al.
Data in Brief, 2016, 7, pp.726-729. ⟨10.1016/j.dib.2016.03.031⟩
Article dans une revue hal-02442609v1
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Leishmania tarentolae as a Promising Tool for Expressing Polytopic and Multi-Transmembrane Spans Eukaryotic Membrane Proteins: The Case of the ABC Pump ABCG6

Lucia Gonzalez-Lobato , Vincent Chaptal , Jennifer Molle , Pierre Falson
Heterologous Expression of Membrane Proteins, pp.119-131, 2016, ⟨10.1007/978-1-4939-3637-3_8⟩
Chapitre d'ouvrage hal-02329732v1

Multidrug ABC transporter Cdr1 of Candida albicans harbors specific and overlapping binding sites for human steroid hormones transport

Pratima Baghel , Manpreet Kaur Rawal , Mohammad Firoz Khan , Sobhan Sen , Mohammed Haris Siddiqui , et al.
Biochimica et Biophysica Acta:Biomembranes, 2017, 1859 (10), pp.1778-1789. ⟨10.1016/j.bbamem.2017.05.011⟩
Article dans une revue hal-02329476v1

Gradient reconstitution of membrane proteins for solid-state NMR studies

Denis Lacabanne , Alons Lends , Clément Danis , Britta Kunert , Marie-Laure Fogeron , et al.
Journal of Biomolecular NMR, 2017, 69 (2), pp.81-91. ⟨10.1007/s10858-017-0135-4⟩
Article dans une revue hal-02110050v1

Glycosyl-Substituted Dicarboxylates as Detergents for the Extraction, Overstabilization, and Crystallization of Membrane Proteins

Kim-Anh Nguyen , Marine Peuchmaur , Sandrine Magnard , Romain Haudecoeur , Cédric Boyère , et al.
Angewandte Chemie International Edition, 2018, 57 (11), pp.2948-2952. ⟨10.1002/anie.201713395⟩
Article dans une revue hal-02329303v1
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Structural analysis of the bacterial HPr kinase/phosphorylase V267F mutant gives insights into the allosteric regulation mechanism of this bifunctional enzyme.

Vincent Chaptal , Fanny Vincent , Virginie Gueguen-Chaignon , Vicente Monedero , Sandrine Poncet , et al.
Journal of Biological Chemistry, 2007, 282 (48), epub ahead of print. ⟨10.1074/jbc.M705979200⟩
Article dans une revue hal-00174124v1

Atomic modelling and systematic mutagenesis identify residues in multiple drug binding sites that are essential for drug resistance in the major Candida transporter Cdr1

Shweta Nim , Lucia Gonzalez Lobato , Alexis Moreno , Vincent Chaptal , Manpreet Kaur Rawal , et al.
Biochimica et Biophysica Acta:Biomembranes, 2016, 1858 (11), pp.2858-2870. ⟨10.1016/j.bbamem.2016.08.011⟩
Article dans une revue hal-02329688v1

Two different centered monoclinic crystals of the E. coli outer-membrane protein OmpF originate from the same building block

Vincent Chaptal , Arnaud Kilburg , David Flot , Benjamin Wiseman , Nushin Aghajari , et al.
Biochimica et Biophysica Acta:Biomembranes, 2016, 1858 (2), pp.326-332. ⟨10.1016/j.bbamem.2015.11.021⟩
Article dans une revue hal-02442575v1
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Quantification of Detergents Complexed with Membrane Proteins

Vincent Chaptal , Frédéric Delolme , Arnaud Kilburg , Sandrine Magnard , Cédric Montigny , et al.
Scientific Reports, 2017, 7 (1), ⟨10.1038/srep41751⟩
Article dans une revue hal-02110228v1

HPr kinase/phosphorylase, a Walker motif A-containing bifunctional sensor enzyme controlling catabolite repression in Gram-positive bacteria

Sandrine Poncet , Ivan Mijakovic , Sylvie Nessler , Virginie Gueguen-Chaignon , Vincent Chaptal , et al.
Biochimica et Biophysica Acta Proteins and Proteomics, 2004, 1697 (1-2), pp.123-135. ⟨10.1016/j.bbapap.2003.11.018⟩
Article dans une revue istex hal-02345159v1
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Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter

Vincent Chaptal , Veronica Zampieri , Benjamin Wiseman , Cédric Orelle , Juliette Martin , et al.
Science Advances , 2022, 8 (4), pp.eabg9215. ⟨10.1126/sciadv.abg9215⟩
Article dans une revue hal-03552930v2
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The non-Newtonian behavior of detergents during concentration is increased by macromolecules, in trans, and results in their over-concentration

Alexia Gobet , Veronica Zampieri , Sandrine Magnard , Eva Pebay-Peyroula , Pierre Falson , et al.
Biochimie, 2023, 205, pp.53-60. ⟨10.1016/j.biochi.2022.09.004⟩
Article dans une revue hal-03776505v1
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The Det.Belt Server: A Tool to Visualize and Estimate Amphipathic Solvent Belts around Membrane Proteins

Veronica Zampieri , Cécile Hilpert , Mélanie Garnier , Yannick Gestin , Sébastien Delolme , et al.
Membranes, 2021, 11 (7), pp.459. ⟨10.3390/membranes11070459⟩
Article dans une revue hal-03454174v1

Stubborn Contaminants: Influence of Detergents on the Purity of the Multidrug ABC Transporter BmrA

Benjamin Wiseman , Arnaud Kilburg , Vincent Chaptal , Gina Catalina Reyes-Mejia , Jonathan Sarwan , et al.
PLoS ONE, 2014, 9 (12), pp.e114864. ⟨10.1371/journal.pone.0114864⟩
Article dans une revue hal-02442543v1
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Au courant computation of the PDB to audit diffraction anisotropy of soluble and membrane proteins

Xavier Robert , Josiane Kassis-Sahyoun , Nicoletta Ceres , Juliette Martin , Michael R Sawaya , et al.
Data in Brief, 2018, 19, pp.753-757. ⟨10.1016/j.dib.2018.05.072⟩
Article dans une revue hal-02326014v1