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Researcher identifiers

  • IdHAL : vincent-aucagne

Keywords

Co-authors

Number of documents

140

Vincent AUCAGNE


EDUCATION

  • 1999-2002 - PhD in organic chemistry with higher honors, Université d'Orléans defended in 2003, grant from the French Ministry of Research and Technology
  • 1998-1999 -Master in chemistry and physicochemistry of bioactive compounds with higher honors, Universités Paris V, Paris XI and Orléans

PROFESSIONAL EXPERIENCES

  • 2006 - CNRS Research manager, Centre de Biophysique Moléculaire, Orléans - Team of Dr A. Delmas, Development of new tools for the solid-phase total synthesis of native or modified proteins and glycoproteins

  • 2004-2006 - Postdoctoral Research Associate, School of Chemistry, University of Edinburgh UK - Team of Prof. D. A. Leigh, Towards the total synthesis of the lasso peptide Microcin J25; Active template methodologies for the synthesis of mechanically-interlocked architectures

  • 2002-2003 - Fixed-term Lecturer in organic chemistry (ATER, one year fellowship) Université d'Orléans - Institut de Chimie Organique et Analytique (I.C.O.A.), Team of Prof. L. A. Agrofoglio, synthesis of new nucleoside analogues with antiviral activities

  • 1999-2002 - PhD in organic chemistry , I.C.O.A., team of  Prof. P. Rollin Sulfur-containing phosphonium salts and anomeric Wittig reaction. Evaluation of  vinylthio-functionalized alditols – new tools for stereocontrolled ring closure  reactions

  • 1998-1998 - Postgraduate research fellow , I.C.O.A.; team of Prof. P. Rollin Synthesis of C-glycosidic analogues of glucosinolates

RESEARCH INTERESTS

  • Synthetic chemistry of biomacromolecules : Total synthesis of small proteins and glycoproteins. Click chemistry. Native chemical ligation Amino-acids, carbohydrates and nucleoside analogues. Modified or bioconjugated proteins. Synthetic vaccines. Drug-delivery.

  • Solid-phase organic synthesis : Solid-phase peptide and bio-macromolecule ligation. Solid-phase purification

  • Supramolecular Chemistry : Rotaxanes, Catenanes, Mechanically-interlocked architectures. Coordination chemistry

  • Thiochemistry : Thioester and thioacid peptides. Sulfonylated strained aminoacids. Sulfur as a tool in organic and bioorganic chemistry.

  • Referee for Letters in Organic Chemistry, the Journal of Organic Chemistry, the Journal of the American Chemical Society. Member of the French and American Chemical Societies


Journal articles54 documents

  • Nicolas Guyot, Hervé Meudal, Sascha Trapp, Sophie Iochmann, Anne Silvestre, et al.. Structure, function, and evolution of Gga -AvBD11, the archetype of the structural avian-double-β-defensin family. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2020, 117 (1), pp.337-345. ⟨10.1073/pnas.1912941117⟩. ⟨hal-02522250⟩
  • Charlotte Rieux, Stéphane Goffinont, Franck Coste, Zahira Tber, Julien Cros, et al.. Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. International Journal of Molecular Sciences, MDPI, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩. ⟨hal-02904772⟩
  • Skander Abboud, Vincent Aucagne. An optimized protocol for the synthesis of N -2-hydroxybenzyl-cysteine peptide crypto-thioesters. Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2020, 18 (40), pp.8199-8208. ⟨10.1039/d0ob01737j⟩. ⟨hal-02975540⟩
  • Karine Loth, Agnès Vergnes, Cairé Barreto, Sébastien Voisin, Herve Meudal, et al.. The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets. mBio, 2019, 10 (5), ⟨10.1128/mBio.01821-19⟩. ⟨hal-02994659⟩
  • Karine Loth, Agnès Vergnes, Cairé Barreto, Sébastien Voisin, Hervé Meudal, et al.. The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets. mBio, American Society for Microbiology, 2019, 10 (5), pii: e01821-19. ⟨10.1128/mBio.01821-19⟩. ⟨hal-02328576⟩
  • Monika Cieslikiewicz-Bouet, Svetlana Eliseeva, Vincent Aucagne, A.F. Delmas, Isabelle Gillaizeau, et al.. Near-infrared emitting lanthanide( iii ) complexes as prototypes of optical imaging agents with peptide targeting ability: a methodological approach. RSC Advances, Royal Society of Chemistry, 2019, 9 (3), pp.1747-1751. ⟨10.1039/c8ra09419e⟩. ⟨hal-02064990⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, Marion Georgelin, et al.. The kisspeptin analog C6 is a possible alternative to PMSG (pregnant mare serum gonadotropin) for triggering synchronized and fertile ovulations in the Alpine goat. PLoS ONE, Public Library of Science, 2019, 14 (3), pp.e0214424. ⟨10.1371/journal.pone.0214424⟩. ⟨hal-02088631⟩
  • P.A. Parker, E.A. Coffman, K.G. Pohler, J.A. Daniel, V. Aucagne, et al.. Acute and subacute effects of a synthetic kisspeptin analog, C6, on serum concentrations of luteinizing hormone, follicle stimulating hormone, and testosterone in prepubertal bull calves. Theriogenology, Elsevier, 2019, 130, pp.111-119. ⟨10.1016/j.theriogenology.2019.03.002⟩. ⟨hal-02088608⟩
  • Julien Diharce, Mickaël Cueto, Massimiliano Beltramo, Vincent Aucagne, Pascal Bonnet. In Silico Peptide Ligation: Iterative Residue Docking and Linking as a New Approach to Predict Protein-Peptide Interactions. Molecules, MDPI, 2019, 24 (7), pp.1351. ⟨10.3390/molecules24071351⟩. ⟨hal-02095312⟩
  • Mylène Wartenberg, Ahlame Saidi, Mathieu Galibert, Alix Joulin-Giet, Julien Burlaud-Gaillard, et al.. Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe. Biochimie, Elsevier, 2019, ⟨10.1016/j.biochi.2019.03.013⟩. ⟨hal-02088627⟩
  • David Montoir, Mehdi Amora, Zine El Abidine Aabasa, Vishwanatha Thimmalapura Marulappa, Expédite Yen-Pon, et al.. Synthesis of aryl-thioglycopeptides through chemoselective Pd-Mediated conjugation. Chemical Science , The Royal Society of Chemistry, 2018, 9 (46), pp.8753-8759. ⟨10.1039/C8SC02370K⟩. ⟨hal-02622102⟩
  • Matthieu Galibert, Mylène Wartenberg, Fabien Lecaille, Ahlame Saidi, Sylvie Mavel, et al.. Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S. European Journal of Medicinal Chemistry, Elsevier, 2018, 144, pp.201 - 210. ⟨10.1016/j.ejmech.2017.12.012⟩. ⟨hal-01702303⟩
  • Victor Terrier, Agnès F. Delmas, Vincent Aucagne. Efficient synthesis of cysteine-rich cyclic peptides through intramolecular native chemical ligation of N-Hnb-Cys peptide crypto-thioesters. Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2017, 15 (2), pp.316 - 319. ⟨10.1039/c6ob02546c⟩. ⟨hal-01618781⟩
  • Guillaume Martinez, Jean-Pascal Hograindleur, Sébastien Voisin, Roland Abi Nahed, Tarek M. Abd El Aziz, et al.. Spermaurin, an La1-like peptide from the venom of the scorpion Scorpio maurus palmatus , improves sperm motility and fertilization in different mammalian species. Molecular Human Reproduction, Oxford University Press (OUP), 2017. ⟨hal-01618630⟩
  • Caroline Decourt, Vincent Robert, Karine Anger, Mathieu Galibert, Jean-Baptiste Madinier, et al.. A synthetic kisspeptin analog that triggers ovulation and advances puberty. Scientific Reports, Nature Publishing Group, 2016, 6, pp.26908. ⟨10.1038/srep26908⟩. ⟨hal-01406943⟩
  • Audrey Gambade, Sami Zreika, Maxime Guéguinou, Igor Chourpa, Gaëlle Fromont, et al.. Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells.. Oncotarget, Impact journals, 2016, 7 (17), pp.23785-23800. ⟨10.18632/oncotarget.8122⟩. ⟨hal-01387061⟩
  • Dominique Lelièvre, Victor P. Terrier, Agnès F. Delmas, Vincent Aucagne. Native Chemical Ligation Strategy to Overcome Side Reactions during Fmoc-Based Synthesis of C-Terminal Cysteine-Containing Peptides. Organic Letters, American Chemical Society, 2016, 18 (5), pp.920 - 923. ⟨10.1021/acs.orglett.5b03612⟩. ⟨hal-01407492⟩
  • Karine Loth, Soha Abou Ibrahim Alami, Chahrazed Habès, Solène Garrido, Vincent Aucagne, et al.. Complete 1H, 15N and 13C assignment of trappin-2 and 1H assignment of its two domains, elafin and cementoin. Biomolecular NMR Assignments, Springer, 2016, 10 (1), pp.223 - 226. ⟨10.1007/s12104-016-9671-1⟩. ⟨hal-01407495⟩
  • Victor P. Terrier, Hélène Adihou, Mathieu Arnould, Agnès F. Delmas, Vincent Aucagne. A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters. Chemical Science , The Royal Society of Chemistry, 2016, 7 (1), pp.339 - 345. ⟨10.1039/C5SC02630J⟩. ⟨hal-01407765⟩
  • Michael T. Jacobsen, Mark E. Petersen, Xiang Ye, Mathieu Galibert, George H. Lorimer, et al.. A Helping Hand to Overcome Solubility Challenges in Chemical Protein Synthesis. Journal of the American Chemical Society, American Chemical Society, 2016, 138 (36), pp.11775 - 11782. ⟨10.1021/jacs.6b05719⟩. ⟨hal-01407028⟩
  • Romain Barat, Thibaut Legigan, Isabelle Tranoy-Opalinski, Brigitte Renoux, Elodie Péraudeau, et al.. A mechanically interlocked molecular system programmed for the delivery of an anticancer drug. Chemical Science , The Royal Society of Chemistry, 2015, 6 (4), pp.2608-2613. ⟨10.1039/C5SC00648A⟩. ⟨hal-01170448⟩
  • Mathieu Galibert, Véronique Piller, Friedrich Piller, Vincent Aucagne, Agnès F. Delmas. Combining triazole ligation and enzymatic glycosylation on solid phase simplifies the synthesis of very long glycoprotein analogues. Chemical Science , The Royal Society of Chemistry, 2015, 6 (6), pp.3617-3623. ⟨10.1039/C5SC00773A⟩. ⟨hal-01178852⟩
  • Massimiliano Beltramo, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, Philippe Marceau, et al.. Rational Design of Triazololipopeptides Analogs of Kisspeptin Inducing a Long-Lasting Increase of Gonadotropins. Journal of Medicinal Chemistry, American Chemical Society, 2015, 58 (8), pp.3459-3470. ⟨10.1021/jm5019675⟩. ⟨hal-01170460⟩
  • Isidore E. Decostaire, Dominique Lelièvre, Vincent Aucagne, Agnès F. Delmas. Solid phase oxime ligations for the iterative synthesis of polypeptide conjugates. Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2014, 12 (29), pp.5536-5543. ⟨10.1039/c4ob00760c⟩. ⟨hal-01178857⟩
  • Fanny Meindre, Dominique Lelièvre, Karine Loth, Oriane Mith, Vincent Aucagne, et al.. The nuclear magnetic resonance solution structure of the synthetic AhPDF1.1b plant defensin evidences the structural feature within the γ-motif. Biochemistry, American Chemical Society, 2014, 53 (49), pp.7745-54. ⟨10.1021/bi501285k⟩. ⟨hal-01118914⟩
  • Laurent Raibaut, Hélène Adihou, Rémi Desmet, Agnès F. Delmas, Vincent Aucagne, et al.. Highly efficient solid phase synthesis of large polypeptides by iterative ligations of bis(2-sulfanylethyl)amido (SEA) peptide segments. Chemical Science , The Royal Society of Chemistry, 2013, 4, pp.4061-4066. ⟨10.1039/c3sc51824h⟩. ⟨hal-00944814v2⟩
  • Christelle Gaulier, Audrey Hospital, Bertrand Legeret, Delmas A.F., Vincent Aucagne, et al.. A water soluble Cu-I-NHC for CuAAC ligation of unprotected peptides under open air conditions.. Chemical Communications, Royal Society of Chemistry, 2012, 48, pp.4005-4007. ⟨hal-00711780⟩
  • Antony Fernandes, Aurélien Viterisi, Vincent Aucagne, David A Leigh, Sébastien Papot. Second generation specific-enzyme-activated rotaxane propeptides.. Chemical Communications, Royal Society of Chemistry, 2012, 48 (15), pp.2083-5. ⟨10.1039/c2cc17458h⟩. ⟨hal-00678757⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Kevin J Mark, Martine Cadène, et al.. Initial insights into structure-activity relationships of avian defensins.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (10), pp.7746-55. ⟨10.1074/jbc.M111.312108⟩. ⟨hal-00721842⟩
  • Ibai E Valverde, Fabien Lecaille, Gilles Lalmanach, Vincent Aucagne, Agnès F Delmas. Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.. Angewandte Chemie International Edition, Wiley-VCH Verlag, 2012, 51 (3), pp.718-22. ⟨10.1002/anie.201107222⟩. ⟨hal-00726293⟩
  • Vincent Aucagne, Ibai E Valverde, Philippe Marceau, Mathieu Galibert, Nabil Dendane, et al.. Towards the simplification of protein synthesis: iterative solid-supported ligations with concomitant purifications.. Angewandte Chemie International Edition, Wiley-VCH Verlag, 2012, 51 (45), pp.11320-4. ⟨10.1002/anie.201206428⟩. ⟨hal-00748170⟩
  • Andrea Altieri, Vincent Aucagne, Romen Carrillo, Guy Clarkson, Daniel d'Souza, et al.. Sulfur-containing amide-based [2]rotaxanes and molecular shuttles. Chemical Science , The Royal Society of Chemistry, 2011, 2 (10), pp.1922. ⟨10.1039/C1SC00335F⟩. ⟨hal-02088663⟩
  • Anthony Fernandes, Aurélien Viterisi, Frédéric Coutrot, Stéphanie Potok, David A. Leigh, et al.. Rotaxane-based propeptides: protection and enzymatic release of a bioactive pentapeptide.. Angewandte Chemie International Edition, Wiley-VCH Verlag, 2009, 48 (35), pp.6443-7. ⟨10.1002/anie.200903215⟩. ⟨hal-00467015⟩
  • Chrystelle Derache, Valérie Labas, Vincent Aucagne, Hervé Meudal, Céline Landon, et al.. Primary Structure and Antibacterial Activity of Chicken Bone Marrow-Derived beta-Defensins. Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2009, 53 (11), pp.4647-4655. ⟨10.1128/AAC.00301-09⟩. ⟨hal-00522326⟩
  • Ibai E. Valverde, Agnès F. Delmas, Vincent Aucagne. Click a la carte: robust semi-orthogonal alkyne protecting groups for multiple successive azide/alkyne cycloadditions. Tetrahedron, Elsevier, 2009, 65 (36), pp.7597-7602. ⟨10.1016/j.tet.2009.06.093⟩. ⟨hal-00525398⟩
  • Dominique Lelièvre, P. Barta, Vincent Aucagne, A.F. Delmas. Preparation of peptide thioesters using Fmoc strategy through hydroxyl side chain anchoring. Tetrahedron Letters, Elsevier, 2008, 49 (25), pp.4016-4019. ⟨10.1016/j.tetlet.2008.04.087⟩. ⟨hal-00518141⟩
  • Vincent Aucagne, A. Tatibouët, Patrick Rollin. Thermodynamics versus kinetics in hetero-Michael cyclizations: a highly stereoselective approach to access both epimers of a C-D-mannopyranoside. Tetrahedron Letters, Elsevier, 2008, 49, pp.4750-4753. ⟨10.1016/j.tetlet.2008.05.117⟩. ⟨hal-00512453⟩
  • J. Broggi, N. Joubert, Vincent Aucagne, T. Zevaco, S. Berteina-Raboin, et al.. Study of different copper(I) catalysts for the "click chemistry" approach to carbanucleosides. Nucleosides, Nucleotides and Nucleic Acids, Taylor & Francis, 2007, 26, pp.779-783. ⟨hal-00275217⟩
  • Julie Broggi, Nicolas Joubert, Vincent Aucagne, Sabine Berteina-Raboin, S. Diez-Gonzalez, et al.. Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis. Nucleosides, Nucleotides and Nucleic Acids, Taylor & Francis, 2007, 26 (10-12), pp.1391-1394. ⟨10.1080/15257770701534139⟩. ⟨hal-02086003⟩
  • Vincent Aucagne, J. Berna, Jd Crowley, Sm Goldup, Kd Haenni, et al.. Catalytic "Active-Metal" template synthesis of [2]rotaxanes, [3]rotaxanes, and molecular shuttles, and some observations on the mechanism of the Cu(I)-catalyzed azide-alkyne 1,3-cycloaddition. Journal of the American Chemical Society, American Chemical Society, 2007, 129, pp.11950-11963. ⟨hal-00275210⟩
  • Isidore P. Decostaire, Dominique Lelièvre, Vincent Aucagne, Agnès F. Delmas. Synergic effect of hydride and proton donors in the Pd(0)-mediated deprotection of Nα-Aloc proline derivatives. Tetrahedron Letters, Elsevier, 2007, 48, pp.6523-6526. ⟨10.1016/j.tetlet.2007.07.061⟩. ⟨hal-00166600⟩
  • Vincent Aucagne, David A. Leigh. Chemoselective formation of successive triazole linkages in one pot: "click-click" chemistry. Organic Letters, American Chemical Society, 2006, 8 (20), pp.4505-4507. ⟨10.1021/ol061657d⟩. ⟨hal-00387909⟩
  • Vincent Aucagne, Kevin Hänni, David Leigh, Paul Lusby, D Barney Walker. Catalytic “Click” Rotaxanes: A Substoichiometric Metal-Template Pathway to Mechanically Interlocked Architectures. Journal of the American Chemical Society, American Chemical Society, 2006, 128 (7), pp.2186-2187. ⟨10.1021/ja056903f⟩. ⟨hal-02086010⟩
  • Vincent Aucagne, David Leigh, Julia Lock, Andrew Thomson. Rotaxanes of Cyclic Peptides. Journal of the American Chemical Society, American Chemical Society, 2006, 128 (6), pp.1784-1785. ⟨10.1021/ja057206q⟩. ⟨hal-02086005⟩
  • Vincent Aucagne, Franck Amblard, Luigi Agrofoglio. Highly Efficient AgNO3-Catalyzed Preparation of Substituted Furanopyrimidine Nucleosides [cf. (III)].. ChemInform, Wiley-VCH Verlag, 2005, 36 (18), ⟨10.1002/chin.200518181⟩. ⟨hal-02086027⟩
  • Vanessa Escuret, Vincent Aucagne, Nicolas Joubert, David Durantel, Kimberly Rapp, et al.. Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: Antiviral activity and cellular toxicity. Bioorganic and Medicinal Chemistry, Elsevier, 2005, 13 (21), pp.6015-6024. ⟨10.1016/j.bmc.2005.06.021⟩. ⟨hal-02086013⟩
  • Franck Amblard, Vincent Aucagne, Pierre Guenot, Raymond Schinazi, Luigi Agrofoglio. Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series. Bioorganic and Medicinal Chemistry, Elsevier, 2005, 13 (4), pp.1239-1248. ⟨10.1016/j.bmc.2004.11.057⟩. ⟨hal-02086014⟩
  • V. Aucagne, C. Lorin, A. Tatibouët, P. Rollin. Regioselective Michael-induced cyclisation of γ- and δ-hydroxy vinyl sulfides and vinyl dithiocarbamates. Tetrahedron Letters, Elsevier, 2005, 46 (25), pp.4349-4352. ⟨10.1016/j.tetlet.2005.04.112⟩. ⟨hal-02086017⟩
  • Vincent Aucagne, Sabine Berteina-Raboin, Pierre Guenot, Luigi Agrofoglio. Palladium-Catalyzed Synthesis of Uridines on Polystyrene-Based Solid Supports. Journal of Combinatorial Chemistry, American Chemical Society, 2004, 6 (5), pp.717-723. ⟨10.1021/cc049976o⟩. ⟨hal-02086022⟩
  • Vincent Aucagne, Arnaud Tatibouët, Patrick Rollin. Wittig approach to carbohydrate-derived vinyl sulfides, new substrates for regiocontrolled ring-closure reactions. Tetrahedron, Elsevier, 2004, 60 (8), pp.1817-1826. ⟨10.1016/j.tet.2003.12.040⟩. ⟨hal-02086021⟩
  • Isabelle Gillaizeau, Irene m. Lagoja, Steve p. Nolan, Vincent Aucagne, Jef Rozenski, et al.. Straightforward Synthesis of Labeled and Unlabeled Pyrimidine d4Ns via 2′,3′-Diyne seco Analogues through Olefin Metathesis Reactions. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2003, 2003 (4), pp.666-671. ⟨10.1002/ejoc.200390107⟩. ⟨hal-02086029⟩
  • Vincent Aucagne, Maria Aversa, Anna Barattucci, Paola Bonaccorsi, Placido Giannetto, et al.. Sulfenic acids in the carbohydrate field. Synthesis of transient glycosulfenic acids and their addition to unsaturated acceptors.. Journal of Organic Chemistry, American Chemical Society, 2002, 67 (20), pp.6925-30. ⟨hal-02086034⟩
  • Vincent Aucagne, David Gueyrard, Arnaud Tatibouët, Alain Quinsac, Patrick Rollin. Synthetic Approaches to C-Glucosinolates. Tetrahedron, Elsevier, 2000, 56 (17), pp.2647-2654. ⟨10.1016/S0040-4020(00)00153-8⟩. ⟨hal-02086037⟩
  • V. Aucagne, D. Gueyrard, A. Tatibout, S. Cottaz, H. Driguez, et al.. the first synthesis of c-glucotropeolin. Tetrahedron Letters, Elsevier, 1999, pp.7319-7321. ⟨hal-00309763⟩

Conference papers27 documents

  • D. Montoir, M. Amoura, A. Ababsa Z. E., M. Vishwanatha T., E. Yen-Pon, et al.. Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation. 4th GFPP Chemical Ligation Meeting (Ligation2020), Jan 2020, Orléans, France. ⟨hal-02892772⟩
  • S. Abboud, V. Piller, S. Papot, V. Aucagne. Développement de bras enzymo-labiles pour la synthèse totale de protéines par ligations chimiques sur support solide. 32e Colloque Biotechnocentre, Oct 2019, Seillac, France. ⟨hal-02893386⟩
  • H. Meudal, N. Guyot, K. Loth, G. Jousset, S. Trapp, et al.. Gga-AvBD11, the archetype of a new structural family of defensins. 21eme réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02892790⟩
  • S. Abboud, M. Amoura, V. P. Terrier, A. F. Delmas, V. Aucagne. An improved synthesis of N-Hnb-Cys peptide crypto-thioesters ‒studies on the epimerization of cysteine during solid-phase reductive amination. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02892784⟩
  • G. Lalmanach, M. Wartenberg, M. Galibert, A. Saidi, F. Lecaille, et al.. Design of both pseudopeptide inhibitors and imaging probes derived from a unique substrate sequence: a versatile molecular toolbox for studying proteases. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02892793⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins. Institut de Chimie des Substances Naturelles, Mar 2019, Gif-sur-Yvette, France. ⟨hal-02974369⟩
  • Nicolas Guyot, Hervé Meudal, Karine Loth, Guillaume Jousset, Anne Silvestre, et al.. 1ère structure 3D d’une défensine à double motif β-défensine, Gga-AvBD11 du poulet Gallus gallus, et explorations fonctionnelles. 5. Journées GDR MuFoPAM, Centre National de la Recherche Scientifique (CNRS). FRA., Oct 2018, Paris, France. ⟨hal-02788993⟩
  • Julien Diharce, Mickaël Cueto, Vincent Aucagne, Massimiliano Beltramo, Pascal Bonnet. Fragment covalent docking (FCD) approach: An innovative in silico tools for the prediction of peptide-protein interaction. 256th National Meeting and Exposition of the American-Chemical-Society Nanoscience, Nanotechnology and Beyond (ACS), American Chemical Society (ACS). USA., Aug 2018, Boston, United States. pp.2. ⟨hal-02734800⟩
  • T.M. Vishwanatha, C. Decourt, V.P. Terrier, V. Robert, M. Galibert, et al.. Rational design of kisspeptin analogs for the control of reproduction. 4th Belgian Peptide Group Meeting, Feb 2018, Bruxelles, Belgium. ⟨hal-02892809⟩
  • A.F. Delmas, Vincent Aucagne. Synthesis and structural characterization of naturally-occuring disulfide rich antimicrobial peptides Gyros Protein Technologies. European peptide symposium, Aug 2018, Dublin, Ireland. ⟨hal-02919154⟩
  • M. Amoura, D. Sarraf, L. Nauton, V.P. Terrier, D. Lelièvre, et al.. N-2-hydroxybenzyl-cysteine peptide crypto-thioesters for native chemical ligation. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02892802⟩
  • Vincent Aucagne. Séminaire invité : Développement d’une boîte à outils pour simplifier la synthèse chimique de protéines. Institut des Biomolécules Max Mousseron, Nov 2018, Montpellier, France. ⟨hal-02974372⟩
  • David Montoir, Mehdi Amoura, Zine El Abidine Ababsa, Thimmalapura Marulappa Vishwanatha, Expédite Yen-Pon, et al.. Synthesis of aryl-Thioglycopeptides through chemoselective Pd-catalyzed conjugation. 35 th European Peptide Symposium, Aug 2018, Dublin, Ireland. ⟨hal-02734043⟩
  • Vincent Aucagne. Simplifier la synthèse totale de protéines et de mini-protéines riches en pont disulfures. 7e Symposium Francophone de Synthèse Totale (SFST7), Jun 2017, Orsay, France. ⟨hal-02892762⟩
  • A. Casas-Mora, M. Galibert, A.F. Delmas, V. Aucagne. A non-chromatographic catch-and-release purification method to simplify the synthesis of cysteine-rich peptides. 20e réunion du Groupe Français des Peptides et des Protéines (GFPP 20), Mar 2017, Arcachon, France. ⟨hal-02893392⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins and constrained peptides natural products. Vrije Universiteit Brussel, May 2017, Bruxelles, Belgium. ⟨hal-02974374⟩
  • Vincent Aucagne. Séminaire invité : Développement d'une boîte à outils pour simplifier la synthèse chimique de protéines. Laboratoire BioCIS - Biomolécules : Conception, Isolement et Synthèse, Université Paris-Sud, Apr 2017, Châtenay-Malabry, France. ⟨hal-02974390⟩
  • Vincent Aucagne. Séminaire invité : Triazolopeptides as proteolysis-resistant, highly potent KISS1R agonists. Universiteit Gent, May 2017, Gand, Belgium. ⟨hal-02974376⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins and constrained peptides natural products. Institut Européen de Chimie et Biologie, Apr 2017, Bordeaux, France. ⟨hal-02974400⟩
  • A.F. Delmas, V.P. Terrier, R.D. Rosa, A. Bressan, P. Marceau, et al.. Native Chemical ligation simplifies the access of multidomain antimicrobial peptides: application to the study of big-defensins. International symposium on AntiMicrobial Peptides (AMP2016), Jun 2016, Montpellier, France. ⟨hal-02892834⟩
  • Vincent Aucagne. Séminaire invité : A molecular toolbox for exploring new chemical spaces: making simpler the synthesis of biologically- and therapeutically-relevant small proteins and complex peptides. Sanofi, Sep 2016, Francfort, Germany. ⟨hal-02974403⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins.. Institut Curie, Jun 2016, Paris, France. ⟨hal-02974405⟩
  • Massimiliano Beltramo, Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, et al.. Design and profiling of new selective KISS1R agonists that stimulate the reproductive system. 8. International Congress of Neuroendocrinology, Society for Behavioral Neuroendocrinology (SBN). USA., Aug 2014, Sydney, Australia. ⟨hal-02738894⟩
  • Massimiliano Beltramo, Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, et al.. New KISS1R agonists with potential for the treatment of reproductive disorder. 11. International Symposium on GnRH: The hypothalamic-pituitary-gonadal axis in cancer and reproduction, Kenes International. USA., Feb 2014, Salzburg, Austria. ⟨hal-02742248⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Martine Cadène, Agnès Delmas, et al.. First insights into the structure-activity relationships of avian beta-defensins.. 2nd International Symposium on Antimicrobial Peptides - Food Veterinary Medical and Novel Applications., 2009, Saint-Malo, France. ⟨hal-02753345⟩
  • Anne-Christine Lalmanach, Chrystelle Derache, Evelyne Esnault, Valérie Labas, V. Aucagne, et al.. Avian beta-defensins in the control of bacterial pathogens of chicken digestive tract. 2. International Symposium on Antimicrobial Peptides. Food Veterinary Medical and Novel Applications, Jun 2009, Saint-Malo, France. ⟨hal-02751627⟩
  • P. da Silva, I. Rahioui, C. Laugier, Y. Rahbé, A. Delmas, et al.. PA1b, un peptide à activité insecticide : relations structure/fonction. XVème Colloque de Physiologie de l'Insecte, 2007, Rennes (France), juillet 2007, France. pp.1-1. ⟨hal-00391295⟩

Poster communications53 documents

  • S. Abboud, A.F. Delmas, V. Aucagne. Synthesis of N-Hnb-Cys peptide crypto-thioesters: identification of imadozolidinone and epimerized side products, and development of an optimized protocol. 4th GFPP Chemical Ligation Meeting (Ligation2020), Jan 2020, Orléans, France. ⟨hal-02893398⟩
  • T.M. Vishwanatha, D. Montoir, M. Amoura, Z. El Ababsa, E. Yen-Pon, et al.. Synthesis of Aryl-Thioglycopeptides Through Chemoselective Pd-Catalyzed Conjugation. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02893488⟩
  • T.M. Vishwanatha, D. Montoir, M. Amoura, Z. El Ababsa, E. Yen-Pon, et al.. Synthesis of Aryl-Thioglycopeptides Through Chemoselective Pd-Catalyzed Conjugation. 26th American Peptide Symposium (APS 2019), Jun 2019, Monterey, Californie, United States. ⟨hal-02893419⟩
  • H. Meudal, K. Loth, G. Jousset, V. Aucagne, N. Guyot, et al.. A new structural family for antimicrobial defensins. NMR : a tool for biology XIth, Jan 2019, Paris, France. ⟨hal-02919171⟩
  • S. Abboud, M. Amoura, P. Terrier V., A.F. Delmas, V. Aucagne. N-Hnb-Cys peptide crypto-thioesters: optimized synthetic protocol and second generation device. Noncanonical amino acids (ncAAs): Tools for biological and biophysical investigations, Oct 2019, Paris, France. ⟨hal-02893409⟩
  • S. Abboud, M. Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. An improved synthesis of N-Hnb-Cys peptide crypto-thioesters - studies on the epimerization of cysteine during solid-phase reductive amination. 8th Chemical Protein Synthesis meeting (CPS2019), Jun 2019, Berlin, Germany. ⟨hal-02893426⟩
  • Françoise Paquet, K. Loth, C. Arnoult, V. Aucagne, A.F. Delmas. Spermaurin, a scorpion venom disulfide-rich miniprotein that improves sperm motility and fertilization in mammals.. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02893462⟩
  • F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02893471⟩
  • H. Meudal, N. Guyot, K. Loth, G. Jousset, S. Trapp, et al.. Gga-AvBD11, the archetype of a new structural family of defensins. 21e congrès du Groupe Français des Peptides et des Protéines (GFPP), May 2019, Amboise, France. ⟨hal-02923098⟩
  • H. Meudal, Françoise Paquet, Laurence Jouvensal, V. Aucagne, A.F. Delmas, et al.. Chemical synthesis and natural abundance NMR: an efficient tandem to unravel 3D structures of unlabeled disulfide rich peptides. 21e congrès du Groupe Français des Peptides et des Protéines (GFPP), May 2019, Amboise, France. ⟨hal-02919180⟩
  • J. Diharce, M. Cueto, V. Aucagne, M. Beltramo, P. Bonnet. Fragment covalent docking (FCD) approach: An innovative in silico tools for the prediction of peptide-protein interaction. 256th ACS National Meeting, Aug 2018, Boston, Massachusetts, United States. ⟨hal-02894261⟩
  • M. Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. Second generation N-2-hydroxybenzyl-cysteine peptide crypto-thioesters for native chemical ligation. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02894157⟩
  • S. Abboud, V. Piller, S. Papot, A.F. Delmas, V. Aucagne. Development of chemo-enzymatic methodologies for the total synthesis of proteins through solid-supported chemical ligation. 31e Colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02894152⟩
  • T.M. Vishwanatha, C. Decourt C, V. Robert, M. Galibert, J.-B. Madinier, et al.. Long-lasting increase of gonadotropins by rational design of lipophilic kisspeptin analogs. 2018 International Symposium on Chemical Biology, Jan 2018, Genève, Switzerland. ⟨hal-02894282⟩
  • M. Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation. 4th Belgian Peptide Group Meeting, Feb 2018, Bruxelles, Belgium. ⟨hal-02894279⟩
  • R. Cameron, R. Kirkwood, M. Beltramo, V. Aucagne, A. Tilbrook. A single injection of compound 6 evoked an LH surge and ovulation in 18 week old gilts. 100th annual meeting of the Endocrine Society (ENDO 2018), Mar 2018, Chicago, Illinois,, United States. ⟨hal-02894272⟩
  • T.M. Vishwanatha, C. Decourt, V.P. Terrier, V. Robert, J.-B. Madinier, et al.. Rational design of kisspeptin analogs for the control of the reproductive system. 25th SCT Young Research Fellows meeting, Mar 2018, Orléans, France. ⟨hal-02894277⟩
  • F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02894161⟩
  • M. Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. Design and optimization of alternative thioester precursors to simplify protein synthesis by native chemical ligation. 25th SCT Young Research Fellows meeting, Mar 2018, Orléans, France. ⟨hal-02894273⟩
  • H. Meudal, Laurence Jouvensal, K. Loth, Françoise Paquet, V. Aucagne, et al.. Chemical synthesis and natural abundance NMR: An efficient tandem to unravel 3D structures of Disulfide Rich Miniproteins. 35th European Peptide Symposium, Aug 2018, Dublin, Ireland. ⟨hal-02920483⟩
  • A.F. Delmas, H. Meudal, Laurence Jouvensal, K. Loth, Françoise Paquet, et al.. Chemical synthesis and natural abundance NMR: An efficient tandem to unravel 3D structures of Disulfide Rich Miniproteins. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02920471⟩
  • H. Meudal, Laurence Jouvensal, Françoise Paquet, K. Loth, V. Aucagne, et al.. Chemical synthesis and natural abundance NMR: An efficient tandem to unravel 3D structures of Disulfide Rich Miniproteins. 35th European Peptide Symposium, Aug 2018, Dublin, Ireland. ⟨hal-02919932⟩
  • C. Decourt, V. Robert, D. Lomet, V. Aucagne, M. Beltramo. The kisspeptin analog C6 triggers ovulation in non-breeding ewe in the absence of progestogen priming. 9th International Congress of Neuroendocrinology (ICN 2018), Jul 2018, Toronto, Canada. ⟨hal-02894264⟩
  • Françoise Paquet, H. Meudal, Laurence Jouvensal, K. Loth, V. Aucagne, et al.. Synthèse chimique et RMN en abondance naturelle : un tandem efficace pour résoudre les structures 3D de peptides/protéines riches en ponts disulfure. 5es journées annuelles du GDR MuFoPAM, Oct 2018, Paris, France. ⟨hal-02920025⟩
  • Massimiliano Beltramo, Caroline Decourt, Vincent Robert, Didier Lomet, Vincent Aucagne. In non-breeding ewes the kisspeptin analog c6 triggers ovulation without progestogen priming. 9. International Congress of Neuroendocrinology. ICN2018, Jul 2018, Toronto, Canada. 2018, The 9th International Congress of Neuroendocrinology. Abstract book. ⟨hal-02735160⟩
  • M. Amoura, V.P. Terrier, D. Lelièvre, A.F. Delmas, V. Aucagne. N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation. 25th American Peptide Symposium (APS 25), Jun 2017, Whistler, Canada. ⟨hal-02894293⟩
  • Vincent Robert, Vincent Aucagne, Caroline Decourt, Massimiliano Beltramo. Do endogenous kisspeptins and synthetic agonist C6 trigger different intracellular responses?. 42. Colloque de la Société de Neuroendocrinologie, Sep 2017, Dijon, France. 2017, 42ème Colloque de la Société de Neuroendocrinologie. ⟨hal-02733747⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Vincent Aucagne, Greg Anderson, et al.. Investigation of a kisspeptin analog effects both on synchronization of ovulation and puberty onset in domestic mammals and in rodents. 2. Journées du GdR 3606 Repro, Apr 2017, Tours, France. 75 p., 2017, 2èmes Journées Scientifiques du GdR Repro. ⟨hal-01603310⟩
  • A.F. Delmas, K. Loth, H. Meudal, V.P. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. 20e congrès annuel du Groupe Français des Peptides et des Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02894301⟩
  • M. Amoura, V. P. Terrier, A.F. Delmas, Vincent Aucagne. Second generation N-2-hydroxybenzyl-cysteine peptide crypto-thioesters: achieving very fast NCL kinetics at neutral pH. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02453275⟩
  • Vincent Aucagne, E. Schmitt, P. Bulet, C. Arnoult.. NCL-based total synthesis of spermaurin, a scorpion venom disulfide-rich miniprotein that improves sperm motility and fertilization in mammals. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02453195⟩
  • A. Delmas, K. Loth, H. Meudal, V. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. NMR: a tool for Biology Xth, Jan 2017, Paris, France. ⟨hal-02453460⟩
  • A. Casas-Mora, M. Galibert, A.F. Delmas, V. Aucagne. Design of a New N-Terminal Linker for the Capture-and-Release Purification of Biologically-Relevant Disulfide-Rich Peptides. 25th American Peptide Symposium (APS 25), Jun 2017, Whistler, Canada. ⟨hal-02894295⟩
  • N. J. Stanley, D. Lelièvre, A.F. Delmas, Vincent Aucagne. Development of highly base-labile linkers for the catch-and-release purification of difficult peptides. Application to Avian beta-defensin 2. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02453245⟩
  • C. Decourt, V. Robert, D. Lomet, G. Anderson, Vincent Aucagne, et al.. Pattern of LH secretion after repeated treatment with kisspeptin analog C6 reveals differential sensitivity between mice and ewes. 42e colloque de la société de neuroendocrinologie (SNE 2017), Sep 2017, Dijon, France. ⟨hal-02894288⟩
  • M. Amoura, V.P. Terrier, D. Lelièvre, A.F. Delmas, V. Aucagne. N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation. 7th Chemical Protein Synthesis meeting (CPS 2017), Sep 2017, Haifa, Israel. ⟨hal-02894290⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, A. Delmas, et al.. Investigation of tachyphylaxis of LH response following repeated injections of the kisspeptin analog C6. Colloque International NeuroFrance 2017, May 2017, Bordeaux, France. 2017, Colloque International NeuroFrance 2017. ⟨hal-01605114⟩
  • Agnes Vergnes, Victor P. Terrier, Bressan Albert, Rafael Diego Rosa, Vincent Aucagne, et al.. Laligation native simplifie l’étude de l’activité etdu mécanismed’action des peptides antimicrobiens à multiples domaines :cas des Big défensines d’huître.. IIIèmes journées annuelles MuFoPAM « MultiFonction des Peptides AntiMicrobiens », Oct 2016, Tours, France. ⟨hal-02128427⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, M. Galibert, et al.. Induction of fertile ovulation and puberty advancement by a new kisspeptin analog. 18th International Congress on Animal Reproduction (ICAR), Jun 2016, Tours, France. 676 p., 2016, 18th International Congress on Animal Reproduction (ICAR). ⟨hal-01604087⟩
  • V. P. Terrier, H. Adihou, D. Lelièvre, M. Amoura, A.F. Delmas, et al.. A straightforward strategy for automated Fmoc-based synthesis of peptide “crypto-thioesters”. Application to the total synthesis of biologically-relevant disulfide-rich peptides. Journées de Chimie Organique de la Société Chimique de France (JCO2016), Dec 2016, Palaiseau, France. ⟨hal-02453318⟩
  • A. Casas-Mora, M. Galibert, A.F. Delmas, V. Aucagne. A capture-and-release purification strategy to simplify the synthesis of disulfide-rich peptides. 1st PSL Chemical Biology Meeting, Dec 2016, Paris, France. ⟨hal-02453303⟩
  • A.F. Delmas, V.P. Terrier, R.D. Rosa, A. Bressan, P. Marceau, et al.. Native Chemical ligation simplifies the access of multi-domain antimicrobial peptides: application to the study of big-defensins. 34th European Peptide Symposium 2016 (EPS2016), Sep 2016, Leipzig, Germany. ⟨hal-02895296⟩
  • M. Beltramo, V. Robert, D. Lomet, K. Anger, M. Galibert, et al.. A new selective kisspeptin analog, C6, that advance puberty in mice and stimulate fertile ovulation in ewe. British Society for Neuroendocrinology Annual Meeting, Sep 2016, Glasgow, United Kingdom. ⟨hal-02453336⟩
  • Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, P. Marceau, et al.. Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotropins. 24. Meeting of the American Peptide Society, Jun 2015, Orlando, United States. 2015, 24th Meeting of the American Peptide Society. ⟨hal-02741835⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, Mathieu Galibert, et al.. Induction of synchronized fertile ovulation by a new selective agonist of kisspeptin receptor. 1 Journées du GdR 3606 Repro, Apr 2015, Rennes, France. 105 p., 2015, 1ères Journées Scientifiques du GdR Repro. ⟨hal-02742326⟩
  • Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, P. Marceau, et al.. Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotrophins. 19. Congrès du Groupe Français des Peptides et des Protéines, May 2015, Port-Bail, United States. 2015. ⟨hal-02793091⟩
  • Caroline Decourt, Karine Anger, Vincent Robert, Vincent Aucagne, Mathieu Galibert, et al.. Development of new kisspeptin analogs to stimulate the reproductive system. International Conference on Gonadotropins & Receptors, Sep 2014, Tours, France. 2014, ICGRIII International Conference on Gonadotropins & Receptors. ⟨hal-02744014⟩
  • Massimiliano Beltramo, V. Aucagne, Vincent Robert, M. Galibert, J.B. Madinier, et al.. Design and functional profiling of new KISS1R agonists. 2. Annual Meeting of the GDR RCPG-PhysioMed, Oct 2013, Illkirch, France. 2013, 2nd Annual Meeting of the GDR RCPG-PhysioMed. ⟨hal-02745908⟩
  • Massimiliano Beltramo, V. Aucagne, R. Vincent, M. Galibert, J.B. Madinier, et al.. La kisspeptine : une nouvelle voie pour maitriser l’ovulation chez les petits ruminants ?. 5. Journées d'Animation Scientifique du département Phase (JAS Phase 2013), Oct 2013, Paris, France. 2013. ⟨hal-02805330⟩
  • Mathieu Galibert, Chrystelle Derache, Franck Coste, Hervé Meudal, Anne-Christine Lalmanach, et al.. Improvement of the chemical production of β-defensins including straightforward attribution of disulfide bridges. 18. Réunion du GFPP, May 2013, Sète, France. 1 p., 2013. ⟨hal-02805308⟩
  • M. Galibert, Chrystelle Derache, F. Coste, H. Meudal, Anne-Christine Lalmanach, et al.. Improvement of the chemical production of β-defensins including straighforward attribution of disulfide bridges. 3. International Symposium on Antimicrobial Peptides: Today knowledge and future applications, Jun 2012, Lille, France. pp.C-43, 2012, AMP 2012 - Antimicrobial peptide symposium. ⟨hal-02748134⟩
  • Chrystelle Derache, Emmanuel Kut, Hervé Meudal, Vincent Aucagne, Agnès Delmas, et al.. Antibacterial spectrum of avian defensin 2: peculiarities in relationship with structural features. 3. International Symposium on Antimicrobial Peptides: Today knowledge and future applications (AMP 2012), Jun 2012, Lille, France. pp.D-97, 2012. ⟨hal-02807349⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Anne-Christine Lalmanach, Céline Landon, et al.. Synthesis and oxidative folding of functional miniproteins containing three disulfide bridges. 21e Colloque Biotechnocentre, 2008, Seillac, France. 1 p, 2008. ⟨hal-02818274⟩

Book sections2 documents

  • S. Abboud, A.F. Delmas, V. Aucagne. Solid phase chemical ligation. Brik A., Dawson P., Liu L. Chemical Protein Synthesis, Wiley, In press. ⟨hal-02974365⟩
  • Vincent Aucagne. (9H‐Fluoren‐9‐yl)methanethiol. Encyclopedia of Reagents for Organic Synthesis, John Wiley & Sons, Ltd, 2011, ⟨10.1002/047084289X.rn01287⟩. ⟨hal-02071829⟩

Patents3 documents

  • Nicolas Guyot, Sophie Réhault-Godbert, Anne Silvestre, Sascha Trapp, Sophie Iochmann, et al.. Peptides dérivés d'une beta-défensine 11 aviaire et leurs utilisations. France, N° de brevet: WO 2020/030773 A1. AMV. 2020. ⟨hal-02595638⟩
  • Massimiliano Beltramo, Vincent Aucagne, Alain Caraty, Agnès Delmas, Mathieu Galibert. KISS1R receptor agonist compounds and use thereof for inducing ovulation in mammals. Patent n° : WO2014118318 (A1). 2014, 49 p. + 12 p. annexes. ⟨hal-02793004⟩
  • Massimiliano Beltramo, Vincent Aucagne, Alain Caraty, Agnès Delmas. Composés agonistes du récepteur KISS1R et leur utilisation pour induire l’ovulation chez les mammiféres. N° de brevet: FR3001455 (A1). 2013, 34 p. + 10 p. annexes. ⟨hal-02808772⟩

Preprints, Working Papers, ...1 document

  • Vincent Aucagne, Fabienne Burlina, Oleg Melnyk, Vladimir Torbeev. Des protéines de synthèse taillées sur mesure pour investiguer le vivant. 2020. ⟨hal-02959387⟩