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Catalysis before Enzymes: Thiol-Rich Peptides as Molecular Diversity Providers on the Early Earth

Ibrahim Shalayel , Naoual Leqraa , Veronique Blandin , Yannick Vallée
Diversity, 2023, 15 (2), pp.256. ⟨10.3390/d15020256⟩
Article dans une revue hal-03990636v1

Straightforward Creation of Possibly Prebiotic Complex Mixtures of Thiol-Rich Peptides

Ibrahim Shalayel , Naoual Leqraa , Véronique Blandin , Yannick Vallée
Life, 2023, 13 (4), pp.983. ⟨10.3390/life13040983⟩
Article dans une revue hal-04144825v1

Was methionine the molecular trigger of life on early earth?

Yannick Vallée , Anne Milet , K. V. Raghavendra Rao
Phosphorus, Sulfur, and Silicon and the Related Elements, 2015, 191 (2), pp.329 - 332. ⟨10.1080/10426507.2015.1034314⟩
Article dans une revue hal-01651428v1

Addition of functional vinylzinc reagents to nitrones: synthesis of (E)-N-allylhydroxylamines and their rearrangement into (E)-O-allylhydroxylamines

Pierre Yves Chavant , Shashi Urvish Pandya , Corinne Garçon , Pierre Y. Chavant , Sandrine Py , et al.
Chemical Communications, 2001, 18, pp.1806
Article dans une revue hal-00139506v1
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The Reaction of Aminonitriles with Aminothiols: A Way to Thiol-Containing Peptides and Nitrogen Heterocycles in the Primitive Earth Ocean

Ibrahim Shalayel , Seydou Coulibaly , Kieu Ly , Anne Milet , Yannick Vallée
Artificial Life, 2018, 8 (4), ⟨10.3390/life8040047⟩
Article dans une revue hal-01929877v1

Dialkylzinc-Assisted Alkynylation of Nitrones

Pierre Yves Chavant , Sandra Pinet , Shashi Urvish Pandya , Alexander Ayling , Yannick Vallée
Organic Letters, 2002, 4 (9), pp.1463. ⟨10.1021/ol025618n⟩
Article dans une revue hal-00170491v1

Cysteine Chemistry in Connection with Abiogenesis

Ibrahim Shalayel , Sparta Youssef-Saliba , Fanny Vazart , Cecilia Ceccarelli , Maxime Bridoux , et al.
European Journal of Organic Chemistry, 2020, 2020 (20), pp.3019-3023. ⟨10.1002/ejoc.202000089⟩
Article dans une revue hal-02902426v1

Synthesis of α-oxosulfines by flash vacuum thermolysis of 2,3-dihydro-1,4-oxathin S-oxides. Photoelectron spectrum of thioxoethanal S-oxide.

François Bourdon , Jean Louis Ripoll , Yannick Vallée , Sylvie Lacombe-Lhoste , Genevieve. Pfister-Guillouzo
New Journal of Chemistry, 1991, 15 (Copyright (C) 2017 American Chemical Society (ACS). All Rights Reserved.), pp.533--7
Article dans une revue hal-01587177v1

Theoretical Study, Synthesis, and Reactivity of Five-Membered-Ring Acyl Sulfonium Cations

K. Rao , Nicolas Caiveau , Rolf David , Ibrahim Shalayel , Anne Milet , et al.
European Journal of Organic Chemistry, 2015, 2015 (28), pp.6125 - 6129. ⟨10.1002/ejoc.201500749⟩
Article dans une revue istex hal-01651424v1
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A way to thioacetate esters compatible with non-oxidative prebiotic conditions

Naoual Leqraa , Yvain Nicolet , Anne Milet , Yannick Vallée
Scientific Reports, 2020, 10 (1), pp.14488. ⟨10.1038/s41598-020-71524-7⟩
Article dans une revue hal-02934448v1
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Dimethylzinc-Promoted Vinylation of Nitrones with Pinacol Vinylboronates: a New Access to Allylic N-Hydroxyl Amines.

Shashi U. Pandya , Sandra Pinet , Pierre Yves Chavant , Yannick Vallée
European Journal of Organic Chemistry, 2003, 19, pp.3621. ⟨10.1002/ejoc.200300265⟩
Article dans une revue istex hal-00139505v1

FVT-PES study and reactivity of thionoacrylic compounds

Genevieve Pfister-Guillouzo , Anna Chrostowska , Françoise Gracian , M Khalid , J.L. Ripoll , et al.
New Journal of Chemistry, 1995, 19 (10), pp.1071-1080
Article dans une revue hal-02132326v1

Flash vacuum thermolysis of 2,3-dihydro-1,4-oxathiin: Synthesis, photoelectronic spectroscopy, and dienophilic reactivity of thioxoethanal

F. Bourdon , J.-L. Ripoll , Y. Vallée , Sylvie Lacombe-Lhoste , G. Pfister-Guillouzo
Journal of Organic Chemistry, 1990, 55 (9), pp.2596--2600
Article dans une revue hal-01582250v1

At the very beginning of life on Earth: the thiol-rich peptide (TRP) world hypothesis

Ibrahim Shalayel , Yannick Vallée , Kieu-Dung Ly , K. Rao , Gaël de Paëpe , et al.
International Journal of Developmental Biology, 2017, 61 (8-9), pp.471 - 478. ⟨10.1387/ijdb.170028yv⟩
Article dans une revue hal-01688807v1

Friedel–Crafts reactions of acyl trifluoromethanesulfonates and cyclic acylsulfonium cations generated from acyl fluorides

K.V. Raghavendra Rao , Yannick Vallée
Tetrahedron, 2016, 72 (29), pp.4442 - 4447. ⟨10.1016/j.tet.2016.06.029⟩
Article dans une revue hal-01644650v1

Chemistry of Homocysteine Thiolactone in A Prebiotic Perspective

Ibrahim Shalayel , Yannick Vallée
Life, 2019, 9 (2), pp.40. ⟨10.3390/life9020040⟩
Article dans une revue hal-02902457v1

Theoretical Approach and First Examples of N-Acyl-Thioformamides as Dienophiles in the Diels Alder Reaction

R. Arnaud , P.Y. Chavant , K. Molvinger , Y. Vallée
Journal of the Chemical Society, Chemical Communications, 1995, pp.1897-1898
Article dans une revue hal-01363834v1