Valérie COMPAN

Yvonne Schill, Monika Bijata, Olga Kopach, Volodymyr Cherkas, Dalia Abdel-Galil, et al.. Serotonin 5-HT4 receptor boosts functional maturation of dendritic spines via RhoA-dependent control of F-actin. Communications Biology, Nature Publishing Group, 2020, 3, pp.76. ⟨10.1038/s42003-020-0791-x⟩. ⟨hal-02497383⟩

Alexandra Jean, Laetitia Laurent, Sabira Delaunay, Stéphane Doly, Nicole Dusticier, et al.. Adaptive Control of 5-HT Dorsal Raphe by 5-HT4 in the Prefrontal Cortex Prevents Persistent Hypophagia following Stress. Cell Reports, Elsevier Inc, 2017, 21 (4), pp.901 - 909. ⟨10.1016/j.celrep.2017.10.003⟩. ⟨hal-01825927⟩

Alexandra Jean, Laetitia Laurent, Sabira Delaunay, Stéphane Doly, Nicole Dusticier, et al.. Adaptive Control of Dorsal Raphe by 5-HT4 in the Prefrontal Cortex Prevents Persistent Hypophagia following Stress. Cell Reports, Elsevier Inc, 2017, 21 (4), pp.901-909. ⟨10.1016/j.celrep.2017.10.003⟩. ⟨hal-01667516⟩

Compan Valerie. Serotonin 4 Receptors: A Cornerstone in Anorexia Nervosa?. Autism-Open Access, 2017. ⟨hal-02066694⟩

Valerie Compan. Serotonin 4 Receptors: A Cornerstone in Anorexia Nervosa?. Autism-Open Access, 2017, 07 (02), ⟨10.4172/2165-7890.1000207⟩. ⟨hal-01667528⟩

Valerie Compan. Toggling the serotonin 5-HT 4 receptors between active and silencing state switches motivation from restrictive diet towards overeating. Appetite, Elsevier, 2016, 96, pp.642 - 643. ⟨10.1016/j.appet.2015.08.018⟩. ⟨hal-01667536⟩

J. Amigó, A. Díaz, F. Pilar-Cuéllar, R. Vidal, A. Martín, et al.. The absence of 5-HT4 receptors modulates depression- and anxiety-like responses and influences the response of fluoxetine in olfactory bulbectomised mice: Adaptive changes in hippocampal neuroplasticity markers and 5-HT1A autoreceptor. Neuropharmacology, Elsevier, 2016, 111, pp.47 - 58. ⟨10.1016/j.neuropharm.2016.08.037⟩. ⟨hal-01667532⟩

Valerie Compan, B. T. Walsh, W. Kaye, A. Geliebter. How Does the Brain Implement Adaptive Decision Making to Eat?. Journal of Neuroscience, Society for Neuroscience, 2015, 35 (41), pp.13868 - 13878. ⟨10.1523/JNEUROSCI.2602-15.2015⟩. ⟨hal-01667540⟩

Lisa Dupont, Ken R. Bracke, Joris H. de Maeyer, Valerie Compan, Guy F. Joos, et al.. Investigation of 5-HT4 receptors in bronchial hyperresponsiveness in cigarette smoke-exposed mice. Pulmonary Pharmacology & Therapeutics, 2014, 28 (1), pp.60 - 67. ⟨10.1016/j.pupt.2013.10.003⟩. ⟨hal-01667544⟩

Valerie Compan. Under- to over-eating: how do serotonin receptors contribute?. Future Neurology, Future Medicine, 2013, 8 (6), pp.701 - 714. ⟨10.2217/fnl.13.54⟩. ⟨hal-01671470⟩

Valerie Compan. Under- to over-eating: how do serotonin receptors contribute?. Future Neurology, Future Medicine, 2013, 8 (6), pp.701 - 714. ⟨10.2217/fnl.13.54⟩. ⟨hal-01667559⟩

Valerie Compan, Laetitia Laurent, Alexandra Jean, Céline Macary, Joël Bockaert, et al.. Serotonin signaling in eating disorders. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, Wiley, 2012, 1 (6), pp.715 - 729. ⟨10.1002/wmts.45⟩. ⟨hal-01667586⟩

Cecilia Ratner, Anders Ettrup, Marco Bueter, Mette E. Haahr, Valerie Compan, et al.. Cerebral Markers of the Serotonergic System in Rat Models of Obesity and After Roux-en-Y Gastric Bypass. Obesity, Wiley, 2012, 20 (10), pp.2133 - 2141. ⟨10.1038/oby.2012.75⟩. ⟨hal-01667579⟩

A. Jean, L. Laurent, J. Bockaert, Y. Charnay, N. Dusticier, et al.. The nucleus accumbens 5-HTR₄-CART pathway ties anorexia to hyperactivity.. Translational Psychiatry, Nature Pub. Group, 2012, 2, pp.e203. ⟨10.1038/tp.2012.131⟩. ⟨hal-00843338⟩

A. Jean, L Laurent, J. Bockaert, Y Charnay, N. Dusticier, et al.. The nucleus accumbens 5-HTR4-CART pathway ties anorexia to hyperactivity. Translational Psychiatry, Nature Pub. Group, 2012, 2 (12), ⟨10.1038/tp.2012.131⟩. ⟨hal-01667570⟩

Joël Bockaert, Sylvie Claeysen, Valerie Compan, Aline Dumuis. 5-HT4 receptors, a place in the sun: act two. Current Opinion in Pharmacology, Elsevier, 2011, 11 (1), pp.87-93. ⟨10.1016/j.coph.2011.01.012⟩. ⟨hal-01667589⟩

Luis Segu, Marie-José Lecomte, Mathieu Wolff, Julie Santamaria, René Hen, et al.. Hyperfunction of Muscarinic Receptor Maintains Long-Term Memory in 5-HT4 Receptor Knock-Out Mice. PLoS ONE, Public Library of Science, 2010, 5 (3), pp.e9529. ⟨10.1371/journal.pone.0009529⟩. ⟨hal-01667595⟩

Christine Manrique, Valerie Compan, Céline Rosselet, Sylvie Gustave Dit Duflo. Specific knock-down of GAD67 in the striatum using naked small interfering RNAs. African Journal of Biotechnology, Academic Journals, 2009, 142 (3-4), pp.185 - 192. ⟨10.1016/j.jbiotec.2009.05.009⟩. ⟨hal-01667602⟩

Gérard Alonso, Evelyne Galibert, Véra Boulay, Anne Duvoid-Guillou, Alexandra Jean, et al.. Sustained Elevated Levels of Circulating Vasopressin Selectively Stimulate the Proliferation of Kidney Tubular Cells via the Activation of V 2 Receptors. Endocrinology, Endocrine Society, 2009, 150 (1), pp.239-250. ⟨10.1210/en.2008-0068⟩. ⟨hal-01667647⟩

Karine Toupet, Valerie Compan, Carole Crozet, Chantal Mourton-Gilles, Nadine Mestre-Francés, et al.. Effective Gene Therapy in a Mouse Model of Prion Diseases. PLoS ONE, Public Library of Science, 2008, 3 (7), pp.e2773. ⟨10.1371/journal.pone.0002773⟩. ⟨hal-01667611⟩

Joël Bockaert, Sylvie Claeysen, Valerie Compan, Aline Dumuis. 5-HT4 receptors: History, molecular pharmacology and brain functions. Neuropharmacology, Elsevier, 2008, 55 (6), pp.922-931. ⟨10.1016/j.neuropharm.2008.05.013⟩. ⟨hal-01667629⟩

Leonie Welberg, Alexandra Jean, Grégory Conductier, Christine Manrique, Constantin Bouras, et al.. Systems Neuroscience: No food in the CART. Nature Reviews Neuroscience, Nature Publishing Group, 2007, 8 (11), pp.814 - 815. ⟨10.1038/nrn2266⟩. ⟨hal-01667687⟩

Alexandra Jean, Grégory Conductier, C. Manrique, C. Bouras, P. Berta, et al.. Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2007, 104 (41), pp.16335 - 16340. ⟨10.1073/pnas.0701471104⟩. ⟨hal-01667673⟩

Patrick Keller, Valerie Compan, Joël Bockaert, Jean-Paul Giacobino, Yves Charnay, et al.. Characterization and localization of cocaine- and amphetamine-regulated transcript (CART) binding sites. Peptides, Elsevier, 2006, 27 (6), pp.1328 - 1334. ⟨10.1016/j.peptides.2005.10.016⟩. ⟨hal-01667693⟩

G. Conductier, N. Dusticier, G. Lucas, F. Côté, G. Debonnel, et al.. Adaptive changes in serotonin neurons of the raphe nuclei in 5-HT4 receptor knock-out mouse. European Journal of Neuroscience, Wiley, 2006, 24, pp.1053-1062. ⟨hal-00117039⟩

Grégory Conductier, Nicole Dusticier, Guillaume Lucas, Francine Cote, Guy Debonnel, et al.. Adaptive changes in serotonin neurons of the raphe nuclei in 5-HT(4) receptor knock-out mouse. European Journal of Neuroscience, Wiley, 2006, 24 (4), pp.1053-1062. ⟨10.1111/j.1460-9568.2006.04943.x⟩. ⟨inserm-00091312⟩

Guillaume Lucas, Valerie Compan, Yves Charnay, Rachael L. Neve, Eric J. Nestler, et al.. Frontocortical 5-HT4 receptors exert positive feedback on serotonergic activity: Viral transfections, subacute and chronic treatments with 5-HT4 agonists. Biological Psychiatry, Elsevier, 2005, 57 (8), pp.918 - 925. ⟨10.1016/j.biopsych.2004.12.023⟩. ⟨hal-01667726⟩

G. Lucas, V. Compan, Y. Charnay, R.L. Neve, E.J. Nestler, et al.. Frontocortical 5-HT4 receptors exert positive feedback on serotonergic activity: viral transfections, subacute and chronic treatments with 5-HT4 agonists. Biological Psychiatry, Elsevier, 2005, 57 (8), pp.918-925. ⟨hal-00143232⟩

Grégory Conductier, Cyril Crosson, René Hen, Joël Bockaert, Valerie Compan. 3,4-N-Methlenedioxymethamphetamine-Induced Hypophagia is Maintained in 5-HT1B Receptor Knockout Mice, but Suppressed by the 5-HT2C Receptor Antagonist RS102221. Neuropsychopharmacology, Nature Publishing Group, 2005, 30 (6), pp.1056 - 1063. ⟨10.1038/sj.npp.1300662⟩. ⟨hal-01667702⟩

Joël Bockaert, S. Claeysen, Valerie Compan, Aline Dumuis. 5-HT4 receptors. Current Drug Targets -CNS and Neurological Disorders-, Bentham Science Publishers, 2004, 3 (1), pp.39-51. ⟨10.2174/1568007043482615⟩. ⟨hal-01667891⟩

V. Compan, Y. Charnay, N. Dusticier, A. Daszuta, R. Hen, et al.. [Feeding disorders in 5-HT4 receptor knockout mice]. J. Soc Biol, 2004, 198, pp.37-49. ⟨hal-00306826⟩

Valerie Compan, Yves Charnay, Nicole Dusticier, Annie Daszuta, René Hen, et al.. [Feeding disorders in 5-HT4 receptor knockout mice].. Journal- Societe de Biologie, Paris : Société de biologie, 2004, 198 (1), pp.37-49. ⟨hal-01667871⟩

Valerie Compan, Mingming Zhou, Régis Grailhe, Russell A. Gazzara, Renee Martin, et al.. Attenuated Response to Stress and Novelty and Hypersensitivity to Seizures in 5-HT4 Receptor Knock-Out Mice. Journal of Neuroscience, Society for Neuroscience, 2004, 24 (2), pp.412 - 419. ⟨10.1523/JNEUROSCI.2806-03.2004⟩. ⟨hal-01667757⟩

V. Compan, K. Scearce-Levie, C. Crosson, A. Daszuta, R. Hen. Enkephalin contributes to the locomotor stimulating effects of 3,4-methylenedioxy-N-methylamphetamine. European Journal of Neuroscience, Wiley, 2003, 18, pp.383-390. ⟨hal-00306953⟩

Valerie Compan, K. Scearce-Levie, C. Crosson, A. Daszuta, R. Hen. Enkephalin contributes to the locomotor stimulating effects of 3,4-methylenedioxy-N-methylamphetamine. European Journal of Neuroscience, Wiley, 2003, 18 (2), pp.383 - 390. ⟨10.1046/j.1460-9568.2003.02767.x⟩. ⟨hal-01667764⟩

X. Zhuang, Cornelius Gross, Luca Santarelli, Valerie Compan, Anne-Cecile Trillat, et al.. Altered Emotional States in Knockout Mice Lacking 5-HT1A or 5-HT1B Receptors. Neuropsychopharmacology, Nature Publishing Group, 1999, 21 (2), pp.52S - 60S. ⟨10.1016/S0893-133X(99)00047-0⟩. ⟨hal-01667782⟩

Valerie Compan, L Segu, M C Buhot, A. Daszuta. Differential effects of serotonin (5-HT) lesions and synthesis blockade on neuropeptide-Y immunoreactivity and 5-HT1A, 5-HT1B/1D and 5-HT2A/2C receptor binding sites in the rat cerebral cortex.. Brain Research, Elsevier, 1998, pp.264-76. ⟨hal-01667811⟩

Valerie Compan, L Segu, M C Buhot, A. Daszuta. Selective increases in serotonin 5-HT1B/1D and 5-HT2A/2C binding sites in adult rat basal ganglia following lesions of serotonergic neurons.. Brain Research, Elsevier, 1998, pp.103-11. ⟨hal-01667818⟩

Valerie Compan, P. Salin, A. Daszuta. Selective effects of partial and severe lesions of the serotonergic systems on Met-enkephalin and substance P neurons in rat basal ganglia.. Molecular Brain Research, Elsevier, 1997, pp.246-56. ⟨hal-01667825⟩

Valerie Compan, N. Dusticier, A. Nieoullon, A. Daszuta, V. Compan. Opposite changes in striatal neuropeptide Y immunoreactivity after partial and complete serotonergic depletion in the rat. Synapse, Wiley-Blackwell, 1996, 24 (1), pp.87 - 96. ⟨10.1002/(SICI)1098-2396(199609)24:1<87::AID-SYN9>3.0.CO;2-C⟩. ⟨hal-01667865⟩

Valerie Compan, A. Daszuta, P. Salin, M Sebben, J. Bockaert, et al.. Lesion study of the distribution of serotonin 5-HT4 receptors in rat basal ganglia and hippocampus.. Supplement .. to the European journal of neuroscience., 1996, pp.2591-8. ⟨hal-01667869⟩

Compan Valerie. 2nd Global Conference on Obesity Treatment and Weight Management. 15th Benjamin Franklin Lafayette Seminar, 2017, Frejus, France. ⟨hal-01670970⟩

Valerie Compan, O. Aribo, L. Laurent, G. Conductier., R. Maldonado. Neural underpinnings of excessive intake of cocaine and food can be different.. 47ème Annual Meeting, SFN, 2017, Washington, United States. ⟨hal-01670971⟩

Compan Valerie. How does the brain implement decision-making to eat. Implication of the serotonin 4 receptors.. 2nd Global Conference on Obesity Treatment and Weight Management, 2016, Las Vegas, United States. ⟨hal-01670968⟩

Compan Valerie. The switch from anorexia to cocaine or food abuse involves the serotonin 4 receptors. . 45ème Annual Meeting, SFN, 2015, Chicago, United States. ⟨hal-01670952⟩

Compan Valerie. Absence of hypophagia and enhanced glucocorticoid receptor negative feedback in serotonin 4 receptors knockout female mice. . 14th Benjamin Franklin Seminars, 2015, Frejus, France. ⟨hal-01670966⟩

Compan Valerie. Selecting one’s addiction to cocaine, anorexia or food depends on the activity state of serotonin 4 receptors. 11th International Society for Serotonin Research Meeting, 2014, Arabella, South Africa. ⟨hal-01670948⟩

Compan Valerie. Involvement of the serotonin system in eating disorders. . 11ème colloque. Société Neurosciences Françaises, 2013, Lyon, France. ⟨hal-01670930⟩

Compan Valerie. Serotonin 4 receptors / CART pathway ties anorexia to motor hyperactivity. . 11ème colloque. Société Neurosciences Françaises, 2013, Lyon, France. ⟨hal-01670931⟩

Compan Valerie. Serotonin 4 receptors cause hypophagia induced by stress.. 13th Benjamin Franklin Seminars, 2013, Fréjus, France. ⟨hal-01670933⟩

Compan Valerie. Toggling serotonin 4 receptors signaling pathway in the nucleus accumbens provoked anorexia to binge-type eating. . 15th International Neurosciences Winter Conferences, 2013, Soelden, Austria. ⟨hal-01670946⟩

M. Pratlong, L. Laurent, Boussadia. P., Valerie Compan. Anorexia depends on the AKAP/PKA complex under the influence of serotonin 4 receptors in the nucleus accumbens. . 42ème Annual Meeting, SFN, 2012, New-Orleans, United States. ⟨hal-01670904⟩

L. Laurent, Valerie Compan. Basculer les récepteurs cérébraux 5-HT4 de la sérotonine d’un état actif à inactif commute la motivation à se dénutrir vers la suralimentation. . Association francophone pour le savoir, 80ème congrès de ACFAS, 2012, Montréal, Canada. ⟨hal-01670928⟩

M. Pratlong, L. Laurent, A. Jean, G. Gastaldi, C. Jung, et al.. Serotonin 5-HT4 receptors are involved in the regulation of stress axis. 41ème Annual Meeting, Society for Neuroscience, 2011, Washington, United States. ⟨hal-01670796⟩

Compan Valerie. A rewarding homeostatic paradoxical association of anorexia and hyperactivity depends on serotonin 4 receptors in the nucleus accumbens. . 12th Benjamin Franklin Lafayette Seminar, 2011, Fréjus, France. ⟨hal-01670799⟩

M. Pratlong, L. Laurent, A. Jean, G. Gastaldi, C. Jung, et al.. Serotonin 5-HT4 receptors are involved in the regulation of stress axis.. 41ème Annual Meeting, SFN, 2011, Washington, United States. ⟨hal-01670805⟩

O. Aribo, L. Laurent, V. Mendizabal, A. Jean, R. Maldonado, et al.. 5-HT4 receptors trigger adaptive mechanisms to limit cocaine reward.. 9th Serotonin Club Meeting, 2010, Québec, Canada. ⟨hal-01670791⟩

Compan Valerie. Un cerveau sans appétit: une nouvelle dépendance ?. 2ème Meeting sur le dépistage et la prise en charge des patients atteints de troubles des conduites alimentaires, 2009, NIMES, France. ⟨hal-01670781⟩

Valerie Compan, A. Jean, G. Conductier, C. Manrique, R. Hen, et al.. Anorexia and ecstasy share pathways: Serotonin 5-HT4 receptors and CART in the nucleus accumbens. 8th Meeting de la Société des Neurosciences Françaises, 2009, Bordeaux, France. ⟨hal-01670774⟩

A. Jean, Compan Valerie. Ecstasy suppresses appetite through a 5-HT4 receptor dependent CART expression in the nucleus accumbens.. 8th Serotonin Club Meeting, Keble College, 2008, Oxford, United Kingdom. ⟨hal-01670768⟩

Compan Valerie. Quelques apports de la neurobiologie pour identifier une nouvelle dépendance : l'anorexie. . Société de Biologie de Montpellier, 2008, Montpellier, France. ⟨hal-01670777⟩

Valerie Compan. Identification du premier exemple d'un gène impliqué dans l'influence du stress sur l'anorexie. . 23ème congrès de la Société Française d’Endocrinologie, 2006, Montpellier, France. ⟨hal-01670758⟩

Valerie Compan. Ecstasie, comportement alimentaire et pathologies du contrôle central de la prise alimentaire. 2ème colloque de Méditérranéen de Neurosciences, 2006, Marrakech, Maroc. ⟨hal-01670763⟩

Valerie Compan. Qu'apportent les souris knock-out à la connaissance des implications physiologiques et physiopathologiques de la sérotonine ? . Société de Biologie de Paris, 2003, Paris, France. ⟨hal-01670750⟩

Valerie Compan. Proposition d’un projet pédagogique en vue de l’insertion professionnelle des Docteurs des Universités Européennes. Exemple de transferts de Technologies. . 3ième Rencontres Méditerranéennes des Biotechnologies, 2003, NIMES, France. ⟨hal-01670753⟩

Valerie Compan, M. Zhou, D. Brunner, R. Grailhe, J. Gingrich, et al.. Serotonin receptor 4 knockout mice exhibit hyposensitivity to stressors. . 32th Annual Meeting, Society for Neuroscience, 2002, Orlando, United States. ⟨hal-01670746⟩

A. Nieoullon, D. Hajji, P. Salin, L. Kerkerian-Le Goff, Valerie Compan, et al.. Looking for the cellular basis of neuroplasticity in the adult brain : adaptative change in the peptidergic neurons at striatal level in the rat following impairment of dopaminergic nigrostriatal and corticostriatal transmission.The 2d SONA, Society of Neuroscientists of Africa ». The 2d SONA, Society of Neuroscientists of Africa », 1995, Marrakech, Morocco. ⟨hal-01670741⟩

Compan Valerie. Serotonin in eating disorders. Handbook of the Behavioral Neurobiology of Serotonin (2nd ed), In press. ⟨hal-02066225⟩

Laetitia Laurent, Alexandra Jean, Christine Manrique, Mohamed Najimi, Fatiha Chigr, et al.. Anorexia and drugs of abuse abnormally suppress appetite, the result of a shared molecular signal foul-up.. Animal model of eating disorders book, SPRINGER SCIENCE & BUSINESS MEDIA, 2012. ⟨hal-01668023⟩

Joël Bockaert, Sylvie Claeysen, Valerie Compan, Aline Dumuis. Les récepteurs 5-HT4 : 20 ans déjà ! / Les récepteurs sérotoninergiques 5-HT4. Sérotonine - Aspects biologiques et cliniques, 2012, 978-2-257-20509-4. ⟨hal-01667922⟩

Valerie Compan. À la limite des capacités d’adaptation des neurones sérotonergiques : l’anorexie, une nouvelle dépendance.. La sérotonine, LAVOISIER, 2010. ⟨hal-01668015⟩

Valerie Compan. Do limits of Neuronal Plasticity Represent an Opportunity for Mental Diseases, Such as Addiction to Food and Illegal Drugs? Use and Utilities of Serotonin Receptor Knock-Out Mice. SEROTONIN RECEPTORS IN NEUROBIOLOGY, 2007. ⟨hal-01667664⟩

Valerie Compan. A propos de la ritaline. Approches des troubles du comportement. L’enfance et l’adolescence par gros temps., Le Sociographe, Thétète/Champ Social, 2006. ⟨hal-01667909⟩

Valerie Compan, A. Afonso. Proposition d’un modèle d’étude des pathologies alimentaires : le support neurobiologique des addictions aux drogues ou aux aliments (boulimie, anorexie) après stress peut-il être identique ?. Neurobiologie et Addictions., BELIN, 2006, SUP PSYCHOLOGIE. ⟨hal-01667901⟩