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Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation

Muhammad Ahmad Maqbool , Léo Pioger , Amal Zine El Aabidine , Nezih Karasu , Anne Marie Molitor , et al.
Cell Reports, 2020, 32, ⟨10.1016/j.celrep.2020.108048⟩
Article dans une revue hal-03015018v1
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Short tandem repeats are important contributors to silencer elements in T cells

Saadat Hussain , Nori Sadouni , Dominic van Essen , Lan T M Dao , Quentin Ferré , et al.
Nucleic Acids Research, 2023, 51 (10), pp.4845-4866. ⟨10.1093/nar/gkad187⟩
Article dans une revue hal-04044391v1
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Defining Functionally Relevant Spatial Chromatin Domains: It is a TAD Complicated

Natalia Sikorska , Tom Sexton
Journal of Molecular Biology, 2020, 432, pp.653 - 664. ⟨10.1016/j.jmb.2019.12.006⟩
Article dans une revue hal-03489556v1

Assessment of 3D Interactions Between Promoters and Distal Regulatory Elements with Promoter Capture Hi-C (PCHi-C)

Nezih Karasu , Thomas Sexton
Methods in Molecular Biology, 2021, 2351, pp.229-248. ⟨10.1007/978-1-0716-1597-3_13⟩
Article dans une revue hal-03708078v1
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Dissecting Gene Repression: Not Just Location, Location, Location

Tom Sexton
Trends in Cell Biology, 2019, 29, pp.605 - 607. ⟨10.1016/j.tcb.2019.06.001⟩
Article dans une revue hal-03487957v1

4C-Seq: Interrogating Chromatin Looping with Circular Chromosome Conformation Capture

Nezih Karasu , Thomas Sexton
Methods in Molecular Biology, 2021, 2157, pp.19-34. ⟨10.1007/978-1-0716-0664-3_3⟩
Article dans une revue hal-03708074v1
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Context-dependent transcriptional remodeling of TADs during differentiation

Sanjay Chahar , Yousra Ben Zouari , Hossein Salari , Anne Molitor , Dominique Kobi , et al.
2022
Pré-publication, Document de travail hal-03797986v1
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ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C

Yousra Ben Zouari , Anne M Molitor , Natalia Sikorska , Vera Pancaldi , Tom Sexton
Genome Biology, 2019, 20 (1), pp.102. ⟨10.1186/s13059-019-1706-3⟩
Article dans une revue hal-04083921v1
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Precise measurements of chromatin diffusion dynamics by modeling using Gaussian processes

Guilherme Monteiro Oliveira , Attila Oravec , Dominique Kobi , Manon Maroquenne , Kerstin Bystricky , et al.
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-26466-7⟩
Article dans une revue hal-03709399v1
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Distinct polymer physics principles govern chromatin dynamics in mouse and Drosophila topological domains

Vuthy Ea , Tom Sexton , Thierry Gostan , Laurie Herviou , Marie-Odile Baudement , et al.
BMC Genomics, 2015, 16, pp.607. ⟨10.1186/s12864-015-1786-8⟩
Article dans une revue hal-01212952v1

Detecting Spatial Chromatin Organization by Chromosome Conformation Capture II: Genome-Wide Profiling by Hi-C

Matteo Viettri Rudan , Suzana Hadjur , Thomas Sexton
Methods in Molecular Biology, 2017, 1589, pp.47-74. ⟨10.1007/7651_2015_261⟩
Article dans une revue hal-03676440v1
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TADs are 3D structural units of higher-order chromosome organization in Drosophila

Quentin Szabo , Daniel Jost , Jia-Ming Chang , Diego Cattoni , Giorgio Papadopoulos , et al.
Science Advances , 2018, 4 (2), pp.eaar8082. ⟨10.1126/sciadv.aar8082⟩
Article dans une revue hal-01726709v1
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Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington’s disease mice

Rafael Alcalá-Vida , Jonathan Seguin , Caroline Lotz , Anne Molitor , Ibai Irastorza-Azcarate , et al.
Nature Communications, 2021, 12 (1), pp.364. ⟨10.1038/s41467-020-20605-2⟩
Article dans une revue cea-03428640v1
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Myod1 and GR coordinate myofiber-specific transcriptional enhancers

Daniela Rovito , Anna-Isavella Rerra , Vanessa Ueberschlag-Pitiot , Shilpy Joshi , Nezih Karasu , et al.
Nucleic Acids Research, 2021, 49 (8), pp.4472 - 4492. ⟨10.1093/nar/gkab226⟩
Article dans une revue hal-03251776v1

4See: A Flexible Browser to Explore 4C Data

Yousra Ben Zouari , Angeliki Platania , Anne Molitor , Tom Sexton
Frontiers in Genetics, 2019, 10, ⟨10.3389/fgene.2019.01372⟩
Article dans une revue hal-03676444v1
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Global chromatin conformation differences in the Drosophila dosage compensated chromosome X

Koustav Pal , Mattia Forcato , Daniel Jost , Thomas Sexton , Cédric Vaillant , et al.
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-13350-8⟩
Article dans une revue hal-02386022v1
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Competition between transcription and loop extrusion modulates promoter and enhancer dynamics

Angeliki Platania , Cathie Erb , Mariano Barbieri , Bastien Molcrette , Erwan Grandgirard , et al.
2023
Pré-publication, Document de travail hal-04312310v1
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Concurrent CDX2 cis -deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL

Marie Passet , Rathana Kim , Stéphanie Gachet , François Sigaux , Julie Chaumeil , et al.
Blood, 2022, 139 (24), pp.3505-3518. ⟨10.1182/blood.2021014723⟩
Article dans une revue hal-03788702v1
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Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene

Jaafar Alomairi , Anne Molitor , Nori Sadouni , Saadat Hussain , Magali Torres , et al.
PLoS ONE, 2020, 15 (5), pp.e0233191. ⟨10.1371/journal.pone.0233191⟩
Article dans une revue hal-02773600v1

Chromosome topology guides the Drosophila Dosage Compensation Complex for target gene activation

Tamás Schauer , Yad Ghavi-Helm , Tom Sexton , Christian Albig , Catherine Regnard , et al.
EMBO Reports, 2017, 18 (10), pp.1854-1868. ⟨10.15252/embr.201744292⟩
Article dans une revue hal-02047582v1
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Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions

Diego Cattoni , Andrés M Cardozo Gizzi , Mariya Georgieva , Marco Di Stefano , Alessandro Valeri , et al.
Nature Communications, 2017, 8 (1), pp.1753. ⟨10.1038/s41467-017-01962-x⟩
Article dans une revue hal-01652403v1
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The histone variant macroH2A1.1 regulates RNA polymerase II-paused genes within defined chromatin interaction landscapes

Ludmila Recoules , Alexandre Heurteau , Flavien Raynal , Nezih Karasu , Fatima Moutahir , et al.
Journal of Cell Science, 2022, 135 (7), pp.jcs259456. ⟨10.1242/jcs.259456⟩
Article dans une revue hal-03798057v1