Recherche - Archive ouverte HAL Accéder directement au contenu

Filtrer vos résultats

16 résultats
Image document

Modeling the influence of DNA lesion on the regulation of gene expression

Tom Miclot
Organic chemistry. Université de Lorraine; Università degli studi (Palerme, Italie), 2022. English. ⟨NNT : 2022LORR0256⟩
Thèse tel-04192802v1

Predicting the three-dimensional structure of the c-KIT proto-oncogene promoter and the dynamics of its strongly coupled guanine quadruplexes

Emmanuelle Bignon , Angelo Spinello , Tom Miclot , Luisa D’anna , Cosimo Ducani , et al.
Journal of Physical Chemistry Letters, 2023, 14 (20), pp.4704-4710. ⟨10.1021/acs.jpclett.3c00765⟩
Article dans une revue hal-04258965v1

G‐quadruplex recognition by DARPIns through epitope/paratope analogy

Tom Miclot , Emmanuelle Bignon , Alessio Terenzi , Stéphanie Grandemange , Giampaolo Barone , et al.
Chemistry - A European Journal, 2022, 28 (57), pp.e202201824. ⟨10.1002/chem.202201824⟩
Article dans une revue hal-03925664v1

How Fragile We Are: Influence of Stimulator of Interferon Genes (STING) Variants on Pathogen Recognition and Immune Response Efficiency

Jeremy Morere , Cécilia Hognon , Tom Miclot , Tao Jiang , Elise Dumont , et al.
Journal of Chemical Information and Modeling, 2022, 62 (12), pp.3096-3106. ⟨10.1021/acs.jcim.2c00315⟩
Article dans une revue hal-04157319v1

Forever young: Structural stability of telomeric guanine quadruplexes in the presence of oxidative DNA lesions

Tom Miclot , Camille Corbier , Alessio Terenzi , Cécilia Hognon , Stéphanie Grandemange , et al.
Chemistry - A European Journal, 2021, 27 (34), pp.8865-8874. ⟨10.1002/chem.202100993⟩
Article dans une revue hal-03503711v1

Resolving a guanine-quadruplex structure in the SARS-CoV-2 genome through circular dichroism and multiscale molecular modeling

Luisa d'Anna , Tom Miclot , Emmanuelle Bignon , Ugo Perricone , Giampaolo Barone , et al.
Chemical Science, 2023, 14 (41), pp.11332-11339. ⟨10.1039/d3sc04004f⟩
Article dans une revue hal-04487444v1

Microscopic interactions between ivermectin and key human and viral proteins involved in SARS-CoV-2 infection

Antonio Francés-Monerris , Cristina García-Iriepa , Isabel Iriepa , Cécilia Hognon , Tom Miclot , et al.
Physical Chemistry Chemical Physics, 2021, 23 (40), pp.22957-22971. ⟨10.1039/D1CP02967C⟩
Article dans une revue hal-03753387v1

Thermodynamics of the Interaction between the Spike Protein of Severe Acute Respiratory Syndrome Coronavirus-2 and the Receptor of Human Angiotensin-Converting Enzyme 2. Effects of Possible Ligands

Cristina García-Iriepa , Cécilia Hognon , Antonio Francés-Monerris , Isabel Iriepa , Tom Miclot , et al.
Journal of Physical Chemistry Letters, 2020, 11 (21), pp.9272-9281. ⟨10.1021/acs.jpclett.0c02203⟩
Article dans une revue hal-04157339v1

Structure and Dynamics of RNA Guanine Quadruplexes in SARS-CoV-2 Genome. Original Strategies against Emerging Viruses

Tom Miclot , Cécilia Hognon , Emmanuelle Bignon , Alessio Terenzi , Marco Marazzi , et al.
Journal of Physical Chemistry Letters, 2021, 12 (42), pp.10277--10283. ⟨10.1021/acs.jpclett.1c03071⟩
Article dans une revue hal-03786805v1

Structure of the 5′ untranslated region in SARS-CoV-2 genome and its specific recognition by innate immune system via the human oligoadenylate synthase 1

Emmanuelle Bignon , Tom Miclot , Alessio Terenzi , Giampaolo Barone , Antonio Monari
Chemical Communications, 2022, 58 (13), pp.2176-2179. ⟨10.1039/D1CC07006A⟩
Article dans une revue hal-04487446v1

Role of RNA guanine quadruplexes in favoring the dimerization of SARS unique domain in coronaviruses

Cécilia Hognon , Tom Miclot , Cristina García-Iriepa , Antonio Francés-Monerris , Stéphanie Grandemange , et al.
Journal of Physical Chemistry Letters, 2020, 11 (14), pp.5661-5667. ⟨10.1021/acs.jpclett.0c01097⟩
Article dans une revue hal-02912974v1

Mechanism of the covalent inhibition of human transmembrane protease serine 2 as an original antiviral strategy

Angelo Spinello , Luisa D’anna , Emmanuelle Bignon , Tom Miclot , Stéphanie Grandemange , et al.
Journal of Physical Chemistry B, 2023, 127 (28), pp.6287-6295. ⟨10.1021/acs.jpcb.3c02910⟩
Article dans une revue hal-04258941v1

Understanding the interactions of Guanine‐Quadruplexes with peptides as novel strategies for diagnosis or tuning biological functions

Tom Miclot , Aurane Froux , Luisa d’Anna , Emmanuelle Bignon , Stéphanie Grandemange , et al.
ChemBioChem, 2023, 24 (6), pp.e202200624. ⟨10.1002/cbic.202200624⟩
Article dans une revue hal-03925526v1
Image document

Never cared for what they do: High structural stability of Guanine-Quadruplexes in the presence of strand-break damage

Tom Miclot , Cécilia Hognon , Emmanuelle Bignon , Alessio Terenzi , Stéphanie Grandemange , et al.
Molecules, 2022, 27 (10), pp.3256. ⟨10.3390/molecules27103256⟩
Article dans une revue hal-03925687v1

Specific Recognition of the 5′-Untranslated Region of West Nile Virus Genome by Human Innate Immune System

Emmanuelle Bignon , Marco Marazzi , Tom Miclot , Giampaolo Barone , Antonio Monari
Viruses, 2022, 14 (6), pp.1282. ⟨10.3390/v14061282⟩
Article dans une revue hal-04487450v1

Molecular basis of SARS-CoV-2 infection and rational design of potential antiviral agents: Modeling and simulation approaches

Antonio Francés-Monerris , Cécilia Hognon , Tom Miclot , Cristina García-Iriepa , Isabel Iriepa , et al.
Journal of Proteome Research, 2020, 19 (11), pp.4291-4315. ⟨10.1021/acs.jproteome.0c00779⟩
Article dans une revue hal-03503722v1