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NF-κB–dependent IRF1 activation programs cDC1 dendritic cells to drive antitumor immunity

Ghita Ghislat , Ammar Cheema , Elodie Baudoin , Christophe Verthuy , Pedro Ballester , et al.
Science Immunology, 2021, 6 (61), pp.eabg3570. ⟨10.1126/sciimmunol.abg3570⟩
Article dans une revue hal-03329415v1

Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes

Rongrong Fan , Amine Toubal , Saioa Goni , Karima Drareni , Zhiqiang Huang , et al.
Nature Medicine, 2016, 22 (7), pp.780-791. ⟨10.1038/nm.4114⟩
Article dans une revue hal-01438151v1

GADD45 beta Loss Ablates Innate Immunosuppression in Cancer

Daniela Verzella , Jason Bennett , Mariafausta Fischietti , Anil K. Thotakura , Camilla Recordati , et al.
Cancer Research, 2018, 78 (5), pp.1275-1292. ⟨10.1158/0008-5472.CAN-17-1833⟩
Article dans une revue hal-02118047v1
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Soluble ectodomain CD163 and extracellular vesicle-associated CD163 are two differently regulated forms of `soluble CD163' in plasma

Anders Etzerodt , Ronan M. G. Berg , Ronni R. Plovsing , Morten N. Andersen , Magali Bebien , et al.
Scientific Reports, 2017, 7, pp.40286. ⟨10.1038/srep40286⟩
Article dans une revue hal-01996186v1
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The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation

Chih-Yuan Lee , Ting-Yu Lai , Meng-Kun Tsai , Yung-Chi Chang , Yu-Hsin Ho , et al.
Nature Communications, 2017, 8, pp.15502. ⟨10.1038/ncomms15502⟩
Article dans une revue hal-01996166v1
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Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression

Pieter Goossens , Juan Rodriguez-Vita , Anders Etzerodt , Marion Massé , Olivia Rastoin , et al.
Cell Metabolism, 2019, 29 (6), pp.1376-1389. ⟨10.1016/j.cmet.2019.02.016⟩
Article dans une revue hal-02359441v1

Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways

Daniel L. Villeneuve , Brigitte Landesmann , Paola Allavena , Noah Ashley , Anna Bal-Price , et al.
Toxicological Sciences, 2018, 163 (2), pp.346-352. ⟨10.1093/toxsci/kfy047⟩
Article dans une revue hal-02117997v1
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Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer

Anders Etzerodt , Morgane Moulin , Thomas Koed Doktor , Marcello Delfini , Noushine Mossadegh , et al.
Journal of Experimental Medicine, 2020, 217 (4), ⟨10.1084/jem.20191869⟩
Article dans une revue hal-02982706v1

The resolution of inflammation: anti-inflammatory roles for NF-kappaB.

Toby Lawrence , Carol Fong
International Journal of Biochemistry and Cell Biology, 2010, 42 (4), pp.519-23. ⟨10.1016/j.biocel.2009.12.016⟩
Article dans une revue istex hal-00553129v1

Specific targeting of CD163(+) TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression

Anders Etzerodt , Kyriaki Tsalkitzi , Maciej Maniecki , William Damsky , Marcello Delfini , et al.
Journal of Experimental Medicine, 2019, 216 (10), pp.2394-2411. ⟨10.1084/jem.20182124⟩
Article dans une revue hal-02359423v1

Macrophages and NF-κB in Cancer.

Toby Lawrence
Current Topics in Microbiology and Immunology, 2011, 349, pp.171-84. ⟨10.1007/82_2010_100⟩
Article dans une revue hal-00606019v1

Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection.

Arnaud Didierlaurent , John Goulding , Seema Patel , Robert Snelgrove , Lionel Low , et al.
Journal of Experimental Medicine, 2008, 205 (2), pp.323-9. ⟨10.1084/jem.20070891⟩
Article dans une revue inserm-00227540v1

Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression

James Opzoomer , Joanne Anstee , Isaac Dean , Emily Hill , Ihssane Bouybayoune , et al.
Science Advances , 2021, 7 (45), ⟨10.1126/sciadv.abg9518⟩
Article dans une revue hal-03566003v1

Targeting STAT3 and STAT5 in Tumor-Associated Immune Cells to Improve Immunotherapy

Gregory Verdeil , Toby Lawrence , Anne-Marie Schmitt-Verhulst , Nathalie Auphan-Anezin
Contemporary Southeast Asia, 2019, 11 (12), ⟨10.3390/cancers11121832⟩
Article dans une revue hal-02475040v1

The three members of the Vav family proteins form complexes that concur to foam cell formation and atherosclerosis[S]

Rong Huang , Guo Guo , Liaoxun Lu , Rui Fu , Jing Luo , et al.
Journal of Lipid Research, 2019, 60 (12), pp.2006-2019. ⟨10.1194/jlr.M094771⟩
Article dans une revue hal-02475041v1

The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans.

Kellie A Charles , Hagen Kulbe , Robin Soper , Monica Escorcio-Correia , Toby Lawrence , et al.
Journal of Clinical Investigation, 2009, 119 (10), pp.3011-23. ⟨10.1172/JCI39065⟩
Article dans une revue hal-00499385v1

Non-activatable mutant of inhibitor of kappa B kinase α (IKKα) exerts vascular site-specific effects on atherosclerosis in Apoe-deficient mice

Pathricia Tilstam , Josefin Soppert , Christian Hemmers , Eva Harlacher , Yvonne Döring , et al.
Atherosclerosis, 2020, 292, pp.23-30. ⟨10.1016/j.atherosclerosis.2019.10.023⟩
Article dans une revue hal-02998565v1

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-kappa B/STAT1-IRF1 Signaling

Emiel P. C. van Der Vorst , Kosta Theodorou , Yongzheng Wu , Marten A. Hoeksema , Pieter Goossens , et al.
Cell Metabolism, 2017, 25 (1), pp.197-207. ⟨10.1016/j.cmet.2016.10.013⟩
Article dans une revue hal-01996188v1

Nuclear factor-kappaB and tumor-associated macrophages.

Alessandra Mancino , Toby Lawrence
Clinical Cancer Research, 2010, 16 (3), pp.784-9. ⟨10.1158/1078-0432.CCR-09-1015⟩
Article dans une revue hal-00502962v1

NON-ACTIVATABLE MUTANT OF INHIBITOR OF KAPPA B KINASE alpha (IKK alpha) EXERTS SITE-SPECIFIC EFFECTS ON ATHEROSCLEROSIS

Pathricia V. Tilstam , Wendy Theelen , Setareh Alampour-Sarabi , Lukas Pawig , Yaw Asare , et al.
Nephrology Dialysis Transplantation, 2016, 31 (1), pp.48
Article dans une revue hal-01438539v1
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Molecular dissection of plasmacytoid dendritic cell activation in vivo during a viral infection

Elena Tomasello , Karima Naciri , Rabie Chelbi , Gilles Bessou , Anissa Fries , et al.
EMBO Journal, 2018, 37 (19), ⟨10.15252/embj.201798836⟩
Article dans une revue hal-02117981v1
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Tracking Dynamics of Spontaneous Tumors in Mice Using Photon-Counting Computed Tomography

Franca Cassol , Loriane Portal , Sylvie Richelme , Mathieu Dupont , Yannick Boursier , et al.
iScience, 2019, 21, pp.68-83. ⟨10.1016/j.isci.2019.10.015⟩
Article dans une revue hal-02368834v1
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Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone

Mohamed Habbeddine , Christophe Verthuy , Olivia Rastoin , Lionel Chasson , Magali Bebien , et al.
Cell Reports, 2017, 21 (9), pp.2515-2527. ⟨10.1016/j.celrep.2017.10.111⟩
Article dans une revue hal-02376107v1

The resolution of inflammation and cancer.

Juan Rodriguez-Vita , Toby Lawrence
Cytokine & Growth Factor Reviews, 2010, 21 (1), pp.61-5. ⟨10.1016/j.cytogfr.2009.11.006⟩
Article dans une revue istex hal-00553068v1