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Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis

Cecilia Patitucci , Juan Diego Hernández-Camacho , Elodie Vimont , Thomas Cokelaer , Thibault Chaze , et al.
2023
Pré-publication, Document de travail pasteur-04093359v1

TRIAP1/PRELI Complexes Prevent Apoptosis by Mediating Intramitochondrial Transport of Phosphatidic Acid

Christoph Potting , Takashi Tatsuta , Tim König , Mathias Haag , Timothy Wai , et al.
Cell Metabolism, 2013, 18 (2), pp.287-295. ⟨10.1016/j.cmet.2013.07.008⟩
Article dans une revue hal-02391085v1
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Mitochondrial Nucleic Acid as a Driver of Pathogenic Type I Interferon Induction in Mendelian Disease

Alice Lepelley , Timothy Wai , Yanick J Crow
Frontiers in Immunology, 2021, 12, pp.729763. ⟨10.3389/fimmu.2021.729763⟩
Article dans une revue pasteur-03382218v1

Loss of the mitochondrial i ‐ AAA protease YME 1L leads to ocular dysfunction and spinal axonopathy

Hans‐georg Sprenger , Gulzar Wani , Annika Hesseling , Tim König , Maria Patron , et al.
EMBO Molecular Medicine, 2018, 11 (1), ⟨10.15252/emmm.201809288⟩
Article dans une revue hal-02390990v1
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Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A

Alice Lepelley , Erika Della Mina , Erika van Nieuwenhove , Lise Waumans , Sylvie Fraitag , et al.
Journal of Experimental Medicine, 2021, 218 (10), pp.e20201560. ⟨10.1084/jem.20201560⟩
Article dans une revue hal-03736663v4

Mitochondrial Dynamics and Metabolic Regulation

Timothy Wai , Thomas Langer
Trends in Endocrinology and Metabolism = Trends in Endocrinology & Metabolism , 2016, 27 (2), pp.105-117. ⟨10.1016/j.tem.2015.12.001⟩
Article dans une revue hal-02391015v1
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Mitochondrial fission process 1 (MTFP1) controls bioenergetic efficiency and prevents inflammatory cardiomyopathy and heart failure in mice

Erminia Donnarumma , Michael Kohlhaas , Elodie Vimont , Etienne Kornobis , Thibault Chaze , et al.
2022
Pré-publication, Document de travail pasteur-03853920v1
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Mitochondrial Fission Process 1 controls inner membrane integrity and protects against heart failure

Erminia Donnarumma , Michael Kohlhaas , Elodie Vimont , Etienne Kornobis , Thibault Chaze , et al.
Nature Communications, 2022, 13 (1), pp.6634. ⟨10.1038/s41467-022-34316-3⟩
Article dans une revue pasteur-03853858v1

SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation

Marie Lagouge , Arnaud Mourier , Hyun Ju Lee , Henrik Spåhr , Timothy Wai , et al.
PLoS Genetics, 2015, 11 (8), pp.e1005423. ⟨10.1371/journal.pgen.1005423⟩
Article dans une revue hal-02391054v1

The i -AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

Ruchika Anand , Timothy Wai , Michael Baker , Nikolay Kladt , Astrid Schauss , et al.
Journal of Cell Biology, 2014, 204 (6), pp.919-929. ⟨10.1083/jcb.201308006⟩
Article dans une revue hal-02391074v1
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High‐throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts

Emma Cretin , Priscilla Lopes , Elodie Vimont , Takashi Tatsuta , Thomas Langer , et al.
EMBO Molecular Medicine, 2021, pp.e13579. ⟨10.15252/emmm.202013579⟩
Article dans une revue pasteur-03242195v1

Cloning a novel mitochondrial protein which regulates tissue-specific mtDNA segregation

Riikka Jokinen⁎ , Paula Marttinen , Katarin Sandell , Tuula Manninen , Heli Teerenhovi , et al.
Mitochondrion, 2011, 11 (4), pp.641-642. ⟨10.1016/j.mito.2011.03.023⟩
Article dans une revue hal-02391258v1

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission

Christoph Freyer , Lynsey Cree , Arnaud Mourier , James Stewart , Camilla Koolmeister , et al.
Nature Genetics, 2012, 44 (11), pp.1282-1285. ⟨10.1038/ng.2427⟩
Article dans une revue hal-02391255v1

Stomatin-Like Protein 2 Is Required for In Vivo Mitochondrial Respiratory Chain Supercomplex Formation and Optimal Cell Function

Panagiotis Mitsopoulos , Yu-Han Chang , Timothy Wai , Tim König , Stanley Dunn , et al.
Molecular and Cellular Biology, 2015, 35 (10), pp.1838-1847. ⟨10.1128/MCB.00047-15⟩
Article dans une revue hal-02391067v1
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Quality control of the mitochondrion

Matthew Yoke Wui Ng , Timothy Wai , Anne Simonsen
Developmental Cell, 2021, 56 (7), pp.881 - 905. ⟨10.1016/j.devcel.2021.02.009⟩
Article dans une revue pasteur-03272624v1

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice

Timothy Wai , J. Garcia-Prieto , Mark D. Baker , C. Merkwirth , P. Benit , et al.
Science, 2015, 350 (6265), pp.aad0116-aad0116. ⟨10.1126/science.aad0116⟩
Article dans une revue hal-02403885v1
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Mitochondrial dysfunction caused by novel ATAD3A mutations

Nathalie Dorison , Pauline Gaignard , Aurélien Bayot , Antoinette Gelot , Pierre Hadrien Becker , et al.
Molecular Genetics and Metabolism, 2020, ⟨10.1016/j.ymgme.2020.09.002⟩
Article dans une revue hal-02964011v1
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Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling

Anna Spier , Michael Connor , Thomas Steiner , Filipe Carvalho , Pascale Cossart , et al.
Cell Reports, 2021, 37 (6), pp.109989. ⟨10.1016/j.celrep.2021.109989⟩
Article dans une revue hal-03520503v1
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Distinct molecular signatures of fission predict mitochondrial degradation or proliferation

Tatjana Kleele , Timo Rey , Julius Winter , Sofia Zaganelli , Dora Mahecic , et al.
2021
Pré-publication, Document de travail pasteur-03101257v1

Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research

Mathias Hohl , Hossein Ardehali , Francisco Azuaje , Ross Breckenridge , Wolfram Doehner , et al.
European Journal of Heart Failure, 2014, 16 (1), pp.6-14. ⟨10.1002/ejhf.10⟩
Article dans une revue hal-02391079v1
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Distinct fission signatures predict mitochondrial degradation or biogenesis

Tatjana Kleele , Timo Rey , Julius Winter , Sofia Zaganelli , Dora Mahecic , et al.
Nature, 2021, 593 (7859), pp.435-439. ⟨10.1038/s41586-021-03510-6⟩
Article dans une revue pasteur-03382143v1

Metabolic regulation of heart failure caused by imbalanced mitochondrial dynamics

Livier Estefani de La Rosa Vargas , E. Dale Abel , T. Langer , Timothy Wai
Archives of Cardiovascular Diseases Supplements, May 2019, Riga, Latvia. pp.242-243, ⟨10.1016/j.acvdsp.2019.02.133⟩
Communication dans un congrès hal-02390984v1

CHCHD10 and SLP2 control the stability of the PHB complex: a key factor for motor neuron viability

Emmanuelle C Genin , Sylvie Bannwarth , Baptiste Ropert , Françoise Lespinasse , Alessandra Mauri-Crouzet , et al.
Brain - A Journal of Neurology , 2022, 145 (10), pp.3415-3430. ⟨10.1093/brain/awac197⟩
Article dans une revue pasteur-03853884v1
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MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy

Claire Pujol , Elise Lebigot , Pauline Gaignard , Said Galai , Ichraf Kraoua , et al.
Brain - A Journal of Neurology , 2022, pp.awac444. ⟨10.1093/brain/awac444⟩
Article dans une revue pasteur-03934309v1
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The role of mitochondrial DNA copy number in mammalian fertility.

Timothy Wai , Asangla Ao , Xiaoyun Zhang , Daniel Cyr , Daniel Dufort , et al.
Biology of Reproduction, 2010, 83 (1), pp.52-62. ⟨10.1095/biolreprod.109.080887⟩
Article dans une revue pasteur-00819522v1
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Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation

Bianca Hartmann , Timothy Wai , Hao Hu , Thomas Macvicar , Luciana Musante , et al.
Article dans une revue hal-02391012v1

The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis

Christopher j. Hlynialuk , Binbing Ling , Zakery n. Baker , Paul a. Cobine , Lisa d. Yu , et al.
Cell Reports, 2015, 10 (6), pp.933-943. ⟨10.1016/j.celrep.2015.01.019⟩
Article dans une revue hal-02391071v1

Gimap3 Regulates Tissue-Specific Mitochondrial DNA Segregation

Riikka Jokinen , Paula Marttinen , Helen Katarin Sandell , Tuula Manninen , Heli Teerenhovi , et al.
PLoS Genetics, 2010, 6 (10), pp.e1001161. ⟨10.1371/journal.pgen.1001161⟩
Article dans une revue hal-02391264v1

MTFP1 loss sensitizes to mtDNA-driven sterile inflammation and heart failure in mice

Erminia Donnarumma , Elodie Vimont , Timothy Wai
Archives of Cardiovascular Diseases Supplements, 2023, 15 (2), pp.210. ⟨10.1016/j.acvdsp.2023.03.070⟩
Article dans une revue pasteur-04257984v1
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Mitochondrial dynamics and metabolic regulation control T cell fate in the thymus

Rima Elhage , Mairead Kelly , Nicolas Goudin , Jérôme Megret , Agnès Legrand , et al.
Frontiers in Immunology, 2024, 14, pp.1270268. ⟨10.3389/fimmu.2023.1270268⟩
Article dans une revue pasteur-04529642v1