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thomas freret

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Genetic Background Influence on Hippocampal Synaptic Plasticity: Frequency-Dependent Variations between an Inbred and an Outbred Mice Strain

Candice Roux , Pierre Lecouflet , Jean-Marie Billard , Elise Esneault , Marianne Leger
International Journal of Molecular Sciences, 2023, 24 (5), pp.4304. ⟨10.3390/ijms24054304⟩
Article dans une revue hal-04212361v1
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5-HT6 Receptors Sex-Dependently Modulate Hippocampal Synaptic Activity through GABA Inhibition

Caroline Lahogue , Jean-Marie Billard , Thomas Freret , Valentine Bouet
Biomolecules, 2023, 13 (5), pp.751. ⟨10.3390/biom13050751⟩
Article dans une revue hal-04089829v1

Association between road traffic accidents and drugs belonging to the antiseizure medications class: A pharmacovigilance analysis in VigiBase

Basile Chrétien , Sophie Nguyen , Charles Dolladille , Pierre‐marie Morice , Marie Heraudeau
British Journal of Clinical Pharmacology, 2022, ⟨10.1111/bcp.15481⟩
Article dans une revue hal-03832961v1
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Improved NMDA Receptor Activation by the Secreted Amyloid-Protein Precursor-α in Healthy Aging: A Role for D-Serine?

Jean-Marie Billard , Thomas Freret
International Journal of Molecular Sciences, 2022, 23, ⟨10.3390/ijms232415542⟩
Article dans une revue hal-03910923v1

Functional Dysregulations in CA1 Hippocampal Networks of a 3-Hit Mouse Model of Schizophrenia

Solenn Percelay , Jean-Marie Billard , Thomas Freret , Annie Andrieux , Michel Boulouard
International Journal of Molecular Sciences, 2021, 22 (5), pp.2644. ⟨10.3390/ijms22052644⟩
Article dans une revue hal-03238069v1

A new 3-hit mouse model of schizophrenia built on genetic, early and late factors

Valentine Bouet , Solenn Percelay , Elise Leroux , Boubacar Diarra , Marianne Léger
Schizophrenia Research, 2021, 228, pp.519-528. ⟨10.1016/j.schres.2020.11.043⟩
Article dans une revue hal-04212366v1
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Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer’s disease

François-Xavier Toublet , Julien Lalut , Bérénice Hatat , Cédric Lecoutey , Audrey Davis
European Journal of Medicinal Chemistry, 2021, 210, pp.113059. ⟨10.1016/j.ejmech.2020.113059⟩
Article dans une revue hal-03082877v1

Fast Anxiolytic-Like Effect Observed in the Rat Conditioned Defensive Burying Test, after a Single Oral Dose of Natural Protein Extract Products

Thomas Freret , Stacy Largilliere , Gerald Nee , Melanie Coolzaet , Sophie Corvaisier
Nutrients, 2021, 13 (7), pp.2445. ⟨10.3390/nu13072445⟩
Article dans une revue hal-03471908v1

Memory Disorders Related to Hippocampal Function: The Interest of 5-HT4Rs Targeting

Candice Roux , Marianne Leger , Thomas Freret
International Journal of Molecular Sciences, 2021, 22 (21), pp.12082. ⟨10.3390/ijms222112082⟩
Article dans une revue hal-03471906v1

Combination of MAP6 deficit, maternal separation and MK801 in female mice: A 3-hit animal model of neurodevelopmental disorder with cognitive deficits

Solenn Percelay , Thomas Freret , Nicole Turnbull , Valentine Bouet , Michel Boulouard
Behavioural Brain Research, 2021, 413, ⟨10.1016/j.bbr.2021.113473⟩
Article dans une revue hal-04316243v1
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Interplay between 5-HT4 receptors and GABAergic system within CA1 hippocampal synaptic plasticity

Pierre Lecouflet , Candice Roux , B Potier , Marianne Leger , Elie Brunet
Cerebral Cortex, 2021, 31 (1), pp.694-701. ⟨10.1093/cercor/bhaa253⟩
Article dans une revue hal-03371418v1
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Dopaminergic neuromodulation of prefrontal cortex activity requires the NMDA receptor co-agonist D-serine

Glenn Dallérac , Xia Li , Pierre Lecouflet , Nadège Morisot , Silvia Sacchi
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (23), pp.e2023750118. ⟨10.1073/pnas.2023750118⟩
Article dans une revue hal-03331836v1

Interplay between 5-HT4 Receptors and GABAergic System within CA1 Hippocampal Synaptic Plasticity

Pierre Lecouflet , Candice M. Roux , Brigitte Potier , Marianne Leger , Elie Brunet
Cerebral Cortex, 2020, 31 (1), pp.694-701. ⟨10.1093/cercor/bhaa253⟩
Article dans une revue hal-03040826v1

Antipsychotic lurasidone: Behavioural and pharmacokinetic data in C57BL/6 mice

Solenn Percelay , Marc Since , S. Lagadu , Thomas Freret , Valentine Bouet
Pharmacology Biochemistry and Behavior, 2020, 194, pp.172933. ⟨10.1016/j.pbb.2020.172933⟩
Article dans une revue hal-03602034v1
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D-serine in physiological and pathological brain aging

E. Ploux , T Freret , Jean-Marie Billard
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020, pp.140542. ⟨10.1016/j.bbapap.2020.140542⟩
Article dans une revue hal-02947335v1
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Serine Racemase Deletion Affects the Excitatory/Inhibitory Balance of the Hippocampal CA1 Network

Eva Ploux , Valentine Bouet , Inna Radzishevsky , Herman Wolosker , Thomas Freret
International Journal of Molecular Sciences, 2020, 21 (24), pp.9447. ⟨10.3390/ijms21249447⟩
Article dans une revue hal-03072318v1
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Donecopride, a Swiss army knife with potential interest against Alzheimer's disease

Christophe Rochais , Cédric Lecoutey , Katia Hamidouche , Patrizia Giannoni , Florence Gaven
British Journal of Pharmacology, inPress, 177 (9), pp.1988-2005. ⟨10.1111/bph.14964⟩
Article dans une revue hal-02428730v1
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Author Correction: Dual orexin receptor antagonist induces changes in core body temperature in rats after exercise

Tristan Martin , Yves Dauvilliers , Ouma-Chandrou Koumar , Valentine Bouet , Thomas Freret
Scientific Reports, 2020, 10 (1), pp.6030. ⟨10.1038/s41598-020-62685-6⟩
Article dans une revue hal-03518966v1

Long-Term Music Exposure Prevents Age-Related Cognitive Deficits in Rats Independently of Hippocampal Neurogenesis

Lou Rizzolo , Marianne Leger , Sophie Corvaisier , Mathilde Groussard , Hervé Platel
Cerebral Cortex, 2020, 31 (1), pp.620-634. ⟨10.1093/cercor/bhaa247⟩
Article dans une revue hal-03019700v1
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Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer’s Disease

François-Xavier Toublet , Cédric Lecoutey , Julien Lalut , Bérénice Hatat , Audrey Davis
Molecules, 2019, 24 (15), pp.2786. ⟨10.3390/molecules24152786⟩
Article dans une revue hal-02399906v1
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A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT4R) Agonist and Serotonergic Subtype 6 Receptor (5-HT6R) Inverse Agonist Activities, With a Potential Interest Against Alzheimer’s Disease

Bérénice Hatat , Samir Yahiaoui , Cédric Lecoutey , Audrey Davis , Thomas Freret
Frontiers in Aging Neuroscience, 2019, 11, pp.148. ⟨10.3389/fnagi.2019.00148⟩
Article dans une revue hal-02399864v1
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Dual orexin receptor antagonist induces changes in core body temperature in rats after exercise

Tristan Martin , Yves Dauvilliers , Ouma-Chandrou Koumar , Valérie Bouet , Thomas Freret
Scientific Reports, 2019, 9 (1), pp.18432. ⟨10.1038/s41598-019-54826-3⟩
Article dans une revue hal-02400711v1

Asc-1 transporter activation: an alternative to rescue age-related alterations in functional plasticity at rat hippocampal CA3/CA1 synapses

Jean-Marie Billard , Thomas Freret
Journal of Neurochemistry, 2018, 147 (4), pp.514-525. ⟨10.1111/jnc.14586⟩
Article dans une revue hal-02135230v1
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Evaluation of the impact of S-adenosylmethionine-dependent methyltransferase inhibitor, 3-deazaneplanocin A, on tissue injury and cognitive function in mice

Eva Lhuissier , Juliette Aury-Landas , Valentine Bouët , Céline Bazille , Yohann Repesse
Oncotarget, 2018, 9 (29), pp.20698 - 20708. ⟨10.18632/oncotarget.25062⟩
Article dans une revue hal-01796395v1

Characterizing age-related decline of recognition memory and brain activation profile in mice

Hassina Belblidia , Marianne Leger , Abdelmalek Abdelouadoud , Anne Quiedeville , Floriane Calocer
Experimental Gerontology, 2018, 106, pp.222-231. ⟨10.1016/j.exger.2018.03.006⟩
Article dans une revue hal-01733066v1

Repeated dexamphetamine treatment alters the dopaminergic system and increases the phMRI response to methylphenidate

Anouk Schrantee , Jordi Tremoleda , Marzena Wylezinska-Arridge , Valentine Bouet , Peter Hesseling
PLoS ONE, 2017, 12 (2), pp.e0172776. ⟨10.1371/journal.pone.0172776⟩
Article dans une revue hal-02135218v1

LP-211, a selective 5-HT 7 receptor agonist, increases novelty-preference and promotes risk-prone behavior in rats

G. Beaudet , E. Paizanis , F. Zoratto , E. Lacivita , M. Leopoldo
Synapse, 2017, 71 (12), pp.e21995. ⟨10.1002/syn.21995⟩
Article dans une revue hal-02193575v1

Deletion of the serotonin receptor type 7 disrupts the acquisition of allocentric but not egocentric navigation strategies in mice

Gregory Beaudet , Christelle Jozet-Alves , Rachel Asselot , Pascale Schumann-Bard , Thomas Freret
Behavioural Brain Research, 2017, 320 (1), pp.179 - 185. ⟨10.1016/j.bbr.2016.12.006⟩
Article dans une revue hal-01472663v1

Co-modulation of an allosteric modulator of nicotinic receptor-cholinesterase inhibitor (galantamine) and a 5-HT4 receptor agonist (RS-67333): effect on scopolamine-induced memory deficit in the mouse

Thomas Freret , Véronique Lelong-Boulouard , Pierre Lecouflet , Katia Hamidouche , François Dauphin
Psychopharmacology, 2017, 234 (15), pp.2365-2374. ⟨10.1007/s00213-017-4664-z⟩
Article dans une revue hal-02135214v1

Long-Lasting Effects of Chronic Intermittent Alcohol Exposure in Adolescent Mice on Object Recognition and Hippocampal Neuronal Activity.

G Beaudet , S Valable , J Bourgine , V Lelong-Boulouard , L Lanfumey
Alcoholism: Clinical and Experimental Research, 2016, 40 (12), pp.2591-2603. ⟨10.1111/acer.13256⟩
Article dans une revue hal-01576066v1

Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT 4 R) partial agonist and 5-HT 6 R antagonist activities, as potential treatment of Alzheimer’s disease

Samir Yahiaoui , Katia Hamidouche , Céline Ballandonne , Audrey Davis , Jana Sopkova-de Oliveira Santos
European Journal of Medicinal Chemistry, 2016, 121, pp.283-293. ⟨10.1016/j.ejmech.2016.05.048⟩
Article dans une revue hal-02043759v1
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Usefulness of Time-Point Serum Cortisol and ACTH Measurements for the Adjustment of Glucocorticoid Replacement in Adrenal Insufficiency

Elise Rousseau , Michael Joubert , Géraldine Trzepla , Jean Jacques Parienti , Thomas Freret
PLoS ONE, 2015, 10 (8), pp.e0135975. ⟨10.1371/journal.pone.0135975⟩
Article dans une revue hal-02190958v1

Effects of acute administration of melatonin on attentional, executive, and working memory processes in rats

Christophe Liet , Fella Amenouche , Thomas Freret , Michel Boulouard , Benoit Mauvieux
Fundamental & Clinical Pharmacology, 2015, 29 (5), pp.472-477. ⟨10.1111/fcp.12134⟩
Article dans une revue hal-02193380v1

Time decay of object, place and temporal order memory in a paradigm assessing simultaneously episodic-like memory components in mice

Hassina Belblidia , Abdelmalek Abdelouadoud , Christelle Jozet-Alves , Hélène Dumas , Thomas Freret
Behavioural Brain Research, 2015, 286, pp.80--84. ⟨10.1016/j.bbr.2015.02.043⟩
Article dans une revue hal-01472655v1

Therapeutic Potential of 5-HT 6 Receptor Agonists

Delphine Karila , Thomas Freret , Valentine Bouet , Michel Boulouard , Patrick Dallemagne
Journal of Medicinal Chemistry, 2015, 58 (20), pp.7901-7912. ⟨10.1021/acs.jmedchem.5b00179⟩
Article dans une revue hal-02043781v1

Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances

Anne Quiedeville , Michel Boulouard , Katia Hamidouche , Virginie da Silva Costa-Aze , Gerald Nee
Behavioural Brain Research, 2015, 293, pp.10-17. ⟨10.1016/j.bbr.2015.07.020⟩
Article dans une revue hal-02043824v1

Effects of long-term methylphenidate treatment in adolescent and adult rats on hippocampal shape, functional connectivity and adult neurogenesis

K. van Der Marel , V. Bouet , G.F. Meerhoff , T. Freret , M. Boulouard
Neuroscience, 2015, 309, pp.243-258. ⟨10.1016/j.neuroscience.2015.04.044⟩
Article dans une revue hal-02193376v1
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Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT 4 R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride

Cédric Lecoutey , Cédric Lecoutey , Florence Gaven , Patrizia Giannoni , Katia Hamidouche
Journal of Medicinal Chemistry, 2015, 58 (7), pp.3172-3187. ⟨10.1021/acs.jmedchem.5b00115⟩
Article dans une revue hal-02043873v1
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Spatial memory deficit across aging: current insights of the role of 5-HT7 receptors

Gregory Beaudet , Valentine Bouet , Christelle Jozet-Alves , Pascale Schumann-Bard , Francois Dauphin
Frontiers in Behavioral Neuroscience, 2015, 8, pp.448. ⟨10.3389/fnbeh.2014.00448⟩
Article dans une revue hal-01472654v1

Environmental Enrichment Duration Differentially Affects Behavior and Neuroplasticity in Adult Mice

Marianne Leger , Eleni Paizanis , Kwamivi Dzahini , Anne Quiedeville , Valentine Bouet
Cerebral Cortex, 2015, 25 (11), pp.4048-4061. ⟨10.1093/cercor/bhu119⟩
Article dans une revue hal-02135292v1

Mechanisms underlying the neuroprotective effect of brain reserve against late life depression

Thomas Freret , Pierrette Gaudreau , Pascale Schumann-Bard , Jean-Marie Billard , Aurel Popa-Wagner
Journal of Neural Transmission, 2015, 122 (S1), pp.55-61. ⟨10.1007/s00702-013-1154-2⟩
Article dans une revue hal-02325092v1

Dual Histamine H3R/Serotonin 5-HT4R Ligands with Antiamnesic Properties: Pharmacophore-Based Virtual Screening and Polypharmacology.

Alban Lepailleur , Thomas Freret , Stéphane Lemaître , Michel Boulouard , François Dauphin
Journal of Chemical Information and Modeling, 2014, 54 (6), pp.1773-1784
Article dans une revue hal-01064770v1
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Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment

Cédric Lecoutey , Damien Hedou , Thomas Freret , Patrizia Giannoni , Florence Gaven
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (36), pp.E3825--30. ⟨10.1073/pnas.1410315111⟩
Article dans une revue hal-01800439v2

Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease

Javier Becerril-Ortega , Karim Bordji , Thomas Freret , Travis Rush , Alain Buisson
Neurobiology of Aging, 2014, 35 (10), pp.2288 - 2301. ⟨10.1016/j.neurobiolaging.2014.04.019⟩
Article dans une revue hal-01626647v1

Object recognition test in mice

Marianne Leger , Anne Quiedeville , Valentine Bouet , Benoît Haelewyn , Michel Boulouard
Nature Protocols, 2013, 8 (12), pp.2531-2537. ⟨10.1038/nprot.2013.155⟩
Article dans une revue hal-02135259v1

Genomic transcriptional profiling in LOU/C/Jall rats identifies genes for successful aging

Véronique Paban , Jean-Marie Billard , Valentine Bouet , Thomas Freret , Michel Boulouard
Brain Structure and Function, 2013, 218 (6), pp.1501-1512. ⟨10.1007/s00429-012-0472-8⟩
Article dans une revue hal-02325134v1

New orally effective 3-(2-nitro)phenylpropanamide analgesic derivatives: Synthesis and antinociceptive evaluation

Marc Since , Thomas Freret , Gerald Nee , Thierry Terme , Patrice Vanelle
European Journal of Medicinal Chemistry, 2013, 69, pp.728--734. ⟨10.1016/j.ejmech.2013.08.041⟩
Article dans une revue hal-01460473v1

A biphasic and brain-region selective down-regulation of cyclic adenosine monophosphate concentrations supports object recognition in the rat.

Maïte Hotte , François Dauphin , Thomas Freret , Michel Boulouard , Guenaëlle Levallet
PLoS ONE, 2012, 7 (2), pp.e32244. ⟨10.1371/journal.pone.0032244⟩
Article dans une revue hal-00862771v1

Spatial and non-spatial performance in mutant mice devoid of otoliths.

M. L. Machado , N. Kroichvili , T. Freret , B. Philoxène , V. Lelong-Boulouard
Neuroscience Letters, 2012, 522 (1), pp.57-61. ⟨10.1016/j.neulet.2012.06.016⟩
Article dans une revue hal-00866394v1

Genomic transcriptional profiling in LOU/C/Jall rats identifies genes for successful aging.

Véronique Paban , Jean-Marie Billard , Valentine Bouet , Thomas Freret , Michel Boulouard
Brain Structure and Function, 2012, 218 (6), pp.1501-1512. ⟨10.1007/s00429-012-0472-8⟩
Article dans une revue hal-00862299v1

Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice.

Thomas Freret , Valentine Bouet , Anne Quiedeville , Gérald Nee , Patrick Dallemagne
Behavioural Brain Research, 2012, 230 (1), pp.304-8. ⟨10.1016/j.bbr.2012.02.012⟩
Article dans une revue hal-00862757v1

Influence of anxiety in spatial memory impairments related to the loss of vestibular function in rat.

M. L. Machado , V. Lelong-Boulouard , P. F. Smith , T. Freret , B. Philoxene
Neuroscience, 2012, 218, pp.161-9. ⟨10.1016/j.neuroscience.2012.05.029⟩
Article dans une revue hal-00866396v1
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Vezatin is essential for dendritic spine morphogenesis and functional synaptic maturation.

Lydia Danglot , Thomas Freret , Nicolas Le Roux , Nicolas Narboux Nême , Andrea Burgo
Journal of Neuroscience, 2012, 32 (26), pp.9007-22. ⟨10.1523/JNEUROSCI.3084-11.2012⟩
Article dans une revue hal-00776396v1

Rescue of cognitive aging by long-lasting environmental enrichment exposure initiated before median lifespan.

T. Freret , J.-M. Billard , P. Schumann-Bard , P. Dutar , F. Dauphin
Neurobiol Aging, 2012, 33 (5), pp.1005.e1-10. ⟨10.1016/j.neurobiolaging.2011.09.028⟩
Article dans une revue hal-00866400v1

Rescue of cognitive aging by long-lasting environmental enrichment exposure initiated before median lifespan

T. Freret , Jean-Marie Billard , P. Schumann-Bard , P. Dutar , F. Dauphin
Neurobiology of Aging, 2012, 33 (5), pp.1005.e1-1005.e10. ⟨10.1016/j.neurobiolaging.2011.09.028⟩
Article dans une revue hal-02325180v1

Influence of vestibular input on spatial and nonspatial memory and on hippocampal NMDA receptors.

S. Besnard , M. L. Machado , G. Vignaux , M. Boulouard , A. Coquerel
Hippocampus, 2012, 22 (4), pp.814-26. ⟨10.1002/hipo.20942⟩
Article dans une revue hal-00866441v1
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Environmental enrichment enhances episodic-like memory in association with a modified neuronal activation profile in adult mice.

Marianne Leger , Anne Quiedeville , Eleni Paizanis , Sharuja Natkunarajah , Thomas Freret
PLoS ONE, 2012, 7 (10), pp.e48043. ⟨10.1371/journal.pone.0048043⟩
Article dans une revue hal-00862786v1

Post-stroke depression: mechanisms, translation and therapy.

Isabelle Loubinoux , Golo Kronenberg , Matthias Endres , Pascale Schumann-Bard , Thomas Freret
Journal of Cellular and Molecular Medicine, 2012, 16 (9), pp.1961-9. ⟨10.1111/j.1582-4934.2012.01555.x⟩
Article dans une revue hal-00862834v1

Repeated mild hypoxic exposures decrease anxiety-like behavior in the adult mouse together with an increased brain adrenomedullin gene expression.

Claire Leconte , Marianne Léger , Michel Boulouard , Emmanuelle Tixier , Thomas Fréret
Behavioural Brain Research, 2012, 230 (1), pp.78-84. ⟨10.1016/j.bbr.2012.01.054⟩
Article dans une revue hal-00862777v1

Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT4 receptor activation (RS67333) on object recognition in mice.

Thomas Freret , Valentine Bouet , Anne Quiedeville , Gerald Nee , Patrick Dallemagne
Behavioural Brain Research, 2012, 230, pp.304-308
Article dans une revue hal-00821461v1

Age-dependent effects of chronic fluoxetine treatment on the serotonergic system one week following treatment.

Valentine Bouet , Anne Klomp , Thomas Freret , Marzena Wylezinska-Arridge , Jordi Lopez-Tremoleda
Psychopharmacology, 2012, 221 (2), pp.329-39. ⟨10.1007/s00213-011-2580-1⟩
Article dans une revue hal-00862306v1

Maternal hypertension during pregnancy modifies the response of the immature brain to hypoxia-ischemia: sequential MRI and behavioral investigations.

Annelise Letourneur , Thomas Freret , Simon Roussel , Michel Boulouard , Didier Divoux
Experimental Neurology, 2012, 233 (1), pp.264-72. ⟨10.1016/j.expneurol.2011.10.014⟩
Article dans une revue hal-00862822v1

Environmental enrichment improves recent but not remote memory in association with a modified brain metabolic activation profile in adult mice.

Marianne Leger , Valentine Bouet , Thomas Freret , Anne-Sophie Darmaillacq , Matthieu Dacher
Behavioural Brain Research, 2012, 228 (1), pp.22-9. ⟨10.1016/j.bbr.2011.11.022⟩
Article dans une revue hal-00862779v1

On the importance of long-term functional assessment after stroke to improve translation from bench to bedside.

Thomas Freret , Pascale Schumann-Bard , Michel Boulouard , Valentine Bouet
Experimental and Translational Stroke Medicine, 2011, 3, pp.6. ⟨10.1186/2040-7378-3-6⟩
Article dans une revue hal-00862997v1

Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals.

Valentine Bouet , Thomas Freret , Patrick Dutar , Jean-Marie Billard , Michel Boulouard
Mechanisms of Ageing and Development, 2011, 132 (5), pp.240-8. ⟨10.1016/j.mad.2011.04.006⟩
Article dans une revue hal-00862993v1

Effect of pre- versus post-weaning environmental disturbances on social behaviour in mice.

Valentine Bouet , Blandine Lecrux , Gwenaelle Tran , Thomas Freret
Neuroscience Letters, 2011, 488 (2), pp.221-4. ⟨10.1016/j.neulet.2010.11.033⟩
Article dans une revue hal-00862841v1

Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals

Valentine Bouet , Thomas Freret , Patrick Dutar , Jean-Marie Billard , Michel Boulouard
Mechanisms of Ageing and Development, 2011, 132 (5), pp.240-248. ⟨10.1016/j.mad.2011.04.006⟩
Article dans une revue hal-02325196v1

Predicting sensorimotor and memory deficits after neonatal ischemic stroke with reperfusion in the rat.

Valentine Bouet , Thomas Freret , Steve Ankri , Madeleine Bezault , Sylvain Renolleau
Behavioural Brain Research, 2010, 212 (1), pp.56-63. ⟨10.1016/j.bbr.2010.03.043⟩
Article dans une revue hal-00863083v1
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Improvements of the Stroke Model Guidelines -Animal body weight and long-term functional concerns

Thomas Freret , Valentine Bouet
Journal of Experimental Stroke & Translational Medicine, 2009
Article dans une revue hal-04358233v1

Behavioral deficits after distal focal cerebral ischemia in mice: Usefulness of adhesive removal test.

Thomas Freret , Valentine Bouet , Claire Leconte , Simon Roussel , Laurent Chazalviel
Behavioral Neuroscience, 2009, 123 (1), pp.224-30. ⟨10.1037/a0014157⟩
Article dans une revue hal-00863264v1

The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice.

Valentine Bouet , Michel Boulouard , Jérôme Toutain , Didier Divoux , Myriam Bernaudin
Nature Protocols, 2009, 4 (10), pp.1560-4. ⟨10.1038/nprot.2009.125⟩
Article dans une revue hal-00863258v1

Tetrahydroisoquinolines as dopaminergic ligands: 1-Butyl-7-chloro-6-hydroxy-tetrahydroisoquinoline, a new compound with antidepressant-like activity in mice.

Inmaculada Berenguer , Noureddine El Aouad , Sebastián Andujar , Vanessa Romero , Fernando Suvire
Bioorganic and Medicinal Chemistry, 2009, 17 (14), pp.4968-80. ⟨10.1016/j.bmc.2009.05.079⟩
Article dans une revue hal-00863255v1

Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse.

Claire Leconte , Emmanuelle Tixier , Thomas Freret , Jérôme Toutain , Romaric Saulnier
Stroke, 2009, 40 (10), pp.3349-55. ⟨10.1161/STROKEAHA.109.557314⟩
Article dans une revue hal-00863295v1

Combined therapeutic strategy using erythropoietin and mesenchymal stem cells potentiates neurogenesis after transient focal cerebral ischemia in rats.

Elise Esneault , Emilie Pacary , Dauphou Eddi , Thomas Freret , Emmanuelle Tixier
Journal of Cerebral Blood Flow and Metabolism, 2008, 28 (9), pp.1552-63. ⟨10.1038/jcbfm.2008.40⟩
Article dans une revue hal-00863330v1

Intraluminal thread model of focal stroke in the non-human primate

Thomas Freret , Valentine Bouet , Jérôme Toutain , Romaric Saulnier , Palma Pro-Sistiaga
Journal of Cerebral Blood Flow and Metabolism, 2008, 28 (4), pp.786-96. ⟨10.1038/sj.jcbfm.9600575⟩
Article dans une revue hal-00863332v1

Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse.

Valentine Bouët , Thomas Freret , Jérôme Toutain , Didier Divoux , Michel Boulouard
Experimental Neurology, 2007, 203 (2), pp.555-67. ⟨10.1016/j.expneurol.2006.09.006⟩
Article dans une revue hal-00178296v1

Long-term evaluation of sensorimotor and mnesic behaviour following striatal NMDA-induced unilateral excitotoxic lesion in the mouse.

Benoît Haelewyn , Thomas Freret , Emilie Pacary , Pascale Schumann-Bard , Michel Boulouard
Behavioural Brain Research, 2007, 178 (2), pp.235-43. ⟨10.1016/j.bbr.2006.12.023⟩
Article dans une revue hal-00178443v1

Long-term evaluation of sensorimotor and mnesic behaviour following striatal NMDA-induced unilateral excitotoxic lesion in the mouse

Benoît Haelewyn , Thomas Freret , Emilie Pacary , Pascale Schumann-Bard , Michel Boulouard
Behavioural Brain Research, 2007, 178, pp.235-243. ⟨10.1016/j.bbr.2006.12.023⟩
Article dans une revue hal-00867870v1

Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat.

T. Freret , S. Valable , L. Chazalviel , R. Saulnier , E.T. Mackenzie
European Journal of Neuroscience, 2006, 23, pp.1757-1765
Article dans une revue hal-00023477v1

Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat.

Thomas Freret , Samuel Valable , Laurent Chazalviel , Romaric Saulnier , Eric T Mackenzie
European Journal of Neuroscience, 2006, 23 (7), pp.1757-65. ⟨10.1111/j.1460-9568.2006.04699.x⟩
Article dans une revue hal-00865370v1

Effect of hypoxic preconditioning on brain genomic response before and following ischemia in the adult mouse: identification of potential neuroprotective candidates for stroke

Y. Tang , E. Pacary , T. Freret , D. Divoux , E. Petit
Neurobiology of Disease, 2006, 21, pp.18-28
Article dans une revue hal-00018635v1

Long-term functional outcome following transient middle cerebral artery occlusion in the rat: correlation between brain damage and behavioral impairment.

Thomas Freret , Laurent Chazalviel , Simon Roussel , Myriam Bernaudin , Pascale Schumann-Bard
Behavioral Neuroscience, 2006, 120 (6), pp.1285-98. ⟨10.1037/0735-7044.120.6.1285⟩
Article dans une revue hal-00865366v1

Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse

Valentine Bouet , Thomas Freret , J. Toutain , Didier Divoux , Michel Boulouard
Experimental Neurology, 2006, 203, pp.55-567. ⟨10.1016/j.expneurol.2006.09.006⟩
Article dans une revue hal-00867774v1
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Contrôle et correction des variables physiologiques en IRM fonctionnelle cérébrale chez l'homme et le rat anesthésié

Marin Mauboussin , Coline Vanschamelhout , Nicolas Delcroix , Marc Joliot , Thomas Freret
6ème Congrès de la Société française de résonance magnétique en biologie et médecine, Mar 2023, Paris, France.
Poster de conférence hal-04065412v1
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Can physiological signals estimation improve fMRI connectivity assessment in anesthetized rats?

Mikael Naveau , Coline Vanschamelhout , Marin Mauboussin , Romaric Saulnier , Palma Pro-Sistiaga
OHBM2022, Jun 2022, Glasgow, United Kingdom.
Poster de conférence hal-03878758v1
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Altering glutamate transmission in combination with an early post-natal stress to mimic schizophrenia in male and female mice

F Menager , Solenn Percelay , T. Freret , M. Boulouard , Jean-Marie Billard
Journée Normande de Recherche Biomédicale, Nov 2019, Caen, France
Poster de conférence hal-02363095v1
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Impact of d-serine depletion in the β-amyloid cascade related to Alzheimer’s disease

T. Freret , E Ploux , L. Gorisse , I Radzishevsky , H Wolosker
Annual Meeting of the Society for Neuroscience (SFN), Oct 2019, Chicago, United States
Poster de conférence hal-02330837v1
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New 3-hit model of schizophrenia: behavioral and electrophysiological investigations

Solenn Percelay , Valentine Bouet , Jean-Marie Billard , Thomas Freret , Michel Boulouard
23ème journée de LARC, Sep 2019, Nantes, France. ⟨10.4103/ipj.ipj_30_15⟩
Poster de conférence hal-02363078v1
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D-serine is involved in the β-amyloid-related pathophysiology in Alzheimer’s disease

E Ploux , L. Gorisse , I Radzishevsky , H Wolosker , T Freret
14eme Colloque de la Société des Neurosciences, May 2019, Marseille, France
Poster de conférence hal-02331616v1

Multiparametric and longitudinal characterization of whole-brain irradiation model in the rat

Elodie Pérès , Gwenn Ropars , Fatima-Azzahra Dwiri , Jérôme Toutain , Carole Brunaud
17th European Network for Light Ion Hadron Therapy (ENLIGHT), Jul 2019, Caen, France
Poster de conférence hal-02265960v1
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Combining adverse factors to build a new 3-hit model of schizophrenia

Solenn Percelay , Valentine Bouët , Thomas Freret , Michel Boulouard
XXIIème journées de l'Ecole Doctorale normande de Biologie Intégrétive, Santé, Environnement, Mar 2019, Caen, France. , 2019
Poster de conférence hal-02135476v1
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Mimicking schizophrenia symptoms in mice by combining factors: genetic, early environmental stress and late pharmacological conditioning

Valentine Bouët , Solenn Percelay , Nicole Turnbull , Thomas Freret , Michel Boulouard
NeuroFrance, May 2019, Marseille, France
Poster de conférence hal-02492831v1
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A robust link between d-serine and amyloid pathology in a mouse model

E Ploux , L. Gorisse , I Radzishevsky , H Wolosker , Thomas Freret
4th International Conference of D-Amino Acid Research, Sep 2019, Tokyo, Japan
Poster de conférence hal-02331029v1
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D-serine contributes to β-amyloid-dependant pathophysiology in Alzheimer’s disease

J-M Billard , E Ploux , L. Gorisse , T Freret
11th FENS Forum of Neuroscience, Jun 2018, Berlin, Germany
Poster de conférence hal-02331264v1
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New mouse model of schizophrenia: "3 hits" model, genetic and environmental factors

Solenn Percelay , Valentine Bouët , Thomas Freret , Michel Boulouard
XXIème journées de l'Ecole Doctorale normande de Biologie Intégrative, Santé, Environnement, Mar 2018, Rouen, France. 2018
Poster de conférence hal-02135458v1
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Schizophrenia: validity of a 3-hit mouse model

Solenn Percelay , Thomas Freret , Boubacar Diarra , Nicolas Delcroix , Elise Leroux
11th Federation of European Neuroscience Societies Forum of Neuroscience, Jul 2018, Berlin, Germany. , 2018
Poster de conférence hal-02135529v1

The role of serotonin 5-HT7 receptors in spatial navigation in the mouse

Gregory Beaudet , Christelle Jozet-Alves , Morgane Chrétien , Thomas Freret , Pascale Schumann-Bard
18ème journée de l’Ecole doctorale EdnBISE, Mar 2015, Rouen, France
Poster de conférence hal-02436408v1

5-HT7 receptors are strongly implicated in allocentric navigation strategy in mice

Gregory Beaudet , Christelle Jozet-Alves , Thomas Freret , Pascale Schumann-Bard , Valentine Bouet
19ème Congrès de la Société Française de Pharmacologie et de Thérapeutique, Apr 2015, Caen, France
Poster de conférence hal-02436415v1