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Number of documents

92

Thomas FRERET


Journal articles77 documents

  • Glenn Dallérac, Xia Li, Pierre Lecouflet, Nadège Morisot, Silvia Sacchi, et al.. Dopaminergic neuromodulation of prefrontal cortex activity requires the NMDA receptor coagonist d-serine. Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (23), pp.e2023750118. ⟨10.1073/pnas.2023750118⟩. ⟨hal-03277751⟩
  • Glenn Dallérac, Xia Li, Pierre Lecouflet, Nadège Morisot, Silvia Sacchi, et al.. Dopaminergic neuromodulation of prefrontal cortex activity requires the NMDA receptor co-agonist D-serine. Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, ⟨10.1073/pnas.2023750118⟩. ⟨hal-03331836⟩
  • Pierre Lecouflet, Candice Roux, B Potier, Marianne Leger, Elie Brunet, et al.. Interplay between 5-HT4 receptors and GABAergic system within CA1 hippocampal synaptic plasticity. Cerebral Cortex, Oxford University Press (OUP), 2021, 31 (1), pp.694-701. ⟨10.1093/cercor/bhaa253⟩. ⟨hal-03371418⟩
  • Solenn Percelay, Jean-Marie Billard, Thomas Freret, Annie Andrieux, Michel Boulouard, et al.. Functional Dysregulations in CA1 Hippocampal Networks of a 3-Hit Mouse Model of Schizophrenia. International Journal of Molecular Sciences, MDPI, 2021, 22 (5), pp.2644. ⟨10.3390/ijms22052644⟩. ⟨hal-03238069⟩
  • Candice Roux, Marianne Leger, Thomas Freret. Memory Disorders Related to Hippocampal Function: The Interest of 5-HT4Rs Targeting. International Journal of Molecular Sciences, MDPI, 2021, 22 (21), pp.12082. ⟨10.3390/ijms222112082⟩. ⟨hal-03471906⟩
  • Thomas Freret, Stacy Largilliere, Gerald Nee, Melanie Coolzaet, Sophie Corvaisier, et al.. Fast Anxiolytic-Like Effect Observed in the Rat Conditioned Defensive Burying Test, after a Single Oral Dose of Natural Protein Extract Products. Nutrients, MDPI, 2021, 13 (7), pp.2445. ⟨10.3390/nu13072445⟩. ⟨hal-03471908⟩
  • François-Xavier Toublet, Julien Lalut, Bérénice Hatat, Cédric Lecoutey, Audrey Davis, et al.. Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer’s disease. European Journal of Medicinal Chemistry, Elsevier, 2021, 210, pp.113059. ⟨10.1016/j.ejmech.2020.113059⟩. ⟨hal-03082877⟩
  • Christophe Rochais, Cédric Lecoutey, Katia Hamidouche, Patrizia Giannoni, Florence Gaven, et al.. Donecopride, a Swiss army knife with potential interest against Alzheimer's disease. British Journal of Pharmacology, Wiley, In press, 177 (9), pp.1988-2005. ⟨10.1111/bph.14964⟩. ⟨hal-02428730⟩
  • Solenn Percelay, Marc Since, S. Lagadu, Thomas Freret, Valentine Bouet, et al.. Antipsychotic lurasidone: Behavioural and pharmacokinetic data in C57BL/6 mice. Pharmacology Biochemistry and Behavior, Elsevier, 2020, 194, pp.172933. ⟨10.1016/j.pbb.2020.172933⟩. ⟨hal-03602034⟩
  • Pierre Lecouflet, Candice M. Roux, Brigitte Potier, Marianne Leger, Elie Brunet, et al.. Interplay between 5-HT4 Receptors and GABAergic System within CA1 Hippocampal Synaptic Plasticity. Cerebral Cortex, Oxford University Press (OUP), 2020, 31 (1), pp.694-701. ⟨10.1093/cercor/bhaa253⟩. ⟨hal-03040826⟩
  • E. Ploux, T Freret, Jean-Marie Billard. D-serine in physiological and pathological brain aging. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020, pp.140542. ⟨10.1016/j.bbapap.2020.140542⟩. ⟨hal-02947335⟩
  • Lou Rizzolo, Marianne Leger, Sophie Corvaisier, Mathilde Groussard, Hervé Platel, et al.. Long-Term Music Exposure Prevents Age-Related Cognitive Deficits in Rats Independently of Hippocampal Neurogenesis. Cerebral Cortex, Oxford University Press (OUP), 2020, 31 (1), pp.620-634. ⟨10.1093/cercor/bhaa247⟩. ⟨hal-03019700⟩
  • Eva Ploux, Valentine Bouet, Inna Radzishevsky, Herman Wolosker, Thomas Freret, et al.. Serine Racemase Deletion Affects the Excitatory/Inhibitory Balance of the Hippocampal CA1 Network. International Journal of Molecular Sciences, MDPI, 2020, 21 (24), pp.9447. ⟨10.3390/ijms21249447⟩. ⟨hal-03072318⟩
  • Tristan Martin, Yves Dauvilliers, Ouma-Chandrou Koumar, Valentine Bouet, Thomas Freret, et al.. Author Correction: Dual orexin receptor antagonist induces changes in core body temperature in rats after exercise. Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.6030. ⟨10.1038/s41598-020-62685-6⟩. ⟨hal-03518966⟩
  • Tristan Martin, Yves Dauvilliers, Ouma-Chandrou Koumar, Valérie Bouet, Thomas Freret, et al.. Dual orexin receptor antagonist induces changes in core body temperature in rats after exercise. Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.18432. ⟨10.1038/s41598-019-54826-3⟩. ⟨hal-02400711⟩
  • Bérénice Hatat, Samir Yahiaoui, Cédric Lecoutey, Audrey Davis, Thomas Freret, et al.. A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT4R) Agonist and Serotonergic Subtype 6 Receptor (5-HT6R) Inverse Agonist Activities, With a Potential Interest Against Alzheimer’s Disease. Frontiers in Aging Neuroscience, Frontiers, 2019, 11, pp.148. ⟨10.3389/fnagi.2019.00148⟩. ⟨hal-02399864⟩
  • François-Xavier Toublet, Cédric Lecoutey, Julien Lalut, Bérénice Hatat, Audrey Davis, et al.. Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer’s Disease. Molecules, MDPI, 2019, 24 (15), pp.2786. ⟨10.3390/molecules24152786⟩. ⟨hal-02399906⟩
  • Jean-Marie Billard, Thomas Freret. Asc-1 transporter activation: an alternative to rescue age-related alterations in functional plasticity at rat hippocampal CA3/CA1 synapses. Journal of Neurochemistry, Wiley, 2018, 147 (4), pp.514-525. ⟨10.1111/jnc.14586⟩. ⟨hal-02135230⟩
  • Hassina Belblidia, Marianne Leger, Abdelmalek Abdelouadoud, Anne Quiedeville, Floriane Calocer, et al.. Characterizing age-related decline of recognition memory and brain activation profile in mice. Experimental Gerontology, Elsevier, 2018, 106, pp.222-231. ⟨10.1016/j.exger.2018.03.006⟩. ⟨hal-01733066⟩
  • Eva Lhuissier, Juliette Aury-Landas, Valentine Bouët, Céline Bazille, Yohann Repesse, et al.. Evaluation of the impact of S-adenosylmethionine-dependent methyltransferase inhibitor, 3-deazaneplanocin A, on tissue injury and cognitive function in mice. Oncotarget, Impact journals, 2018, 9 (29), pp.20698 - 20708. ⟨10.18632/oncotarget.25062⟩. ⟨hal-01796395⟩
  • Anouk Schrantee, Jordi Tremoleda, Marzena Wylezinska-Arridge, Valentine Bouet, Peter Hesseling, et al.. Repeated dexamphetamine treatment alters the dopaminergic system and increases the phMRI response to methylphenidate. PLoS ONE, Public Library of Science, 2017, 12 (2), pp.e0172776. ⟨10.1371/journal.pone.0172776⟩. ⟨hal-02135218⟩
  • Gregory Beaudet, Christelle Jozet-Alves, Rachel Asselot, Pascale Schumann-Bard, Thomas Freret, et al.. Deletion of the serotonin receptor type 7 disrupts the acquisition of allocentric but not egocentric navigation strategies in mice. Behavioural Brain Research, Elsevier, 2017, 320 (1), pp.179 - 185. ⟨10.1016/j.bbr.2016.12.006⟩. ⟨hal-01472663⟩
  • G. Beaudet, E. Paizanis, F. Zoratto, E. Lacivita, M. Leopoldo, et al.. LP-211, a selective 5-HT 7 receptor agonist, increases novelty-preference and promotes risk-prone behavior in rats. Synapse, Wiley-Blackwell, 2017, 71 (12), pp.e21995. ⟨10.1002/syn.21995⟩. ⟨hal-02193575⟩
  • Thomas Freret, Véronique Lelong-Boulouard, Pierre Lecouflet, Katia Hamidouche, François Dauphin, et al.. Co-modulation of an allosteric modulator of nicotinic receptor-cholinesterase inhibitor (galantamine) and a 5-HT4 receptor agonist (RS-67333): effect on scopolamine-induced memory deficit in the mouse. Psychopharmacology, Springer Verlag, 2017, 234 (15), pp.2365-2374. ⟨10.1007/s00213-017-4664-z⟩. ⟨hal-02135214⟩
  • Samir Yahiaoui, Katia Hamidouche, Céline Ballandonne, Audrey Davis, Jana Sopkova-de Oliveira Santos, et al.. Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT 4 R) partial agonist and 5-HT 6 R antagonist activities, as potential treatment of Alzheimer’s disease. European Journal of Medicinal Chemistry, Elsevier, 2016, 121, pp.283-293. ⟨10.1016/j.ejmech.2016.05.048⟩. ⟨hal-02043759⟩
  • G Beaudet, S Valable, J Bourgine, V Lelong-Boulouard, L Lanfumey, et al.. Long-Lasting Effects of Chronic Intermittent Alcohol Exposure in Adolescent Mice on Object Recognition and Hippocampal Neuronal Activity.. Alcoholism: Clinical and Experimental Research, Wiley, 2016, 40 (12), pp.2591-2603. ⟨10.1111/acer.13256⟩. ⟨hal-01576066⟩
  • Anne Quiedeville, Michel Boulouard, Katia Hamidouche, Virginie da Silva Costa-Aze, Gerald Nee, et al.. Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances. Behavioural Brain Research, Elsevier, 2015, 293, pp.10-17. ⟨10.1016/j.bbr.2015.07.020⟩. ⟨hal-02043824⟩
  • Christophe Liet, Fella Amenouche, Thomas Freret, Michel Boulouard, Benoit Mauvieux, et al.. Effects of acute administration of melatonin on attentional, executive, and working memory processes in rats. Fundamental and Clinical Pharmacology, Wiley, 2015, 29 (5), pp.472-477. ⟨10.1111/fcp.12134⟩. ⟨hal-02193380⟩
  • Thomas Freret, Pierrette Gaudreau, Pascale Schumann-Bard, Jean-Marie Billard, Aurel Popa-Wagner. Mechanisms underlying the neuroprotective effect of brain reserve against late life depression. Journal of Neural Transmission, Springer Verlag, 2015, 122 (S1), pp.55-61. ⟨10.1007/s00702-013-1154-2⟩. ⟨hal-02325092⟩
  • K. van Der Marel, V. Bouet, G.F. Meerhoff, T. Freret, M. Boulouard, et al.. Effects of long-term methylphenidate treatment in adolescent and adult rats on hippocampal shape, functional connectivity and adult neurogenesis. Neuroscience, Elsevier - International Brain Research Organization, 2015, 309, pp.243-258. ⟨10.1016/j.neuroscience.2015.04.044⟩. ⟨hal-02193376⟩
  • Christophe Rochais, Cédric Lecoutey, Florence Gaven, Patrizia Giannoni, Katia Hamidouche, et al.. Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT 4 R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride. Journal of Medicinal Chemistry, American Chemical Society, 2015, 58 (7), pp.3172-3187. ⟨10.1021/acs.jmedchem.5b00115⟩. ⟨hal-02043873⟩
  • Gregory Beaudet, Valentine Bouet, Christelle Jozet-Alves, Pascale Schumann-Bard, Francois Dauphin, et al.. Spatial memory deficit across aging: current insights of the role of 5-HT7 receptors. Frontiers in Behavioral Neuroscience, Frontiers, 2015, 8, pp.448. ⟨10.3389/fnbeh.2014.00448⟩. ⟨hal-01472654⟩
  • Marianne Leger, Eleni Paizanis, Kwamivi Dzahini, Anne Quiedeville, Valentine Bouet, et al.. Environmental Enrichment Duration Differentially Affects Behavior and Neuroplasticity in Adult Mice. Cerebral Cortex, Oxford University Press (OUP), 2015, 25 (11), pp.4048-4061. ⟨10.1093/cercor/bhu119⟩. ⟨hal-02135292⟩
  • Elise Rousseau, Michael Joubert, Géraldine Trzepla, Jean Jacques Parienti, Thomas Freret, et al.. Usefulness of Time-Point Serum Cortisol and ACTH Measurements for the Adjustment of Glucocorticoid Replacement in Adrenal Insufficiency. PLoS ONE, Public Library of Science, 2015, 10 (8), pp.e0135975. ⟨10.1371/journal.pone.0135975⟩. ⟨hal-02190958⟩
  • Hassina Belblidia, Abdelmalek Abdelouadoud, Christelle Jozet-Alves, Hélène Dumas, Thomas Freret, et al.. Time decay of object, place and temporal order memory in a paradigm assessing simultaneously episodic-like memory components in mice. Behavioural Brain Research, Elsevier, 2015, 286, pp.80--84. ⟨10.1016/j.bbr.2015.02.043⟩. ⟨hal-01472655⟩
  • Delphine Karila, Thomas Freret, Valentine Bouet, Michel Boulouard, Patrick Dallemagne, et al.. Therapeutic Potential of 5-HT 6 Receptor Agonists. Journal of Medicinal Chemistry, American Chemical Society, 2015, 58 (20), pp.7901-7912. ⟨10.1021/acs.jmedchem.5b00179⟩. ⟨hal-02043781⟩
  • Alban Lepailleur, Thomas Freret, Stéphane Lemaître, Michel Boulouard, François Dauphin, et al.. Dual Histamine H3R/Serotonin 5-HT4R Ligands with Antiamnesic Properties: Pharmacophore-Based Virtual Screening and Polypharmacology.. Journal of Chemical Information and Modeling, American Chemical Society, 2014, 54 (6), pp.1773-1784. ⟨hal-01064770⟩
  • Cédric Lecoutey, Damien Hedou, Thomas Freret, Patrizia Giannoni, Florence Gaven, et al.. Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment. Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (36), pp.E3825--30. ⟨10.1073/pnas.1410315111⟩. ⟨hal-01800439v2⟩
  • Javier Becerril-Ortega, Karim Bordji, Thomas Freret, Travis Rush, Alain Buisson. Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease. Neurobiology of Aging, Elsevier, 2014, 35 (10), pp.2288 - 2301. ⟨10.1016/j.neurobiolaging.2014.04.019⟩. ⟨hal-01626647⟩
  • Véronique Paban, Jean-Marie Billard, Valentine Bouet, Thomas Freret, Michel Boulouard, et al.. Genomic transcriptional profiling in LOU/C/Jall rats identifies genes for successful aging. Brain Structure and Function, Springer Verlag, 2013, 218 (6), pp.1501-1512. ⟨10.1007/s00429-012-0472-8⟩. ⟨hal-02325134⟩
  • Marianne Leger, Anne Quiedeville, Valentine Bouet, Benoît Haelewyn, Michel Boulouard, et al.. Object recognition test in mice. Nature Protocols, Nature Publishing Group, 2013, 8 (12), pp.2531-2537. ⟨10.1038/nprot.2013.155⟩. ⟨hal-02135259⟩
  • Marc Since, Thomas Freret, Gerald Nee, Thierry Terme, Patrice Vanelle, et al.. New orally effective 3-(2-nitro)phenylpropanamide analgesic derivatives: Synthesis and antinociceptive evaluation. European Journal of Medicinal Chemistry, Elsevier, 2013, 69, pp.728--734. ⟨10.1016/j.ejmech.2013.08.041⟩. ⟨hal-01460473⟩
  • S. Besnard, M. L. Machado, G. Vignaux, M. Boulouard, A. Coquerel, et al.. Influence of vestibular input on spatial and nonspatial memory and on hippocampal NMDA receptors.. Hippocampus, Wiley, 2012, 22 (4), pp.814-26. ⟨10.1002/hipo.20942⟩. ⟨hal-00866441⟩
  • T. Freret, Jean-Marie Billard, P. Schumann-Bard, P. Dutar, F. Dauphin, et al.. Rescue of cognitive aging by long-lasting environmental enrichment exposure initiated before median lifespan. Neurobiology of Aging, Elsevier, 2012, 33 (5), pp.1005.e1-1005.e10. ⟨10.1016/j.neurobiolaging.2011.09.028⟩. ⟨hal-02325180⟩
  • Maïte Hotte, François Dauphin, Thomas Freret, Michel Boulouard, Guenaëlle Levallet. A biphasic and brain-region selective down-regulation of cyclic adenosine monophosphate concentrations supports object recognition in the rat.. PLoS ONE, Public Library of Science, 2012, 7 (2), pp.e32244. ⟨10.1371/journal.pone.0032244⟩. ⟨hal-00862771⟩
  • Véronique Paban, Jean-Marie Billard, Valentine Bouet, Thomas Freret, Michel Boulouard, et al.. Genomic transcriptional profiling in LOU/C/Jall rats identifies genes for successful aging.. Brain Structure and Function, Springer Verlag, 2012, 218 (6), pp.1501-1512. ⟨10.1007/s00429-012-0472-8⟩. ⟨hal-00862299⟩
  • M. L. Machado, N. Kroichvili, T. Freret, B. Philoxène, V. Lelong-Boulouard, et al.. Spatial and non-spatial performance in mutant mice devoid of otoliths.. Neuroscience Letters, Elsevier, 2012, 522 (1), pp.57-61. ⟨10.1016/j.neulet.2012.06.016⟩. ⟨hal-00866394⟩
  • Marianne Leger, Valentine Bouet, Thomas Freret, Anne-Sophie Darmaillacq, Matthieu Dacher, et al.. Environmental enrichment improves recent but not remote memory in association with a modified brain metabolic activation profile in adult mice.. Behavioural Brain Research, Elsevier, 2012, 228 (1), pp.22-9. ⟨10.1016/j.bbr.2011.11.022⟩. ⟨hal-00862779⟩
  • Annelise Letourneur, Thomas Freret, Simon Roussel, Michel Boulouard, Didier Divoux, et al.. Maternal hypertension during pregnancy modifies the response of the immature brain to hypoxia-ischemia: sequential MRI and behavioral investigations.. Experimental Neurology, Elsevier, 2012, 233 (1), pp.264-72. ⟨10.1016/j.expneurol.2011.10.014⟩. ⟨hal-00862822⟩
  • Valentine Bouet, Anne Klomp, Thomas Freret, Marzena Wylezinska-Arridge, Jordi Lopez-Tremoleda, et al.. Age-dependent effects of chronic fluoxetine treatment on the serotonergic system one week following treatment.. Psychopharmacology, Springer Verlag, 2012, 221 (2), pp.329-39. ⟨10.1007/s00213-011-2580-1⟩. ⟨hal-00862306⟩
  • Thomas Freret, Valentine Bouet, Anne Quiedeville, Gerald Nee, Patrick Dallemagne, et al.. Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT4 receptor activation (RS67333) on object recognition in mice.. Behavioural Brain Research, Elsevier, 2012, 230, pp.304-308. ⟨hal-00821461⟩
  • Claire Leconte, Marianne Léger, Michel Boulouard, Emmanuelle Tixier, Thomas Fréret, et al.. Repeated mild hypoxic exposures decrease anxiety-like behavior in the adult mouse together with an increased brain adrenomedullin gene expression.. Behavioural Brain Research, Elsevier, 2012, 230 (1), pp.78-84. ⟨10.1016/j.bbr.2012.01.054⟩. ⟨hal-00862777⟩
  • Marianne Leger, Anne Quiedeville, Eleni Paizanis, Sharuja Natkunarajah, Thomas Freret, et al.. Environmental enrichment enhances episodic-like memory in association with a modified neuronal activation profile in adult mice.. PLoS ONE, Public Library of Science, 2012, 7 (10), pp.e48043. ⟨10.1371/journal.pone.0048043⟩. ⟨hal-00862786⟩
  • Isabelle Loubinoux, Golo Kronenberg, Matthias Endres, Pascale Schumann-Bard, Thomas Freret, et al.. Post-stroke depression: mechanisms, translation and therapy.. Journal of Cellular and Molecular Medicine, Wiley Open Access, 2012, 16 (9), pp.1961-9. ⟨10.1111/j.1582-4934.2012.01555.x⟩. ⟨hal-00862834⟩
  • Thomas Freret, Valentine Bouet, Anne Quiedeville, Gérald Nee, Patrick Dallemagne, et al.. Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice.. Behavioural Brain Research, Elsevier, 2012, 230 (1), pp.304-8. ⟨10.1016/j.bbr.2012.02.012⟩. ⟨hal-00862757⟩
  • M. L. Machado, V. Lelong-Boulouard, P. F. Smith, T. Freret, B. Philoxene, et al.. Influence of anxiety in spatial memory impairments related to the loss of vestibular function in rat.. Neuroscience, Elsevier - International Brain Research Organization, 2012, 218, pp.161-9. ⟨10.1016/j.neuroscience.2012.05.029⟩. ⟨hal-00866396⟩
  • T. Freret, J.-M. Billard, P. Schumann-Bard, P. Dutar, F. Dauphin, et al.. Rescue of cognitive aging by long-lasting environmental enrichment exposure initiated before median lifespan.. Neurobiol Aging, 2012, 33 (5), pp.1005.e1-10. ⟨10.1016/j.neurobiolaging.2011.09.028⟩. ⟨hal-00866400⟩
  • Lydia Danglot, Thomas Freret, Nicolas Le Roux, Nicolas Narboux Nême, Andrea Burgo, et al.. Vezatin is essential for dendritic spine morphogenesis and functional synaptic maturation.. Journal of Neuroscience, Society for Neuroscience, 2012, 32 (26), pp.9007-22. ⟨10.1523/JNEUROSCI.3084-11.2012⟩. ⟨hal-00776396⟩
  • Valentine Bouet, Thomas Freret, Patrick Dutar, Jean-Marie Billard, Michel Boulouard. Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals.. Mechanisms of Ageing and Development, Elsevier, 2011, 132 (5), pp.240-8. ⟨10.1016/j.mad.2011.04.006⟩. ⟨hal-00862993⟩
  • Thomas Freret, Pascale Schumann-Bard, Michel Boulouard, Valentine Bouet. On the importance of long-term functional assessment after stroke to improve translation from bench to bedside.. Experimental and Translational Stroke Medicine, BioMed Central, 2011, 3, pp.6. ⟨10.1186/2040-7378-3-6⟩. ⟨hal-00862997⟩
  • Valentine Bouet, Thomas Freret, Patrick Dutar, Jean-Marie Billard, Michel Boulouard. Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals. Mechanisms of Ageing and Development, Elsevier, 2011, 132 (5), pp.240-248. ⟨10.1016/j.mad.2011.04.006⟩. ⟨hal-02325196⟩
  • Valentine Bouet, Blandine Lecrux, Gwenaelle Tran, Thomas Freret. Effect of pre- versus post-weaning environmental disturbances on social behaviour in mice.. Neuroscience Letters, Elsevier, 2011, 488 (2), pp.221-4. ⟨10.1016/j.neulet.2010.11.033⟩. ⟨hal-00862841⟩
  • Valentine Bouet, Thomas Freret, Steve Ankri, Madeleine Bezault, Sylvain Renolleau, et al.. Predicting sensorimotor and memory deficits after neonatal ischemic stroke with reperfusion in the rat.. Behavioural Brain Research, Elsevier, 2010, 212 (1), pp.56-63. ⟨10.1016/j.bbr.2010.03.043⟩. ⟨hal-00863083⟩
  • Thomas Freret, Valentine Bouet, Claire Leconte, Simon Roussel, Laurent Chazalviel, et al.. Behavioral deficits after distal focal cerebral ischemia in mice: Usefulness of adhesive removal test.. Behavioral Neuroscience, American Psychological Association, 2009, 123 (1), pp.224-30. ⟨10.1037/a0014157⟩. ⟨hal-00863264⟩
  • Claire Leconte, Emmanuelle Tixier, Thomas Freret, Jérôme Toutain, Romaric Saulnier, et al.. Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse.. Stroke, American Heart Association, 2009, 40 (10), pp.3349-55. ⟨10.1161/STROKEAHA.109.557314⟩. ⟨hal-00863295⟩
  • Valentine Bouet, Michel Boulouard, Jérôme Toutain, Didier Divoux, Myriam Bernaudin, et al.. The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice.. Nature Protocols, Nature Publishing Group, 2009, 4 (10), pp.1560-4. ⟨10.1038/nprot.2009.125⟩. ⟨hal-00863258⟩
  • Inmaculada Berenguer, Noureddine El Aouad, Sebastián Andujar, Vanessa Romero, Fernando Suvire, et al.. Tetrahydroisoquinolines as dopaminergic ligands: 1-Butyl-7-chloro-6-hydroxy-tetrahydroisoquinoline, a new compound with antidepressant-like activity in mice.. Bioorganic and Medicinal Chemistry, Elsevier, 2009, 17 (14), pp.4968-80. ⟨10.1016/j.bmc.2009.05.079⟩. ⟨hal-00863255⟩
  • Elise Esneault, Emilie Pacary, Dauphou Eddi, Thomas Freret, Emmanuelle Tixier, et al.. Combined therapeutic strategy using erythropoietin and mesenchymal stem cells potentiates neurogenesis after transient focal cerebral ischemia in rats.. Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group, 2008, 28 (9), pp.1552-63. ⟨10.1038/jcbfm.2008.40⟩. ⟨hal-00863330⟩
  • Thomas Freret, Valentine Bouet, Jérôme Toutain, Romaric Saulnier, Palma Pro-Sistiaga, et al.. Intraluminal thread model of focal stroke in the non-human primate. Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group, 2008, 28 (4), pp.786-96. ⟨10.1038/sj.jcbfm.9600575⟩. ⟨hal-00863332⟩
  • Benoît Haelewyn, Thomas Freret, Emilie Pacary, Pascale Schumann-Bard, Michel Boulouard, et al.. Long-term evaluation of sensorimotor and mnesic behaviour following striatal NMDA-induced unilateral excitotoxic lesion in the mouse. Behavioural Brain Research, Elsevier, 2007, 178, pp.235-243. ⟨10.1016/j.bbr.2006.12.023⟩. ⟨hal-00867870⟩
  • Valentine Bouët, Thomas Freret, Jérôme Toutain, Didier Divoux, Michel Boulouard, et al.. Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse.. Experimental Neurology, Elsevier, 2007, 203 (2), pp.555-67. ⟨10.1016/j.expneurol.2006.09.006⟩. ⟨hal-00178296⟩
  • Benoît Haelewyn, Thomas Freret, Emilie Pacary, Pascale Schumann-Bard, Michel Boulouard, et al.. Long-term evaluation of sensorimotor and mnesic behaviour following striatal NMDA-induced unilateral excitotoxic lesion in the mouse.. Behavioural Brain Research, Elsevier, 2007, 178 (2), pp.235-43. ⟨10.1016/j.bbr.2006.12.023⟩. ⟨hal-00178443⟩
  • Y. Tang, E. Pacary, T. Freret, D. Divoux, E. Petit, et al.. Effect of hypoxic preconditioning on brain genomic response before and following ischemia in the adult mouse: identification of potential neuroprotective candidates for stroke. Neurobiology of Disease, Elsevier, 2006, 21, pp.18-28. ⟨hal-00018635⟩
  • T. Freret, S. Valable, L. Chazalviel, R. Saulnier, E.T. Mackenzie, et al.. Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat.. European Journal of Neuroscience, Wiley, 2006, 23, pp.1757-1765. ⟨hal-00023477⟩
  • Valentine Bouet, Thomas Freret, J. Toutain, Didier Divoux, Michel Boulouard, et al.. Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse. Experimental Neurology, Elsevier, 2006, 203, pp.55-567. ⟨10.1016/j.expneurol.2006.09.006⟩. ⟨hal-00867774⟩
  • Thomas Freret, Laurent Chazalviel, Simon Roussel, Myriam Bernaudin, Pascale Schumann-Bard, et al.. Long-term functional outcome following transient middle cerebral artery occlusion in the rat: correlation between brain damage and behavioral impairment.. Behavioral Neuroscience, American Psychological Association, 2006, 120 (6), pp.1285-98. ⟨10.1037/0735-7044.120.6.1285⟩. ⟨hal-00865366⟩
  • Thomas Freret, Samuel Valable, Laurent Chazalviel, Romaric Saulnier, Eric T Mackenzie, et al.. Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat.. European Journal of Neuroscience, Wiley, 2006, 23 (7), pp.1757-65. ⟨10.1111/j.1460-9568.2006.04699.x⟩. ⟨hal-00865370⟩

Conference papers1 document

  • Aurélie Malzert-Fréon, Anne-Claire Groo, Siham Hedir, Marc Since, Martina de Pascale, et al.. Evaluation préclinique de nanoémulsions polyvalentes comme vecteurs d’un nouvel inhibiteur de Mcl-1, le Pyridoclax : application au traitement des cancers de l’ovaire (PYRINANO). 10émes journées scientifiques du cancéropole nord-ouest, May 2017, Deauville, France. ⟨hal-02295794⟩

Poster communications13 documents

  • E Ploux, L. Gorisse, I Radzishevsky, H Wolosker, Thomas Freret, et al.. A robust link between d-serine and amyloid pathology in a mouse model. 4th International Conference of D-Amino Acid Research, Sep 2019, Tokyo, Japan. ⟨hal-02331029⟩
  • T. Freret, E Ploux, L. Gorisse, I Radzishevsky, H Wolosker, et al.. Impact of d-serine depletion in the β-amyloid cascade related to Alzheimer’s disease. Annual Meeting of the Society for Neuroscience (SFN), Oct 2019, Chicago, United States. ⟨hal-02330837⟩
  • F Menager, Solenn Percelay, T. Freret, M. Boulouard, Jean-Marie Billard, et al.. Altering glutamate transmission in combination with an early post-natal stress to mimic schizophrenia in male and female mice. Journée Normande de Recherche Biomédicale, Nov 2019, Caen, France. ⟨hal-02363095⟩
  • Solenn Percelay, Valentine Bouet, Jean-Marie Billard, Thomas Freret, Michel Boulouard. New 3-hit model of schizophrenia: behavioral and electrophysiological investigations. 23ème journée de LARC, Sep 2019, Nantes, France. ⟨10.4103/ipj.ipj_30_15⟩. ⟨hal-02363078⟩
  • E Ploux, L. Gorisse, I Radzishevsky, H Wolosker, T Freret, et al.. D-serine is involved in the β-amyloid-related pathophysiology in Alzheimer’s disease. 14eme Colloque de la Société des Neurosciences, May 2019, Marseille, France. ⟨hal-02331616⟩
  • Solenn Percelay, Valentine Bouët, Thomas Freret, Michel Boulouard. Combining adverse factors to build a new 3-hit model of schizophrenia. XXIIème journées de l'Ecole Doctorale normande de Biologie Intégrétive, Santé, Environnement, Mar 2019, Caen, France. 2019. ⟨hal-02135476⟩
  • Valentine Bouët, Solenn Percelay, Nicole Turnbull, Thomas Freret, Michel Boulouard. Mimicking schizophrenia symptoms in mice by combining factors: genetic, early environmental stress and late pharmacological conditioning. NeuroFrance, May 2019, Marseille, France. ⟨hal-02492831⟩
  • Elodie Pérès, Gwenn Ropars, Fatima-Azzahra Dwiri, Jérôme Toutain, Carole Brunaud, et al.. Multiparametric and longitudinal characterization of whole-brain irradiation model in the rat. 17th European Network for Light Ion Hadron Therapy (ENLIGHT), Jul 2019, Caen, France. ⟨hal-02265960⟩
  • J-M Billard, E Ploux, L. Gorisse, T Freret. D-serine contributes to β-amyloid-dependant pathophysiology in Alzheimer’s disease. 11th FENS Forum of Neuroscience, Jun 2018, Berlin, Germany. ⟨hal-02331264⟩
  • Solenn Percelay, Valentine Bouët, Thomas Freret, Michel Boulouard. New mouse model of schizophrenia: "3 hits" model, genetic and environmental factors. XXIème journées de l'Ecole Doctorale normande de Biologie Intégrative, Santé, Environnement, Mar 2018, Rouen, France. 2018. ⟨hal-02135458⟩
  • Solenn Percelay, Thomas Freret, Boubacar Diarra, Nicolas Delcroix, Elise Leroux, et al.. Schizophrenia: validity of a 3-hit mouse model. 11th Federation of European Neuroscience Societies Forum of Neuroscience, Jul 2018, Berlin, Germany. 2018. ⟨hal-02135529⟩
  • Gregory Beaudet, Christelle Jozet-Alves, Morgane Chrétien, Thomas Freret, Pascale Schumann-Bard, et al.. The role of serotonin 5-HT7 receptors in spatial navigation in the mouse. 18ème journée de l’Ecole doctorale EdnBISE, Mar 2015, Rouen, France. ⟨hal-02436408⟩
  • Gregory Beaudet, Christelle Jozet-Alves, Thomas Freret, Pascale Schumann-Bard, Valentine Bouet, et al.. 5-HT7 receptors are strongly implicated in allocentric navigation strategy in mice. 19ème Congrès de la Société Française de Pharmacologie et de Thérapeutique, Apr 2015, Caen, France. ⟨hal-02436415⟩

Patents1 document

  • Patrick Dallemagne, Christophe Rochais, Cédric Lecoutey, Michel Boulouard, Thomas Freret. Acetylcholinesterase Inhibitor Compounds and 5ht4 Serotonergic Receptor Agonists, with Promnesia Effect, Methods for the Preparation Thereof and Pharmaceutical Compositions Containing Same. France, Patent n° : WO2014195593 (A2). 2014. ⟨hal-02042939⟩