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Thomas Boraud

8
Documents

Présentation

Thomas Boraud's research interest focused on the neural networks of decision making, skill and procedural learning and associated pathophysiology (Parkinson's disease, OCD, Dystonia, etc…). He tackles this topic with a phylogenetic approach in order to unravel how the system evolved in different taxa (amphibians, birds, rodents and non-human primates) from an original blueprint. After a Marie Curie Fellowship at the Hebrew University of Jerusalem, he secured a tenured position (Charge de Recherche) in the CNRS in 2001 and became Directeur de Recherche in 2008. He took the head of the Institute of Neurodegenerative Diseases (IMN, UMR CNRS 5293) in September 2020. Since 2010, his involvement in research brings him to develop a growing interest in the ethical responsibility of scientists toward society regarding scientific uncertainty and the development of the Neuro-essentialism. He published a book toward general public called "Matière à decision" (CNRS editions, Paris, 2015; 2nd ed Biblis, Paris 2017), the second edition has been translated in English (How the Brain Makes Decisions, Oxford University Press, 2020). Thomas Boraud has resumed a clinical activity in 2012 at the University Hospital of Bordeaux dedicated mainly to the follow up of patients included in clinical trials concerning Parkinson's syndromes and Alzheimer disease.

Publications

arthur-leblois
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The globus pallidus orchestrates abnormal network dynamics in a model of Parkinsonism

Brice de La Crompe , Asier Aristieta , Arthur Leblois , Salma Elsherbiny , Thomas Boraud
Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-15352-3⟩
Article dans une revue hal-03010083v1
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A Natural History of Skills

Thomas Boraud , Arthur Leblois , Nicolas P. Rougier
Progress in Neurobiology, 2018, 171, pp.114-124. ⟨10.1016/j.pneurobio.2018.08.003⟩
Article dans une revue hal-01874690v1
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A Long Journey into Reproducible Computational Neuroscience

Meropi Topalidou , Arthur Leblois , Thomas Boraud , Nicolas P. Rougier
Frontiers in Computational Neuroscience, 2015, pp.2. ⟨10.3389/fncom.2015.00030⟩
Article dans une revue hal-01117873v1

Interaction Between Cognitive and Motor Cortico-Basal Ganglia Loops During Decision Making: A Computational Study

Martin Guthrie , Arthur Leblois , André Garenne , Thomas Boraud
Journal of Neurophysiology, 2013
Article dans une revue hal-00828004v1

Late emergence of synchronized oscillatory activity in the pallidum during progressive parkinsonism.

Arthur Leblois , Wassilios Meissner , Bernard Bioulac , Christian E Gross , David Hansel
European Journal of Neuroscience, 2007, 26 (6), pp.1701-1713. ⟨10.1111/j.1460-9568.2007.05777.x⟩
Article dans une revue hal-00174211v1

Competition between feedback loops underlies normal and pathological dynamics in the basal ganglia.

Arthur Leblois , Thomas Boraud , Wassilios Meissner , Hagai Bergman , David Hansel
Journal of Neuroscience, 2006, 26 (13), pp.3567-83. ⟨10.1523/JNEUROSCI.5050-05.2006⟩
Article dans une revue hal-00173766v1

Subthalamic high frequency stimulation resets subthalamic firing and reduces abnormal oscillations.

Wassilios Meissner , Arthur Leblois , David Hansel , Bernard Bioulac , Christian E Gross
Brain - A Journal of Neurology , 2005, 128 (Pt 10), pp.2372-82. ⟨10.1093/brain/awh616⟩
Article dans une revue hal-00173768v1

Competition between feedback loops as the core of a computational model of the basal ganglia

A. Leblois , Thomas Boraud , H. Bergman , D. Hansel
E. Bezard. Recent breakthroughs in basal ganglia research, Nova Publishing, New York, pp.xxx-xxx, 2006
Chapitre d'ouvrage hal-00176394v1