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The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells

Pauline Estupina , Alexandre Fontayne , Jean-Marc Barret , Nathalie Kersual , Olivier Dubreuil , et al.
Oncotarget, 2017, 8 (23), pp.37061-37079. ⟨10.18632/oncotarget.15715⟩
Article dans une revue hal-02379710v1
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The human Mullerian inhibiting substance type II receptor as immunotherapy target for ovarian cancer. Validation using the mAb 12G4

Nathalie Kersual , Véronique Garambois , Thierry Chardès , Jean-Pierre Pouget , Imed Salhi , et al.
mAbs, 2014, 6, pp.1314--26. ⟨10.4161/mabs.29316⟩
Article dans une revue hal-02168055v1
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Examination of HER3 targeting in cancer using monoclonal antibodies

Nadège Gaborit , Ali Abdul-Hai , Maicol Mancini , Moshit Lindzen , Sara Lavi , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (3), pp.839-844. ⟨10.1073/pnas.1423645112⟩
Article dans une revue hal-02276327v1

In vitro antitumoral activity of baculovirus-expressed chimeric recombinant anti-CD4 antibody 13B8.2 on T-cell lymphomas.

Samuel Troadec , Myriam Chentouf , Martine Cérutti , Brigitte Nguyen , Daniel Olive , et al.
Journal of Immunotherapy, 2007, 30 (2), pp.190-202. ⟨10.1097/01.cji.0000211331.61019.26⟩
Article dans une revue hal-00170828v1
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Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies

Timothée David , Aude Mallavialle , Julien Faget , Lindsay B Alcaraz , Marion Lapierre , et al.
Journal for Immunotherapy of Cancer, 2019, 7 (1), pp.29-46. ⟨10.1186/s40425-019-0498-z⟩
Article dans une revue hal-02335397v1
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Quantification of HER1, HER2 and HER3 by time-resolved Förster resonance energy transfer in FFPE triple-negative breast cancer samples

Alexandre Ho-Pun-Cheung , Hervé Bazin , Florence Boissière-Michot , Caroline Mollevi , Joëlle Simony-Lafontaine , et al.
British Journal of Cancer, 2020, 122 (3), pp.397-404. ⟨10.1038/s41416-019-0670-8⟩
Article dans une revue hal-03037393v1
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SPARC in cancer‐associated fibroblasts is an independent poor prognostic factor in non‐metastatic triple‐negative breast cancer and exhibits pro‐tumor activity

Lindsay B Alcaraz , Aude Mallavialle , Caroline Mollevi , Andrei Turtoi , Florence Boissière-Michot , et al.
International Journal of Cancer, 2022, ⟨10.1002/ijc.34345⟩
Article dans une revue hal-03844847v1
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Design and selection of optimal ErbB-targeting bispecific antibodies in pancreatic cancer

Emilia Rabia , Véronique Garambois , Christine Dhommée , Christel Larbouret , Laurie Lajoie , et al.
Frontiers in Immunology, 2023, 14, ⟨10.3389/fimmu.2023.1168444⟩
Article dans une revue hal-04102843v2
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Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy.

Wilhem Leconet , Christel Larbouret , Thierry Chardès , Gaëlle Thomas , Madeline Neiveyans , et al.
Oncogene, 2014, 33 (47), pp.5405-14. ⟨10.1038/onc.2013.487⟩
Article dans une revue inserm-00916587v1
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Biasing HER4 tyrosine kinase signaling with antibodies: Induction of cell death by antibody‐dependent HER4 intracellular domain trafficking

Romain Lanotte , Véronique Garambois , Nadège Gaborit , Christel Larbouret , Astrid Musnier , et al.
Cancer Science, 2020, 111 (7), pp.2508-2525. ⟨10.1111/cas.14458⟩
Article dans une revue hal-03036389v1
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The HER3/ERBB3 receptor: the dark side of the ERBB planet

Christel Larbouret , Nadège Gaborit , Marie-Alix Poul , André Pèlegrin , Thierry Chardès
Médecine/Sciences, 2015, 31 (5), pp.465-468. ⟨10.1051/medsci/20153105002⟩
Article dans une revue hal-02285139v1
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The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

Christophe Le Clorennec , Yassamine Lazrek , Olivier Dubreuil , Christel Larbouret , Marie-Alix Poul , et al.
Oncotarget, 2016, 7 (24), pp.37013-37029. ⟨10.18632/oncotarget.9455⟩
Article dans une revue hal-02297403v1

PIN-bodies: a new class of antibody-like proteins with CD4 specificity derived from the protein inhibitor of neuronal nitric oxide synthase.

Cédric Bès , Samuel Troadec , Myriam Chentouf , Hélène Breton , Anne Dominique Lajoix , et al.
Biochemical and Biophysical Research Communications, 2006, 343 (1), pp.334-44. ⟨10.1016/j.bbrc.2006.02.126⟩
Article dans une revue istex hal-00201221v1
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The human anti-thyroid peroxidase autoantibody repertoire in Graves' and Hashimoto's autoimmune thyroid diseases

Thierry Chardès , Nicolas Chapal , Damien Bresson , Cédric Bès , Véronique Giudicelli , et al.
Immunogenetics, 2002, 54 (3), pp.141-157. ⟨10.1007/s00251-002-0453-9⟩
Article dans une revue istex hal-04335106v1
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Localization of the discontinous immunodominant region recognized by human anti-thyroperoxidase autoantibodies in autoimmune thyroid diseases

Damien Bresson , Martine Cerutti , Gerard Devauchelle , Martine Pugnière , Françoise Roquet , et al.
Journal of Biological Chemistry, 2003, 278 (11), pp.9560-9569. ⟨10.1074/jbc.M211930200⟩
Article dans une revue hal-02682693v1
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Local and systemic cellular immunity following oral infection of mice with Toxoplasma gondii cysts

T Chardès , F Velge-Roussel , Mn Mevelec , F Blaise , D Bout
Annales de Recherches Vétérinaires, 1992, 23 (3), pp.290-291
Article dans une revue hal-00902079v1
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Mucosal vaccination against toxoplasmosis

D Bout , D Buzoni-Gatel , T Chardès , N Debard , Mn Mevelec
Veterinary Research, 1995, 26 (3), pp.214-215
Article dans une revue hal-00902338v1

ANTI-HUMAN-HER3 ANTIBODIES AND USES THEREOF

Yassamine Lazrek , Thierry Chardès , Christel Larbouret , André Pèlegrin
France, Patent n° : WO 2012/156532. 2012
Brevet hal-03706426v1
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Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3

Christophe Le Clorennec , Hervé Bazin , Olivier Dubreuil , Christel Larbouret , Charline Ogier , et al.
Molecular Cancer Therapeutics, 2017, 16 (7), pp.1312-1323. ⟨10.1158/1535-7163.MCT-16-0886⟩
Article dans une revue hal-02434070v1

Anti-Müllerian hormone concentration regulates activin receptor-like kinase-2/3 expression levels with opposing effects on ovarian cancer cell survival

Maëva Chauvin , Véronique Garambois , Sylvie Choblet , Pierre-Emmanuel Colombo , Myriam Chentouf , et al.
International Journal of Oncology, 2021, 59 (1), ⟨10.3892/ijo.2021.5223⟩
Article dans une revue hal-03229123v1
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Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice.

Maha Ladjemi , Thierry Chardes , Stephanie Corgnac , Veronique Garambois , Sebastien Morisseau , et al.
Breast Cancer Research, 2011, 13 (1), pp.R17. ⟨10.1186/bcr2826⟩
Article dans une revue inserm-00649414v1
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A novel Fc-engineered cathepsin D-targeting antibody enhances ADCC, triggers tumor-infiltrating NK cell recruitment, and improves treatment with paclitaxel and enzalutamide in triple-negative breast cancer

Pénélope Desroys Du Roure , Laurie Lajoie , Aude Mallavialle , Lindsay Alcaraz , Hanane Mansouri , et al.
Journal for Immunotherapy of Cancer, 2024, 12 (1), pp.e007135. ⟨10.1136/jitc-2023-007135⟩
Article dans une revue hal-04459385v1
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An auristatin‐based antibody‐drug conjugate targeting HER3 enhances the radiation response in pancreatic cancer

Laura Bourillon , Céline Bourgier , Nadège Gaborit , Véronique Garambois , Eva Lles , et al.
International Journal of Cancer, 2019, 145 (7), pp.1838-1851. ⟨10.1002/ijc.32273⟩
Article dans une revue inserm-02074060v1
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Targeting the NRG1/HER3 pathway in tumor cells and cancer-associated fibroblasts with an anti-neuregulin 1 antibody inhibits tumor growth in pre-clinical models of pancreatic cancer

Charline Ogier , Pierre-Emmanuel Colombo , Corinne Bousquet , Lucile Canterel-Thouennon , Pierre Sicard , et al.
Cancer Letters, 2018, 432, pp.227-236. ⟨10.1016/j.canlet.2018.06.023⟩
Article dans une revue hal-02350723v1
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Synthetic peptides derived from the variable regions of an anti-CD4 monoclonal antibody bind to CD4 and inhibit HIV-1 promoter activation in virus-infected cells

Céline Monnet , Daniel Laune , Jeanny Laroche-Traineau , Martine Biard-Piechaczyk , Laurence Briant , et al.
Journal of Biological Chemistry, 1999, 274 (6), pp.3789-3796. ⟨10.1074/jbc.274.6.3789⟩
Article dans une revue hal-02696615v1
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Anti-Müllerian hormone (AMH) autocrine signaling promotes survival and proliferation of ovarian cancer cells

Maëva Chauvin , Véronique Garambois , Pierre-Emmanuel Colombo , Myriam Chentouf , Laurent Gros , et al.
Scientific Reports, 2021, 11, pp.2231. ⟨10.1038/s41598-021-81819-y⟩
Article dans une revue hal-03131997v1
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Anti-cathepsin D immunotherapy triggers both innate and adaptive anti-tumour immunity in breast cancer

Timothée David , Aude Mallavialle , Julien Faget , Lindsay B Alcaraz , Marion Lapierre , et al.
British Journal of Pharmacology, 2023, ⟨10.1111/bph.16291⟩
Article dans une revue hal-04295033v1
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CD4 ligation excludes the Carma1-Bcl10-MALT1 complex from GM1-positive membrane rafts in CD3/CD28 activated T cells.

Maxime Rigo , Myriam Chentouf , André Pèlegrin , Thierry Chardès
Cellular Immunology, 2011, 270 (1), pp.40-6. ⟨10.1016/j.cellimm.2011.03.025⟩
Article dans une revue inserm-00588709v1
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Cellular and humoral recognition of Toxoplasma gondii P30 antigen and its cleavage fragments

Velge-Roussel F , Chardès T , Mevelec P , Bout D
Annales de Recherches Vétérinaires, 1992, 23 (3), pp.291-292
Article dans une revue hal-00902080v1
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HER3 as biomarker and therapeutic target in pancreatic cancer: new insights in pertuzumab therapy in preclinical models

Gaëlle Thomas , Thierry Chardès , Nadège Gaborit , Caroline Mollevi , Wilhem Leconet , et al.
Oncotarget, 2014, 5 (16), pp.7138-7148. ⟨10.18632/oncotarget.2231⟩
Article dans une revue hal-02387994v2