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2003: Brevet de Technicien Supérieur - Biochimiste (Académie de Lille)

2008: MASTER - Biochimie Structurale, Protéomique et Métabolomique (Académie de Toulouse)

2008/2009: Institut de Pharmacologie et de Biologie Structurale CNRS/UMR5089 (Toulouse) - Laboratoire de Protéomique et Spectrométrie de Masse des Biomolécules.

2009/2012: Laboratoire de Recherche en Sciences Végétales CNRS/UMR5546 (Castanet-Tolosan) - Equipe Protéines Pariétales et Développement.

2011/2015: Centre de Recherche en Cancérologie de Toulouse INSERM/U1037 (Toulouse) - Equipe Signalisation PI3K et Contrôle Traductionnel dans les Tumeurs Pancréatiques et Hypophysaires.

2015-2021: Institut Pasteur (Paris) - Unité de Technologie et de Service Spectrométrie de Masse pour la Biologie (UTechS MSBio)

Journal articles20 documents

  • Anna Griego, Thibaut Douché, Quentin Giai Gianetto, Mariette Matondo, Giulia Manina. RNase E and HupB dynamics foster mycobacterial cell homeostasis and fitness. iScience, Elsevier, 2022, 25 (5), pp.104233. ⟨10.1016/j.isci.2022.104233⟩. ⟨pasteur-03693876⟩
  • Transito Garcia-Garcia, Sandrine Poncet, Elodie Cuenot, Thibaut Douché, Quentin Giai Gianetto, et al.. Ser/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile. mBio, American Society for Microbiology, 2021, 12 (3), pp.e00519-21. ⟨10.1128/mBio.00519-21⟩. ⟨pasteur-03243540⟩
  • yanouk Epelboin, Lanjiao Wang, Quentin Giai Gianetto, Valérie Choumet, Pascal Gaborit, et al.. CYP450 core involvement in multiple resistance strains of Aedes aegypti from French Guiana highlighted by proteomics, molecular and biochemical studies. PLoS ONE, Public Library of Science, 2021, 16 (1), pp.e0243992. ⟨10.1371/journal.pone.0243992⟩. ⟨pasteur-03184205⟩
  • Alice Meignié, Chantal Combredet, Marc Santolini, István Kovács, Thibaut Douché, et al.. Proteomic Analysis Uncovers Measles Virus Protein C Interaction With p65–iASPP Protein Complex. Molecular and Cellular Proteomics, American Society for Biochemistry and Molecular Biology, 2021, 20, pp.100049. ⟨10.1016/j.mcpro.2021.100049⟩. ⟨pasteur-03184181⟩
  • Cristina Chiva, Teresa Mendes Maia, Christian Panse, Karel Stejskal, Thibaut Douché, et al.. Quality standards in proteomics research facilities: Common standards and quality procedures are essential for proteomics facilities and their users. EMBO Reports, EMBO Press, 2021, 22 (6), pp.e52626. ⟨10.15252/embr.202152626⟩. ⟨pasteur-03258884⟩
  • Alejandro Tejada Arranz, Rute G Matos, yves Quentin, Maxime Bouilloux-Lafont, Eloïse Galtier, et al.. RNase R is associated in a functional complex with the RhpA DEAD-box RNA helicase in Helicobacter pylori. Nucleic Acids Research, Oxford University Press, 2021, 49 (9), pp.5249-5264. ⟨10.1093/nar/gkab283⟩. ⟨pasteur-03242387⟩
  • Rémi Samain, Alexia Brunel, Thibaut Douché, Marjorie Fanjul, Stéphanie Cassant-Sourdy, et al.. Pharmacologic Normalization of Pancreatic Cancer-Associated Fibroblast Secretome Impairs Prometastatic Cross-Talk With Macrophages. Cellular and Molecular Gastroenterology and Hepatology, Philadelphia, PA : American Gastroenterological Association, [2015]-, 2021, 11 (5), pp.1405-1436. ⟨10.1016/j.jcmgh.2021.01.008⟩. ⟨pasteur-03252986⟩
  • Thibaut Douché, Benoît Valot, Thierry Balliau, Hélène San Clemente, Michel Zivy, et al.. Cell wall proteomic datasets of stems and leaves of Brachypodium distachyon. Data in Brief, Elsevier, 2021, 35, pp.1-4. ⟨10.1016/j.dib.2021.106818⟩. ⟨hal-03259235⟩
  • Cyril Addi, Adrien Presle, Stéphane Frémont, Frédérique Cuvelier, Murielle Rocancourt, et al.. The Flemmingsome reveals an ESCRT-to-membrane coupling via ALIX/syntenin/syndecan-4 required for completion of cytokinesis. Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.1941. ⟨10.1038/s41467-020-15205-z⟩. ⟨pasteur-02557366⟩
  • Darragh P. O'Brien, Alexis Voegele, Dorothee Raoux-Barbot, Marilyne Davi, Sara Cannella, et al.. Disorder-To-Order Transitions and Post-Translational Acylation Control the Folding and Activity of the Bordetella Pertussis CyaA Toxin. Biophysical Journal, Biophysical Society, 2020, 118 (3), pp.197A--197A. ⟨hal-02516165⟩
  • Elodie Cuenot, Transito Garcia-Garcia, Thibaut Douche, Olivier Gorgette, Pascal Courtin, et al.. The Ser/Thr kinase PrkC participates in cell wall homeostasis and antimicrobial resistance in Clostridium difficile. Infection and Immunity, American Society for Microbiology, 2019, 87 (8), pp.e00005-19. ⟨10.1128/IAI.00005-19⟩. ⟨pasteur-02164685⟩
  • Alexis Voegele, Mirko Sadi, Dorothée Raoux-Barbot, Thibaut Douche, Mariette Matondo, et al.. The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro. Toxins, MDPI, 2019, Special Issue RTX Toxins, 11 (2), pp.111. ⟨10.3390/toxins11020111⟩. ⟨pasteur-02329482⟩
  • Carolina Alves Feliciano, Thibaut Douche, Quentin Giai Gianetto, Mariette I Matondo, Isabelle Martin-Verstraete, et al.. CotL, a new morphogenetic spore coat protein of Clostridium difficile. Environmental Microbiology, Society for Applied Microbiology and Wiley-Blackwell, 2019, 21 (3), pp.984-1003. ⟨10.1111/1462-2920.14505⟩. ⟨pasteur-02331056⟩
  • Darragh O'Brien, Sara E Cannella, Alexis Voegele, Dorothée Raoux-Barbot, Marilyne Davi, et al.. Post-translational acylation controls the folding and functions of the CyaA RTX toxin. FASEB Journal, Federation of American Society of Experimental Biology, 2019, 33 (9), pp.10065-10076. ⟨10.1096/fj.201802442RR⟩. ⟨pasteur-02330713⟩
  • Celia Cintas, Thibaut Douche, Nicole Therville, Silvia Arcucci, Fernanda Ramos-Delgado, et al.. Signal-Targeted Therapies and Resistance Mechanisms in Pancreatic Cancer: Future Developments Reside in Proteomics. Cancers, MDPI, 2018, 10 (6), pp.174. ⟨10.3390/cancers10060174⟩. ⟨hal-02500132⟩
  • Magali Lago, Véronique Monteil, Thibaut Douche, Julien Guglielmini, Alexis Criscuolo, et al.. Proteome remodelling by the stress sigma factor RpoS/σS in Salmonella: identification of small proteins and evidence for post-transcriptional regulation. Scientific Reports, Nature Publishing Group, 2017, 7, pp.2127. ⟨10.1038/s41598-017-02362-3⟩. ⟨pasteur-01540240⟩
  • Valerie Bouchez, Thibaut Douche, Mélody Dazas, Sophie Delaplane, Mariette Matondo, et al.. Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates. Toxins, MDPI, 2017, 9 (10), pp.304. ⟨10.3390/toxins9100304⟩. ⟨pasteur-02573143⟩
  • Maria Juliana Calderan-Rodrigues, Elisabeth Jamet, Thibaut Douché, Maria Beatriz Rodrigues Bonassi, Thaís Regiani Cataldi, et al.. Cell wall proteome of sugarcane stems: comparison of a destructive and a non-destructive extraction method showed differences in glycoside hydrolases and peroxidases. BMC Plant Biology, 2016, 16 (1), pp.14. ⟨10.1186/s12870-015-0677-0⟩. ⟨hal-03259237⟩
  • Thibaut Douche, Hélène San Clemente, Vincent Burlat, David Roujol, Benoit B. Valot, et al.. Brachypodium distachyon as a model plant toward improved biofuel crops: search for secreted proteins involved in biogenesis and disassembly of cell wall polymers. Proteomics, Wiley-VCH Verlag, 2013, 13 (16), pp.2438-2454. ⟨10.1002/pmic.201200507⟩. ⟨hal-02647765⟩
  • Laurent Henry, Thierry Lavabre-Bertrand, Thibaut Douche, Sandrine Uttenweiler-Joseph, Pascale Fabbro-Peray, et al.. Diagnostic value and prognostic significance of plasmatic proteasome level in patients with melanoma. Experimental Dermatology, Wiley, 2010, 19 (12), pp.1054-1059. ⟨10.1111/j.1600-0625.2010.01151.x⟩. ⟨hal-02503539⟩

Preprints, Working Papers, ...3 documents

  • C Cintas, T Douche, Z Dantes, E Mouton-Barbosa, Mp Bousquet, et al.. Phosphoproteomics identifies PI3K inhibitor-selective adaptive responses in pancreatic cancer cell therapy and resistance: Mapping PI3K inhibitor-dependent phosphoproteome. 2021. ⟨hal-03223423⟩
  • Darragh P O'Brien, Sara E Cannella, Alexis Voegele, Dorothée Raoux-Barbot, Maryline Davi, et al.. Post-translational acylation controls the folding and functions of the CyaA RTX toxin. 2021. ⟨pasteur-03221015⟩
  • Laura Piel, K. Shanmugha Rajan, Giovanni Bussotti, Hugo Varet, Rachel Legendre, et al.. Post-transcriptional regulation of Leishmania fitness gain. 2021. ⟨pasteur-03210825⟩