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Monomeric Nucleoprotein of Influenza A Virus

Sylvie Chenavas , Leandro F. Estrozi , Anny Slama-Schwok , Bernard Delmas , Carmelo Di Primo , et al.
PLoS Pathogens, 2013, 9 (3), ⟨10.1371/journal.ppat.1003275⟩
Article dans une revue hal-01666129v1
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The structure of the nucleoprotein of Influenza D shows that all Orthomyxoviridae nucleoproteins have a similar NPCORE, with or without a NPTAIL for nuclear transport

Amélie Donchet , Justine Oliva , Alice Labaronne , Laura Tengo , Myriam Miloudi , et al.
Scientific Reports, 2019, 9, pp.600. ⟨10.1038/s41598-018-37306-y⟩
Article dans une revue hal-01997471v2

Structural analysis of the complex between influenza B nucleoprotein and human importin-α

Alice Labaronne , Sigrid Milles , Amélie Donchet , Malene Ringkjøbing Jensen , Martin Blackledge , et al.
Scientific Reports, 2017, 7 (1), pp.17164. ⟨10.1038/s41598-017-17458-z⟩
Article dans une revue hal-01664797v1

Influenza virus nucleoprotein: structure, RNA binding, oligomerization and antiviral drug target

Sylvie Chenavas , Thibaut Crépin , Bernard Delmas , Rob W H Ruigrok , Anny Slama-Schwok
Future Microbiology, 2013, 8 (12), pp.1537 - 1545. ⟨10.2217/fmb.13.128⟩
Article dans une revue hal-01666096v1

Mammalian translation elongation factor eEF1A2: X-ray structure and new features of GDP/GTP exchange mechanism in higher eukaryotes

Thibaut Crepin , Vyacheslav Shalak , Anna Yaremchuk , Dmytro Vlasenko , Andrew Mccarthy , et al.
Nucleic Acids Research, 2014, 42 (20), pp.12939-12948. ⟨10.1093/nar/gku974⟩
Article dans une revue hal-01995922v1
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Differential Behaviours and Preferential Bindings of Influenza Nucleoproteins on Importins-α

Amélie Donchet , Emilie Vassal-Stermann , Francine Gérard , Rob W H Ruigrok , Thibaut Crépin
Viruses, 2020, 12 (8), pp.834. ⟨10.3390/v12080834⟩
Article dans une revue hal-02912888v1

Binding of RNA by the Nucleoproteins of Influenza Viruses A and B

Alice Labaronne , Christopher Swale , Alexandre Monod , Guy Schoehn , Thibaut Crépin , et al.
Viruses, 2016, 8 (9), pp.247. ⟨10.3390/v8090247⟩
Article dans une revue hal-01366655v1

Polyproteins in structural biology.

Thibaut Crépin , Christopher Swale , Alexandre Monod , Frederic Garzoni , Maxime Chaillet , et al.
Current Opinion in Structural Biology, 2015, 32, pp.139-46
Article dans une revue hal-01241235v1
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Influenza viruses and coronaviruses: Knowns, unknowns, and common research challenges

Olivier Terrier , Mustapha Si-Tahar , Mariette Ducatez , Christophe Chevalier , Andrés Pizzorno , et al.
PLoS Pathogens, 2021, 17 (12), pp.e1010106. ⟨10.1371/journal.ppat.1010106⟩
Article dans une revue hal-03518306v1
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Sendai Virus and a Unified Model of Mononegavirus RNA Synthesis

Daniel Kolakofsky , Philippe Le Mercier , Machiko Nishio , Martin Blackledge , Thibaut Crepin , et al.
Viruses, 2021, 13 (12), pp.2466. ⟨10.3390/v13122466⟩
Article dans une revue hal-03518294v1

Editorial overview: virus structure and function.

Wah Chiu , Thibaut Crépin , Rob W H Ruigrok
Current Opinion in Virology, 2014, 5, pp.viii-ix
Article dans une revue hal-01132331v1

Structural characterization of recombinant IAV polymerase reveals a stable complex between viral PA-PB1 heterodimer and host RanBP5.

Christopher Swale , Alexandre Monod , Laura Tengo , Alice Labaronne , Frédéric Garzoni , et al.
Scientific Reports, 2016, 6, pp.24727. ⟨10.1038/srep24727⟩
Article dans une revue hal-01342969v1

Structure of the tetramerization domain of measles virus phosphoprotein.

Guillaume Communie , Thibaut Crépin , Damien Maurin , Malene Ringkjøbing Jensen , Martin Blackledge , et al.
Journal of Virology, 2013, 87 (12), pp.7166-9. ⟨10.1128/JVI.00487-13⟩
Article dans une revue hal-01321590v1
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Cryo-EM structure of influenza helical nucleocapsid reveals NP-NP and NP-RNA interactions as a model for the genome encapsidation

Florian Chenavier , Leandro Estrozi , Jean-Marie Teulon , Eleftherios Zarkadas , Lily-Lorette Freslon , et al.
Science Advances , 2023, 9 (50), pp.eadj9974. ⟨10.1126/sciadv.adj9974⟩
Article dans une revue hal-04352762v1
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Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein

Antoine Guillon , Deborah Bréa-Diakite , Adeline Cezard , Alan Wacquiez , Thomas Baranek , et al.
EMBO Journal, 2022, 41 (12), pp.e108306. ⟨10.15252/embj.2021108306⟩
Article dans une revue hal-03687124v2

Learning from structure-based drug design and new antivirals targeting the ribonucleoprotein complex for the treatment of influenza

Alexandre Monod , Christopher Swale , Bogdan Tarus , Alice Tissot , Bernard B. Delmas , et al.
Expert Opinion on Drug Discovery, 2015, 10 (4), pp.345-371. ⟨10.1517/17460441.2015.1019859⟩
Article dans une revue hal-02639384v1
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Biologie structurale de complexes protéine:ARN

Thibaut Crépin
Biologie structurale [q-bio.BM]. Université Grenoble Alpes, 2017
HDR tel-02269002v1

Comparative structural and functional analysis of orthomyxovirus polymerase cap-snatching domains.

Delphine Guilligay , Jan Kadlec , Thibaut Crépin , Thomas Lunardi , Denis Bouvier , et al.
PLoS ONE, 2013, 9 (1), pp.e84973
Article dans une revue hal-01132338v1
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Destabilization of the human RED–SMU1 splicing complex as a basis for host-directed antiinfluenza strategy

Usama Ashraf , Laura Tengo , Laurent Le Corre , Guillaume Fournier , Patricia Busca , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (22), pp.10968-10977. ⟨10.1073/pnas.1901214116⟩
Article dans une revue hal-02160991v1

Structure and function of the C-terminal domain of methionyl-tRNA synthetase.

Thibaut Crepin , Emmanuelle Schmitt , Sylvain Blanquet , Yves Mechulam
Biochemistry, 2002, 41 (43), pp.13003-11. ⟨10.1021/bi026343m⟩
Article dans une revue istex hal-00770920v1

Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.

Thibaut Crepin , Emmanuelle Schmitt , Yves Mechulam , P.B. Sampson , M.D. Vaughan , et al.
Journal of Molecular Biology, 2003, 332 (1), pp.59-72. ⟨10.1016/S0022-2836(03)00917-3⟩
Article dans une revue istex hal-00770917v1

Methionyl-tRNA Synthetases

Sylvain Blanquet , Thibaut Crepin , Yves Mechulam , Emmanuelle Schmitt
Michael Ibba, Christopher Francklyn, Stephen Cusack. The Aminoacyl-tRNA Synthetases, Landes Biosciences, Chapter 6, 2005, 978-1-58706-189-9
Chapitre d'ouvrage hal-00771997v1

Three-dimensional structure of methionyl-tRNA synthetase from Pyrococcus abyssi.

Thibaut Crepin , Emmanuelle Schmitt , Sylvain Blanquet , Yves Mechulam
Biochemistry, 2004, 43 (9), pp.2635-44. ⟨10.1021/bi0356247⟩
Article dans une revue istex hal-00770713v1
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X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking

Christopher Swale , Bruno da Costa , Laura Sedano , Frederic Garzoni , Andrew Mccarthy , et al.
Journal of Molecular Biology, 2020, 432 (10), pp.3353-3359. ⟨10.1016/j.jmb.2020.03.021⟩
Article dans une revue hal-02555361v1

Capsid proteins of enveloped viruses as antiviral drug targets.

Klaus Klumpp , Thibaut Crépin
Current Opinion in Virology, 2014, 5, pp.63-71
Article dans une revue hal-01158408v1

In Vitro/In Vivo Production of tRNA for X-Ray Studies

Clément Dégut , Alexandre Monod , Franck Brachet , Thibaut Crépin , Carine Tisné
Methods in Molecular Biology, 2016, 1320, pp.37-57. ⟨10.1007/978-1-4939-2763-0_4⟩
Article dans une revue hal-01993848v1

Structural insight into cap-snatching and RNA synthesis by influenza polymerase.

Stefan Reich , Delphine Guilligay , Alexander Pflug , Hélène Malet , Imre Berger , et al.
Nature, 2014, 516 (7531), pp.361-6
Article dans une revue hal-01132328v1
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Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing

Nicolas Tarbouriech , Florian Chenavier , Junna Kawasaki , Kamel Bachiri , Jean-Marie Bourhis , et al.
Viruses, 2022, 14 (11), pp.2358. ⟨10.3390/v14112358⟩
Article dans une revue hal-03834032v1