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Lipopolysaccharide Induces GFAT2 Expression to Promote O -Linked β- N -Acetylglucosaminylation and Attenuate Inflammation in Macrophages

Hasanain Al-Mukh , Léa Baudoin , Abdelouhab Bouaboud , José-Luis Sanchez- Salgado , Nabih Maraqa , et al.
Journal of Immunology, 2020, 205 (9), pp.2499-2510. ⟨10.4049/jimmunol.2000345⟩
Article dans une revue hal-03026534v1

Protein O-GlcNAcylation and the regulation of energy homeostasis: lessons from knock-out mouse models

Tarik Issad , Hasanain Al-Mukh , Abdelouhab Bouaboud , Patrick Pagesy
Journal of Biomedical Science, 2022, 29 (1), pp.64. ⟨10.1186/s12929-022-00851-w⟩
Article dans une revue hal-03854167v1

Tax : une oncoprotéine virale qui aime les CREB sucrés !

Claudine Pique , Tarik Issad
Médecine/Sciences, 2018, 34 (2), pp.120-122. ⟨10.1051/medsci/20183402006⟩
Article dans une revue hal-02410503v1
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O-GlcNAc transferase acts as a critical nutritional node for the control of liver homeostasis

Paula Ortega-Prieto , Lucia Parlati , Fadila Benhamed , Marion Regnier , Isadora Cavalcante , et al.
JHEP Reports Innovation in Hepatology, 2023, pp.100878. ⟨10.1016/j.jhepr.2023.100878⟩
Article dans une revue hal-04195305v1
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Protein O-GlcNAcylation and the regulation of energy homeostasis: lessons from knock-out mouse models

Tarik Issad , Hasanain Al-Mukh , Abdelouhab Bouaboud , Patrick Pagesy
Journal of Biomedical Science, 2022, 29, ⟨10.1186/s12929-022-00851-w⟩
Article dans une revue hal-03874049v1

Human immortalized brown adipocytes express functional bêta3-adrenoceptor coupled to lipolysis

V. Zilberfarb , F. Pietri-Rouxel , Ralf Jockers , Simon Krief , Claude Delouis , et al.
Journal of Cell Science, 1997, 110, pp.801-807
Article dans une revue hal-02686235v1
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Increased O-GlcNAcylation promotes IGF-1 receptor/PhosphatidyI Inositol-3 kinase/Akt pathway in cervical cancer cells

Victoria Jiménez-Castillo , Daniela Illescas-Barbosa , Edgar Zenteno , Beatriz Xóchitl Ávila-Curiel , Maria Cristina Castañeda-Patlán , et al.
Scientific Reports, 2022, 12 (1), pp.4464. ⟨10.1038/s41598-022-08445-0⟩
Article dans une revue hal-03874673v1
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30 Years Old: O-GlcNAc Reaches the Age of Reason - Regulation of Cell Signaling and Metabolism by O-GlcNAcylation

Tony Lefebvre , Tarik Issad
Frontiers in Endocrinology, 2015, 6, pp.17. ⟨10.3389/fendo.2015.00017⟩
Article dans une revue inserm-01154355v1

Increased OGA Expression and Activity in Leukocytes from Patients with Diabetes: Correlation with Inflammation Markers

Patrick Pagesy , Caroline Tachet , Ali Mostefa-Kara , Etienne Larger , Tarik Issad
Experimental and Clinical Endocrinology and Diabetes, 2019, 127 (08), pp.517-523. ⟨10.1055/a-0596-7337⟩
Article dans une revue hal-02415614v1
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O-GlcNAcylation and inflammation: a vast territory to explore

Léa Baudoin , Tarik Issad
Frontiers in Endocrinology, 2015, ⟨10.3389/fendo.2014.00235⟩
Article dans une revue inserm-01103384v1

Dual regulation of TxNIP by ChREBP and FoxO1 in liver

Benedicte Noblet , Fadila Benhamed , Insug O-Sullivan , Wenwei Zhang , Gaëlle Filhoulaud , et al.
iScience, 2021, 24 (3), pp.102218. ⟨10.1016/j.isci.2021.102218⟩
Article dans une revue hal-03963490v1
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O-GlcNacylation Links TxNIP to Inflammasome Activation in Pancreatic β Cells

Gaelle Filhoulaud , Fadila Benhamed , Patrick Pagesy , Caroline Bonner , Yann Fardini , et al.
Frontiers in Endocrinology, 2019, 10, pp.291. ⟨10.3389/fendo.2019.00291⟩
Article dans une revue hal-02196741v1
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O-GlcNAcylation des protéines, homéostasie énergétique et maladies métaboliques

Tarik Issad , Hasanain Al-Mukh , Abdelouhab Bouaboud , Patrick Pagesy
Médecine des Maladies Métaboliques, 2022, 16 (4), pp.343-350. ⟨10.1016/j.mmm.2022.02.005⟩
Article dans une revue hal-03854291v1

Editorial: O-GlcNAcylation: Expanding the Frontiers

Tarik Issad , Tony Lefebvre
Frontiers in Endocrinology, 2019, 10, ⟨10.3389/fendo.2019.00867⟩
Article dans une revue hal-02415629v1

Regulatory O-GlcNAcylation sites on FoxO1 are yet to be identified

Yann Fardini , Yobana Perez-Cervera , Luc Camoin , Patrick Pagesy , Tony Lefebvre , et al.
Biochemical and biophysical research communications, 2015, Biochemical and biophysical research communications, 462 (2), pp.151-158. ⟨10.1016/j.bbrc.2015.04.114⟩
Article dans une revue hal-03285064v1
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Protein O ‐GlcNAcylation levels are regulated independently of dietary intake in a tissue and time‐specific manner during rat postnatal development

Thomas Dupas , Manon Denis , Justine Dontaine , Antoine Persello , Laurent Bultot , et al.
Acta Physiologica, 2021, ⟨10.1111/apha.13566⟩
Article dans une revue hal-03026470v1
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Tau deletion promotes brain insulin resistance

Elodie Marciniak , Antoine Leboucher , Emilie Caron , Tariq Ahmed , Anne Tailleux , et al.
Journal of Experimental Medicine, 2017, 214 (8), pp.2257 - 2269. ⟨10.1084/jem.20161731⟩
Article dans une revue inserm-01833342v1

Increased mitogen activated protein kinase expression and activity in white adipose tissue of ventromedial hypothalamus-lesioned rats

M. Combettes-Souverain , Luc Pénicaud , P. Ferre , T. Issad
Diabetologia, 1997, 40, pp.533-40
Article dans une revue hal-00408587v1

Increased O-GlcNAcylation promotes IGF-1 receptor/PhosphatidyI Inositol-3 kinase/Akt pathway in cervical cancer cells

Victoria Jiménez-Castillo , Daniela Illescas-Barbosa , Edgar Zenteno , Beatriz Xóchitl Ávila-Curiel , Maria Cristina Castañeda-Patlán , et al.
Scientific Reports, 2022, 12 (1), pp.4464. ⟨10.1038/s41598-022-08445-0⟩
Article dans une revue hal-03874073v1
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Dual regulation of TxNIP by ChREBP and FoxO1 in liver

Bénédicte Noblet , Fadila Benhamed , Insug O-Sullivan , Wenwei Zhang , Gaelle Filhoulaud , et al.
iScience, 2021, 24 (3), pp.102218. ⟨10.1016/j.isci.2021.102218⟩
Article dans une revue hal-03176271v1

La recherche sur le cancer - Un champ privilégié pour penser les rapports entre hasard, réductionnisme et holisme

Anna C. Zielinska , Tarik Issad
Médecine/Sciences, 2014, 30 (6-7), pp.675--678. ⟨10.1051/medsci/20143006019⟩
Article dans une revue hal-02925074v1

O-GlcNAcylation of FoxO1 in pancreatic β cells promotes Akt inhibition through an IGFBP1-mediated autocrine mechanism

Yann Fardini , Elodie A.Y. Masson , Ouassila Boudah , Rania Ben Jouira , Camille Cosson , et al.
FASEB Journal, 2014, 28 (2), pp.1010-1021. ⟨10.1096/fj.13-238378⟩
Article dans une revue hal-01123110v1
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Are Dynamic Mechanistic Explanations Still Mechanistic?

Tarik Issad , Christophe Malaterre
Pierre-Alain Braillard ; Christophe Malaterre. EXPLANATION IN BIOLOGY: AN ENQUIRY INTO THE DIVERSITY OF EXPLANATORY PATTERNS IN THE LIFE SCIENCES, 11, Springer, pp.Pages: 265-292, 2015, History Philosophy and Theory of the Life Sciences, ⟨10.1007/978-94-017-9822-8_12⟩
Chapitre d'ouvrage hal-02196795v1

Neuroinflammation induced by amyloid β25–35 modifies mucin-type O -glycosylation in the rat's hippocampus

Ivan Ramos-Martinez , Pamela Martínez-Loustalot , Liliana Lozano , Tarik Issad , Daniel Limón , et al.
Neuropeptides, 2018, 67, pp.56-62. ⟨10.1016/j.npep.2017.11.008⟩
Article dans une revue hal-02410507v1
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Croissance et puberté : évolutions séculaires, facteurs environnementaux et génétiques

Serge Amselem , Jean-Claude Carel , Nicolas de Roux , Tarik Issad , Stéfania Maccari , et al.
[Rapport de recherche] Institut national de la santé et de la recherche médicale(INSERM). 2007, 176 p., cartes, graphiques, références bibliographiques disséminées
Rapport hal-01570647v1
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Development of a human breast-cancer derived cell line stably expressing a bioluminescence resonance energy transfer (BRET)-based phosphatidyl inositol-3 phosphate (PIP3) biosensor.

Mei-Shiue Kuo , Johanna Auriau , Cécile Pierre-Eugène , Tarik Issad
PLoS ONE, 2014, 9 (3), pp.e92737. ⟨10.1371/journal.pone.0092737⟩
Article dans une revue inserm-01067930v1
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Changes in energy metabolism during the suckling and weaning period in the newborn

P. Ferré , J.-F. Decaux , T. Issad , J. Girard
Reproduction Nutrition Développement, 1986, 26 (2B), pp.619-631
Article dans une revue hal-00898473v1
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L’ontophylogenèse : une extension du darwininisme à l’intérieur de l’organisme

Tarik Issad
2019
Pré-publication, Document de travail hal-02410516v1
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O-GlcNAcylation-Inducing Treatments Inhibit Estrogen Receptor α Expression and Confer Resistance to 4-OH-Tamoxifen in Human Breast Cancer-Derived MCF-7 Cells.

Shahzina Kanwal , Yann Fardini , Patrick Pagesy , Thierry N'Tumba-Byn , Cécile Pierre-Eugène , et al.
PLoS ONE, 2013, 8 (7), pp.e69150. ⟨10.1371/journal.pone.0069150⟩
Article dans une revue hal-00866032v1

Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice

Anne Fougerat , Xuefang Pan , Victoria Smutova , Nikolaus Heveker , Christopher Cairo , et al.
Molecular metabolism, 2018, 12, pp.76-88. ⟨10.1016/j.molmet.2018.03.017⟩
Article dans une revue hal-02410501v1