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Novel benzimidazole-based pseudo-irreversible butyrylcholinesterase inhibitors with neuroprotective activity in an Alzheimer's disease mouse model

Philipp Spatz , Thomas Zimmermann , Sophie Steinmüller , Julian Hofmann , Tangui Maurice , et al.
RSC Medicinal Chemistry, 2022, 13 (8), pp.944-954. ⟨10.1039/d2md00087c⟩
Article dans une revue hal-04267435v1

An Intranasal Formulation of Erythropoietin (Neuro-EPO) Prevents Memory Deficits and Amyloid Toxicity in the APPSwe Transgenic Mouse Model of Alzheimer’s Disease

Yamila Rodríguez Cruz , Manon Strehaiano , Teresita Rodríguez Obaya , Julío César García Rodríguez , Tangui Tm Maurice
Journal of Alzheimer's Disease, 2016, 55 (1), pp.231 - 248. ⟨10.3233/JAD-160500⟩
Article dans une revue hal-01922572v1

Role of σ1 Receptors in Learning and Memory and Alzheimer’s Disease-Type Dementia

Tangui Maurice , Nino Goguadze
Advances in Experimental Medicine and Biology, 2017, 964, pp.213-233. ⟨10.1007/978-3-319-50174-1_15⟩
Article dans une revue hal-01998707v1

Increased Amyloid-β Peptide-Induced Memory Deficits in Phospholipid Transfer Protein (PLTP) Gene Knockout Mice

Catherine Desrumaux , Amandine Pisoni , Johann Meunier , Valérie Deckert , Anne Athias , et al.
Neuropsychopharmacology, 2013, 38 (5), pp.817-825. ⟨10.1038/npp.2012.247⟩
Article dans une revue hal-04199812v1
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Masculinised Behaviour of XY Females in a Mammal with Naturally Occurring Sex Reversal

Paul Saunders , Thomas Franco , Camille Sottas , Tangui Tm Maurice , Guila Ganem , et al.
Scientific Reports, 2016, 6 (1), ⟨10.1038/srep22881⟩
Article dans une revue hal-01922577v1

Neuroactive steroids modulate HPA axis activity and cerebral brain-derived neurotrophic factor (BDNF) protein levels in adult male rats

Gaëlle Naert , Tangui Tm Maurice , Lucia Tapia-Arancibia , Laurent Givalois
Psychoneuroendocrinology, 2007, 32 (8-10), pp.1062 - 1078. ⟨10.1016/j.psyneuen.2007.09.002⟩
Article dans une revue istex hal-01923546v1

The 3β-hydroxysteroid dehydrogenase inhibitor trilostane shows antidepressant properties in mice

Julie Espallergues , Laurent Givalois , Jamal Temsamani , Claude Laruelle , Tangui Tm Maurice
Psychoneuroendocrinology, 2009, 34 (5), pp.644 - 659. ⟨10.1016/j.psyneuen.2008.11.003⟩
Article dans une revue istex hal-01923545v1

Hyposensitivity to the amnesic effects of scopolamine or amyloid beta25-35 peptide in heterozygous acetylcholinesterase knockout (AchE+/-) mice

Arnaud Chatonnet , Julie Espallergues , L. Galvan , Laurence Lepourry , Béatrice Bonafos , et al.
9. International Meeting on Cholinesterases, May 2007, Suzhou, China. 1 p
Communication dans un congrès hal-02823056v1

Oxidative stress, inflammation, and autophagic stress as the key mechanisms of premature age-related hearing loss in SAMP8 mouse cochlea

Julien Menardo , Yong Tang , Sabine Ladrech , François Casas , Christophe Michel , et al.
Antioxidants and Redox Signaling, 2012, 16 (3), pp.263-274. ⟨10.1089/ars.2011.4037⟩
Article dans une revue hal-02650777v1
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Sigma-1 receptor is a key genetic modulator in amyotrophic lateral sclerosis

Simon Couly , Bilal Khalil , Véronique Viguier , Julien Roussel , Tangui Tm Maurice , et al.
Human Molecular Genetics, 2020, 29 (4), pp.529-540. ⟨10.1093/hmg/ddz267⟩
Article dans une revue hal-02360092v1

Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition in Vitro and Enable Restoration of Cognition in an Alzheimer’s Disease Mouse Model upon Irradiation

Matthias Scheiner , Alexandra Sink , Matthias Hoffmann , Cassandre Vrigneau , Erik Endres , et al.
Journal of the American Chemical Society, 2022, 144 (7), pp.3279-3284. ⟨10.1021/jacs.1c13492⟩
Article dans une revue hal-04267429v1
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Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy

Ilya Chumakov , Serguei Nabirotchkin , Nathalie Cholet , Aude Milet , Aurélie Boucard , et al.
Scientific Reports, 2015, 5 (1), ⟨10.1038/srep07608⟩
Article dans une revue hal-01922611v1
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Sigma-1 Receptor Is Critical for Mitochondrial Activity and Unfolded Protein Response in Larval Zebrafish

Lucie Crouzier , Morgane Denus , Elodie Richard , Amarande Tavernier , Camille Diez , et al.
International Journal of Molecular Sciences, 2021, 22 (20), pp.11049. ⟨10.3390/ijms222011049⟩
Article dans une revue inserm-03845627v1

Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ1) receptor ligands with potent anti-amnesic effect

Francesca Abatematteo , Philip Mosier , Mauro Niso , Leonardo Brunetti , Francesco Berardi , et al.
European Journal of Medicinal Chemistry, 2022, 228, pp.114038. ⟨10.1016/j.ejmech.2021.114038⟩
Article dans une revue inserm-03845632v1
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Loss of Pde6a Induces Rod Outer Segment Shrinkage and Visual Alterations in pde6aQ70X Mutant Zebrafish, a Relevant Model of Retinal Dystrophy

Lucie Crouzier , Camille Diez , Elodie Richard , Nicolas Cubedo , Clément Barbereau , et al.
Frontiers in Cell and Developmental Biology, 2021, 9, ⟨10.3389/fcell.2021.675517⟩
Article dans une revue hal-03243690v1

Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models

Lucie Crouzier , Alberto Danese , Yuko Yasui , Elodie Richard , Jean-Charles Liévens , et al.
Science Translational Medicine, 2022, 14 (631), pp.eabh3763. ⟨10.1126/scitranslmed.abh3763⟩
Article dans une revue hal-03757649v1

At the Crossing of ER Stress and MAMs: A Key Role of Sigma-1 Receptor?

Benjamin Delprat , Lucie Crouzier , Tsung-Ping Su , Tangui Maurice
Adv Exp Med Biol, 1131, pp.699-718, 2020, ⟨10.1007/978-3-030-12457-1_28⟩
Chapitre d'ouvrage inserm-02380039v1

The effects of sigma (σ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice

Maninder Malik , Claudia Rangel-Barajas , Nathalie Su , Chang Su , Meharvan Singh , et al.
British Journal of Pharmacology, 2015, 172 (10), pp.2519 - 2531. ⟨10.1111/bph.13076⟩
Article dans une revue hal-01922593v1

Learning performances and vulnerability to amyloid toxicity in acetylcholinesterase and butyrylcholinesterase knockout mice

Tangui Maurice , Manon Strehaiano , Nathalie Siméon , Christelle Bertrand , Arnaud Chatonnet
Journal of Neurochemistry, 2017, 142 (Aout), pp.197-197. ⟨10.1111/jnc.13925⟩
Article dans une revue hal-01604889v1
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Alzheimer's Disease Related Markers, Cellular Toxicity and Behavioral Deficits Induced Six Weeks after Oligomeric Amyloid-β Peptide Injection in Rats

Charleine Zussy , Anthony Brureau , Emeline Keller , Stéphane Marchal , Claire Blayo , et al.
PLoS ONE, 2013, 8 (1), ⟨10.1371/journal.pone.0053117⟩
Article dans une revue hal-01923527v1

Deficiency of G3BP1, the stress granules assembly factor, results in abnormal synaptic plasticity and calcium homeostasis in neurons.

Sophie Martin , Latifa Zekri , Alexandra Metz , Tangui Maurice , Karim Chebli , et al.
Journal of Neurochemistry, 2013, epub ahead of print. ⟨10.1111/jnc.12189⟩
Article dans une revue hal-00809186v1

The three-panel runway maze adapted to Microcebus murinus reveals age-related differences in memory and perseverance performances

Stephanie Trouche , Tangui Tm Maurice , Sylvie Rouland , Jean-Michel Verdier , Nadine Frances
Neurobiology of Learning and Memory, 2010, 94, pp.100-106. ⟨10.1016/j.nlm.2010.04.006⟩
Article dans une revue hal-00603380v1
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In Vivo Characterization of ARN14140, a Memantine/Galantamine-Based Multi-Target Compound for Alzheimer’s Disease

Angelo Reggiani , Elena Simoni , Roberta Caporaso , Johann Meunier , Emeline Keller , et al.
Scientific Reports, 2016, 6 (1), ⟨10.1038/srep33172⟩
Article dans une revue hal-01922573v1
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Neuroprotective effect of Neuro-EPO in neurodegenerative diseases: “Alea jacta est”

Ramón Rama , Fernando Garzón , Yamila Rodríguez-Cruz , Tangui Maurice , Julio-César García-Rodríguez
Neural Regeneration Research, 2019, 14 (9), pp.1519. ⟨10.4103/1673-5374.255968⟩
Article dans une revue hal-02979257v1
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Sigma-1 (σ1) receptor activity is necessary for physiological brain plasticity in mice

Lucie Crouzier , Simon Couly , Chloé Roques , Coralie Peter , Rislen Belkhiter , et al.
European Neuropsychopharmacology, 2020, ⟨10.1016/j.euroneuro.2020.08.010⟩
Article dans une revue hal-03020937v1

The pathomimetic oAβ25–35 model of Alzheimer's disease: potential for screening of new therapeutic agents

Geoffrey Canet , Charleine Zussy , Célia Hernandez , Tangui Maurice , Catherine Desrumaux , et al.
Pharmacology and Therapeutics, 2023, 245, pp.108398. ⟨10.1016/j.pharmthera.2023.108398⟩
Article dans une revue hal-04197679v1

Synthesis and Biological Evaluation of Flavonoid‐Cinnamic Acid Amide Hybrids with Distinct Activity against Neurodegeneration in Vitro and in Vivo

Julian Hofmann , Philipp Spatz , Rasmus Walther , Marcus Gutmann , Tangui Maurice , et al.
Chemistry - A European Journal, 2022, 28 (39), ⟨10.1002/chem.202200786⟩
Article dans une revue hal-04267404v1

Brain-derived neurotrophic factor and hypothalamic-pituitary-adrenal axis adaptation processes in a depressive-like state induced by chronic restraint stress

Gaëlle Naert , Guy Ixart , Tangui Tm Maurice , Lucia Tapia-Arancibia , Laurent Givalois
Molecular and Cellular Neuroscience, 2011, 46 (1), pp.55 - 66. ⟨10.1016/j.mcn.2010.08.006⟩
Article dans une revue istex hal-01923543v1

Neuroprotection by the synthetic neurosteroid enantiomers ent-PREGS and ent-DHEAS against Aβ25–35 peptide-induced toxicity in vitro and in vivo in mice

Fadia El Bitar , Johann Meunier , Vanessa Villard , Marion Alméras , Kathiresan Krishnan , et al.
Psychopharmacology, 2014, 231 (17), pp.3293-3312. ⟨10.1007/s00213-014-3435-3⟩
Article dans une revue hal-02007648v1

Preliminary phytochemical screening and protective effect of Erythrina Senegalensis in an in vivo mouse model of Alzheimer's disease

Marcellin Koffi Ahue , Janat A. Mamyrbekova Bekro , Tangui Maurice , David Virieux , Jean-Luc Pirat , et al.
Journal of Medical Pharmaceutical And Allied Sciences, 2017, March_2017, pp.630-644
Article dans une revue hal-01997561v1