Sylvie RADIX

Documents

Présentation

Publications

	P143 Clinical observation leads to the synthesis of BG185, a new antistaphylococcal compound B. Gioia , C. Commun , A. Arnaud , Serge Michalet , S. Radix Journal of Cystic Fibrosis, 2020, 19, pp.S96. ⟨10.1016/S1569-1993(20)30478-1⟩ Article dans une revue hal-03160128v1
	Solvent- and metal-free hydroboration of alkynes under microwave irradiation Bruna Gioia , Alexandre Arnaud , Sylvie Radix , Nadia Walchshofer , Anne Doleans-Jordheim Tetrahedron Letters, 2020, ⟨10.1016/j.tetlet.2020.151596⟩ Article dans une revue hal-02443839v1
	Synthesis and biological evaluation of new dipicolylamine zinc chelators as metallo-β-lactamase inhibitors Anthony Prandina , Sylvie Radix , Marc Le Borgne , Lars Petter Jordheim , Zineb Bousfiha Tetrahedron, 2019, 75 (11), pp.1525-1540. ⟨10.1016/j.tet.2019.02.004⟩ Article dans une revue hal-02054167v1
	Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors Geir Kildahl-Andersen , Christian Schnaars , Anthony Prandina , Sylvie Radix , Marc Le Borgne MedChemComm, inPress, 10 (4), pp.528-537. ⟨10.1039/C8MD00578H⟩ Article dans une revue hal-02077900v1
	Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles Anthony Prandina , Lars Herfindal , Sylvie Radix , Pal Rongved , Stein Døskeland Journal of Enzyme Inhibition and Medicinal Chemistry, 2018, 33 (1), pp.370 - 375. ⟨10.1080/14756366.2017.1421638⟩ Article dans une revue hal-01688994v1
	Synthesis and preclinical evaluation of TPA-based zinc chelators as metallo-β-lactamase inhibitors Christian Schnaars , Geir Kildahl-Andersen , Anthony Prandina , Roya Popal , Sylvie Large Radix ACS Infectious Diseases, 2018, ⟨10.1021/acsinfecdis.8b00137⟩ Article dans une revue hal-01844562v1
	N,N′-disubstituted cinnamamide derivatives potentiate ciprofloxacin activity against overexpressing NorA efflux pump Staphylococcus aureus 1199B strains Sylvie Radix , Anne Doléans Jordheim , Luc Rocheblave , Serge N'Digo , Anne-Laure Prignon European Journal of Medicinal Chemistry, 2018, 150, pp.900 - 907. ⟨10.1016/j.ejmech.2018.03.028⟩ Article dans une revue hal-01763023v1
	Unsymmetrical α,ω-end-functionalized oligo(cyclohexylidenes): efficient synthesis and conformational analysis Wael Zeinyeh , Sylvie Radix , Raphael Terreux , Julie-Anne Chemelle , Nadia Walchshofer Tetrahedron, 2016, 72 (27-28), pp.4032 - 4038. ⟨10.1016/j.tet.2016.05.040⟩ Article dans une revue hal-01800196v1
	Deoxycholic acid derivatives as inhibitors of P-glycoprotein-mediated multidrug efflux Luc Rocheblave , Marc Rolland De Ravel , Elodie Monniot , Jeremy Tavenard , Claude-Yves Cuilleron Steroids, 2016, 116 (1878-5867 (Electronic)), pp.5-12. ⟨10.1016/j.steroids.2016.09.017⟩ Article dans une revue hal-01800021v1
	Progesterone–adenine hybrids as bivalent inhibitors of P-glycoprotein-mediated multidrug efflux: Design, synthesis, characterization and biological evaluation Wael Zeinyeh , Zahia Mahiout , Sylvie Radix , Thierry Lomberget , Axel Dumoulin Steroids, 2012, 77 (12), pp.1177 - 1191. ⟨10.1016/j.steroids.2012.07.010⟩ Article dans une revue hal-01800194v1
	Synthesis and modulation properties of imidazo[4,5-b]pyridin-7-one and indazole-4,7-dione derivatives towards the Cryptosporidium parvum CpABC3 transporter Waël Zeinyeh , Hexue Xia , Philippe Lawton , Sylvie Radix , Christelle Marminon European Journal of Medicinal Chemistry, 2010, 45 (6), pp.2480-2488. ⟨10.1016/j.ejmech.2010.02.033⟩ Article dans une revue hal-03114812v1
	Design, synthesis and evaluation of progesterone–adenine hybrids as bivalent inhibitors of P-glycoprotein-mediated multidrug efflux Wael Zeinyeh , Ghina Alameh , Sylvie Radix , Catherine Grenot , Charles Dumontet Bioorganic and Medicinal Chemistry Letters, 2010, 20 (10), pp.3165 - 3168. ⟨10.1016/j.bmcl.2010.03.085⟩ Article dans une revue hal-01800193v1
	Synthesis and modulation properties of imidazo[4,5-b]pyridin-7-one and indazole-4,7-dione derivatives towards the Cryptosporidium parvum CpABC3 transporter Wael Zeinyeh , Hexue Xia , Philippe Lawton , Sylvie Radix , Christelle Marminon European Journal of Medicinal Chemistry, 2010, 45 (6), pp.2480 - 2488. ⟨10.1016/j.ejmech.2010.02.033⟩ Article dans une revue hal-01800190v1
	Regioselective N-alkylation of imidazo[4,5-b]pyridine-4-oxide derivatives: an experimental and DFT study Wael Zeinyeh , Julien Pilmé , Sylvie Radix , Nadia Walchshofer Tetrahedron Letters, 2009, 50 (16), pp.1828 - 1833. ⟨10.1016/j.tetlet.2009.02.006⟩ Article dans une revue hal-01800189v1
	A Simple and High-Yield Route to N-9-purinyl-acetic Acid Derivatives Coupled with Amino Acids Marie-Emmanuelle Million , Sylvie Radix , Sébastien Marrot , Magali Imbert , Joëlle Paris Letters in Organic Chemistry, 2008, 5 (6), pp.484 - 489. ⟨10.2174/157017808785740408⟩ Article dans une revue hal-01800186v1
	Total synthesis of two natural phenanthrenes: confusarin and a regioisomer Sylvie Radix , Roland Barret Tetrahedron, 2007, 63 (50), pp.12379 - 12387. ⟨10.1016/j.tet.2007.09.052⟩ Article dans une revue hal-01800184v1
	Synthesis of [6,n] cis-fused ring compounds via Cr-mediated dearomatisation–ring-closing metathesis E. Peter Kündig , Alejandro Bellido , Krishna Kaliappan , Andrew Pape , Sylvie Radix Organic & Biomolecular Chemistry, 2006, 4 (2), pp.342 - 351. ⟨10.1039/b513261d⟩ Article dans une revue hal-01800180v1
	Rational design of inhibitors of the cryptosporidium parvum ATP-binding cassette 3 protein. R. Terreux , P. Iawton , S. Radix , D. Deruaz , M. Lussignol Abstracts of Papers of the American Chemical Society, 2005, 229, pp.U179-U179 Article dans une revue hal-00314914v1
	A Regioselective Route to 5- and 6-Azaindoles Thierry Lomberget , Sylvie Radix , Roland Barret SYNLETT, 2005, 13, pp.2080 - 2082. ⟨10.1055/s-2005-871946⟩ Article dans une revue hal-01800182v1
	Trifluoromethylated Vinylic and Aromatic Compounds from α-(Trifluoromethyl)allyl Alcohols Sylvie Radix-Large , Stéphanie Kucharski , Bernard R. Langlois Synthesis: Journal of Synthetic Organic Chemistry, 2004, 3, pp.456 - 465. ⟨10.1055/s-2004-815928⟩ Article dans une revue hal-01800179v1
	Efficient Access to Fused Ring Compounds via Dearomatization/Ring-Closing Metathesis E. Peter Kündig , Alejandro Bellido , Krishna Kaliappan , Andrew Pape , Sylvie Radix SYNLETT, 2003, 15, pp.2407 - 2409. ⟨10.1055/s-2003-43330⟩ Article dans une revue hal-01800173v1
	Fluoride-assisted trifluoromethylation of aromatic thiones with (trifluoromethyl)trimethylsilane Sylvie Large-Radix , Thierry Billard , Bernard R. Langlois Journal of Fluorine Chemistry, 2003, 124 (2), pp.147 - 149. ⟨10.1016/S0022-1139(03)00203-3⟩ Article dans une revue hal-01800170v1
	Rearrangement of Oxasphiroheptanes to Cyclohexanones Mediated by Lithium Iodide Bouyssi Didier , Marcello Cavicchioli , Sylvie Large , Monteiro Nuno , Geneviève Balme SYNLETT, 2000, 2000 (05), pp.0749 - 0751. ⟨10.1055/s-2000-6606⟩ Article dans une revue hal-01800154v1
	Nucleophilic Trifluoromethylation of Carbonyl Compounds and Disulfides with Trifluoromethane and Silicon-Containing Bases Sylvie Large , Nicolas Roques , Bernard R. Langlois Journal of Organic Chemistry, 2000, 65 (26), pp.8848 - 8856. ⟨10.1021/jo000150s⟩ Article dans une revue hal-01800146v1
	Electrophilic Trifluoromethylation of Vinyl Sulfides Bernard R. Langlois , Thierry Billard , Sophie Guérin , Sylvie Large , Nathalie Roidot-Perol Phosphorus, Sulfur, and Silicon and the Related Elements, 1999, 153 (1), pp.323 - 324. ⟨10.1080/10426509908546452⟩ Article dans une revue hal-01800163v1
	Synthesis of Trifluoromethyl Selenides Thierry Billard , Bernard R. Langlois , Sylvie Large Phosphorus, Sulfur, and Silicon and the Related Elements, 1998, 136 (1), pp.521 - 524. ⟨10.1080/10426509808545987⟩ Article dans une revue hal-01800167v1
	An unprecedented access to trifluoromethylthiosugar derivatives from thiocyanate precursors upon treatment with trifluoromethyltrimethylsilane Marie-Noëlle Bouchu , Sylvie Large , Michaela Steng , Bernard R. Langlois , Jean-Pierre Praly Carbohydrate Research, 1998, 314 (1-2), pp.37 - 45. ⟨10.1016/S0008-6215(98)00289-4⟩ Article dans une revue hal-01800131v1
	Preparation of trifluoromethyl sulfides or selenides from trifluoromethyl trimethylsilane and thiocyanates or selenocyanates Thierry Billard , Sylvie Large , Bernard R. Langlois Tetrahedron Letters, 1997, 38 (1), pp.65 - 68. ⟨10.1016/S0040-4039(96)02216-2⟩ Article dans une revue hal-01800102v1
	A New Route to Thio- and Selenosulfonates from Disulfides and Diselenides. Application to the Synthesis of New Thio- and Selenoesters of Triflic Acid Thierry Billard , Bernard R. Langlois , Sylvie Large , Daniel Anker , Nathalie Roidot Journal of Organic Chemistry, 1996, 61 (21), pp.7545 - 7550. ⟨10.1021/jo960619c⟩ Article dans une revue hal-01800094v1

Sylvie RADIX

Présentation

Publications

P143 Clinical observation leads to the synthesis of BG185, a new antistaphylococcal compound

Solvent- and metal-free hydroboration of alkynes under microwave irradiation

Synthesis and biological evaluation of new dipicolylamine zinc chelators as metallo-β-lactamase inhibitors

Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors

Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles

Synthesis and preclinical evaluation of TPA-based zinc chelators as metallo-β-lactamase inhibitors

N,N′-disubstituted cinnamamide derivatives potentiate ciprofloxacin activity against overexpressing NorA efflux pump Staphylococcus aureus 1199B strains

Unsymmetrical α,ω-end-functionalized oligo(cyclohexylidenes): efficient synthesis and conformational analysis

Deoxycholic acid derivatives as inhibitors of P-glycoprotein-mediated multidrug efflux

Progesterone–adenine hybrids as bivalent inhibitors of P-glycoprotein-mediated multidrug efflux: Design, synthesis, characterization and biological evaluation

Synthesis and modulation properties of imidazo[4,5-b]pyridin-7-one and indazole-4,7-dione derivatives towards the Cryptosporidium parvum CpABC3 transporter

Design, synthesis and evaluation of progesterone–adenine hybrids as bivalent inhibitors of P-glycoprotein-mediated multidrug efflux

Synthesis and modulation properties of imidazo[4,5-b]pyridin-7-one and indazole-4,7-dione derivatives towards the Cryptosporidium parvum CpABC3 transporter

Regioselective N-alkylation of imidazo[4,5-b]pyridine-4-oxide derivatives: an experimental and DFT study

A Simple and High-Yield Route to N-9-purinyl-acetic Acid Derivatives Coupled with Amino Acids

Total synthesis of two natural phenanthrenes: confusarin and a regioisomer

Synthesis of [6,n] cis-fused ring compounds via Cr-mediated dearomatisation–ring-closing metathesis

Rational design of inhibitors of the cryptosporidium parvum ATP-binding cassette 3 protein.

A Regioselective Route to 5- and 6-Azaindoles

Trifluoromethylated Vinylic and Aromatic Compounds from α-(Trifluoro­methyl)allyl Alcohols

Efficient Access to Fused Ring Compounds via Dearomatization/Ring-Closing Metathesis

Fluoride-assisted trifluoromethylation of aromatic thiones with (trifluoromethyl)trimethylsilane

Rearrangement of Oxasphiroheptanes to Cyclohexanones Mediated by Lithium Iodide

Nucleophilic Trifluoromethylation of Carbonyl Compounds and Disulfides with Trifluoromethane and Silicon-Containing Bases

Electrophilic Trifluoromethylation of Vinyl Sulfides

Synthesis of Trifluoromethyl Selenides

An unprecedented access to trifluoromethylthiosugar derivatives from thiocyanate precursors upon treatment with trifluoromethyltrimethylsilane

Preparation of trifluoromethyl sulfides or selenides from trifluoromethyl trimethylsilane and thiocyanates or selenocyanates

A New Route to Thio- and Selenosulfonates from Disulfides and Diselenides. Application to the Synthesis of New Thio- and Selenoesters of Triflic Acid

Trifluoromethylated Vinylic and Aromatic Compounds from α-(Trifluoromethyl)allyl Alcohols