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Design of $\alpha$7 nicotinic acetylcholine receptor ligands in quinuclidine, tropane and quinazoline series. Chemistry, molecular modeling, radiochemistry, in vitro and in rats evaluations of a [$^{18}$F] quinuclidine derivative

Sylvie Mavel , Frédéric Pin , Johnny Vercouillie , Aziz Ouach , Zuhal Gulhan , et al.
European Journal of Medicinal Chemistry, 2014, 82, pp.214 - 224. ⟨10.1016/j.ejmech.2014.04.057⟩
Article dans une revue hal-01826403v1
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1H-13C NMR-based urine metabolic profiling in autism spectrum disorders.

Sylvie Mavel , Lydie Nadal-Desbarats , Hélène Blasco , Frédérique Bonnet-Brilhault , Catherine Barthélémy , et al.
Talanta, 2013, 114, pp.95-102. ⟨10.1016/j.talanta.2013.03.064⟩
Article dans une revue inserm-00908930v1
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1H-13C NMR-based urine metabolic profiling in autism spectrum disorders.

Sylvie Mavel , Lydie Nadal-Desbarats , Hélène Blasco , Frédérique Bonnet-Brilhault , Catherine Barthélémy , et al.
Talanta, 2013, 114, pp.95-102. ⟨10.1016/j.talanta.2013.03.064⟩
Article dans une revue inserm-00908985v1

The Metabolic Disturbances of Motoneurons Exposed to Glutamate

Sylvie Mavel , Blandine Madji Hounoum , Hélène Blasco , Emmanuelle Coque , Patrick Vourc’h , et al.
Molecular Neurobiology, 2018, ⟨10.1007/s12035-018-0945-8⟩
Article dans une revue hal-01826389v1
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Metabolomics Study of Urine in Autism Spectrum Disorders Using a Multiplatform Analytical Methodology.

Binta Diémé , Sylvie Mavel , Hélène Blasco , Gabriele Tripi , Frédérique Bonnet-Brilhault , et al.
Journal of Proteome Research, 2015, 14, pp.5273-82. ⟨10.1021/acs.jproteome.5b00699⟩
Article dans une revue hal-02104565v1

Metabolomics Study of Urine in Autism Spectrum Disorders Using a Multiplatform Analytical Methodology

Sylvie Mavel , Binta Diémé , Hélène Blasco , Gabriele Tripi , Frédérique Bonnet-Brilhault , et al.
Journal of Proteome Research, 2015, 14 (12), pp.5273 - 5282. ⟨10.1021/acs.jproteome.5b00699⟩
Article dans une revue hal-01826402v1

3-Biphenylimidazo[1,2-a]pyridines or [1,2-b]pyridazines and analogues, novel Flaviviridae inhibitors

Cécile Gueiffier , Simone Musiu , Nicolas Henry , Jean-Baptiste Véron , Sylvie Mavel , et al.
European Journal of Medicinal Chemistry, 2013, 64, pp.448 - 463. ⟨10.1016/j.ejmech.2013.03.054⟩
Article dans une revue istex hal-01826405v1

Synthesis and in vitro evaluation of fluorinated diphenyloxide derivatives and sulfur analogs as serotonin transporter ligands

Sylvie Mavel , Nathalie Meheux , Denis Guilloteau , Patrick Emond , Antoine Lefèvre , et al.
Bioorganic and Medicinal Chemistry, 2010, 18 (1), pp.236 - 241. ⟨10.1016/j.bmc.2009.10.062⟩
Article dans une revue istex hal-01826417v1
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NSC-34 Motor Neuron-Like Cells Are Unsuitable as Experimental Model for Glutamate-Mediated Excitotoxicity

Blandine Madji Hounoum , Patrick Vourc’h , Romain Félix , Philippe Corcia , Franck Patin , et al.
Frontiers in Cellular Neuroscience, 2016, 10, pp.118. ⟨10.3389/fncel.2016.00118⟩
Article dans une revue hal-01826430v1
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Validation of a global quantitative analysis methodology of tryptophan metabolites in mice using LC-MS

Antoine Lefèvre , Sylvie Mavel , Lydie Nadal-Desbarats , Laurent Galineau , Sylvie Attucci , et al.
Talanta, 2019, 195, pp.593-598. ⟨10.1016/j.talanta.2018.11.094⟩
Article dans une revue hal-02291264v3

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S

Matthieu Galibert , Mylène Wartenberg , Fabien Lecaille , Ahlame Saidi , Sylvie Mavel , et al.
European Journal of Medicinal Chemistry, 2018, 144, pp.201-210. ⟨10.1016/j.ejmech.2017.12.012⟩
Article dans une revue hal-03677245v1

Analytical methodology for metabolomics study of adherent mammalian cells using NMR, GC-MS and LC-HRMS

Sylvie Mavel , Blandine Madji Hounoum , Hélène Blasco , Lydie Nadal-Desbarats , Binta Diémé , et al.
Analytical and Bioanalytical Chemistry, 2015, 407 (29), pp.8861 - 8872. ⟨10.1007/s00216-015-9047-x⟩
Article dans une revue hal-01826394v1

Reaction of 4-Bromobenzyl-3-methyl-1,2-oxazin-6-ones with Primary Aliphatic Amines. Synthesis and Structural Determination of New Oxazine and Isoxazole Derivatives

Jacques Couquelet , Monique Bebot , Pascal Coudert , Fernand Leal , Jacques Métin , et al.
Heterocycles, 1998, 48 (3), pp.451. ⟨10.3987/COM-97-8050⟩
Article dans une revue hal-02883844v1

Aromatic fluoro-de-triazenation with boron trifluoride diethyl etherate under non-protic acid conditions

Mitja Kovac , Marko Anderluh , Johnny Vercouillie , Denis Guilloteau , Patrick Emond , et al.
Journal of Fluorine Chemistry, 2013, 147 (15), pp.5 - 9. ⟨10.1016/j.jfluchem.2013.01.012⟩
Article dans une revue istex hal-01841283v1
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Wildtype motoneurons, ALS-Linked SOD1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling

Sylvie Mavel , Blandine Madji Hounoum , Emmanuelle Coque , Franck Patin , Patrick Vourc'H , et al.
Glia, 2017, 65 (4), pp.592 - 605. ⟨10.1002/glia.23114⟩
Article dans une revue hal-01826428v1
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Liquid chromatography–high-resolution mass spectrometry-based cell metabolomics: Experimental design, recommendations, and applications

Blandine Madji Hounoum , Hélène Blasco , Patrick Emond , Sylvie Mavel
Trends in Analytical Chemistry, 2016, 75, pp.118 - 128. ⟨10.1016/j.trac.2015.08.003⟩
Article dans une revue hal-01841271v1
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Maternal Rat Metabolomics: Amniotic Fluid and Placental Metabolic Profiling Workflows

Alexandra Bourdin-Pintueles , Laurent Galineau , Lydie Nadal-Desbarats , Camille Dupuy , Sylvie Bodard , et al.
Journal of Proteome Research, 2021, 20 (8), pp.3853-3864. ⟨10.1021/acs.jproteome.1c00145⟩
Article dans une revue hal-03954760v1
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Validation of metabolomics analysis of human perilymph fluid using liquid chromatography-mass spectroscopy

Sylvie Mavel , Antoine Lefèvre , David Bakhos , Diane Dufour-Rainfray , Hélène Blasco , et al.
Hearing Research, 2018, 367, pp.129-136. ⟨10.1016/j.heares.2018.05.016⟩
Article dans une revue hal-03955606v1
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Workflow methodology for rat brain metabolome exploration using NMR, LC–MS and GC–MS analytical platforms

Binta Diémé , Antoine Lefèvre , Lydie Nadal-Desbarats , Laurent Galineau , Blandine Madji Hounoum , et al.
Journal of Pharmaceutical and Biomedical Analysis, 2017, 142, pp.270 - 278. ⟨10.1016/j.jpba.2017.03.068⟩
Article dans une revue hal-01826526v1

Combined 1 H-NMR and 1 H– 13 C HSQC-NMR to improve urinary screening in autism spectrum disorders

Sylvie Mavel , Lydie Nadal-Desbarats , Nacima Aïdoud , Patrick Emond , Hélène Blasco , et al.
Analyst, 2014, 139 (13), pp.3460 - 3468. ⟨10.1039/c4an00552j⟩
Article dans une revue hal-01826404v1

Biomarkers in amyotrophic lateral sclerosis: combining metabolomic and clinical parameters to define disease progression

Sylvie Mavel , H. Blasco , Lydie Nadal-Desbarats , P. Pradat , P. Gordon , et al.
European Journal of Neurology, 2016, 23 (2), pp.346 - 353. ⟨10.1111/ene.12851⟩
Article dans une revue istex hal-01841180v1
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Identification of metabolic pathway disturbances using multimodal metabolomics in autistic disorders in a Middle Eastern population

Sylvie Mavel , Tania Bitar , Patrick Emond , Lydie Nadal-Desbarats , Antoine Lefèvre , et al.
Journal of Pharmaceutical and Biomedical Analysis, 2018, 152, pp.57 - 65. ⟨10.1016/j.jpba.2018.01.007⟩
Article dans une revue hal-01826422v1
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GC-MS-based urine metabolic profiling of autism spectrum disorders.

Patrick Emond , Sylvie Mavel , Nacima Aïdoud , Lydie Nadal-Desbarats , Frédéric Montigny , et al.
Analytical and Bioanalytical Chemistry, 2013, 405 (15), pp.5291-300. ⟨10.1007/s00216-013-6934-x⟩
Article dans une revue inserm-00908948v1

Metabolomics in Cerebrospinal Fluid of Patients with Amyotrophic Lateral Sclerosis: An Untargeted Approach via High-Resolution Mass Spectrometry

Sylvie Mavel , Hélène Blasco , Philippe Corcia , Pierre-François Pradat , Cinzia Bocca , et al.
Journal of Proteome Research, 2013, 12 (8), pp.3746 - 3754. ⟨10.1021/pr400376e⟩
Article dans une revue hal-01841226v1

Untargeted 1H-NMR metabolomics in CSF: Toward a diagnostic biomarker for motor neuron disease

Sylvie Mavel , H. Blasco , Lydie Nadal-Desbarats , P. Pradat , P. Gordon , et al.
Neurology, 2014, 82 (13), pp.1167 - 1174. ⟨10.1212/WNL.0000000000000274⟩
Article dans une revue hal-01826432v1

3D QSAR study, synthesis, and in vitro evaluation of (+)-5-FBVM as potential PET radioligand for the vesicular acetylcholine transporter (VAChT)

Sylvie Mavel , Mitja Kovac , Winnie Deuther-Conrad , Nathalie Méheux , Jana Glöckner , et al.
Bioorganic and Medicinal Chemistry, 2010, 18 (21), pp.7659 - 7667. ⟨10.1016/j.bmc.2010.08.028⟩
Article dans une revue istex hal-01826409v1
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Optimization of Sample Preparation for Metabolomics Exploration of Urine, Feces, Blood and Saliva in Humans Using Combined NMR and UHPLC-HRMS Platforms

Cécile Martias , Nadine Baroukh , Sylvie Mavel , Hélène Blasco , Antoine Lefèvre , et al.
Molecules, 2021, 26 (14), pp.4111. ⟨10.3390/molecules26144111⟩
Article dans une revue hal-03954853v1

Validation of metabolomics analysis of human perilymph fluid using liquid chromatography-mass spectroscopy

Sylvie Mavel , Antoine Lefèvre , David Bakhos , Diane Dufour-Rainfray , Hélène Blasco , et al.
Hearing Research, 2018, ⟨10.1016/j.heares.2018.05.016⟩
Article dans une revue hal-01826420v1

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S

Matthieu Galibert , Mylène Wartenberg , Fabien Lecaille , Ahlame Saidi , Sylvie Mavel , et al.
European Journal of Medicinal Chemistry, 2018, 144, pp.201 - 210. ⟨10.1016/j.ejmech.2017.12.012⟩
Article dans une revue hal-01702303v1

QSAR study and synthesis of new phenyltropanes as ligands of the dopamine transporter (DAT)

Sylvie Mavel , Zoya Mincheva , Nathalie Méheux , Yvan Carcenac , Denis Guilloteau , et al.
Bioorganic and Medicinal Chemistry, 2012, 20 (4), pp.1388 - 1395. ⟨10.1016/j.bmc.2012.01.014⟩
Article dans une revue istex hal-01826407v1