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Pharmacocinétique de la teicoplanine chez le sujet âgé : construction d'un modèle pour le suivi thérapeutique

 Laurent Bourguignon , Sylvain Goutelle , P. Bouniot , A. Guillermet , J. Burdin de Saint-Martin , et al.
Journal de Pharmacie Clinique, 2008, 27 (3), pp.189-194
Article dans une revue hal-00428103v1

Mechanisms of drug-drug interaction between rifampicin and fusidic acid

 Florianne Bel , Laurent Bourguignon , Michel Tod , Tristan Ferry , Sylvain Goutelle
British Journal of Clinical Pharmacology, 2017, 83 (8), pp.1862-1864. ⟨10.1111/bcp.13277⟩
Article dans une revue hal-01911527v1

Pharmacokinetic Drug Interaction Between Cyclosporine and Imatinib in Bone Marrow Transplant Children and Model-Based Reappraisal of Imatinib Drug Interaction Profile

 Nathalie Bleyzac , K. Kebaili , V. Mialou , Y. Bertrand , Sylvain Goutelle
Therapeutic Drug Monitoring, 2014, 36, pp.724-729
Article dans une revue hal-02072953v1

Exposure to anticholinergic and sedative drugs, risk of falls, and mortality: an elderly inpatient, multicenter cohort

 V. Dauphinot , R. Faure , S. Omrani , Sylvain Goutelle , Laurent Bourguignon , et al.
Journal of clinical psychopharmacology, 2014, 34, pp.565-70. ⟨10.1097/JCP.0000000000000195⟩
Article dans une revue hal-02071559v1

Determinants of torsades de pointes in older patients with drug-associated long QT syndrome: a case-control study

 Sylvain Goutelle , E. Sidolle , M. Ducher , J. Caron , Q. Timour , et al.
Drugs & aging, 2014, 31, pp.601-9
Article dans une revue hal-02046809v1

A Prediction Model of Drug Exposure in Cirrhotic Patients According to Child-Pugh Classification

 J. Steelandt , E. Jean-Bart , Sylvain Goutelle , M. Tod
Clinical Pharmacokinetics, 2015, 54, pp.1245-58. ⟨10.1007/s40262-015-0288-9⟩
Article dans une revue hal-02018973v1

Therapeutic Drug Monitoring of Antibiotic Drugs in Patients Receiving Continuous Renal Replacement Therapy or Intermittent Hemodialysis: A Critical Review

 Elodie Matusik , Clément Boidin , Arnaud Friggeri , Jean-Christophe Richard , Laurent Bitker , et al.
Therapeutic Drug Monitoring, 2022, 44 (1), pp.86-102. ⟨10.1097/FTD.0000000000000941⟩
Article dans une revue hal-04531627v1

Pharmacocinétique de l'amikacine chez l'adulte : une hétérogénéité qui remet en cause le calcul de la dose basé sur le poids

 Laurent Bourguignon , Sylvain Goutelle , C. Gérard , A. Guillermet , J. Burdin de Saint Martin , et al.
Thérapie, 2009, 64 (1), pp.189-194
Article dans une revue hal-00428392v1
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Mathematical modeling of pulmonary tuberculosis therapy: insights from a prototype model with rifampin

 Sylvain Goutelle , Laurent Bourguignon , Roger W. Jelliffe , John E. Conte , Pascal Maire
Journal of Theoretical Biology, 2011, ⟨10.1016/j.jtbi.2011.05.013⟩
Article dans une revue istex hal-00709543v1

Population Modeling and Monte Carlo Simulation Study of the Pharmacokinetics and Antituberculosis Pharmacodynamics of Rifampin in Lungs

 Sylvain Goutelle , Laurent Bourguignon , P. Maire , M. van Guilder , J.-D. Conte , et al.
Antimicrobial Agents and Chemotherapy, 2009, 53(7), pp.2974-2981
Article dans une revue hal-00539373v1

Genotype-Based Quantitative Prediction of Drug Exposure for Drugs Metabolized by CYP2D6

 Michel Tod , Sylvain Goutelle , M.C. Gagnieu , Working Group The Genophar Ii
Clinical Pharmacology and Therapeutics, 2011, 90, pp.582-587
Article dans une revue hal-00698266v1

Prevalence and Risk Factors of Drug-Associated Corrected QT Prolongation in Elderly Hospitalized Patients: Results of a Retrospective Analysis of Data Obtained Over 6 Months

 O. Maison , B. de La Gastine , L. Dayot , Sylvain Goutelle
Drugs & aging, 2017, 34, pp.545-553. ⟨10.1007/s40266-017-0467-5⟩
Article dans une revue hal-01943811v1
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Defining standard and high dosages for β-lactam agents administered by intermittent, prolonged or continuous infusion: a PK/PD simulation study

 Sylvain Goutelle , Vincent Jullien , Jean-Pierre Bru , Vincent Cattoir , Rémy Gauzit , et al.
Journal of Antimicrobial Chemotherapy, 2023, 78 (11), pp.2762-2769. ⟨10.1093/jac/dkad300⟩
Article dans une revue hal-04279023v1
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Population Pharmacokinetics and Dosing Simulation of Vancomycin Administered by Continuous Injection in Critically Ill Patient

 Romain Garreau , Benoît Falquet , Lisa Mioux , Laurent Bourguignon , Tristan Ferry , et al.
Antibiotics, 2021, 10 (10), pp.1228. ⟨10.3390/antibiotics10101228⟩
Article dans une revue hal-03624447v1

Amikacin Initial Dose in Critically Ill Patients: a Nonparametric Approach To Optimize A Priori Pharmacokinetic/Pharmacodynamic Target Attainments in Individual Patients

 Clément Boidin , Laurent Bourguignon , Sabine Cohen , Claire Roger , Jean-Yves Lefrant , et al.
Antimicrobial Agents and Chemotherapy, 2019, 63 (11), pp.e00993-19. ⟨10.1128/AAC.00993-19⟩
Article dans une revue hal-02798085v1

Is Trough Concentration of Vancomycin Predictive of the Area Under the Curve? A Clinical Study in Elderly Patients

 A. Bel Kamel , Laurent Bourguignon , M. Marcos , M. Ducher , Sylvain Goutelle
Therapeutic Drug Monitoring, 2017, 39, pp.83-87. ⟨10.1097/FTD.0000000000000359⟩
Article dans une revue hal-02049657v1

Implications of using the MDRD or CKD-EPI equation instead of the Cockcroft-Gault equation for estimating renal function and drug dosage adjustment in elderly patients

 E. Cartet-Farnier , L. Goutelle-Audibert , P. Maire , B. de La Gastine , Sylvain Goutelle
Fundamental & Clinical Pharmacology, 2017, 31, pp.110-119. ⟨10.1111/fcp.12241⟩
Article dans une revue hal-02049666v1

A pharmacometric pulmonary model predicting the extent and rate of distribution from plasma to epithelial lining fluid and alveolar cells-using rifampicin as an example

 O. Clewe , Sylvain Goutelle , Jr. Conte , Ush. Simonsson
European Journal of Clinical Pharmacology, 2015, 71 (3), pp.313-9. ⟨10.1007/s00228-014-1798-3⟩
Article dans une revue hal-02044963v1

Probable Drug Interaction Between Intravenous Ciprofloxacin and Mycophenolate Mofetil in a Bone Marrow Transplant Recipient

 Sylvain Goutelle , V. Mialou , A. Gouraud , F. Parant , N. Bleyzac
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2011, 31(1), pp.36-40
Article dans une revue hal-00697909v1

Comparison of Four Renal Function Estimation Equations for Pharmacokinetic Modeling of Gentamicin in Geriatric Patients

 N. Charhon , M.N. Neely , Laurent Bourguignon , P. Maire , R.W. Jelliffe , et al.
Antimicrobial Agents and Chemotherapy, 2012, 56 (4), pp.1862-1869. ⟨10.1128/AAC.05634-11⟩
Article dans une revue hal-00698373v1

The Role of Antibiotics in Modulating Virulence in Staphylococcus aureus

 Elisabeth Hodille , Warren Rose , Binh An Diep , Sylvain Goutelle , Gérard Lina , et al.
Clinical Microbiology Reviews, 2017, 30 (4), pp.887-917. ⟨10.1128/CMR.00120-16⟩
Article dans une revue hal-01911294v1
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An Investigation of O-Demethyl Tramadol/Tramadol Ratio for Cytochrome P450 2D6 Phenotyping: The CYTRAM Study

 Blandine de la Gastine , Soizic Percevault , Laurent Varin , Nicolas Richard , Fabienne Fobe , et al.
Pharmaceutics, 2022, 14 (10), pp.2177. ⟨10.3390/pharmaceutics14102177⟩
Article dans une revue hal-03842709v1

Subcutaneous administration of levetiracetam in geriatrics

 O. Maison , B. de La Gastine , L. Peter-Derex , C. Berger , Sylvain Goutelle
Revue Neurologique, 2015, 171, pp.398-399
Article dans une revue hal-02025598v1

The Case for Using Higher Doses of First Line Anti-Tuberculosis Drugs to Optimize Efficacy

 Sylvain Goutelle , Laurent Bourguignon , P. Maire , R. W. Jelliffe , M. Neely
Current Pharmaceutical Design, 2014, 20, pp.6191-6206
Article dans une revue hal-02046812v1

Assessing the Combined Antibacterial Effect of Isoniazid and Rifampin on Four Mycobacterium tuberculosis Strains Using In Vitro Experiments and Response-Surface Modeling

 Charlotte Genestet , Florence Ader , Catherine Pichat , Gérard Lina , Oana Dumitrescu , et al.
Antimicrobial Agents and Chemotherapy, 2018, 62 (1), ⟨10.1128/AAC.01413-17⟩
Article dans une revue hal-01908846v1

Model-Based Determination of Effective Blood Concentrations of Cyclosporine for Neutrophil Response in the Treatment of Severe Aplastic Anemia in Children

 M. Philippe , E. Henin , Y. Bertrand , D. Plantaz , Sylvain Goutelle , et al.
AAPS Journal, 2015, 17 (5), pp.1157-67. ⟨10.1208/s12248-015-9779-8⟩
Article dans une revue hal-02025629v1

Daptomycin Physiology-Based Pharmacokinetic Modeling to Predict Drug Exposure and Pharmacodynamics in Skin and Bone Tissues

 Romain Garreau , Damien Montange , Antoine Grillon , François Jehl , Tristan Ferry , et al.
Clinical Pharmacokinetics, 2022, 61 (10), pp.1443-1456. ⟨10.1007/s40262-022-01168-5⟩
Article dans une revue hal-04067357v1

Prescriptions analysis by clinical pharmacists in the post-operative period: a 4-year prospective study.

 B. Charpiat , Sylvain Goutelle , M. Schoeffler , F. Aubrun , J.-P. Viale , et al.
Acta Anaesthesiologica Scandinavica, 2012, 56 (8), pp.1047-51. ⟨10.1111/j.1399-6576.2011.02644.x⟩
Article dans une revue istex hal-01057865v1

Population pharmacokinetics of daptomycin in patients with bone and joint infection: minimal effect of rifampicin co-administration and confirmation of a sex difference

 Romain Garreau , Romain Bricca , Marie-Claude Gagnieu , Sandrine Roux , Anne Conrad , et al.
Journal of Antimicrobial Chemotherapy, 2021, 76 (5), pp.1250-1257. ⟨10.1093/jac/dkab006⟩
Article dans une revue hal-03624877v1

Comparison of the static in vivo approach to a physiologically based pharmacokinetic approach for metabolic drug-drug interactions prediction

 M. Tod , P.B. Pierrillas , Laurent Bourguignon , Sylvain Goutelle
International Journal of Pharmacokinetics, 2016, pp.1-10
Article dans une revue hal-02049898v1
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