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stephane uroz

Directeur de Recherche (DR2) Directeur Scientifique et Technique du Labex ARBRE depuis janvier 2022
30
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Affiliations actuelles
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Identifiants chercheurs

Présentation

**BIO:** I received my PhD in Microbial Ecology from the University of Paris XI (Orsay) in 2004 with Yves DESSAUX and Phil OGER as my advisers. My PhD research project was focused on the biological stability of the quorum sensing signal molecules, especially the N-acyl homoserine lactone class based on the hypothesis that these molecules need to be degraded to act as a signal, possibly by bacteria naturally occurring in the soil.To verify this hypothesis, I combined classical microbiology, molecular tools, genetic, biochemistry and chemistry. I performed my PhD in three places : in the lab ‘Interactions Plant Microorganisms’ at the Institute of Plant Sciences (ISV, Gif-sur-Yvette ; adviser : [Yves Dessaux](http://www.isv.cnrs-gif.fr/recherche/yd/yd.html)) ; in the lab of “Sciences de la Terre” at Normal School (ENS, Lyon ; adviser : Phil Oger) and at the Institute of Infections and Immunity at University of Nottingham (Queen’s Medical Centre, Nottingham; advisers: [Paul Williams, Miguel Camara and Siri Ram Chhabra](http://www.nottingham.ac.uk/quorum/))(European Union Marie Curie programme). The 15th of october 2004, I defended my thesis (Jury: P. SIMONET, S. REVERCHON, D. HAAS, M. DUBOW, Y. DESSAUX, P. OGER). The 22th of october 2004, I was hired as Junior Research associate (CR2) in the EFPA (now ECODIV) department of the French National Institute for Agricultural Reasearch (INRA), at the interface between two research units: i) The “Tree microbes interactions” (IAM, UMR1136) unit and ii) the “Biogeochemical cycles in forest ecosystems” (BEF, UR1138) unit. I am member of the Ecogenomic and mineral weathering teams. In January 2009, I became Research associate (CR1). The 24th of februrary 2014, I defended my HDR (Habilitation à diriger des recherches) entitled “Ecology of biotic and abiotic interactions of the forest soil bacterial communities: characterization of the actors, mechanims and related genes” (Jury: C. MOUGEL, P. SIMONET, S. VUILLEMIER, R. MARMEISSE, L. MOULIN, P. LEBLOND, E. GELHAYE, P. OGER and P. FREY-KLETT). I was appointed INRA Research Director (DR2) in december 2014. I was head of the Ecogenomics of interactions team in from January 2020 to december 2021. I was appointed Head of the Cluster[ of Excellence ARBRE (Advanced Research on the Biology of Tree Biology and Forest Ecosystems)](http://mycor.nancy.inra.fr/ARBRE) with Myriam LEGAY and Mathieu PETRISSANS. My main collaborator is **Marie-Pierre TURPAULT** (Geochemist and mineralogist) and Cintia BLANCO NOUCHE (PhD). I am also involved in several projects related to microbial ecology, interactions between bacteria/fungi and signalling between bacteria with the colleagues of the **Ecogenomic team** (**M. BUEE, A. DEVEAU, F.MARTIN, L. AUER, E. MORIN**). **RESEARCH TOPICS:** My current projects, integrated in a more global questioning related to forest ecosystem functioning and sustainability, are linking genomics on model bacterial strains to microbial ecology: - **Forest soil as a reservoir of microbial biodiversity** (specific diversity by monogenic metagenomics, global approach by massive metagenomics and functional metagenomics) - Forest soil as a reservoir of **mineral weathering** bacteria (functional diversity, genetics, genomics link to biogeochemistry and mineralogy) - **Minerals and rocks** as microbial habitats (**mineralosphere**) - Microbial interactions and functions in the **rhizosphere and mycorrhizosphere** (e.g., quorum sensing ; competition) - Impact of **nutrient availability** (inorganic nutrients)/ soil type /tree species on bacterial communities - Impact of **drought** on the distribution and functioning of the bacterial communities - Impact of the microorganisms on the **nutrient cycle** (geomicrobiology) - **Genomics and genetics** of mineral weathering bacteria **COLLABORATIONS :** [Phil Oger](http://geologie.ens-lyon.fr/LST/spip.php?article50) (CNRS-ENS, Lyon), PE Courty (INRAE, Dijon), [Johan H.J. Leveau](http://plantpathology.ucdavis.edu/faculty/leveau/) (Univ. Davis, USA), [Wietse de Boer ](http://www.nioo.knaw.nl/users/wdeboer)(NIOO-KNAW, Netherlands),[ Jussi Heinonsalo](http://www.helsinki.fi/bioscience/myco/staff.htm) (Univ. Helsinki, Finland), Jean Armengaud (CEA-Marcoule, Bagnols-sur-Cèze), Cédric Paris (ENSAIA/UL, Vandoeuvre-les-Nancy).

Publications

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The non-ribosomal peptide synthetase-independent siderophore (NIS) rhizobactin produced by Caballeronia mineralivorans PML1(12) confers the ability to weather minerals

Cintia Blanco Nouche , Cédric Paris , Tiphaine Dhalleine , Philippe Oger , Marie-Pierre Turpault
Applied and Environmental Microbiology, 2023, 89 (10), pp.0045323. ⟨10.1128/aem.00453-23⟩
Article dans une revue hal-04297012v1

Genomic and transcriptomic characterization of the Collimonas quorum sensing genes and regulon

Stephane Uroz , Océane Geisler , Laure Fauchery , Raphaël Lami , Alice Rodrigues
FEMS Microbiology Ecology, 2022, 98 (11), ⟨10.1093/femsec/fiac100⟩
Article dans une revue hal-03915632v1
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The mineral weathering ability of Collimonas pratensis PMB3(1) involves a Malleobactin-mediated iron acquisition system

Laura Picard , Cédric Paris , Tiphaine Dhalleine , Emmanuelle Morin , Philippe Oger
Environmental Microbiology, 2022, 24 (2), pp. 784-802. ⟨10.1111/1462-2920.15508⟩
Article dans une revue hal-03194986v1
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Identification of a novel type of glucose dehydrogenase involved in the mineral weathering ability of Collimonas pratensis strain PMB3(1)

Laura Picard , Marie-Pierre M.-P. Turpault , P. Oger , Stephane Uroz
FEMS Microbiology Ecology, 2021, 97 (1), pp.fiaa232. ⟨10.1093/femsec/fiaa232⟩
Article dans une revue hal-03000681v1
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Dual transcriptomics and proteomics analyses of the early stage of interaction between Caballeronia mineralivorans PML1(12) and mineral

Stephane Uroz , Laura Picard , Marie-Pierre M.-P. Turpault , Lucas Auer , J. Armengaud
Environmental Microbiology, inPress, 22 (9), pp.3838-3862. ⟨10.1111/1462-2920.15159⟩
Article dans une revue hal-02902180v1
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Draft Genome Sequence of Collimonas pratensis Strain PMB3(1), an Effective Mineral-Weathering and Chitin-Hydrolyzing Bacterial Strain

Laura Picard , Philippe Oger , Marie-Pierre M.-P. Turpault , Stephane Uroz
Microbiology Resource Announcements, 2020, 9 (37), ⟨10.1128/MRA.00601-20⟩
Article dans une revue hal-02939115v1

Corrigendum to “Caballeronia mineralivorans sp. nov., isolated from oak-Scleroderma citrinum mycorrhizosphere” [Syst. Appl. Microbiol. 40 (2017) 345–351]

S. Uroz , Phil M. Oger
Systematic and Applied Microbiology, 2019, 42 (3), pp.423-424. ⟨10.1016/j.syapm.2019.03.001⟩
Article dans une revue hal-02122345v1
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Plant Symbionts Are Engineers of the Plant-Associated Microbiome

Stéphane Uroz , Pierre-Emmanuel Courty , P. Oger
Trends in Plant Science, 2019, 24 (10), pp.905-916. ⟨10.1016/j.tplants.2019.06.008⟩
Article dans une revue hal-02334474v1

Caballeronia mineralivorans sp. nov., isolated from oak-Scleroderma citrinum mycorrhizosphere.

Stéphane Uroz , P. Oger
Systematic and Applied Microbiology, 2017, 40 (6), pp.345-351. ⟨10.1016/j.syapm.2017.05.005⟩
Article dans une revue hal-01644024v1
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Specific impacts of beech and Norway spruce on the structure and diversity of the rhizosphere and soil microbial communities

S. Uroz , P. Oger , E. Tisserand , A. Cebron , M. -P. Turpault
Scientific Reports, 2016, 6 (1), pp.1-11. ⟨10.1038/srep27756⟩
Article dans une revue hal-01579579v1

Draft Genome Sequence of Burkholderia sp. Strain PML1(12), an Ectomycorrhizosphere-Inhabiting Bacterium with Effective Mineral-Weathering Ability

Stephane Uroz , Phil Oger
Genome Announcements, 2015, 3 (4), ⟨10.1128/genomeA.00798-15⟩
Article dans une revue hal-02916120v1

Correlation of the Abundance of Betaproteobacteria on Mineral Surfaces with Mineral Weathering in Forest Soils

C. Lepleux , M. Turpault , Phil M. Oger , P. Frey-Klett , S. Uroz
Applied and Environmental Microbiology, 2012, 78 (19), pp.7114-7119. ⟨10.1128/AEM.00996-12⟩
Article dans une revue hal-02122800v1

Distinct Ectomycorrhizospheres Share Similar Bacterial Communities as Revealed by Pyrosequencing-Based Analysis of 16S rRNA Genes

Stéphane Uroz , P. Oger , Emmanuelle Morin , P. Frey-Klett
Applied and Environmental Microbiology, 2012, 78 (8), pp.3020 - 3024. ⟨10.1128/AEM.06742-11⟩
Article dans une revue hal-01268355v1

Distinct Ectomycorrhizospheres Share Similar Bacterial Communities as Revealed by Pyrosequencing-Based Analysis of 16S rRNA Genes

Stephane Uroz , P. Oger , E. Morin , P. Frey-Klett
Applied and Environmental Microbiology, 2012, 78 (8), pp. 3020-3024. ⟨10.1128/AEM.06742-11⟩
Article dans une revue hal-02916135v1

Correlation of the Abundance of Betaproteobacteria on Mineral Surfaces with Mineral Weathering in Forest Soils

C. Lepleux , M. Turpault , P. Oger , P. Frey-Klett , Stephane Uroz
Applied and Environmental Microbiology, 2012, 78 (19), pp. 7114-7119. ⟨10.1128/AEM.00996-12⟩
Article dans une revue hal-02916134v1

Bacterial weathering and its contribution to nutrient cycling in temperate forest ecosystems

Stéphane Uroz , Philippe M. Oger , Cendrella Lepleux , Christelle Collignon , Pascale P. Frey-Klett
Research in Microbiology, 2011, 162 (9), pp.820-831. ⟨10.1016/j.resmic.2011.01.013⟩
Article dans une revue insu-00682028v1

Quorum Sensing and Quorum Quenching: The Yin and Yang of Bacterial Communication

Stéphane Uroz , Yves Dessaux , Phil M. Oger
ChemBioChem, 2009, 10 (2), pp.205-216. ⟨10.1002/cbic.200800521⟩
Article dans une revue hal-02122861v1
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A Rhodococcus qsdA-Encoded Enzyme Defines a Novel Class of Large-Spectrum Quorum-Quenching Lactonases

Stéphane S. Uroz , Phil M. Oger , Emilie Chapelle , Marie-Thérèse Adeline , Denis Faure
Applied and Environmental Microbiology, 2008, 74 (5), pp.1357-1366. ⟨10.1128/AEM.02014-07⟩
Article dans une revue hal-02665934v1

A Rhodococcus qsdA-encoded enzyme defines a novel class of large-spectrum quorum-quenching lactonases.

S. Uroz , Philippe M. Oger , E. Chapelle , M.-T. Adeline , D. Faure
Applied and Environmental Microbiology, 2008, 74, pp.1357-1366
Article dans une revue hal-00342712v1

N-acyl homoserine lactones are degraded via an amidolytic activity in Comamonas sp. strain D1.

Stéphane Uroz , Yves Dessaux , Philippe M. Oger , Siri Ram Chhabra , Miguel Cámara
Archives of Microbiology, 2006, 187 (3), pp.249-256. ⟨10.1007/s00203-006-0186-5⟩
Article dans une revue hal-00119105v1

N-Acylhomoserine lactone quorum-sensing molecules are modified and degraded by Rhodococcus erythropolis W2 by both amidolytic and novel oxidoreductase activities.

Stéphane Uroz , Siri Ram Chhabra , Miguel Cámara , Paul Williams , Philippe M. Oger
Microbiology, 2005, 151 (10), pp.3313-3322. ⟨10.1099/mic.0.27961-0⟩
Article dans une revue hal-00019097v1

Novel bacteria degrading N-acylhomoserine lactones and their use as quenchers of quorum-sensing-regulated functions of plant-pathogenic bacteria.

Stéphane Uroz , Cathy d'Angelo-Picard , Aurélien Carlier , Miena Elasri , Carine Sicot
Microbiology, 2003, 149 (8), pp.1981-1989. ⟨10.1099/mic.0.26375-0⟩
Article dans une revue hal-00135468v1

Screening for N-AHSL-Based-Signaling Interfering Enzymes

Stéphane Uroz , Phil M. Oger
METAGENOMICS: METHODS AND PROTOCOLS, 1539 (Chapter 18), Editions Springer, 15 p., 2017, Methods in Molecular Biology, 978-1-4939-6689-9. ⟨10.1007/978-1-4939-6691-2_18⟩
Chapitre d'ouvrage hal-01688921v1

Screening for N-AHSL-Based-Signaling Interfering Enzymes

Stéphane Uroz , Phil M. Oger
Metagenomics. Methods in Molecular Biology (Methods and Protocols), pp.203-217, 2010
Chapitre d'ouvrage hal-02122828v1

Forest tree species shape their soil microbiome

Stéphane S. Uroz , Phil Oger , Emilie Tisserand , Aurélie Cébron , Marie-Pierre M.-P. Turpault
Rhizosphere 4 congress, Jun 2015, Maastricht, Netherlands. 2015
Poster de conférence hal-02800245v1

Forest tree species shape their soil microbiome

Stéphane S. Uroz , Phil Oger , Emilie Tisserand , Aurélie Cébron , Marie-Pierre M.-P. Turpault
1. Global Soil Biodiversity Conference : Assessing Soil Biodiversity and its Role for Ecosystem Services, Dec 2014, Dijon, France. 2014
Poster de conférence hal-02796803v1

Caractérisation taxonomique et fonctionnelle des communautés bactériennes associées à la surface des minéraux : Combinaison d’approches non-cultivable et cultivable

Cendrella Lepleux , Stéphane S. Uroz , Marie-Pierre M.-P. Turpault , P. Oger , Pascale P. Frey-Klett
Congrès Ecole Thématique Expert Génomique Environnementale (ETEGE), 2012, Aussois, France. 2012
Poster de conférence hal-02805606v1