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Estradiol promotes functional responses in inflammatory and steady-state dendritic cells through differential requirement for activation function-1 of estrogen receptor α.

Cyril Seillet , Nelly Rouquié , Eliane Foulon , Victorine Douin-Echinard , Andrée Krust , et al.
Journal of Immunology, 2013, 190 (11), pp.5459-70. ⟨10.4049/jimmunol.1203312⟩
Article dans une revue inserm-00852281v1

Androgens are key regulators in allergic asthma

Sophie Laffont
Revue francaise d'allergologie, 2022, 17ème Congrès Francophone d’Allergologie, 62 (3), pp.261. ⟨10.1016/j.reval.2022.02.004⟩
Article dans une revue hal-03987640v1
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Estrogen receptor alpha, but not beta, is required for optimal dendritic cell differentiation and [corrected] CD40-induced cytokine production.

Victorine Douin-Echinard , Sophie Laffont , Cyril Seillet , Laurent Delpy , Andree Krust , et al.
Journal of Immunology, 2008, 180 (6), pp.3661-9
Article dans une revue inserm-00312757v1

Biais de sexe dans l’asthme allergique

Eve Blanquart , Sophie Laffont , Jean-Charles Guéry
Medecine/Sciences, 2018
Chapitre d'ouvrage hal-02378928v1

CD49d/CD29‐integrin controls the accumulation of plasmacytoid dendritic cells into the CNS during neuroinflammation

Arnaud Garnier , Sophie Laffont , Laure Garnier , Elisa Kaba , Urban Deutsch , et al.
European Journal of Immunology, 2019, 49 (11), pp.2030-2043. ⟨10.1002/eji.201948086⟩
Article dans une revue hal-02372827v1

Endogenous estrogens, through estrogen receptor α, constrain autoimmune inflammation in female mice by limiting CD4+ T-cell homing into the CNS.

Karine Lélu , Laurent Delpy , Virginie Robert , Eliane Foulon , Sophie Laffont , et al.
European Journal of Immunology, 2010, 40 (12), pp.3489-98. ⟨10.1002/eji.201040678⟩
Article dans une revue hal-00697795v1

Deconstructing the sex bias in allergy and autoimmunity

Sophie Laffont , Jean-Charles Guéry
Advances in Immunology, 142 (chap 2), Elsevier, pp.35-64, 2019, ⟨10.1016/bs.ai.2019.04.001⟩
Chapitre d'ouvrage hal-02378906v1

T-lymphocyte-derived enkephalins reduce Th1/Th17 colitis and associated pain in mice

Lilian Basso , Laure Garnier , Arnaud Bessac , Jérôme Boué , Catherine Blanpied , et al.
Journal of Gastroenterology, 2018, 53 (2), pp.215-226. ⟨10.1007/s00535-017-1341-2⟩
Article dans une revue hal-01604709v1
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Natural killer cells recruited into lymph nodes inhibit alloreactive T-cell activation through perforin-mediated killing of donor allogeneic dendritic cells.

Sophie Laffont , Cyril Seillet , John Ortaldo , Jérôme D. Coudert , Jean-Charles Guéry
Blood, 2008, 112 (3), pp.661-71. ⟨10.1182/blood-2007-10-120089⟩
Article dans une revue inserm-00306011v1

First experience of hepatic radioembolization using microspheres labelled with yttrium-90 (TheraSphere): practical aspects concerning its implementation.

Etienne Garin , Yan Rolland , Eveline Boucher , Valérie Ardisson , Sophie Laffont , et al.
European Journal of Nuclear Medicine, 2010, 37 (3), pp.453-61. ⟨10.1007/s00259-009-1279-6⟩
Article dans une revue istex hal-00742174v1
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Utility of Quantitative Tc-MAA SPECT/CT for yttrium-Labelled Microsphere Treatment Planning: Calculating Vascularized Hepatic Volume and Dosimetric Approach.

Etienne Garin , Yan Rolland , Laurence Lenoir , Marc Pracht , Habiba Mesbah , et al.
International Journal of Molecular Medicine, 2011, 2011, pp.398051. ⟨10.1155/2011/398051⟩
Article dans une revue hal-00739649v1

Dosimetry based on 99mTc-macroaggregated albumin SPECT/CT accurately predicts tumor response and survival in hepatocellular carcinoma patients treated with 90Y-loaded glass microspheres: preliminary results.

Etienne Garin , Laurence Lenoir , Yan Rolland , Julien Edeline , Habiba Mesbah , et al.
Journal of Nuclear Medicine, 2012, 53 (2), pp.255-63. ⟨10.2967/jnumed.111.094235⟩
Article dans une revue hal-00866987v1
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Targeting androgen signaling in ILC2s protects from IL-33–driven lung inflammation, independently of KLRG1

Eve Blanquart , Audrey Mandonnet , Marion Mars , Claire Cenac , Nina Anesi , et al.
Journal of Allergy and Clinical Immunology, 2022, 149 (1), pp.237-251.e12. ⟨10.1016/j.jaci.2021.04.029⟩
Article dans une revue hal-03411390v1

Estrogen receptor α signaling in T lymphocytes is required for estradiol-mediated inhibition of Th1 and Th17 cell differentiation and protection against experimental autoimmune encephalomyelitis.

Karine Lélu , Sophie Laffont , Laurent Delpy , Pierre-Emmanuel Paulet , Therese Périnat , et al.
Journal of Immunology, 2011, 187 (5), pp.2386-93. ⟨10.4049/jimmunol.1101578⟩
Article dans une revue hal-00697793v1

Clinical feasibility of fast 3-dimensional dosimetry of the liver for treatment planning of hepatocellular carcinoma with 90Y-microspheres.

Arnaud Dieudonné , Etienne Garin , Sophie Laffont , Yan Rolland , Rachida Lebtahi , et al.
Journal of Nuclear Medicine, 2011, 52 (12), pp.1930-7. ⟨10.2967/jnumed.111.095232⟩
Article dans une revue hal-00739517v1

Clinical feasibility of fast 3-dimensional dosimetry of the liver for treatment planning of hepatocellular carcinoma with 90y-microspheres.

Arnaud Dieudonné , Etienne Garin , Sophie Laffont , Yan Rolland , Rachida Lebtahi , et al.
Journal of Nuclear Medicine, 2011, 52, pp.1930-37
Article dans une revue hal-00673449v1

Effectiveness of quantitative MAA SPECT/CT for the definition of vascularized hepatic volume and dosimetric approach: phantom validation and clinical preliminary results in patients with complex hepatic vascularization treated with yttrium-90-labeled microspheres.

Etienne Garin , Laurence Lenoir , Yan Rolland , Sophie Laffont , Marc Pracht , et al.
Nuclear Medicine Communications, 2011, 32 (12), pp.1245-55. ⟨10.1097/MNM.0b013e32834a716b⟩
Article dans une revue hal-00739618v1

Personalized Dosimetry with Intensification Using 90Y-Loaded Glass Microsphere Radioembolization Induces Prolonged Overall Survival in Hepatocellular Carcinoma Patients with Portal Vein Thrombosis.

Etienne Garin , Yan Rolland , Julien Edeline , Nicolas Icard , Laurence Lenoir , et al.
Journal of Nuclear Medicine, 2015, 56 (3), pp.339-46. ⟨10.2967/jnumed.114.145177⟩
Article dans une revue hal-01128116v1

Clinical feasibility of 3D Dosimetry g Voxel S-values or the treament of hepatocellular carcinoma with Yttrium 90 microspheres

Arnaud Dieudonné , Etienne Garin , Sophie Laffont , Yan Rolland , Rachida Lebtahi , et al.
Annual Congress of the EANM, 2011, Birmingham, United Kingdom. pp.1930-7
Communication dans un congrès hal-00673865v1

Reduction of β-radiation exposure during preparation of 188Re-labelled Lipiodol for hepatocellular carcinoma treatment.

Nicolas Lepareur , Sophie Laffont , Valérie Ardisson , Nicolas Noiret , Etienne Garin
Nuclear Medicine Communications, 2012, 33 (2), pp.205-8. ⟨10.1097/MNM.0b013e32834e7580⟩
Article dans une revue hal-00867028v1

The Influence of Sex Hormones and X Chromosome in Immune Responses

Nina Anesi , Charles-Henry Miquel , Sophie Laffont , Jean‐charles Guéry
Sabra L. Klein; Craig W. Roberts. Sex and Gender Differences in Infection and Treatments for Infectious Diseases, 441, Springer Cham, p. 21-59, 2023, Current Topics in Microbiology and Immunology, 978-3-031-35139-6. ⟨10.1007/978-3-031-35139-6_2⟩
Chapitre d'ouvrage hal-04220181v1

The TLR-mediated response of plasmacytoid dendritic cells is positively regulated by estradiol in vivo through cell-intrinsic estrogen receptor α signaling.

Cyril Seillet , Sophie Laffont , Florence Trémollières , Nelly Rouquié , Claude Ribot , et al.
Blood, 2012, 119 (2), pp.454-64. ⟨10.1182/blood-2011-08-371831⟩
Article dans une revue inserm-00726899v1

CD8+ T-cell-mediated killing of donor dendritic cells prevents alloreactive T helper type-2 responses in vivo.

Sophie Laffont , Jérôme D Coudert , Lucile Garidou , Laurent Delpy , Aurélie Wiedemann , et al.
Blood, 2006, 108 (7), pp.2257-64. ⟨10.1182/blood-2005-10-4059⟩
Article dans une revue hal-00458864v1
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Sex hormone regulation of innate lymphoid cells

Eve Blanquart , Sophie Laffont , Jean-Charles Guéry
Biomedical journal, 2020, 44 (2), pp.144-156. ⟨10.1016/j.bj.2020.11.007⟩
Article dans une revue hal-03153831v1

Estrogen Signaling in Bystander Foxp3 neg CD4 + T Cells Suppresses Cognate Th17 Differentiation in Trans and Protects from Central Nervous System Autoimmunity

Laure Garnier , Sophie Laffont , Karine Lélu , Nir Yogev , Ari Waisman , et al.
Journal of Immunology, 2018, 201 (11), pp.3218-3228. ⟨10.4049/jimmunol.1800417⟩
Article dans une revue hal-02378915v1
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High impact of macroaggregated albumin-based tumour dose on response and overall survival in hepatocellular carcinoma patients treated with (90) Y-loaded glass microsphere radioembolization

Etienne Garin , Yan Rolland , Marc Pracht , Samuel Le Sourd , Sophie Laffont , et al.
Liver International, 2017, 37 (1), pp.101-110. ⟨10.1111/liv.13220⟩
Article dans une revue hal-01447063v1
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Différences liées au sexe dans l’asthme allergique : rôle des androgènes sur la biologie des cellules lymphoïdes innées de groupe 2

S. Laffont
Revue francaise d'allergologie, 2020, 60, pp.270 - 271. ⟨10.1016/j.reval.2020.02.043⟩
Article dans une revue hal-03490977v1

Clinicopathologic and Molecular Features of a Series of 41 Biphenotypic Sinonasal Sarcomas Expanding Their Molecular Spectrum

Francois Le Loarer , Sophie Laffont , Tom Lesluyes , Franck Tirode , Cristina Antonescu , et al.
American Journal of Surgical Pathology, 2019, 43 (6), pp.747-754. ⟨10.1097/PAS.0000000000001238⟩
Article dans une revue inserm-02440616v1
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TLR7 dosage polymorphism shapes interferogenesis and HIV-1 acute viremia in women

Pascal Azar , José E Mejía , Claire Cénac , Arnoo Shaiykova , Ali Youness , et al.
JCI Insight, 2020, 5 (12), pp.e136047. ⟨10.1172/jci.insight.136047⟩
Article dans une revue pasteur-02864900v1
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Androgen signaling negatively controls group 2 innate lymphoid cells

Sophie Laffont , Eve Blanquart , Magali Savignac , Claire Cénac , Gilles Laverny , et al.
Journal of Experimental Medicine, 2017, 214 (6), pp.1581-1592. ⟨10.1084/jem.20161807⟩
Article dans une revue hal-03551225v1