Skip to Main content
Number of documents


Solène Desmée - Associate professor - PhD in Biostatistics

Solène Desmée is an Associate Professor in biostatistics. She teaches mathematics and biostatistics at the University Technology Institute of Tours (France) and she is a researcher at SPHERE unit since 2017. She received her PhD in biostatistics from University Paris 7 in 2016. Her research mainly focuses on the development of statistical methods for modelling of longitudinal and survival data in particular using nonlinear joint models in the field of oncology. She also takes part to the QUARTET project on methods to analyze time-to-event outcomes in cluster randomized trials and to provide appropriate measures of clustering.


Jérémie Guedj   

Journal articles4 documents

  • Marion Kerioui, Francois Mercier, Julie Bertrand, Coralie Tardivon, René Bruno, et al.. Bayesian inference using Hamiltonian Monte‐Carlo algorithm for nonlinear joint modeling in the context of cancer immunotherapy. Statistics in Medicine, Wiley-Blackwell, 2020, 39 (30), pp.4853-4868. ⟨10.1002/sim.8756⟩. ⟨hal-03107209⟩
  • Francois Mercier, Marion Kerioui, Solène Desmée, Jeremie Guedj, Oliver Krieter, et al.. Longitudinal analysis of organ-specific tumor lesion sizes in metastatic colorectal cancer patients receiving first line standard chemotherapy in combination with anti-angiogenic treatment. Journal of Pharmacokinetics and Pharmacodynamics, Springer Verlag, 2020, 47 (6), pp.613-625. ⟨10.1007/s10928-020-09714-z⟩. ⟨hal-03184393⟩
  • Solène Desmée, France Mentré, Christine Veyrat-Follet, Bernard Sébastien, Jeremie Guedj. Using the SAEM algorithm for mechanistic joint models characterizing the relationship between nonlinear PSA kinetics and survival in prostate cancer patients. Biometrics, Wiley, 2016, 73 (1), pp.305-312. ⟨10.1111/biom.12537⟩. ⟨inserm-01340693⟩
  • Solène Desmée, France Mentré, Christine Veyrat-Follet, Jérémie Guedj. Nonlinear Mixed-Effect Models for Prostate-Specific Antigen Kinetics and Link with Survival in the Context of Metastatic Prostate Cancer: a Comparison by Simulation of Two-Stage and Joint Approaches. AAPS Journal, American Association of Pharmaceutical Scientists, 2015, pp.1550-7416. ⟨10.1208/s12248-015-9745-5⟩. ⟨inserm-01130444⟩