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Co-exposure of pharmaceuticals and environmental pollutants aggravates disruption of androgen production in human fetal testes.

Pierre Gaudriault , Séverine Mazaud-Guittot , Vincent Lavoue , I. Coiffec , Nathalie Dejucq-Rainsford , et al.
19th European Testis workshop, Jun 2016, Saint-Malo, France
Poster de conférence hal-02439377v1
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EDC IMPACT: Is exposure during pregnancy to acetaminophen/paracetamol disrupting female reproductive development?

Frederic Schrøder Arendrup , Séverine Mazaud-Guittot , Bernard Jégou , David Møbjerg Kristensen
Endocrine Connections, 2018, 7 (1), pp.149-158. ⟨10.1530/EC-17-0298⟩
Article dans une revue hal-01711038v1

Analgesic use - prevalence, biomonitoring and endocrine and reproductive effects

David M. Kristensen , Séverine Mazaud-Guittot , Pierre Gaudriault , Laurianne Lesné , Tania Serrano , et al.
Nature Reviews Endocrinology, 2016, 12 (7), pp.381--393. ⟨10.1038/nrendo.2016.55⟩
Article dans une revue hal-01359566v1

GATA4 autoregulates its own expression in mouse gonadal cells via its distal 1b promoter.

Séverine Mazaud-Guittot , Bruno Prud'Homme , Marie France Bouchard , Francis Bergeron , Caroline Daems , et al.
Biology of Reproduction, 2014, 90 (2), pp.25. ⟨10.1095/biolreprod.113.113290⟩
Article dans une revue hal-01010626v1

Characterization of the effects of the steroidogenesis inhibitor Ketoconazole on the human fetal ovary

P. Lelandais , L. L. Lecante , Christele Desdoits-Lethimonier , S. Connan-Perrot , M. Toupin , et al.
Toxicology Letters, 2021, 350, pp.S174-S174. ⟨10.1016/S0378-4274(21)00652-4⟩
Article dans une revue hal-03439260v1
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Parallel assessment of the effects of bisphenol A and several of its analogs on the adult human testis

Christèle Desdoits-Lethimonier , Lauriane Lesné , Pierre Gaudriault , Daniel Zalko , Jean-Philippe Antignac , et al.
Human Reproduction, 2017, 32 (7), pp.1465--1473. ⟨10.1093/humrep/dex093⟩
Article dans une revue hal-01578582v1
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Integrated metabolomic, lipidomic and steroidomic profiling for revealing signatures and markers of effect induced by bisphenols exposure on human testicular function

Anne-Lise Royer , Yann Guitton , Christele Desdoits-Lethimonier , Séverine Mazaud-Guittot , Hector Gallart-Ayala , et al.
Journées scientifiques RFMF 2016, May 2016, Montpellier, France
Poster de conférence hal-04259825v1

TOXsIgN – un espace de dépôt publique dédié aux signatures toxicologiques

Thomas Alain Darde , Pierre Gaudriault , Rémi Béranger , Lancien Clément , Annaelle Caillarec-Joly , et al.
10 ans PNREST, ANSES, Nov 2016, Paris, France
Poster de conférence hal-02445079v1
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Ibuprofen is deleterious for the development of first trimester human fetal ovary ex vivo

S. Leverrier-Penna , R.T. Mitchell , Emmanuelle Becker , L. Lecante , M. Ben Maamar , et al.
Human Reproduction, 2018, 33 (3), pp.482-493. ⟨10.1093/humrep/dex383⟩
Article dans une revue hal-01739999v1

Paracetamol effects on the human fetal ovary

L. L. Lecante , S. Leverrier-Penna , Antoine D. Rolland , Séverine Mazaud-Guittot
7ème journée de l’UFR de Pharmacie, Jan 2017, Rennes, France
Poster de conférence hal-02439320v1

Current methods to assess chemical contaminant mixture effects – Ex vivo organ culture.

Séverine Mazaud-Guittot
Workshop Société de Pharmacologie Toxicologie Cellulaire (SPTC) / PRINCEPS «Current approaches to assess chemical contaminant mixture effects and regulatory implications », Jun 2015, Paris, France
Communication dans un congrès hal-02439111v1

Mixtures of endocrine disruptors and the fetal human testis.

Pierre Gaudriault , Séverine Mazaud-Guittot , Vincent Lavoue , I. Coiffec , Andreas Kortenkamp , et al.
8th Copenhaguen Workshop on Endocrine Disrupters, May 2015, Copenhagen, Denmark
Poster de conférence hal-02439941v1
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Anatomic and functional mapping of human uterine innervation

Marion Pinsard , Nicolas Mouchet , Ludivine Dion , Thomas Bessede , Martin Bertrand , et al.
Fertility and Sterility, 2022, 117 (6), pp.1279-1288. ⟨10.1016/j.fertnstert.2022.02.013⟩
Article dans une revue hal-03631207v1

Excess type I interferon signaling in the mouse seminiferous tubules leads to germ cell loss and sterility.

Anne-Pascale Satie , Severine Mazaud-Guittot , Isabelle Seif , Dominique Mahé , Zhiguo He , et al.
Journal of Biological Chemistry, 2011, 286 (26), pp.23280-95. ⟨10.1074/jbc.M111.229120⟩
Article dans une revue hal-00682893v1

Dynamics of the transcriptional landscape during human fetal testis development.

Estelle Lecluze , Antoine D. Rolland , Millissia Ben Maamar , I. Coiffec , P. Filis , et al.
19th European Testis workshop, Jun 2016, Saint-Malo, France
Poster de conférence hal-02439398v1
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Loss of tight junction integrity abolishes the epithelial phenotype: the case of Claudin11deficiency in testis.

Séverine Mazaud-Guittot , Emmanuelle Meugnier , Sandra Pesenti , X. Wu , Hubert Vidal , et al.
Biology of Reproduction, 2010, 82 (1), pp.202-13. ⟨10.1095/biolreprod.109.078907⟩
Article dans une revue inserm-01848512v1

P08-11: Characterisation of the effects of Ketoconazole on the human fetal adrenal

L. L. Lecante , P. Vazakidou , P. Lelandais , P. Liu , M. van Duursen , et al.
57th Congress of the European Societies of Toxicology (EUROTOX 2023): TOXICOLOGY - MULTIDISCIPLINARY SCIENCE LEADING TO SAFER AND SUSTAINABLE LIFE, Sep 2023, Ljubljana, Slovenia. pp.S125-S126, ⟨10.1016/s0378-4274(23)00561-1⟩
Communication dans un congrès hal-04285079v1

Paracetamol (acetaminophen) may interfere with the human fetal ovary development in an ex vivo model

L. L. Lecante , S. Leverrier-Penna , Vincent Lavoue , Antoine D. Rolland , Séverine Mazaud-Guittot
Eurotox, Sep 2018, Brussels, Belgium
Poster de conférence hal-02439258v1
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Safeguarding Female Reproductive Health Against Endocrine Disrupting Chemicals-The FREIA Project

Majorie B. M. van Duursen , Julie Boberg , Sofie Christiansen , Lisa Connolly , Pauliina Damdimopoulou , et al.
International Journal of Molecular Sciences, 2020, 21 (9), pp.3215. ⟨10.3390/ijms21093215⟩
Article dans une revue hal-02881471v1

Deregulation of anti-Mullerian hormone/BMP and transforming growth factor-{beta} pathways in Leydig cell lesions developed in male heterozygous multiple endocrine Neoplasia type 1 mutant mice

Nader Hussein , Jieli Lu , Huguette Casse , Sandra Fontanière , Anne-Marie Morera , et al.
Endocrine-Related Cancer, 2008, 15 (1), pp. 217-27. ⟨10.1677/ERC-06-0046⟩
Article dans une revue hal-00671020v1

In vivo regulation of the Gata4 gene promoter during gonadal development and in vitro characterization in gonadal cell lines

Séverine Mazaud-Guittot , Amélie Tétu , David W. Silversides , Robert S. Viger
4th international symposium on vertebrate sex determination, Apr 2006, Hawaii, United States
Communication dans un congrès hal-00697267v1

Toxicité fœtale de l’ibuprofène et du paracétamol sur le développement rénal : étude sur culture organotypique de reins fœtaux humains.

Alain Michel , S. Leverrier-Penna , Emmanuelle Becker , Nathalie Dejucq-Rainsford , Cécile Vigneau , et al.
Deuxième congrès de la Société francophone de néphrologie dialyse et transplantation (SFNDT), Oct 2017, Nice, France
Poster de conférence hal-02439300v1

Paracetamol effects on the human fetal ovary

L. L. Lecante , S. Leverrier-Penna , Antoine D. Rolland , Séverine Mazaud-Guittot
Journée Jeunes Chercheurs de l'Irset, Jan 2018, Rennes, France
Poster de conférence hal-02439274v1

A roadmap for the Human Developmental Cell Atlas

Muzlifah Haniffa , Deanne Taylor , Sten Linnarsson , Bruce Aronow , Gary Bader , et al.
Nature, 2021, 597 (7875), pp.196-205. ⟨10.1038/s41586-021-03620-1⟩
Article dans une revue hal-03365045v1
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Maternal, foetal and child consequences of immunosuppressive drugs during pregnancy in women with organ transplant: a review

Hugoline Boulay , Séverine Mazaud-Guittot , Jeanne Supervielle , Jonathan Maurice M Chemouny , Virginie Dardier , et al.
Clinical Kidney Journal, 2021, 14 (8), pp.1871-1878. ⟨10.1093/ckj/sfab049⟩
Article dans une revue hal-03355311v1
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Functional Assessment of a New PBX1 Variant in a 46,XY Fetus with Severe Syndromic Difference of Sexual Development through CRISPR-Cas9 Gene Editing

Laura Mary , Delphine Leclerc , Audrey Labalme , Pascale Bellaud , Séverine Mazaud-Guittot , et al.
Genes, 2023, 14 (2), pp.273. ⟨10.3390/genes14020273⟩
Article dans une revue hal-04016275v1

Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling

Patrick Callier , Pierre Calvel , Armine Matevossian , Periklis Makrythanasis , Pascal Bernard , et al.
PLoS Genetics, 2014, 10 (5), pp.e1004340. ⟨10.1371/journal.pgen.1004340⟩
Article dans une revue hal-01063929v1

A tridimensional atlas of the developing human head

Raphael Blain , Gérard Couly , Eimad Shotar , Joséphine Blévinal , Maryne Toupin , et al.
Article dans une revue hal-04341975v1

Aniline is rapidly converted into paracetamol impairing male reproductive development

Jacob Bak Holm , Clémentine Chalmey , Hendrik Modick , Lars Skovgaard Jensen , Georg Dierkes , et al.
Toxicological Sciences, 2015, 148 (1), pp.288-298. ⟨10.1093/toxsci/kfv179⟩
Article dans une revue hal-01187305v1

Dissecting the phthalate-induced Sertoli cell injury: the fragile balance of proteases and their inhibitors.

Séverine Mazaud-Guittot
Biology of Reproduction, 2011, 85 (6), pp.1091-3. ⟨10.1095/biolreprod.111.095976⟩
Article dans une revue hal-00682840v1