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Identification of a trafficking motif involved in the stabilization and polarization of P2X receptors.

 Séverine Chaumont-Dubel , Lin-Hua Jiang , Aubin Penna , R Alan North , A. Baranski
Journal of Biological Chemistry, 2004, 279 (28), pp.29628-38. ⟨10.1074/jbc.M403940200⟩
Article dans une revue inserm-00320759v1
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Amelioration of Tau pathology and memory deficits by targeting 5-HT7 receptor

 Josephine Labus , Kian-Fritz Röhrs , Jana Ackmann , Hristo Varbanov , Franziska Müller , et al.
Progress in Neurobiology, 2021, 197, pp.101900. ⟨10.1016/j.pneurobio.2020.101900⟩
Article dans une revue hal-02940990v1

Novel non-sulfonamide 5-HT 6 receptor partial inverse agonist in a group of imidazo[4,5- b ]pyridines with cognition enhancing properties

 David Vanda , Miroslav Soural , Vittorio Canale , Séverine Chaumont-Dubel , Grzegorz Satała , et al.
European Journal of Medicinal Chemistry, 2018, 144, pp.716-729. ⟨10.1016/j.ejmech.2017.12.053⟩
Article dans une revue hal-02366387v1
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Novel 1H-Pyrrolo[3,2-c]quinoline Based 5-HT6 Receptor Antagonists with Potential Application for the Treatment of Cognitive Disorders Associated with Alzheimer's Disease

 Katarzyna Grychowska , Grzegorz Satala , Tomasz Kos , Anna Partyka , Evelina Colacino , et al.
ACS Chemical Neuroscience, 2016, 7 (7), pp.972--83. ⟨10.1021/acschemneuro.6b00090⟩
Article dans une revue hal-01941175v1
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International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function

 Nicholas M Barnes , Gerard P Ahern , Carine Becamel , Joël Bockaert , Michael Camilleri , et al.
Pharmacological Reviews, 2020, 73 (1), pp.310-520. ⟨10.1124/pr.118.015552⟩
Article dans une revue hal-03099832v1
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The 5-HT6 receptor interactome: New insight in receptor signaling and its impact on brain physiology and pathologies

 Séverine Chaumont-Dubel , Vincent Dupuy , Joël Bockaert , Carine Becamel , Philippe Marin
Neuropharmacology, 2019, 172, pp.107839. ⟨10.1016/j.neuropharm.2019.107839⟩
Article dans une revue hal-02364282v1
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2-Phenyl-1 H -pyrrole-3-carboxamide as a New Scaffold for Developing 5-HT 6 Receptor Inverse Agonists with Cognition-Enhancing Activity

 Marcin Drop , Vittorio Canale , Séverine Chaumont-Dubel , Rafał Kurczab , Grzegorz Satała , et al.
ACS Chemical Neuroscience, 2021, 12 (7), pp.1228-1240. ⟨10.1021/acschemneuro.1c00061⟩
Article dans une revue hal-03192567v1
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Impact of the Substitution Pattern at the Basic Center and Geometry of the Amine Fragment on 5-HT6 and D3R Affinity in the 1H-pyrrolo[3,2-c]quinoline Series

 Katarzyna Grychowska , Wojciech Pietruś , Ludmiła Kulawik , Ophélie Bento , Grzegorz Satała , et al.
Molecules, 2023, 28, pp.1096. ⟨10.3390/molecules28031096⟩
Article dans une revue hal-03956220v1
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A dual-acting 5-HT 6 receptor inverse agonist/MAO-B inhibitor displays glioprotective and pro-cognitive properties

 Vittorio Canale , Katarzyna Grychowska , Rafał Kurczab , Mateusz Ryng , Abdul Raheem Keeri , et al.
European Journal of Medicinal Chemistry, 2020, 208, pp.112765. ⟨10.1016/j.ejmech.2020.112765⟩
Article dans une revue hal-03029988v1
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A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility

 Shu-Hsien Sheu , Srigokul Upadhyayula , Vincent Dupuy , Song Pang , Fei Deng , et al.
Cell, 2022, 185 (18), pp.3390-3407. ⟨10.1016/j.cell.2022.07.026⟩
Article dans une revue hal-03796396v1
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Classification and Signaling Characteristics of 5-HT Receptors: Towards the Concept of 5-HT Receptosomes

 Philippe Marin , Carine Becamel , Séverine Chaumont-Dubel , Franck Vandermoere , Joël Bockaert , et al.
Handbook of Behavioral Neuroscience, 31 (Chapter 5), pp.91-120, 2020, Handbook of Behavioral Neurobiology of Serotonin, ⟨10.1016/B978-0-444-64125-0.00005-0⟩
Chapitre d'ouvrage hal-02491823v1

Physical interaction between neurofibromin and serotonin 5-HT 6 receptor promotes receptor constitutive activity

 Wissem Deraredj Nadim , Séverine Chaumont-Dubel , Fahima Madouri , Laetitia Cobret , Marie-Ludivine de Tauzia , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (43), pp.12310 - 12315. ⟨10.1073/pnas.1600914113⟩
Article dans une revue hal-01407899v1
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Superiority of the Triple-Acting 5-HT 6 R/5-HT 3 R Antagonist and MAO-B Reversible Inhibitor PZ-1922 over 5-HT 6 R Antagonist Intepirdine in Alleviation of Cognitive Deficits in Rats

 Katarzyna Grychowska , Uriel López-Sánchez , Mathieu Vitalis , Geoffrey Canet , Grzegorz Satała , et al.
Journal of Medicinal Chemistry, 2023, 66 (21), pp.14928-14947. ⟨10.1021/acs.jmedchem.3c01482⟩
Article dans une revue hal-04235140v1

Agonist-dependent Endocytosis of γ-Aminobutyric Acid Type A (GABAA) Receptors Revealed by a γ2(R43Q) Epilepsy Mutation.

 Severine Chaumont , Caroline André , David Perrais , Eric Boué-Grabot , Antoine Taly , et al.
Journal of Biological Chemistry, 2013, 288 (39), pp.28254-28265. ⟨10.1074/jbc.M113.470807⟩
Article dans une revue hal-01146637v1
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Dual 5-HT 6 and D 3 Receptor Antagonists in a Group of 1 H -Pyrrolo[3,2- c ]quinolines with Neuroprotective and Procognitive Activity

 Katarzyna Grychowska , Séverine Chaumont-Dubel , Rafał Kurczab , Paulina Koczurkiewicz , Caroline Deville , et al.
ACS Chemical Neuroscience, 2019, 10 (7), pp.3183-3196. ⟨10.1021/acschemneuro.8b00618⟩
Article dans une revue hal-02364291v1
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Neuropathic pain-alleviating activity of novel 5-HT6 receptor inverse agonists derived from 2-aryl-1H-pyrrole-3-carboxamide

 Marcin Drop , Florian Jacquot , Vittorio Canale , Séverine Chaumont-Dubel , Maria Walczak , et al.
Bioorganic Chemistry, 2021, 115, pp.105218. ⟨10.1016/j.bioorg.2021.105218⟩
Article dans une revue hal-03324439v1
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The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication

 Amos Fumagalli , Joyce Heuninck , Anne Pizzoccaro , Enora Moutin , Joyce Koenen , et al.
Nature Communications, 2020, 11 (1), pp.4855. ⟨10.1038/s41467-020-18634-y⟩
Article dans une revue hal-02952514v1
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The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism

 M. Jacobshagen , M. Niquille , Séverine Chaumont-Dubel , Philippe Marin , A. Dayer
Development (Cambridge, England), 2014, 141 (17), pp.3370--7. ⟨10.1242/dev.108043⟩
Article dans une revue hal-01950135v1
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Impact of 5-HT6 Receptor Subcellular Localization on Its Signaling and Its Pathophysiological Roles

 Séverine Chaumont-Dubel , Sonya Galant , Matthieu Prieur , Tristan Bouschet , Joël Bockaert , et al.
Cells, 2023, 12 (3), pp.426. ⟨10.3390/cells12030426⟩
Article dans une revue hal-04236957v1
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Early 5‐ HT 6 receptor blockade prevents symptom onset in a model of adolescent cannabis abuse

 Coralie Berthoux , Al Mahdy Hamieh , Angelina Rogliardo , Emilie Doucet , Camille Coudert , et al.
EMBO Molecular Medicine, 2020, 12 (5), pp.e10605. ⟨10.15252/emmm.201910605⟩
Article dans une revue hal-02863763v1
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Dynamic interactions of the 5-HT 6 receptor with protein partners control dendritic tree morphogenesis

 Camille Pujol , Vincent Dupuy , Martial Séveno , Léonie Runtz , Joël Bockaert , et al.
Science Signaling, 2020, 13 (618), pp.eaax9520. ⟨10.1126/scisignal.aax9520⟩
Article dans une revue hal-02485360v1
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Spatiotemporal dynamics of 5-HT6 receptor ciliary localization during mouse brain development

 Vincent Dupuy , Matthieu Prieur , Anne Pizzoccaro , Clara Margarido , Emmanuel Valjent , et al.
Neurobiology of Disease, 2022, 176, pp.105949. ⟨10.1016/j.nbd.2022.105949⟩
Article dans une revue hal-03900095v1
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Novel and atypical pathways for serotonin signaling

 Joël Bockaert , Carine Becamel , Séverine Chaumont-Dubel , Sylvie Claeysen , Franck Vandermoere , et al.
Faculty Reviews, 2021, 10, pp.52. ⟨10.12703/r/10-52⟩
Article dans une revue hal-03256253v1

Cdk5 induces constitutive activation of 5-HT6 receptors to promote neurite growth

 Fanny Duhr , Paul Déléris , F. Raynaud , Martial Séveno , Séverine Morisset-Lopez , et al.
Nature Chemical Biology, 2014, 10 (7), pp.590-597. ⟨10.1038/nchembio.1547⟩
Article dans une revue hal-01178901v1
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Structure-Based Design and Optimization of FPPQ, a Dual-Acting 5-HT 3 and 5-HT 6 Receptor Antagonist with Antipsychotic and Procognitive Properties

 Paweł Zajdel , Katarzyna Grychowska , Szczepan Mogilski , Rafał Kurczab , Grzegorz Satała , et al.
Journal of Medicinal Chemistry, 2021, 64 (18), pp.13279-13298. ⟨10.1021/acs.jmedchem.1c00224⟩
Article dans une revue hal-03357806v1
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mTOR activation by constitutively active serotonin6 receptors as new paradigm in neuropathic pain and its treatment

 Pierre-Yves Martin , Stéphane Doly , Al Mahdy Hamieh , Eric Chapuy , Vittorio Canale , et al.
Progress in Neurobiology, 2020, 193, pp.101846. ⟨10.1016/j.pneurobio.2020.101846⟩
Article dans une revue hal-02906397v1
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1-(Arylsulfonyl-isoindol-2-yl)piperazines as 5-HT6R Antagonists: Mechanochemical Synthesis, In Vitro Pharmacological Properties and Glioprotective Activity

 Vittorio Canale , Wojciech Trybała , Séverine Chaumont-Dubel , Paulina Koczurkiewicz-Adamczyk , Grzegorz Satała , et al.
Biomolecules, 2023, 13 (1), pp.12. ⟨10.3390/biom13010012⟩
Article dans une revue hal-03933561v1
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