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Determinants of Mutation Rate Variation in the Human Germline

Laure Ségurel , Minyoung Wyman , Molly M. Przeworski
Annual Review of Genomics and Human Genetics, 2014, 15 (1), pp.47-70. ⟨10.1146/annurev-genom-031714-125740⟩
Article dans une revue hal-02122468v1
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Mode de vie et diversité génétique dans les populations humaines d'Asie Centrale

Laure Ségurel
Ecologie, Environnement. Université Pierre et Marie Curie - Paris VI, 2010. Français. ⟨NNT : ⟩
Thèse tel-00547600v1

Frequency of the AGT Pro11Leu polymorphism in humans: Does diet matter?

Laure Ségurel , Sophie Lafosse , Evelyne Heyer , Renaud Vitalis
Annals of Human Genetics, 2010, 74 (1), pp.57-64. ⟨10.1111/j.1469-1809.2009.00549.x⟩
Article dans une revue hal-00450027v1

Looking for signatures of sex-specific demography and local adaptation on the X chromosome.

Evelyne Heyer , Laure Segurel
Genome Biology, 2010, 11 (1), pp.203. ⟨10.1186/gb-2010-11-1-203⟩
Article dans une revue hal-00504087v1
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The ABO blood group is a trans-species polymorphism in primates

Laure L. Segurel , Emma E. E. E. Thompson , Timothée T. Flutre , Jessica J. Lovstad , Aarti A. Venkat , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (45), pp.18493 - 18498. ⟨10.1073/pnas.1210603109⟩
Article dans une revue hal-00956369v1
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Elevated rates of horizontal gene transfer in the industrialized human microbiome

Mathieu Groussin , Mathilde Poyet , Ainara Sistiaga , Sean Kearney , Katya Moniz , et al.
Cell, 2021, 184 (8), pp.2053-2067.e18. ⟨10.1016/j.cell.2021.02.052⟩
Article dans une revue hal-03247961v1
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Detection and interpretation of shared genetic influences on 42 human traits

Joseph Pickrell , Tomaz Berisa , Jimmy Liu , Laure Ségurel , Joyce Tung , et al.
Nature Genetics, 2016, 48 (7), pp.709-717. ⟨10.1038/ng.3570⟩
Article dans une revue hal-02122294v1
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Variation in Rural African Gut Microbiota Is Strongly Correlated with Colonization by Entamoeba and Subsistence

Elise R Morton , Joshua Lynch , Alain Froment , Sophie Lafosse , Evelyne Heyer , et al.
PLoS Genetics, 2015, 11 (11), pp.e1005658. ⟨10.1371/journal.pgen.1005658⟩
Article dans une revue hal-02122300v1

Ancestry runs deeper than blood: The evolutionary history of ABO points to cryptic variation of functional importance

Laure L. Segurel , Ziyue Gao , Molly Przeworski
BioEssays, 2013, pp.n/a-n/a. ⟨10.1002/bies.201300030⟩
Article dans une revue hal-02952310v1
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Changes in the Human Gut Microbiota Associated With Colonization by Blastocystis sp. and Entamoeba spp. in Non-Industrialized Populations

Gaël Even , Ana Lokmer , Jules Rodrigues , Christophe Audebert , Eric Viscogliosi , et al.
Frontiers in Cellular and Infection Microbiology, 2021, 11, pp.533528. ⟨10.3389/fcimb.2021.533528⟩
Article dans une revue hal-03369887v1

Sex-specific genetic diversity is shaped by cultural factors in Inner Asian human populations

Nina Marchi , Tatyana Hegay , Philippe Mennecier , Myriam Georges , Romain Laurent , et al.
American Journal of Physical Anthropology, 2017, 162 (4), pp.627-640. ⟨10.1002/ajpa.23151⟩
Article dans une revue hal-02277564v1
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Sex-specific genetic structure and social organization in Central Asia: insights from a multi-locus study.

Laure Ségurel , Begoña Martínez-Cruz , Lluis Quintana-Murci , Patricia Balaresque , Myriam Georges , et al.
PLoS Genetics, 2008, 4 (9), pp.e1000200. ⟨10.1371/journal.pgen.1000200⟩
Article dans une revue hal-00328137v1
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In the heartland of Eurasia: the multilocus genetic landscape of Central Asian populations

Evelyne Heyer , Begoña Martínez-Cruz , Renaud Vitalis , Laure Ségurel , Frédéric Austerlitz , et al.
European Journal of Human Genetics, 2010, ⟨10.1038/ejhg.2010.153⟩
Article dans une revue hal-00574375v1
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The complex binding of PRDM9

Laure Ségurel
Genome Biology, 2013, 14 (4), pp.112. ⟨10.1186/gb-2013-14-4-112⟩
Article dans une revue hal-02952315v1

Lactase persistence in central Asia: phenotype, genotype, and evolution.

Evelyne Heyer , Lionel Brazier , Laure Ségurel , Tatiana Hegay , Frédéric Austerlitz , et al.
Human Biology, 2011, 83 (3), pp.379-92. ⟨10.3378/027.083.0304⟩
Article dans une revue hal-00662711v1
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The human gut microbiome and health inequities

Katherine Amato , Marie-Claire Arrieta , Meghan Azad , Michael Bailey , Josiane Broussard , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (25), pp.e2017947118. ⟨10.1073/pnas.2017947118⟩
Article dans une revue hal-03369892v1
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Close inbreeding and low genetic diversity in Inner Asian human populations despite geographical exogamy

Nina Marchi , Philippe Mennecier , Myriam Georges , Sophie Lafosse , Tatyana Hegay , et al.
Scientific Reports, 2018, 8, pp.9397. ⟨10.1038/s41598-018-27047-3⟩
Article dans une revue hal-01833978v1

Preserving immune diversity through ancient inheritance and admixture

Laure L. Segurel , Lluis Quintana-Murci
Current Opinion in Immunology, 2014, 30, pp.79-84. ⟨10.1016/j.coi.2014.08.002⟩
Article dans une revue hal-02952285v1
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Population designations in biomedical research: limitations and perspectives

Caroline Gombault , Guillaume Grenet , Laure Ségurel , Laurent Duret , François Gueyffier , et al.
HLA: Immune Response Genetics, 2022, ⟨10.1111/tan.14852⟩
Article dans une revue hal-03829218v1
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Detection of Allelic Frequency Differences between the Sexes in Humans: A Signature of Sexually Antagonistic Selection

Elise Lucotte , Romain Laurent , Evelyne Heyer , Laure Ségurel , Bruno Toupance
Genome Biology and Evolution, 2016, 8 (5), pp.1489-1500. ⟨10.1093/gbe/evw090⟩
Article dans une revue hal-02122292v1

TroX: a new method to learn about the genesis of aneuploidy from trisomic products of conception

Amir Kermany , Laure L. Segurel , Tiffany Oliver , Molly Przeworski
Bioinformatics, 2014, 30 (14), pp.2035-2042. ⟨10.1093/bioinformatics/btu159⟩
Article dans une revue hal-02952296v1
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Codiversification of gut microbiota with humans

Taichi Suzuki , J. Liam Fitzstevens , Victor Schmidt , Hagay Enav , Kelsey Huus , et al.
Science, 2022, 377 (6612), pp.1328-1332. ⟨10.1126/science.abm7759⟩
Article dans une revue hal-03796464v1

On the Evolution of Lactase Persistence in Humans

Laure Ségurel , Céline Bon
Annual Review of Genomics and Human Genetics, 2017, 18 (1), pp.297-319. ⟨10.1146/annurev-genom-091416-035340⟩
Article dans une revue hal-02122280v1
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The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations

Sophie Mathieu , Mélanie Touvrey , Laurent Poulet , Sophie Drouillard , Thirumalai Selvi Ulaganathan , et al.
2023
Pré-publication, Document de travail hal-04234776v1
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Microbiome intestinal ancien et problématiques médicales contemporaines

Philippe Charlier , Anaïs Augias , Philippe Sansonetti , Céline Bon , Sean Kennedy , et al.
Autre publication scientifique istex pasteur-02552079v1
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The Case of the Fickle Fingers: How the PRDM9 Zinc Finger Protein Specifies Meiotic Recombination Hotspots in Humans

Laure Ségurel , Ellen Miranda Leffler , Molly M. Przeworski
PLoS Biology, 2011, 9 (12), pp.e1001211. ⟨10.1371/journal.pbio.1001211⟩
Article dans une revue hal-02120804v1
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Revisiting an Old Riddle: What Determines Genetic Diversity Levels within Species?

Ellen Miranda Leffler , Kevin Bullaughey , Daniel R Matute , Wynn Meyer , Laure Ségurel , et al.
PLoS Biology, 2012, 10 (9), pp.e1001388. ⟨10.1371/journal.pbio.1001388⟩
Article dans une revue hal-02952322v1
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Multiple Instances of Ancient Balancing Selection Shared Between Humans and Chimpanzees

E. Leffler , Z. Gao , S. Pfeifer , L. Segurel , A. Auton , et al.
Science, 2013, 339 (6127), pp.1578-1582. ⟨10.1126/science.1234070⟩
Article dans une revue hal-02952319v1

Gut Protozoa: Friends or Foes of the Human Gut Microbiota?

Magali Chabé , Ana Lokmer , Laure Ségurel
Trends in Parasitology, 2017, 33 (12), pp.925-934. ⟨10.1016/j.pt.2017.08.005⟩
Article dans une revue hal-02122273v1
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Microsatellite data show recent demographic expansions in sedentary but not in nomadic human populations in Africa and Eurasia

Carla Aimé , Paul Verdu , Laure L. Segurel , Begoña Martinez-Cruz , Tatyana Hegay , et al.
European Journal of Human Genetics, 2014, 22 (10), pp.1201-1207. ⟨10.1038/ejhg.2014.2⟩
Article dans une revue hal-03114049v1