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A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis.

Michel Becuwe , Neide Vieira , David Lara , Jéssica Gomes-Rezende , Carina Soares-Cunha , et al.
Journal of Cell Biology, 2012, 196 (2), pp.247-59. ⟨10.1083/jcb.201109113⟩
Article dans une revue hal-00665246v1

Characterization of Protein-Protein Interactions: application to the understanding of peroxisome biogenesis.

Sébastien Léon , Ivet Suriapranata , Mingda Yan , Naganand Rayapuram , Amar Patel , et al.
Methods Mol Biol, vol. 389, pp.219-237, 2007
Chapitre d'ouvrage hal-02110183v1

A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting

Zoi Erpapazoglou , Manel Dhaoui , Marina Pantazopoulou , Francesca Giordano , Muriel Mari , et al.
Molecular Biology of the Cell, 2012, 23 (11), pp.2170-2183. ⟨10.1091/mbc.E11-10-0891⟩
Article dans une revue hal-02110263v1

Two Independent Pathways Traffic the Intraperoxisomal Peroxin PpPex8p into Peroxisomes: Mechanism and Evolutionary Implications

Lan Zhang , Sébastien Léon , Suresh Subramani
Molecular Biology of the Cell, 2006, 17 (2), pp.690-699. ⟨10.1091/mbc.E05-08-0758⟩
Article dans une revue hal-02110046v1
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2-deoxyglucose transiently inhibits yeast AMPK signaling and triggers glucose transporter endocytosis, potentiating the drug toxicity

Clotilde Laussel , Véronique Albanèse , Francisco Javier García-Rodríguez , Alberto Ballin , Quentin Defenouillère , et al.
PLoS Genetics, 2022, 18 (8), pp.e1010169. ⟨10.1371/journal.pgen.1010169⟩
Article dans une revue hal-03843255v1
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The α‐arrestin family of ubiquitin ligase adaptors links metabolism with selective endocytosis

Jennifer Kahlhofer , Sébastien Léon , David Teis , Oliver Schmidt
Biology of the Cell, 2021, ⟨10.1111/boc.202000137⟩
Article dans une revue hal-03063758v2

A deubiquitylating complex required for neosynthesis of a yeast mitochondrial ATP synthase subunit.

Sophie Kanga , Delphine Bernard , Anne-Marie Mager-Heckel , Zoi Erpapazoglou , Francesca Mattiroli , et al.
PLoS ONE, 2012, 7 (6), pp.e38071. ⟨10.1371/journal.pone.0038071⟩
Article dans une revue hal-00776438v1

The AtNFS2 gene from Arabidopsis thaliana encodes a NifS-like plastidial cysteine desulphurase

Sébastien Léon , Brigitte Touraine , Jean-Francois J.-F. Briat , Stephane Lobreaux
Biochemical Journal, 2002, 366 (2), pp.557-564. ⟨10.1042/BJ20020322⟩
Article dans une revue hal-02109848v1

Severe osmotic compression triggers a slowdown of intracellular signaling, which can be explained by molecular crowding.

Agnès Miermont , François Waharte , Shiqiong Hu , Megan Nicole Mcclean , Samuel Bottani , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (14), pp.5725-30. ⟨10.1073/pnas.1215367110⟩
Article dans une revue hal-00817393v1
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Cellular toxicity of the metabolic inhibitor 2-deoxyglucose and associated resistance mechanisms

Sébastien Léon , Clotilde Laussel
Biochemical Pharmacology, 2020, 182, pp.114213. ⟨10.1016/j.bcp.2020.114213⟩
Article dans une revue hal-02988693v1
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Ubc13–Mms2 cooperates with a family of RING E3 proteins in budding yeast membrane protein sorting

Christian Renz , Véronique Albanèse , Vera Tröster , Thomas Albert , Olivier Santt , et al.
Journal of Cell Science, 2020, 133 (10), pp.jcs244566. ⟨10.1242/jcs.244566⟩
Article dans une revue hal-02988699v1

Iron-sulphur cluster assembly in plants: distinct NFU proteins in mitochondria and plastids from Arabidopsis thaliana

Sébastien Léon , Brigitte Touraine , Cécile C. Ribot , Jean-Francois Briat , Stéphane Lobreaux
Biochemical Journal, 2003, 371 (3), pp.823 - 830. ⟨10.1042/BJ20021946⟩
Article dans une revue hal-01759716v1

The Saccharomyces cerevisiae vacuolar acid trehalase is targeted at the cell surface for its physiological function.

Susu He , Kerstin Bystricky , Sebastien Leon , Jean Marie François , Jean L Parrou
FEBS Journal, 2009, 276 (19), pp.5432-46. ⟨10.1111/j.1742-4658.2009.07227.x⟩
Article dans une revue hal-00493311v1
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The regulation of HAD-like phosphatases by signaling pathways modulates cellular resistance to the metabolic inhibitor, 2-deoxyglucose

Quentin Defenouillère , Agathe Verraes , Clotilde Laussel , Anne Friedrich , Joseph Schacherer , et al.
Science Signaling, 2019, 12 (597), pp.eaaw8000. ⟨10.1126/scisignal.aaw8000⟩
Article dans une revue hal-03064377v1

Casein kinase 1 controls the activation threshold of an α-arrestin by multisite phosphorylation of the interdomain hinge.

Antonio Herrador , Daniela Livas , Lucía Soletto , Michel Becuwe , Sébastien Léon , et al.
Molecular Biology of the Cell, 2015, 26 (11), pp.2128-38. ⟨10.1091/mbc.E14-11-1552⟩
Article dans une revue hal-01221844v1

Functional patchworking at the plasma membrane

Sébastien Léon , David Teis
EMBO Journal, 2018, 37 (16), pp.e100144. ⟨10.15252/embj.2018100144⟩
Article dans une revue hal-02110293v1
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Studying protein ubiquitylation in yeast

Junie Hovsepian , Michel Becuwe , Oded Kleifeld , Michael Glickman , Sébastien Léon
Proteostasis: Methods and Protocols, pp.117-142, 2016, ⟨10.1007/978-1-4939-3756-1_5⟩
Chapitre d'ouvrage hal-02322657v1
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Complementary a-arrestin-ubiquitin ligase complexes control nutrient transporter endocytosis in response to amino acids

Vasyl Ivashov , Johannes Zimmer , Sinead Schwabl , Jennifer Kahlhofer , Sabine Weys , et al.
Article dans une revue hal-02988704v1

Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms

Elena Kazamia , Robert Sutak , Javier Paz-Yepes , Richard Dorrell , Fabio Rocha Jimenez Vieira , et al.
Science Advances , 2018, 4 (5), pp.eaar4536. ⟨10.1126/sciadv.aar4536⟩
Article dans une revue cea-01886772v1

Integrated control of transporter endocytosis and recycling by the arrestin-related protein Rod1 and the ubiquitin ligase Rsp5.

Michel Becuwe , Sébastien Léon
eLife, 2013, 3, pp.e03307. ⟨10.7554/eLife.03307⟩
Article dans une revue hal-01128412v1
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2-deoxyglucose transiently inhibits yeast AMPK signaling and triggers glucose transporter endocytosis, potentiating the drug toxicity

Clotilde Laussel , Véronique Albanèse , Francisco Javier García-Rodríguez , Alberto Ballin , Quentin Defenouillère , et al.
2022
Pré-publication, Document de travail hal-03865336v1
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Sensitive detection of protein ubiquitylation using a protein-fragment complementation assay

Marie Le Boulch , Audrey Brossard , Gaëlle Le Dez , Sébastien Léon , Gwenaël Rabut
Journal of Cell Science, 2020, 133 (12), pp.jcs240093. ⟨10.1242/jcs.240093⟩
Article dans une revue hal-02635146v1
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The yeast arrestin-related protein Bul1 is a novel actor of glucose-induced endocytosis

Junie Hovsepian , Véronique Albanèse , Michel Becuwe , Vasyl Ivashov , David Teis , et al.
Molecular Biology of the Cell, 2018, 29 (9), pp.1012-1020. ⟨10.1091/mbc.E17-07-0466⟩
Article dans une revue hal-02322681v1
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Multilevel regulation of an α-arrestin by glucose depletion controls hexose transporter endocytosis

Junie Hovsepian , Quentin Defenouillère , Véronique Albanèse , Libuše Váchová , Camille Garcia , et al.
Journal of Cell Biology, 2017, 216 (6), pp.1811-1831. ⟨10.1083/jcb.201610094⟩
Article dans une revue hal-02322597v1

Versatile role of the yeast ubiquitin ligase Rsp5p in intracellular trafficking.

Naima Belgareh-Touzé , Sébastien Léon , Zoi Erpapazoglou , Marta Stawiecka-Mirota , Danièle Urban-Grimal , et al.
Biochemical Society Transactions, 2008, 36 (Pt 5), pp.791-6. ⟨10.1042/BST0360791⟩
Article dans une revue hal-00332641v1

A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis.

Inbal Ziv , Yulia Matiuhin , Donald S Kirkpatrick , Zoi Erpapazoglou , Sebastien Leon , et al.
Molecular and Cellular Proteomics, 2011, 10 (5), pp.M111.009753. ⟨10.1074/mcp.M111.009753⟩
Article dans une revue hal-00605985v1

Ubiquitin-mediated regulation of endocytosis by proteins of the arrestin family.

Michel Becuwe , Antonio Herrador , Rosine Haguenauer-Tsapis , Olivier Vincent , Sébastien Léon
Biochem Res Int, 2012, 2012, pp.242764. ⟨10.1155/2012/242764⟩
Article dans une revue hal-00759425v1

Ear1p and Ssh4p Are New Adaptors of the Ubiquitin Ligase Rsp5p for Cargo Ubiquitylation and Sorting at Multivesicular Bodies.

Sébastien Léon , Zoi Erpapazoglou , Rosine Haguenauer-Tsapis
Molecular Biology of the Cell, 2008, epub ahead of print. ⟨10.1091/mbc.E08-01-0068⟩
Article dans une revue hal-00268036v1

A Conserved Cysteine Residue of Pichia pastoris Pex20p Is Essential for Its Recycling from the Peroxisome to the Cytosol

Sébastien Léon , Suresh Subramani
Journal of Biological Chemistry, 2007, 282 (10), pp.7424-7430. ⟨10.1074/jbc.M611627200⟩
Article dans une revue hal-02110187v1
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Endocytosis and stress: From mechanisms to cellular physiology

Sébastien Léon
Biology of the Cell, 2021, 113 (11), pp.439-440. ⟨10.1111/boc.202100072⟩
Article dans une revue hal-03843268v1