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The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates.

K. Lindmo , A. Brech , K.D Finley , Sebastien Gaumer , Didier Contamine , et al.
Autophagy, 2008, 4, pp.500-506
Article dans une revue hal-00321165v1

02.22 Taking fly for understanding the molecular role of HLA-b27/hβ2m in spondyloarthritis

Nadège Jah , Benjamin Grandon , Aurore Rincheval-Arnold , Isabelle Guénal , Sébastien Gaumer , et al.
37th European Workshop for Rheumatology Research, Mar 2017, Athens, Greece. pp.A17
Communication dans un congrès hal-04444083v1
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Taking Fly for Understanding the Molecular Role of HLAB27/hB2m in Spondyloarthritis

Nadège Jah , Benjamin Grandon , Aurore Rincheval-Arnold , Isabelle Guénal , Sébastien Gaumer , et al.
2016 ACR/ARHP Annual Meeting, Nov 2016, Washigton, D.C., France
Communication dans un congrès hal-04443729v1

Is fruit fly relevant to SpA?

Sébastien Gaumer , Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi , et al.
Eleventh International Congress on Spondyloarthritides, Oct 2018, Gent, Belgium. pp.693
Communication dans un congrès hal-04444000v1
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L'apoptose chez la drosophile : conservation et originalité

Sébastien Gaumer , Isabelle Guenal , Sylvain Brun , Bernard Mignotte
Médecine/Sciences, 2002
Article dans une revue hal-03002807v1
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HLA-B27 alters BMP/TGFβ signalling in Drosophila, revealing putative pathogenic mechanism for spondyloarthritis

Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi , Luiza M Araujo , et al.
Annals of the Rheumatic Diseases, 2019, 78 (12), pp.1653. ⟨10.1136/annrheumdis-2019-215832⟩
Article dans une revue hal-02975533v1
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Screening of suppressors of bax-induced cell death identifies glycerophosphate oxidase-1 as a mediator of debcl-induced apoptosis in Drosophila

Jessie Colin , Julie Garibal , Amandine Clavier , Sébastien Szuplewski , Yanick Risler , et al.
Genes and Cancer, 2015, 6, ⟨10.18632/genesandcancer.68⟩
Article dans une revue hal-02975511v1
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Bcl-2 and Bax mammalian regulators of apoptosis are functional in Drosophila

S Gaumer , I Guenal , S Brun , L Theodore , Bernard Mignotte
Cell Death and Differentiation, 2000, 7, pp.804-814. ⟨10.1038/sj.cdd.4400714⟩
Article dans une revue hal-03034620v2
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Mécanismes de la réponse aux stress cellulaires

Sébastien Gaumer
Organisation et fonctions cellulaires [q-bio.SC]. Université de Versailles Saint-Quentin-en-Yvelines, 2019
HDR tel-04385429v1
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Lessons on SpA pathogenesis from animal models

Maxime Breban , Simon Glatigny , Bilade Cherqaoui , Marie Beaufrère , Marc Lauraine , et al.
Seminars in Immunopathology, 2021, ⟨10.1007/s00281-020-00832-x⟩
Article dans une revue hal-03113204v1
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HLA-B27/hβ2m Drosophila a new model to study HLA-B27 implication in spondyloarthritis

Nadège Jah , Benjamin Grandon , Aurore Rincheval-Arnold , Isabelle Guénal , Sébastien Gaumer , et al.
Tenth International Congress on Spondyloarthritides, Sep 2016, Gent, Belgium. pp.742-743
Communication dans un congrès hal-04443952v1
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Quantification of Ataxin-3 and Ataxin-7 aggregates formed in vivo in Drosophila reveals a threshold of aggregated polyglutamine proteins associated with cellular toxicity

Gerald Vinatier , Jean-Marc Corsi , Bernard Mignotte , Sebastien Gaumer
Biochemical and Biophysical Research Communications, 2015, ⟨10.1016/j.bbrc.2015.07.071⟩
Article dans une revue hal-02975551v1
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The PERK pathway independently triggers apoptosis and a Rac1/Slpr/JNK/Dilp8 signaling favoring tissue homeostasis in a chronic ER stress Drosophila model

Y Demay , J Perochon , S Szuplewski , Bernard Mignotte , S Gaumer
Cell Death and Disease, 2014, 5, pp.e1452. ⟨10.1038/cddis.2014.403⟩
Article dans une revue hal-02977710v1

Bcl-2 and Hsp27 act at different levels to suppress programmed cell death

Isabelle Guenal , Carole Sidoti-de Fraisse , Sebastien Gaumer , Bernard Mignotte
Oncogene, 1997, 15 (3), pp.347-360. ⟨10.1038/sj.onc.1201182⟩
Article dans une revue hal-03036419v1
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zVAD-fmk upregulates caspase-9 cleavage and activity in etoposide-induced cell death of mouse embryonic fibroblasts

Aida Rodríguez-Enfedaque , Elisabeth Delmas , Arnaud Guillaume , Sébastien Gaumer , Bernard Mignotte , et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 2012, 1823, pp.1343 - 1352. ⟨10.1016/j.bbamcr.2012.05.013⟩
Article dans une revue hal-02996979v1

Génétique

Jean-Louis Serre , Sébastien Gaumer , Sophie Netter
Dunod. 2018, Sciences Sup, 978-2-10-076000-8
Ouvrages hal-04492992v1

Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain.

I.P. Nezis , A. Simonsen , A.P Sagona , K. Finley , Sébastien Gaumer , et al.
Cell Biology and Toxicology, 2008, 180, pp.1065-1071
Article dans une revue hal-00321169v1
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The drosophila Bcl-2 family protein Debcl is targeted to the proteasome by the b-TrCP homologue slimb

Jessie Colin , Julie Garibal , Amandine Clavier , Aurore Rincheval-Arnold , Sébastien Gaumer , et al.
Apoptosis, 2014, 19 (10), pp.1444-1456. ⟨10.1007/s10495-014-1034-8⟩
Article dans une revue hal-02977706v1

An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis

A. Boeddrich , Sébastien Gaumer , A. Haacke , N. Tzvetkov , M. Albrecht , et al.
EMBO Journal, 2006, 25(7), pp.1547-1558
Article dans une revue hal-00101273v1

Chronic ER stress response signaling depends on the affected region but not on the source of stress

Jessica Perochon , Benjamin Grandon , Delphine Roche , Christine Wintz , Yohan Demay , et al.
Endoplasmic reticulum 2019, Jun 2019, Paris, France. 2019
Poster de conférence hal-04488695v1

Chronic ER stress response signaling depends on the affected region but not on the source of stress

Jessica Perochon , Benjamin Grandon , Delphine Roche , Christine Wintz , Yohan Demay , et al.
Drosoph’Île de France, Jun 2019, Paris, France
Poster de conférence hal-04488690v1

Le HLA-B27 dérégule la voie de signalisation BMP/TGFbeta, une nouvelle hypothèse pour expliquer sa pathogénicité

Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi , L.M. Araujo , et al.
32ème Congrès Français de Rhumatologie, Dec 2019, Paris, France
Poster de conférence hal-04493012v1
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Mitochondria, Bcl-2 family proteins and apoptosomes: of worms, flies and men

Jessie Colin , Sebastien Gaumer , Isabelle Guenal , Bernard Mignotte
Frontiers in bioscience : a journal and virtual library, 2009, S1 (14), pp.290-300. ⟨10.2741/3517⟩
Article dans une revue hal-00354315v1
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The endoplasmic reticulum unfolded protein response varies depending on the affected region of the tissue but independently from the source of stress

Jessica Perochon , Benjamin Grandon , Delphine Roche , Christine Wintz , Yohan Demay , et al.
Cell Stress and Chaperones, 2019, ⟨10.1007/s12192-019-01009-8⟩
Article dans une revue hal-02975482v1

Control of sigma virus multiplication by the ref(2)P gene of Drosophila melanogaster. An in vivo study of the PB1 domain of Ref(2)P

A. Carre-Mlouka , Sébastien Gaumer , Pascal Gay , Am Petitjean , C. Coulondre , et al.
Genetics, 2007, 176, pp.409-19
Article dans une revue hal-00172699v1

S. Sigma Rhabdoviruses. ENcyclopedia of Virology, 5 volc.

Didier Contamine , Sébastien Gaumer
encylopedia of virology, B.W.J. Mahy and M.H.V.Van Regenmortel, Editors, pp.576-581, 2008
Chapitre d'ouvrage hal-00354310v1

Life span extension by dietary restriction is reduced but not abolished by loss of both SIR2 and HST2 in Podospora anserina.

A. Boivin , Sébastien Gaumer , A. Sainsard
Mechanisms of Ageing and Development, 2008, 129, pp.712-21
Article dans une revue hal-00354223v1