Sébastien FIORUCCI

Documents

Publications

	M2OR: a database of olfactory receptor–odorant pairs for understanding the molecular mechanisms of olfaction Maxence Lalis , Matej Hladiš , Samar Abi Khalil , Loïc Briand , Sébastien Fiorucci Nucleic Acids Research, 2024, 52 (D1), pp.D1370-D1379. ⟨10.1093/nar/gkad886⟩ Article dans une revue hal-04345122v1
	Exploring Dihydroflavonol‐4‐Reductase Reactivity and Selectivity by QM/MM‐MD Simulations Julien Diharce , Emmanuelle Bignon , Sébastien Fiorucci , Serge Antonczak ChemBioChem, 2022, 23 (3), ⟨10.1002/cbic.202100553⟩ Article dans une revue hal-03599132v1
	Reverse chemical ecology in a moth: machine learning on odorant receptors identifies new behaviorally active agonists Gabriela Caballero-Vidal , Cédric Bouysset , Jérémy Gévar , Hayat Mbouzid , Céline Nara Cellular and Molecular Life Sciences, 2021, 78 (19-20), pp.6593-6603. ⟨10.1007/s00018-021-03919-2⟩ Article dans une revue hal-03635144v1
	ProLIF: a library to encode molecular interactions as fingerprints Cédric Bouysset , Sébastien Fiorucci Journal of Cheminformatics, 2021, 13 (1), pp.72. ⟨10.1186/s13321-021-00548-6⟩ Article dans une revue hal-03599131v1
	Functional molecular switches of mammalian G protein-coupled bitter-taste receptors Jérémie Topin , Cédric Bouysset , Jody Pacalon , Yiseul Kim , Meera Rhyu Cellular and Molecular Life Sciences, 2021, 78, pp.7605-7615. ⟨10.1007/s00018-021-03968-7⟩ Article dans une revue hal-02544670v1
	Corrigendum to: More than smell. COVID-19 is associated with severe impairment of smell, taste, and chemesthesis Valentina Parma , Kathrin Ohla , Maria G Veldhuizen , Masha Niv , Christine E. Kelly Chemical Senses, 2021, 46, pp.bjab050. ⟨10.1093/chemse/bjab050⟩ Article dans une revue hal-03525901v1
	Machine learning decodes chemical features to identify novel agonists of a moth odorant receptor Gabriela Caballero-Vidal , Cédric Bouysset , Hubert Grunig , Sébastien Fiorucci , Nicolas Montagné Scientific Reports, 2020, 10 (1), pp.1655. ⟨10.1038/s41598-020-58564-9⟩ Article dans une revue hal-03599128v1
	Novel scaffold of natural compound eliciting sweet taste revealed by machine learning Cédric Bouysset , Christine Belloir , Serge Antonczak , Loïc Briand , Sébastien Fiorucci Food Chemistry, 2020, 324, pp.126864. ⟨10.1016/j.foodchem.2020.126864⟩ Article dans une revue hal-02547525v1
	More than smell. COVID-19 is associated with severe impairment of smell, taste, and chemesthesis Valentina Parma , Kathrin Ohla , Maria G Veldhuizen , Masha Niv , Christine E. Kelly Chemical Senses, 2020, 45 (7), pp.609-622. ⟨10.1093/chemse/bjaa041⟩ Article dans une revue hal-02911030v1
	Metal Ions Activate the Human Taste Receptor TAS2R7 Yi Wang , Amanda Zajac , Weiwei Lei , Carol Christensen , Robert Margolskee Chemical Senses, 2019, 44 (5), pp.339-347. ⟨10.1093/chemse/bjz024⟩ Article dans une revue hal-02545190v1
	Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts Xiaojing Cong , Qian Zheng , Wenwen Ren , Jean-Baptiste Chéron , Sébastien Fiorucci Journal of Biological Chemistry, 2019, 294 (17), pp.6762-6771. ⟨10.1074/jbc.RA118.006483⟩ Article dans une revue hal-02545194v1
	Conserved Residues Control the T1R3-Specific Allosteric Signaling Pathway of the Mammalian Sweet-Taste Receptor Jean-Baptiste Chéron , Amanda Soohoo , Yi Wang , Jérôme Golebiowski , Serge Antonczak Chemical Senses, 2019, 44 (5), pp.303-310. ⟨10.1093/chemse/bjz015⟩ Article dans une revue hal-02545196v1
	Allosteric Modulation Mechanism of the mGluR 5 Transmembrane Domain Xiaojing Cong , Jean-Baptiste Chéron , Jérôme Golebiowski , Serge Antonczak , Sébastien Fiorucci Journal of Chemical Information and Modeling, 2019, ⟨10.1021/acs.jcim.9b00045⟩ Article dans une revue hal-02137256v1
	Agonists of G-Protein-Coupled Odorant Receptors Are Predicted from Chemical Features C. Bushdid , C. de March , Sébastien Fiorucci , H. Matsunami , J. Golebiowski Journal of Physical Chemistry Letters, 2018, 9 (9), pp.2235-2240. ⟨10.1021/acs.jpclett.8b00633⟩ Article dans une revue hal-02545199v1
	Activation Dynamics of the Neurotensin G Protein-Coupled Receptor 1 Xiaojing Cong , Sébastien Fiorucci , Jérôme Golebiowski Journal of Chemical Theory and Computation, 2018, 14 (8), pp.4467-4473. ⟨10.1021/acs.jctc.8b00216⟩ Article dans une revue hal-02545198v1
	The anatomy of mammalian sweet taste receptors Jean-Baptiste Chéron , Jérôme Golebiowski , Serge Antonczak , Sébastien Fiorucci Proteins - Structure, Function and Bioinformatics, 2017, 85 (2), pp.332-341. ⟨10.1002/prot.25228⟩ Article dans une revue hal-02545213v1
	Ces molécules qui éveillent nos papilles Jean-Baptiste Chéron , Jérôme Golebiowski , Serge Antonczak , Loïc Briand , Sébastien Fiorucci L'Actualité Chimique, 2017, 416, pp.11-18 Article dans une revue hal-01575125v1
	Update of the ATTRACT force field for the prediction of protein-protein binding affinity Jean-Baptiste Chéron , Martin Zacharias , Serge Antonczak , Sébastien Fiorucci Journal of Computational Chemistry, 2017, 38 (21), pp.1887-1890. ⟨10.1002/jcc.24836⟩ Article dans une revue hal-02545204v1
	Bornyl-diphosphate synthase from Lavandula angustifolia: A major monoterpene synthase involved in essential oil quality Yolande Despinasse , Sébastien Fiorucci , Serge Antonczak , Sandrine Moja , Aurélie Bony Phytochemistry, 2017, 137, pp.24-33. ⟨10.1016/j.phytochem.2017.01.015⟩ Article dans une revue hal-02545209v1
	Design, synthesis and photophysical studies of styryl-based push–pull fluorophores with remarkable solvatofluorochromism Mauro Safir Filho , Sébastien Fiorucci , Anthony Martin , Rachid Benhida New Journal of Chemistry, 2017, 41 (22), pp.13760-13772. ⟨10.1039/C7NJ03142D⟩ Article dans une revue hal-02545203v1
	Sweetness prediction of natural compounds Jean-Baptiste Chéron , Iuri Casciuc , Jérôme Golebiowski , Serge Antonczak , Sébastien Fiorucci Food Chemistry, 2017, 221, pp.1421-1425. ⟨10.1016/j.foodchem.2016.10.145⟩ Article dans une revue hal-02545215v1
	Fine-tuning of microsolvation and hydrogen bond interaction regulates substrate channelling in the course of flavonoid biosynthesis Julien Diharce , Jérôme Golebiowski , Sébastien Fiorucci , Serge Antonczak Physical Chemistry Chemical Physics, 2016, 18 (15), pp.10337-10345. ⟨10.1039/C5CP05059F⟩ Article dans une revue hal-02545216v1
	O 2 Migration Rates in [NiFe] Hydrogenases. A Joint Approach Combining Free-Energy Calculations and Kinetic Modeling Jérémie Topin , Julien Diharce , Sébastien Fiorucci , Serge Antonczak , Jérôme Golebiowski Journal of Physical Chemistry B, 2014, 118 (3), pp.676-681. ⟨10.1021/jp4093964⟩ Article dans une revue hal-02545224v1
	Isolation and functional characterization of a τ-cadinol synthase, a new sesquiterpene synthase from Lavandula angustifolia Frédéric Jullien , Sandrine Moja , Aurélie Bony , Sylvain Legrand , Cécile Petit Plant Molecular Biology, 2014, 84 (1-2), pp.227-241. ⟨10.1007/s11103-013-0131-3⟩ Article dans une revue hal-02545231v1
	In vivo characterization of dynein-driven nanovectors using Drosophila oocytes. Nadège Parassol , Céline Bienvenu , Cécile Boglio , Sébastien Fiorucci , Delphine Cerezo PLoS ONE, 2013, 8 (12), pp.e82908. ⟨10.1371/journal.pone.0082908⟩ Article dans une revue hal-00968702v1
	In vivo characterization of dynein-driven nanovectors using Drosophila oocytes. Nadège Parassol , Céline Bienvenu , Cécile Boglio , Sébastien Fiorucci , Delphine Cerezo PLoS ONE, 2013, 8 (12), pp.e82908. ⟨10.1371/journal.pone.0082908⟩ Article dans une revue hal-02545531v1
	Molecular Features Underlying the Perception of Astringency as Probed by Molecular Modeling Jérôme Golebiowski , Sébastien Fiorucci , Martine Adrian-Scotto , Juan Fernandez-Carmona , Serge Antonczak Molecular Informatics, 2011, 30 (5), pp.410-414. ⟨10.1002/minf.201000165⟩ Article dans une revue hal-02545547v1
	Exploiting Antigenic Diversity for Vaccine Design Marco Soriani , Pierre Petit , Renata Grifantini , Roberto Petracca , Giovanni Gancitano Journal of Biological Chemistry, 2010, 285 (39), pp.30126-30138. ⟨10.1074/jbc.M110.118513⟩ Article dans une revue hal-02545563v1
	Binding site prediction and improved scoring during flexible protein-protein docking with ATTRACT Sébastien Fiorucci , Martin Zacharias Proteins - Structure, Function and Bioinformatics, 2010, 78 (15), pp.3131-3139. ⟨10.1002/prot.22808⟩ Article dans une revue hal-02545568v1
	Prediction of Protein-Protein Interaction Sites Using Electrostatic Desolvation Profiles Sébastien Fiorucci , Martin Zacharias Biophysical Journal, 2010, 98 (9), pp.1921-1930. ⟨10.1016/j.bpj.2009.12.4332⟩ Article dans une revue hal-02545575v1
	Theoretical investigations of the role played by quercetinase enzymes upon the flavonoids oxygenolysis mechanism Serge Antonczak , Sébastien Fiorucci , Jérôme Golebiowski , Daniel Cabrol-Bass Physical Chemistry Chemical Physics, 2009, 11 (10), pp.1491. ⟨10.1039/B814588A⟩ Article dans une revue hal-02545593v1
	PTools: an opensource molecular docking library. Adrien Saladin , Sébastien Fiorucci , Pierre Poulain , Chantal Prévost , Martin Zacharias BMC Structural Biology, 2009, 9, pp.27. ⟨10.1186/1472-6807-9-27⟩ Article dans une revue inserm-00474185v1
	Molecular simulations enlighten the binding mode of quercetin to lipoxygenase-3 Sébastien Fiorucci , Jérôme Golebiowski , Daniel Cabrol-Bass , Serge Antonczak Proteins - Structure, Function and Bioinformatics, 2008, 73 (2), pp.290-298. ⟨10.1002/prot.22179⟩ Article dans une revue hal-02545599v1
	Binding free energy prediction in strongly hydrophobic biomolecular systems Landry Charlier , Claude Nespoulous , Sébastien Fiorucci , Serge Antonczak , Jérôme Golebiowski Physical Chemistry Chemical Physics, 2007, 9 (43), pp.5761. ⟨10.1039/B710186D⟩ Article dans une revue hal-02545606v1
	Molecular simulations bring new insights into flavonoid/quercetinase interaction modes Sébastien Fiorucci , Jérôme Golebiowski , Daniel Cabrol-Bass , Serge Antonczak Proteins - Structure, Function and Bioinformatics, 2007, 67 (4), pp.961-970. ⟨10.1002/prot.21380⟩ Article dans une revue hal-02545635v1
	DFT Study of Quercetin Activated Forms Involved in Antiradical, Antioxidant, and Prooxidant Biological Processes Sébastien Fiorucci , Jérôme Golebiowski , Daniel Cabrol-Bass , Serge Antonczak Journal of Agricultural and Food Chemistry, 2007, 55 (3), pp.903-911. ⟨10.1021/jf061864s⟩ Article dans une revue hal-02545619v1
	Mechanistic events underlying odorant binding protein chemoreception Jérôme Golebiowski , Serge Antonczak , Sébastien Fiorucci , Daniel Cabrol-Bass Proteins - Structure, Function and Bioinformatics, 2007, 67 (2), pp.448-458. ⟨10.1002/prot.21307⟩ Article dans une revue hal-02545611v1
	Molecular simulations reveal a new entry site in quercetin 2,3-dioxygenase. A pathway for dioxygen? Sébastien Fiorucci , Jérôme Golebiowski , Daniel Cabrol-Bass , Serge Antonczak Proteins - Structure, Function and Bioinformatics, 2006, 64 (4), pp.845-850. ⟨10.1002/prot.21042⟩ Article dans une revue hal-02545641v1
	Oxygenolysis of Flavonoid Compounds: DFT Description of the Mechanism for Quercetin Sébastien Fiorucci , Jerôme Golebiowski , Daniel Cabrol-Bass , Serge Antonczak ChemPhysChem, 2004, 5 (11), pp.1726-1733. ⟨10.1002/cphc.200400186⟩ Article dans une revue hal-02544658v1

	Reverse chemical ecology in a moth: identification of new behaviorally active semiochemicals in the cotton leafworm Emmanuelle Jacquin-Joly , Gabriela Caballero Vidal , Jérémy Gévar , Sébastien Fiorucci , Nicolas Montagné XII European Congress of Entomology, Oct 2023, Heraklion, Greece Communication dans un congrès hal-04275137v1
	Une IA peut-elle apprendre à sentir ? Sébastien Fiorucci IADATES - "Intelligence Artificielle, Arômes et Parfum", Feb 2023, Grasse, France Communication dans un congrès hal-04275154v1
	Functional genomics and reverse chemical ecology in a moth: identification of new behaviorally active semiochemicals Emmanuelle Jacquin-Joly , Gabriela Caballero Vidal , Arthur Comte , Yang Liu , Guirong Wang The International Conference on Insect Science (ICIS), Aug 2023, Baoding, China Communication dans un congrès hal-04275150v1
	Odorant binding and receptor activation deciphered at the molecular level Matej Hladiš , Sébastien Fiorucci , Jody Pacalon , Maxence Lalis , Jérémie Topin ECRO 2022, Aug 2022, Berlin, France Communication dans un congrès hal-03908204v1
	Predicting odorant-receptor activation with protein language and graph neural networks Matej Hladiš , Sébastien Fiorucci , Maxence Lalis , Jérémie Topin SophIA summit, Nov 2022, Sophia Antipolis, France Communication dans un congrès hal-03908209v1
	Structure-based virtual screening of bitter taste receptors Maxence Lalis , Christine Belloir , Jérémie Topin , Loïc Briand , Sébastien Fiorucci 6. ERNEST meeting, Mar 2022, Virtual meeting, France Communication dans un congrès hal-03790128v1
	Ligand-based virtual screening of membrane proteins Sébastien Fiorucci Winterschool Biomembranes Pharmacology and Therapeutics, Dec 2022, Nice, France Communication dans un congrès hal-03908114v1
	Olfactory receptor ligand prediction via graph neural networks and representation learning Matej Hladiš , Sébastien Fiorucci , Jérôme Golebiowski , Jérémie Topin SophIA summit 2021, Nov 2021, Sophia Antipolis, France Communication dans un congrès hal-03908198v1
	Numerical models contribute to expand the sweet taste chemical space Cédric Bouysset , Christine Belloir , Serge Antonczak , Loïc Briand , Sébastien Fiorucci 16. Weurman Flavour Research Symposium, Elisabeth Guichard; Jean-Luc Le Quéré, May 2021, Virtual meeting (Live and on-demand), France Communication dans un congrès hal-03908171v1
	Representation learning to overcome scarce data in machine learning. Application to chemosensory receptors Matej Hladiš , Sébastien Fiorucci , Jérôme Golebiowski , Jérémie Topin 23e congrès du GGMM et 10e journées de la SFCi, Nov 2021, Lille, France Communication dans un congrès hal-03908186v1
	From genes to perception: decoding chemical senses by numerical and molecular modeling approaches Sébastien Fiorucci 8e Journée Méditerranéenne des Jeunes Chercheurs (JMJC2020), Nov 2020, Toulon, France Communication dans un congrès hal-03908110v1
	Exploring the odor space of Spodoptera littoralis larvae Gabriela Caballero-Vidal , Cédric Bouysset , Sébastien Fiorucci , Jerôme Golebiowski , Camille Meslin European Symposium on Insect Taste and Olfaction, Sep 2019, Villasimius, Italy Communication dans un congrès hal-02546256v1
	Artificial intelligence models predict chemosensory percepts Sébastien Fiorucci Symposium UCA-Monell, Mar 2019, Philadelphie, United States Communication dans un congrès hal-02545809v1
	Modèle numérique des relations structure-saveur Cédric Bouysset , Serge Antonczak , Sébastien Fiorucci GGMM2019, GGMM, Apr 2019, Nice, France Communication dans un congrès hal-02546266v1
	Décrypter le code des odeurs Sébastien Fiorucci Journée « De la Fleur aux Parfums » : Nouvelles Technologies, Intelligence Artificielle & Big Data, Pôle PASS-Terralia, Nov 2019, Grasse, France Communication dans un congrès hal-02545806v1
	Mechanism of GPCR activation triggered by ligands, mutations and protonation Xiaojing Cong , Jean-Baptiste Chéron , Serge Antonczak , Sébastien Fiorucci , Jerôme Golebiowski GGMM2019, GGMM, Apr 2019, Nice, France Communication dans un congrès hal-02546262v1
	Decoding sweet taste from chemical structures Cédric Bouysset , Christine Belloir , Loïc Briand , Serge Antonczak , Sébastien Fiorucci SFCi2019, SFCI, Nov 2019, Paris, France Communication dans un congrès hal-02546236v1
	Reverse chemical ecology expands the list of ligands for a crop pest insect odorant receptor Gabriela Caballero-Vidal , Cédric Bouysset , Sébastien Fiorucci , Nicolas M Montagné , Jerôme Golebiowski XI EBEQ, Brazilian meeting on chemical ecology, Oct 2019, Maceio, Brazil Communication dans un congrès hal-02546245v1
	Prédictions in silico de ligands actifs sur les récepteurs olfactifs du papillon de nuit Spodoptera littoralis Gabriela Caballero-Vidal , Cédric Bouysset , Sébastien Fiorucci , Nicolas Montagne , Jerôme Golebiowski Club de Biologie de l’Insecte, Jun 2019, Albi, France Communication dans un congrès hal-02545807v1
	Artificial Intelligence & Chemical Senses Sébastien Fiorucci 4e réunion du GDR Odorant-Odeur-Olfaction, GDR O3, Dec 2018, Nice, France Communication dans un congrès hal-02545812v1
	Chimioréception de la saveur sucrée Sébastien Fiorucci journée SweetFlavor, Pôle de compétitivité PASS, Oct 2018, Aix-en-Provence, France Communication dans un congrès hal-02545815v1
	Bases moléculaires de la perception chimiosensorielle Sébastien Fiorucci Colloque ARET, May 2018, Dijon, France Communication dans un congrès hal-02545819v1
	Sweet taste receptor: from sequence to structure Jean-Baptiste Chéron , Jerôme Golebiowski , Serge Antonczak , Sébastien Fiorucci JFIC2016, SFC PACA, Apr 2016, Avignon, France Communication dans un congrès hal-02546269v1
	Description théorique d'un phénomène de "substrate channeling" dans la biosynthèse de flavonoïdes Julien Diharce , Jerôme Golebiowski , Sébastien Fiorucci , Serge Antonczak GGMM & GT Enzyme 2015, May 2015, Sète, France Communication dans un congrès hal-02546278v1
	Etude de relations structure-activité du récepteur au goût sucré Jean-Baptiste Chéron , Jerôme Golebiowski , Serge Antonczak , Sébastien Fiorucci 7e journées de la Société Française de Chémoinformatique, SFCI, Oct 2015, Nice, France Communication dans un congrès hal-02546276v1
	Modelling of a metabolon involved in Flavonoid biosynthesis Julien Diharce , Jerôme Golebiowski , Sébastien Fiorucci , Serge Antonczak 27th International Conference on Polyphenols, Sep 2014, Nagoya, Japan Communication dans un congrès hal-02546295v1
	Modelling of a metabolon involved in flavonoid biosynthesis: theoretical strategies Julien Diharce , Jerôme Golebiowski , Sébastien Fiorucci , Serge Antonczak 7Th JFIC-GCIC, May 2014, Turin, Italy Communication dans un congrès hal-02545821v1
	Biosynthèse des flavonoïdes : une étude QM/MM MD de l'étape impliquant l'enzyme DFR Julien Diharce , Jerôme Golebiowski , Sébastien Fiorucci , Serge Antonczak 14e journée francophones des jeunes physico-chimistes, Oct 2013, Fréjus, France Communication dans un congrès hal-02546298v1
	Mécanismes enzymatiques de la production des anthocyanes: une étude par dynamique moléculaire QM/MM de l'étape impliquant DFR Julien Diharce , Iñaki Tuñón , Sébastien Fiorucci , Serge Antonczak 18e congrès GGMM, May 2013, Saint Pierre d'Oléron, France Communication dans un congrès hal-02546310v1
	Experimental and theoretical charaterization of macromolecular assemblies at low resolution Sébastien Fiorucci CFCAM, IBPC, Apr 2013, Paris, France Communication dans un congrès hal-02546313v1
	Contribution de la modélisation moléculaire à la compréhension de la perception olfactive Sébastien Fiorucci Journée interdisciplinaire Thématique Odorant-Odeurs-Olfaction, Jul 2013, Nice, France Communication dans un congrès hal-02546220v1
	Modelling of a metabolon involved in flavonoid biosynthesis Julien Diharce , Jerôme Golebiowski , Sébastien Fiorucci , Serge Antonczak 7th international Workshop on antocyanins, Sep 2013, Porto, Portugal Communication dans un congrès hal-02546302v1
	Theoretical strategies for the modelling of a metabolon involved in flavonoid biosynthesis Julien Diharce , Sébastien Fiorucci , Serge Antonczak 6th Theoretical Biophysics Symposium (Theobio2013), Jun 2013, Göteborg, Sweden Communication dans un congrès hal-02546304v1
	Multiresolution approaches for modeling biomolecular complexes Sébastien Fiorucci Computational Challenges in Structural Biology, Nov 2012, Strasbourg, France Communication dans un congrès hal-02546226v1
	Modeling ligand-receptor interactions at the molecular level. Molecular dynamics used as a computational microscope to decipher the sense of smell Jerôme Golebiowski , Landry Charlier , Jérémie Topin , Sébastien Fiorucci , Serge Antonczak 1er Congrès International ISI, Jun 2011, Meknès, Morocco Communication dans un congrès hal-02546315v1
	Prediction of protein-protein interface using electrostatic profile Sébastien Fiorucci Flexibility and Biological Recognition: from Biophysics to Data Models, INRIA Sophia Antipolis Méditerranée, Mar 2009, Sophia Antipolis, France Communication dans un congrès hal-02546229v1
	Antigen/Antibody docking improvement including hotspot and solvation energy Sébastien Fiorucci , Martin Zacharias BacAbs meeting, Jan 2008, Barcelone, Spain Communication dans un congrès hal-02546320v1
	Electrostatic profiles of targets NMB0033 and CT043 Sébastien Fiorucci , Martin Zacharias BacAbs meeting, Mar 2008, Milan, Italy Communication dans un congrès hal-02546318v1
	Le mécanisme d’oxygénolyse de flavonoïdes : une synergie entre enzyme et substrat Sébastien Fiorucci , Jerôme Golebiowski , Daniel Cabrol-Bass , Serge Antonczak 10ème Rencontre des Chimistes Théoriciens Francophones (RCTF), Jul 2006, Nancy, France Communication dans un congrès hal-02546326v1
	Un nouveau site d'entrée dans l'enzyme Quercetin 2,3-Dioxygénase révélé par simulations de dynamique moléculaire : un canal pour le dioxygène? Serge Antonczak , Sébastien Fiorucci , Daniel Cabrol-Bass , Jerôme Golebiowski 3ème rencontre du Club Métalloprotéines et Modèles, Oct 2005, Carry-Le-Rouet, France Communication dans un congrès hal-02546329v1
	Oxygenolysis of flavonoid compounds. Theoretical mechanism description for the quercetin case Serge Antonczak , Sébastien Fiorucci , Jerôme Golebiowski , Daniel Cabrol-Bass 5th European Conference on Computational Chemistry (EuCo-CC5), Jun 2004, La Londe les Maures, France Communication dans un congrès hal-02546330v1
	Oxygénolyse de flavonoïdes : Etudes DFT du cas de la quercétine Sébastien Fiorucci , Jerôme Golebiowski , Daniel Cabrol-Bass , Serge Antonczak 7ème journée Francophone des Jeunes Physico-Chimistes, Mar 2004, Monastir, Tunisia Communication dans un congrès hal-02546333v1

	Trace amine associated receptors (TAARs) response to amines are largely affected by sequences variants Jody Pacalon , Christine Belloir , Sébastien Fiorucci , Loïc Briand , Jérémie Topin 45. annual meeting - association for chemoreception sciences (AChemS), Apr 2023, Bonita Springs, Florida, United States. Poster de conférence hal-04095283v1
	Trace amine associated receptors (TAARs) response to amines are largely affected by sequences variants Jody Pacalon , Christine Belloir , Sébastien Fiorucci , Loïc Briand , Jérémie Topin 32. international congress of the european-chemoreception-research-organization (ECRO), Aug 2022, Berlin, Germany Poster de conférence hal-03789579v1

	Enzymatic Mechanisms involving Flavonoïds: a Theoretical Point of View Serge Antonczak , Sébastien Fiorucci , Daniel Cabrol-Bass , Jerôme Golebiowski XXIV International Congress on Polyphenol, Jul 2008, Salamanques, Spain. 2008 Proceedings/Recueil des communications hal-02545732v1

	Molecular insights into the structure-function relationships of bitter taste receptors Cédric Bouysset , Jérémie Topin , Yi Wang , Peihua Jiang , Jerôme Golebiowski Chemical Senses, 45 (2), pp.153, 2020, ⟨10.1093/chemse/bjaa007⟩ N°spécial de revue/special issue hal-02545711v1
	Bitter-Taste Receptors: From Sequence to Structure Cédric Bouysset , Jérémie Topin , Serge Antonczak , Meera Rhyu , Jérôme Golebiowski Chemical Senses, 45 (8), pp.800, 2020, ⟨10.1093/chemse/bjaa061⟩ N°spécial de revue/special issue hal-03599130v1
	The anatomy of mammalian sweet taste receptors Jean-Baptiste Chéron , Jerôme Golebiowski , Serge Antonczak , Sébastien Fiorucci Chemical Senses, 41 (9), pp.E179-E179, 2016 N°spécial de revue/special issue hal-02545720v1
	Structure-function of Odorant and Sweet-taste Recept.ors Based on Molecular Modeling Jerôme Golebiowski , Claire A. de March , Jean-Baptiste Chéron , Sébastien Fiorucci , Serge Antonczak Chemical Senses, 41 (7), pp.E83-E83, 2016 N°spécial de revue/special issue hal-02545724v1
	Deciphering the odorant binding protein-olfactory receptor interactions Marilyne Viano , Kyung Sook Kim , William A. Goddard , Claire A. de March , Jerôme Golebiowski Chemical Senses, 40 (3), pp.E242-E242, 2015 N°spécial de revue/special issue hal-02545729v1

	Natural Sweeteners Jean-Baptiste Chéron , Axel Marchal , Sébastien Fiorucci Encyclopedia of Food Chemistry, Elsevier, pp.189-195, 2019, ⟨10.1016/B978-0-08-100596-5.21620-X⟩ Chapitre d'ouvrage hal-02545197v1
	Computational Antigenic Epitope Prediction by Calculating Electrostatic Desolvation Penalties of Protein Surfaces Sébastien Fiorucci , Martin Zacharias Immunoinformatics, pp.365-374, 2014, ⟨10.1007/978-1-4939-1115-8_20⟩ Chapitre d'ouvrage hal-02545222v1
	Molecular features underlying the chemoreception of odorant binding proteins and olfactory receptors. Insights from molecular modeling and biophysical data Jerôme Golebiowski , Landry Charlier , Jérémie Topin , Sébastien Fiorucci , Serge Antonczak Academic Press. Flavour Science, 1, Elsevier, pp.221-232, 2013 Chapitre d'ouvrage hal-02545701v1
	ATTRACT and PTOOLS: Open Source Programs for Protein–Protein Docking Sebastian Schneider , Adrien Saladin , Sébastien Fiorucci , Chantal Prévost , Martin Zacharias Springer, New York, NY. Computational Drug Discovery and Design, 819, pp.221-232, 2012, Methods in Molecular Biology (Methods and Protocols), ⟨10.1007/978-1-61779-465-0_15⟩ Chapitre d'ouvrage hal-02545543v1
	Prediction and Calculation of Protein–Protein Binding Affinities and Mutation Effects Sébastien Fiorucci , Serge Antonczak , Jérôme Golebiowski Protein-Protein Complexes, IMPERIAL COLLEGE PRESS, pp.295-317, 2010, ⟨10.1142/9781848163409_0011⟩ Chapitre d'ouvrage hal-02545579v1

	Activités biologiques de composés de la famille des flavonoïdes : approches par des méthodes de chimie quantique et de dynamique moléculaire Sébastien Fiorucci Chimie. Université de Nice Sophia-Antipolis (UNS), 2006. Français. ⟨NNT : ⟩ Thèse tel-02545765v1

	Simulations moléculaires des interactions ligand-récepteur : Bases moléculaires de la perception chimio-sensorielle Sébastien Fiorucci Chimie. Université Nice Sophia Antipolis [UNS]; Université Côte D'Azur, 2017 HDR tel-02545797v1

Sébastien FIORUCCI

Publications

M2OR: a database of olfactory receptor–odorant pairs for understanding the molecular mechanisms of olfaction

Exploring Dihydroflavonol‐4‐Reductase Reactivity and Selectivity by QM/MM‐MD Simulations

Reverse chemical ecology in a moth: machine learning on odorant receptors identifies new behaviorally active agonists

ProLIF: a library to encode molecular interactions as fingerprints

Functional molecular switches of mammalian G protein-coupled bitter-taste receptors

Corrigendum to: More than smell. COVID-19 is associated with severe impairment of smell, taste, and chemesthesis

Machine learning decodes chemical features to identify novel agonists of a moth odorant receptor

Novel scaffold of natural compound eliciting sweet taste revealed by machine learning

More than smell. COVID-19 is associated with severe impairment of smell, taste, and chemesthesis

Metal Ions Activate the Human Taste Receptor TAS2R7

Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts

Conserved Residues Control the T1R3-Specific Allosteric Signaling Pathway of the Mammalian Sweet-Taste Receptor

Allosteric Modulation Mechanism of the mGluR 5 Transmembrane Domain

Agonists of G-Protein-Coupled Odorant Receptors Are Predicted from Chemical Features

Activation Dynamics of the Neurotensin G Protein-Coupled Receptor 1

The anatomy of mammalian sweet taste receptors

Ces molécules qui éveillent nos papilles

Update of the ATTRACT force field for the prediction of protein-protein binding affinity

Bornyl-diphosphate synthase from Lavandula angustifolia: A major monoterpene synthase involved in essential oil quality

Design, synthesis and photophysical studies of styryl-based push–pull fluorophores with remarkable solvatofluorochromism

Sweetness prediction of natural compounds

Fine-tuning of microsolvation and hydrogen bond interaction regulates substrate channelling in the course of flavonoid biosynthesis

O 2 Migration Rates in [NiFe] Hydrogenases. A Joint Approach Combining Free-Energy Calculations and Kinetic Modeling

Isolation and functional characterization of a τ-cadinol synthase, a new sesquiterpene synthase from Lavandula angustifolia

In vivo characterization of dynein-driven nanovectors using Drosophila oocytes.

In vivo characterization of dynein-driven nanovectors using Drosophila oocytes.

Molecular Features Underlying the Perception of Astringency as Probed by Molecular Modeling

Exploiting Antigenic Diversity for Vaccine Design

Binding site prediction and improved scoring during flexible protein-protein docking with ATTRACT

Prediction of Protein-Protein Interaction Sites Using Electrostatic Desolvation Profiles

Theoretical investigations of the role played by quercetinase enzymes upon the flavonoids oxygenolysis mechanism

PTools: an opensource molecular docking library.

Molecular simulations enlighten the binding mode of quercetin to lipoxygenase-3

Binding free energy prediction in strongly hydrophobic biomolecular systems

Molecular simulations bring new insights into flavonoid/quercetinase interaction modes

DFT Study of Quercetin Activated Forms Involved in Antiradical, Antioxidant, and Prooxidant Biological Processes

Mechanistic events underlying odorant binding protein chemoreception

Molecular simulations reveal a new entry site in quercetin 2,3-dioxygenase. A pathway for dioxygen?

Oxygenolysis of Flavonoid Compounds: DFT Description of the Mechanism for Quercetin

Reverse chemical ecology in a moth: identification of new behaviorally active semiochemicals in the cotton leafworm

Une IA peut-elle apprendre à sentir ?

Functional genomics and reverse chemical ecology in a moth: identification of new behaviorally active semiochemicals

Odorant binding and receptor activation deciphered at the molecular level

Predicting odorant-receptor activation with protein language and graph neural networks

Structure-based virtual screening of bitter taste receptors

Ligand-based virtual screening of membrane proteins

Olfactory receptor ligand prediction via graph neural networks and representation learning

Numerical models contribute to expand the sweet taste chemical space

Representation learning to overcome scarce data in machine learning. Application to chemosensory receptors

From genes to perception: decoding chemical senses by numerical and molecular modeling approaches

Exploring the odor space of Spodoptera littoralis larvae

Artificial intelligence models predict chemosensory percepts

Modèle numérique des relations structure-saveur

Décrypter le code des odeurs

Mechanism of GPCR activation triggered by ligands, mutations and protonation

Decoding sweet taste from chemical structures

Reverse chemical ecology expands the list of ligands for a crop pest insect odorant receptor

Prédictions in silico de ligands actifs sur les récepteurs olfactifs du papillon de nuit Spodoptera littoralis

Artificial Intelligence & Chemical Senses

Chimioréception de la saveur sucrée

Bases moléculaires de la perception chimiosensorielle

Sweet taste receptor: from sequence to structure

Description théorique d'un phénomène de "substrate channeling" dans la biosynthèse de flavonoïdes

Etude de relations structure-activité du récepteur au goût sucré

Modelling of a metabolon involved in Flavonoid biosynthesis

Modelling of a metabolon involved in flavonoid biosynthesis: theoretical strategies

Biosynthèse des flavonoïdes : une étude QM/MM MD de l'étape impliquant l'enzyme DFR

Mécanismes enzymatiques de la production des anthocyanes: une étude par dynamique moléculaire QM/MM de l'étape impliquant DFR

Experimental and theoretical charaterization of macromolecular assemblies at low resolution

Contribution de la modélisation moléculaire à la compréhension de la perception olfactive

Modelling of a metabolon involved in flavonoid biosynthesis

Theoretical strategies for the modelling of a metabolon involved in flavonoid biosynthesis

Multiresolution approaches for modeling biomolecular complexes

Modeling ligand-receptor interactions at the molecular level. Molecular dynamics used as a computational microscope to decipher the sense of smell

Prediction of protein-protein interface using electrostatic profile

Antigen/Antibody docking improvement including hotspot and solvation energy

Electrostatic profiles of targets NMB0033 and CT043

Le mécanisme d’oxygénolyse de flavonoïdes : une synergie entre enzyme et substrat