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Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future
Alain Beck
,
Valentina D’atri
,
Anthony Ehkirch
,
Szabolcs Fekete
,
Oscar Hernandez-Alba
,
et al.
Article dans une revue
hal-02272143v1
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Cysteine‐Cysteine Cross‐Conjugation of both Peptides and Proteins with a Bifunctional Hypervalent Iodine‐Electrophilic Reagent
Ilias Koutsopetras
,
Abhaya Kumar Mishra
,
Rania Benazza
,
Oscar Hernandez-Alba
,
Sarah Cianférani
,
et al.
Article dans une revue
hal-04234983v1
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A Case Study to Identify the Drug Conjugation Site of a Site-Specific Antibody-Drug-Conjugate Using Middle-Down Mass Spectrometry
Oscar Hernandez-Alba
,
Stéphane Houel
,
Steve Hessmann
,
Stéphane Erb
,
David Rabuka
,
et al.
Article dans une revue
hal-02341587v1
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Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates
Alain Beck
,
Guillaume Terral
,
François Debaene
,
Elsa Wagner-Rousset
,
Julien Marcoux
,
et al.
Article dans une revue
hal-02335539v1
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Insights from native mass spectrometry approaches for top-and middle-level characterization of site-specific antibody-drug conjugates
T. Botzanowski
,
S. Erb
,
O. Hernandez-Alba
,
A. Ehkirch
,
O. Colas
,
et al.
Article dans une revue
hal-02960850v1
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Molecular determinants of MED1 interaction with the DNA bound VDR–RXR heterodimer
Y Belorusova Anna
,
Maxime Bourguet
,
Steve Hessmann
,
Sandra Chalhoub
,
Bruno Kieffer
,
et al.
Article dans une revue
hal-02962412v1
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The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles
Michael Coulter
,
Cristina Dorobantu
,
Gerrald Lodewijk
,
Francois Delalande
,
Sarah Cianférani
,
et al.
Article dans une revue
hal-02338285v1
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Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains
Mattia Mori
,
Lesia Kovalenko
,
Savina Malancona
,
Francesco Saladini
,
Davide de Forni
,
et al.
Article dans une revue
hal-02326492v1
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Evidence for the Formation of a Covalent Thiosulfinate Intermediate with Peroxiredoxin in the Catalytic Mechanism of Sulfiredoxin
Xavier Roussel
,
Guillaume Béchade
,
Alexandre Kriznik
,
Alain van Dorsselaer
,
Sarah Sanglier-Cianferani
,
et al.
Article dans une revue
hal-01652689v1
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Computational strategies and challenges for using native ion mobility mass spectrometry in biophysics and structural biology
Timothy M. Allison
,
Perdita Barran
,
Sarah Cianférani
,
Matteo T. Degiacomi
,
Valérie Gabelica
,
et al.
Article dans une revue
hal-02960838v1
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A structural signature motif enlightens the origin and diversification of nuclear receptors
Brice Beinsteiner
,
Gabriel V Markov
,
Stéphane Erb
,
Yassmine Chebaro
,
Alastair G Mcewen
,
et al.
Article dans une revue
hal-03222330v1
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Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction
Benjamin Rothé
,
Jean-Michel Saliou
,
Marc Quinternet
,
Régis Back
,
Decebal Tiotiu
,
et al.
Article dans une revue
hal-02279890v1
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Denaturing mass photometry for straightforward optimization of protein-protein cross-linking reactions at single-molecule level
Hugo Gizardin-Fredon
,
Paulo E Santo
,
Marie-Eve Chagot
,
Bruno Charpentier
,
Tiago M Bandeiras
,
et al.
2024
Pré-publication, Document de travail
hal-04535064v1
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Combining native MS approaches to decipher archaeal box H/ACA ribonucleoprotein particle structure and activity
Jean-Michel Saliou
,
Xavier Manival
,
Anne-Sophie Tillault
,
Cédric Atmanene
,
Claude Bobo
,
et al.
Article dans une revue
istex
hal-01451673v1
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Computational and Mass-Spectrometry-Based Workflow for the Discovery and Validation of Missing Human Proteins: Application to Chromosomes 2 and 14
Christine Carapito
,
Lydie Lane
,
Mohamed Benama
,
Alisson Opsomer
,
Emmanuelle Mouton-Barbosa
,
et al.
Article dans une revue
hal-02191518v1
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Online Collision-Induced Unfolding of Therapeutic Monoclonal Antibody Glyco-Variants through Direct Hyphenation of Cation Exchange Chromatography with Native Ion Mobility–Mass Spectrometry
Guusje van Schaick
,
Elena Domínguez-Vega
,
Jérôme Castel
,
Manfred Wuhrer
,
Oscar Hernandez-Alba
,
et al.
Article dans une revue
hal-04234934v1
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In situ targeted activation of an anticancer agent using ultrasound-triggered release of composite droplets
Sergii Kolodych
,
Chloé Michel
,
Sébastien Delacroix
,
Oleksandr Koniev
,
Anthony Ehkirch
,
et al.
Article dans une revue
hal-02174984v1
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Characterization of the Methionine Sulfoxide Reductase Activities of PILB, a Probable Virulence Factor from Neisseria meningitidis
Alexandre Olry
,
Sandrine Boschi-Muller
,
Michel Marraud
,
Sarah Sanglier-Cianferani
,
Alain van Dorsselear
,
et al.
Article dans une revue
hal-01690847v1
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A Class of Valuable (Pro-)Activity-Based Protein Profiling Probes: Application to the Redox-Active Antiplasmodial Agent, Plasmodione
Bogdan Cichocki
,
Vrushali Khobragade
,
Maxime Donzel
,
Leandro Cotos Munoz
,
Stephanie Blandin
,
et al.
Article dans une revue
hal-03243960v1
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2-D Structure of the A Region of Xist RNA and Its Implication for PRC2 Association
Sylvain Maenner
,
Magali Blaud
,
Laetitia Fouillen
,
Anne Savoye
,
Virginie Marchand
,
et al.
Article dans une revue
hal-01715217v1
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Recent advances in structural mass spectrometry methods in the context of biosimilarity assessment: from sequence heterogeneities to higher order structures
Jérôme Castel
,
Sarah Delaux
,
Oscar Hernandez-Alba
,
Sarah Cianférani
Article dans une revue
hal-04234974v1
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Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor
Kareem Mohideen-Abdul
,
Karima Tazibt
,
Maxime Bourguet
,
Isabelle Hazemann
,
Isabelle Lebars
,
et al.
Article dans une revue
inserm-02409726v1
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A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis
Julien Marcoux
,
P Patrizia Mangione
,
Riccardo Porcari
,
Matteo Degiacomi
,
Guglielmo Verona
,
et al.
Article dans une revue
hal-02335545v1
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Towards automation of Collision Induced Unfolding experiments through online Size Exclusion Chromatography coupled to native Mass Spectrometry
Evolène Deslignière
,
Anthony Ehkirch
,
Thomas Botzanowski
,
Alain Beck
,
Oscar Hernandez-Alba
,
et al.
Article dans une revue
hal-02960860v1
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Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
Christian Boehler
,
Laurent R Gauthier
,
Oliver Mortusewicz
,
Denis S Biard
,
Jean-Michel Saliou
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (7), pp.2783-8. ⟨10.1073/pnas.1016574108⟩
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hal-02369944v1
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A Direct One-Pot Synthesis of Asymmetric Dehydrobenzopyrido[12]annulenes and Their Physicochemical Properties
Paul Baxter
,
Lydia Karmazin
,
André Decian
,
Alexandre Varnek
,
Jean Paul Gisselbrecht
,
et al.
Article dans une revue
hal-03151673v1
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An Investigation into the Stephens-Castro Synthesis of Dehydrotriaryl[12]annulenes: Factors Influencing the Cyclotrimerization
Paul Baxter
,
Abdelaziz Al Ouahabi
,
Lydia Karmazin
,
Alexandre Varnek
,
Jean-Marc Strub
,
et al.
Article dans une revue
hal-02345053v1
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Probing the mechanism of the peroxiredoxin decamer interaction with its reductase sulfiredoxin from the single molecule to the solution scale
Audrey Beaussart
,
Florent Canonico
,
Hortense Mazon
,
Jorge Hidalgo
,
Sarah Cianférani
,
et al.
Article dans une revue
hal-03595966v1
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Measuring the NQO2: Melatonin Complex by Native Nano-Electrospray Ionization Mass Spectrometry
Jean Boutin
,
Johann Stojko
,
Gilles Ferry
,
Sarah Cianférani
Chapitre d'ouvrage
hal-03843794v1
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Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex
Alexandre Berthier
,
Manjula Vinod
,
Geoffrey Porez
,
Agata Steenackers
,
Jérémy Alexandre
,
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (47), pp.11033-11042. ⟨10.1073/pnas.1805397115⟩
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inserm-01924835v1
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