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Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future

Alain Beck , Valentina D’atri , Anthony Ehkirch , Szabolcs Fekete , Oscar Hernandez-Alba , et al.
Expert Review of Proteomics, 2019, 16 (4), pp.337-362. ⟨10.1080/14789450.2019.1578215⟩
Article dans une revue hal-02272143v1
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Cysteine‐Cysteine Cross‐Conjugation of both Peptides and Proteins with a Bifunctional Hypervalent Iodine‐Electrophilic Reagent

Ilias Koutsopetras , Abhaya Kumar Mishra , Rania Benazza , Oscar Hernandez-Alba , Sarah Cianférani , et al.
Chemistry - A European Journal, In press, ⟨10.1002/chem.202302689⟩
Article dans une revue hal-04234983v1
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A Case Study to Identify the Drug Conjugation Site of a Site-Specific Antibody-Drug-Conjugate Using Middle-Down Mass Spectrometry

Oscar Hernandez-Alba , Stéphane Houel , Steve Hessmann , Stéphane Erb , David Rabuka , et al.
Journal of The American Society for Mass Spectrometry, 2019, 30 (11), ⟨10.1007/s13361-019-02296-2⟩
Article dans une revue hal-02341587v1
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Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates

Alain Beck , Guillaume Terral , François Debaene , Elsa Wagner-Rousset , Julien Marcoux , et al.
Expert Review of Proteomics, 2016, 13 (2), pp.157-183. ⟨10.1586/14789450.2016.1132167⟩
Article dans une revue hal-02335539v1
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Insights from native mass spectrometry approaches for top-and middle-level characterization of site-specific antibody-drug conjugates

T. Botzanowski , S. Erb , O. Hernandez-Alba , A. Ehkirch , O. Colas , et al.
mAbs, 2017, 9 (5), pp.801-811. ⟨10.1080/19420862.2017.1316914⟩
Article dans une revue hal-02960850v1
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Molecular determinants of MED1 interaction with the DNA bound VDR–RXR heterodimer

Y Belorusova Anna , Maxime Bourguet , Steve Hessmann , Sandra Chalhoub , Bruno Kieffer , et al.
Nucleic Acids Research, 2020, ⟨10.1093/nar/gkaa775⟩
Article dans une revue hal-02962412v1
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The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles

Michael Coulter , Cristina Dorobantu , Gerrald Lodewijk , Francois Delalande , Sarah Cianférani , et al.
Cell Reports, 2018, 24 (4), pp.973-986.e8. ⟨10.1016/j.celrep.2018.06.100⟩
Article dans une revue hal-02338285v1

Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains

Mattia Mori , Lesia Kovalenko , Savina Malancona , Francesco Saladini , Davide de Forni , et al.
ACS Chemical Biology, 2018, 13 (1), pp.253-266. ⟨10.1021/acschembio.7b00907⟩
Article dans une revue hal-02326492v1
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Evidence for the Formation of a Covalent Thiosulfinate Intermediate with Peroxiredoxin in the Catalytic Mechanism of Sulfiredoxin

Xavier Roussel , Guillaume Béchade , Alexandre Kriznik , Alain van Dorsselaer , Sarah Sanglier-Cianferani , et al.
Journal of Biological Chemistry, 2008, 283 (33), pp.22371-22382. ⟨10.1074/jbc.M800493200⟩
Article dans une revue hal-01652689v1
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Computational strategies and challenges for using native ion mobility mass spectrometry in biophysics and structural biology

Timothy M. Allison , Perdita Barran , Sarah Cianférani , Matteo T. Degiacomi , Valérie Gabelica , et al.
Analytical Chemistry, 2020, 92 (16), pp.10872-10880. ⟨10.1021/acs.analchem.9b05791⟩
Article dans une revue hal-02960838v1
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A structural signature motif enlightens the origin and diversification of nuclear receptors

Brice Beinsteiner , Gabriel V Markov , Stéphane Erb , Yassmine Chebaro , Alastair G Mcewen , et al.
PLoS Genetics, 2021, 17 (4), pp.e1009492. ⟨10.1371/journal.pgen.1009492⟩
Article dans une revue hal-03222330v1

Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction

Benjamin Rothé , Jean-Michel Saliou , Marc Quinternet , Régis Back , Decebal Tiotiu , et al.
Nucleic Acids Research, 2014, 42 (16), pp.10731-10747. ⟨10.1093/nar/gku612⟩
Article dans une revue hal-02279890v1
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Denaturing mass photometry for straightforward optimization of protein-protein cross-linking reactions at single-molecule level

Hugo Gizardin-Fredon , Paulo E Santo , Marie-Eve Chagot , Bruno Charpentier , Tiago M Bandeiras , et al.
2024
Pré-publication, Document de travail hal-04535064v1

Combining native MS approaches to decipher archaeal box H/ACA ribonucleoprotein particle structure and activity

Jean-Michel Saliou , Xavier Manival , Anne-Sophie Tillault , Cédric Atmanene , Claude Bobo , et al.
Proteomics, 2015, 15 (16), pp.2851--2861. ⟨10.1002/pmic.201400529⟩
Article dans une revue istex hal-01451673v1

Computational and Mass-Spectrometry-Based Workflow for the Discovery and Validation of Missing Human Proteins: Application to Chromosomes 2 and 14

Christine Carapito , Lydie Lane , Mohamed Benama , Alisson Opsomer , Emmanuelle Mouton-Barbosa , et al.
Journal of Proteome Research, 2015, 14 (9), pp.3621-3634. ⟨10.1021/pr5010345⟩
Article dans une revue hal-02191518v1
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Online Collision-Induced Unfolding of Therapeutic Monoclonal Antibody Glyco-Variants through Direct Hyphenation of Cation Exchange Chromatography with Native Ion Mobility–Mass Spectrometry

Guusje van Schaick , Elena Domínguez-Vega , Jérôme Castel , Manfred Wuhrer , Oscar Hernandez-Alba , et al.
Analytical Chemistry, 2023, 95 (8), pp.3932-3939. ⟨10.1021/acs.analchem.2c03163⟩
Article dans une revue hal-04234934v1

In situ targeted activation of an anticancer agent using ultrasound-triggered release of composite droplets

Sergii Kolodych , Chloé Michel , Sébastien Delacroix , Oleksandr Koniev , Anthony Ehkirch , et al.
European Journal of Medicinal Chemistry, 2017, 142, pp.2-7. ⟨10.1016/j.ejmech.2017.03.057⟩
Article dans une revue hal-02174984v1
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Characterization of the Methionine Sulfoxide Reductase Activities of PILB, a Probable Virulence Factor from Neisseria meningitidis

Alexandre Olry , Sandrine Boschi-Muller , Michel Marraud , Sarah Sanglier-Cianferani , Alain van Dorsselear , et al.
Journal of Biological Chemistry, 2002, 277 (14), pp.12016-12022. ⟨10.1074/jbc.M112350200⟩
Article dans une revue hal-01690847v1
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A Class of Valuable (Pro-)Activity-Based Protein Profiling Probes: Application to the Redox-Active Antiplasmodial Agent, Plasmodione

Bogdan Cichocki , Vrushali Khobragade , Maxime Donzel , Leandro Cotos Munoz , Stephanie Blandin , et al.
JACS Au, 2021, 1 (5), pp.669-689. ⟨10.1021/jacsau.1c00025⟩
Article dans une revue hal-03243960v1
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2-D Structure of the A Region of Xist RNA and Its Implication for PRC2 Association

Sylvain Maenner , Magali Blaud , Laetitia Fouillen , Anne Savoye , Virginie Marchand , et al.
PLoS Biology, 2010, 8 (1), pp.e1000276. ⟨10.1371/journal.pbio.1000276⟩
Article dans une revue hal-01715217v1
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Recent advances in structural mass spectrometry methods in the context of biosimilarity assessment: from sequence heterogeneities to higher order structures

Jérôme Castel , Sarah Delaux , Oscar Hernandez-Alba , Sarah Cianférani
Journal of Pharmaceutical and Biomedical Analysis, 2023, 236, pp.115696. ⟨10.1016/j.jpba.2023.115696⟩
Article dans une revue hal-04234974v1
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Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor

Kareem Mohideen-Abdul , Karima Tazibt , Maxime Bourguet , Isabelle Hazemann , Isabelle Lebars , et al.
Frontiers in Endocrinology, 2017, 8, pp.140. ⟨10.3389/fendo.2017.00140⟩
Article dans une revue inserm-02409726v1
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A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis

Julien Marcoux , P Patrizia Mangione , Riccardo Porcari , Matteo Degiacomi , Guglielmo Verona , et al.
EMBO Molecular Medicine, 2015, 7 (10), pp.1337-1349. ⟨10.15252/emmm.201505357⟩
Article dans une revue hal-02335545v1
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Towards automation of Collision Induced Unfolding experiments through online Size Exclusion Chromatography coupled to native Mass Spectrometry

Evolène Deslignière , Anthony Ehkirch , Thomas Botzanowski , Alain Beck , Oscar Hernandez-Alba , et al.
Analytical Chemistry, 2020, 92 (19), pp.12900-12908. ⟨10.1021/acs.analchem.0c01426⟩
Article dans une revue hal-02960860v1

Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression

Christian Boehler , Laurent R Gauthier , Oliver Mortusewicz , Denis S Biard , Jean-Michel Saliou , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (7), pp.2783-8. ⟨10.1073/pnas.1016574108⟩
Article dans une revue hal-02369944v1

A Direct One-Pot Synthesis of Asymmetric Dehydrobenzopyrido[12]annulenes and Their Physicochemical Properties

Paul Baxter , Lydia Karmazin , André Decian , Alexandre Varnek , Jean Paul Gisselbrecht , et al.
European Journal of Organic Chemistry, 2017, 2017 (31), pp.4625-4632. ⟨10.1002/ejoc.201700700⟩
Article dans une revue hal-03151673v1

An Investigation into the Stephens-Castro Synthesis of Dehydrotriaryl[12]annulenes: Factors Influencing the Cyclotrimerization

Paul Baxter , Abdelaziz Al Ouahabi , Lydia Karmazin , Alexandre Varnek , Jean-Marc Strub , et al.
European Journal of Organic Chemistry, 2019, 2019 (40), pp.6783-6795. ⟨10.1002/ejoc.201901053⟩
Article dans une revue hal-02345053v1
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Probing the mechanism of the peroxiredoxin decamer interaction with its reductase sulfiredoxin from the single molecule to the solution scale

Audrey Beaussart , Florent Canonico , Hortense Mazon , Jorge Hidalgo , Sarah Cianférani , et al.
Nanoscale Horizons, 2022, 7 (5), pp.515-525. ⟨10.1039/d2nh00037g⟩
Article dans une revue hal-03595966v1
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Measuring the NQO2: Melatonin Complex by Native Nano-Electrospray Ionization Mass Spectrometry

Jean Boutin , Johann Stojko , Gilles Ferry , Sarah Cianférani
Melatonin, 2550, Springer US, pp.323-328, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2593-4_34⟩
Chapitre d'ouvrage hal-03843794v1
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Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex

Alexandre Berthier , Manjula Vinod , Geoffrey Porez , Agata Steenackers , Jérémy Alexandre , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (47), pp.11033-11042. ⟨10.1073/pnas.1805397115⟩
Article dans une revue inserm-01924835v1