Sandrine Vadon - Le Goff

Documents

Publications

	Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases Sandrine Vadon-Le Goff , Agnès Tessier , Manon Napoli , Cindy Dieryckx , Julien Bauer Nature Communications, 2023, 14 (1), ⟨10.1038/s41467-023-43401-0⟩ Article dans une revue hal-04350568v1
	Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system Marine Blanc , Clara Lettl , Jérémy Guérin , Anaïs Vieille , Sven Furler PLoS Pathogens, 2023, 19 (5), pp.e1011368. ⟨10.1371/journal.ppat.1011368⟩ Article dans une revue hal-04246055v1
	Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1) Urvashi Sharma , Sandrine Vadon-Le Goff , Karl Harlos , Yuguang Zhao , Natacha Mariano Scientific Reports, 2022, 12, pp.14850. ⟨10.1038/s41598-022-18795-4⟩ Article dans une revue hal-03838405v1
	Procollagen C-proteinase enhancer-1 (PCPE-1), a potential biomarker and therapeutic target for fibrosis Priscillia Lagoutte , Emmanuel Bettler , Sandrine Vadon-Le Goff , Catherine Moali Matrix Biology Plus, 2021, 11, pp.100062. ⟨10.1016/j.mbplus.2021.100062⟩ Article dans une revue hal-03368863v1
	BMP-1 disrupts cell adhesion and enhances TGF-β activation through cleavage of the matricellular protein thrombospondin-1 Cyril Anastasi , Patricia Rousselle , Maya Talantikite , Agnès Tessier , Caroline Cluzel Science Signaling, 2020, 13 (639), pp.eaba3880. ⟨10.1126/scisignal.aba3880⟩ Article dans une revue hal-02991455v1
	Inhibitors of BMP-1/tolloid-like proteinases: efficacy, selectivity and cellular toxicity Maya Talantikite , Pascaline Lecorché , Fabrice Beau , Odile Damour , Christoph Becker-Pauly FEBS Open Bio, 2018, 8 (12), pp.2011-2021. ⟨10.1002/2211-5463.12540⟩ Article dans une revue hal-02342437v1
	Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1 David Pulido , Urvashi Sharma , Sandrine Vadon-Le Goff , Sadaf-Ahmahni Hussain , Sarah Cordes Structure, 2018, 26 (10), pp.1384-1392.e3. ⟨10.1016/j.str.2018.06.011⟩ Article dans une revue hal-03094449v1
	Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1 David Pulido , Urvashi Sharma , Sandrine Vadon-Le Goff , Sadaf-Ahmahni Hussain , Sarah Cordes Structure, 2018, 26 (10), pp.1384-1392.e3. ⟨10.1016/j.str.2018.06.011⟩ Article dans une revue hal-02342439v1
	Interaction of Complement Defence Collagens C1q and Mannose-Binding Lectin with BMP-1/Tolloid-like Proteinases Monique Lacroix , Agnès Tessier , Chantal Dumestre-Pérard , Sandrine Vadon-Le Goff , Evelyne Gout Scientific Reports, 2017, 7, pp.16958. ⟨10.1038/s41598-017-17318-w⟩ Article dans une revue hal-01657764v1
	Deficiency of the DSPP-cleaving enzymes meprin α and meprin β does not result in dentin malformation in mice Philipp Arnold , Lara Koopmann , Florian Peters , Falk Birkenfeld , Sandrine Vadon-Le Goff Cell and Tissue Research, 2017, 367 (2), pp.351-358. ⟨10.1007/s00441-016-2498-3⟩ Article dans une revue hal-02342448v1
	Structural basis of homo- and heterotrimerization of collagen I Urvashi Sharma , Loïc Carrique , Sandrine Vadon-Le Goff , Natacha Mariano , Rainier-Numa Georges Nature Communications, 2017, 8 (1), ⟨10.1038/ncomms14671⟩ Article dans une revue hal-02342446v1
	Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-β signaling as primary targets Mourad Bekhouche , Cedric Leduc , Laura Dupont , Lauriane Janssen , Frédéric Delolme FASEB Journal, 2016, 30 (5), pp.1741-1756. ⟨10.1096/fj.15-279869⟩ Article dans une revue hal-02342452v1
	BMP-1/tolloid-like proteinases synchronize matrix assembly with growth factor activation to promote morphogenesis and tissue remodeling Sandrine Vadon-Le Goff , David J.S. Hulmes , Catherine Moali Matrix Biology, 2015, 44-46, pp.14-23. ⟨10.1016/j.matbio.2015.02.006⟩ Article dans une revue hal-02342455v1
	Proteolytic control of TGF-β co-receptor activity by BMP-1/tolloid-like proteases revealed by quantitative iTRAQ proteomics Frédéric Delolme , Cyril Anastasi , Lindsay B Alcaraz , Valentin Mendoza , Sandrine Vadon-Le Goff Cellular and Molecular Life Sciences, 2015, 72 (5), pp.1009-1027. ⟨10.1007/s00018-014-1733-x⟩ Article dans une revue hal-02283031v1
	Procollagen C-proteinase enhancer grasps the stalk of the C-propeptide trimer to boost collagen precursor maturation. Jean-Marie Bourhis , Sandrine Vadon-Le Goff , Hassnae Afrache , Natacha Mariano , Daniel Kronenberg Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (16), pp.6394-9 Article dans une revue hal-01322415v1
	IMPROVED AND HIGH YIELD SYNTHESIS OF THE POTENT ARGINASE INHIBITOR : 2(S)-AMINO-6-BORONOHEXANOIC ACID Sandrine Vadon-Le Goff , Sylvie Dijols , Daniel Mansuy , Jean-Luc Boucher Organic Process Research and Development, 2005, 9, pp.677-679 Article dans une revue hal-00097853v1
	SYNTHESIS AND EVALUATION OF NEW OMEGA-BORONO-ALPHA-AMINOACIDS AS RAT LIVER ARGINASE INHIBITORS Olivier Busnel , François Carreaux , Bertrand Carboni , Stéphanie Pethe , Sandrine Vadon-Le Goff Bioorganic and Medicinal Chemistry, 2005, 13, pp.2373-2379 Article dans une revue hal-00097475v1
	Coordination chemistry of the heme in cystathionine beta-synthase: formation of iron(II)-isonitrile complexes. S. Vadon-Legoff , M. Delaforge , Jl Boucher , M. Janosik , Jp Kraus Biochemical and Biophysical Research Communications, 2001, 283, pp.487-492 Article dans une revue hal-00315217v1
	Modulation of cholinergic airway reactivity and nitric oxide production by endogenous arginase activity. H. Meurs , Ma Hamer , S. Pethe , S. Vadon-Legoff , Jl Boucher British Journal of Pharmacology, 2000, 130, pp.1793-1798 Article dans une revue hal-00315218v1
	Biosynthèse du monoxyde d'azote (NO) : mécanisme, régulation et contrôle Nicolas Sennequier , Sandrine Vadon-Le Goff Médecine/Sciences, 1998, 14 (11), pp.1185-1195 Article dans une revue hal-00127937v1
	N-omega-OH-D,L-indospicine, a potent and selective: Inhibitor of arginase in rat and rabbit alveolar macrophages (AM phi) can promote utilization of L-arginine by nitric oxide synthase (NOS) C. Hey , Jl Boucher , S. Vadon , G. Ketterer , C. Stichnote British Journal of Pharmacology, 1997, 120, pp.P48-P48 Article dans une revue hal-00315247v1
	Inhibition of arginase in rat and rabbit alveolar macrophages by N omega-hydroxy-D,L-indospicine, effects on L-arginine utilization by nitric oxide synthase. C. Hey , Jl Boucher , S. Vadon-Legoff , G. Ketterer , I. Wessler British Journal of Pharmacology, 1997, 121, pp.395-400 Article dans une revue hal-00315220v1
	Inhibition of arginase in rat alveolar macrophages (AM phi) promotes utilization of L-arginine by nitric oxide synthase (NOS). C. Hey , Jl Boucher , S. Vadon , G. Ketterer , C. Stichnote Naunyn-Schmiedeberg's Archives of Pharmacology, 1997, 355, pp.138-138 Article dans une revue hal-00315242v1
	Oxidation of arylamidoximes by hydrogen peroxide and horseradish peroxidase in water: Easy preparation and X-ray structure of O-(arylimidoyl)arylamidoximes. Jl Boucher , S. Vadon , A. P. Tomas , B. Viossat , Xxxx Mansuyd Tetrahedron Letters, 1996, 37, pp.3113-3116 Article dans une revue hal-00315240v1
	Synthesis and effects on arginase and nitric oxide synthase of two novel analogues of N omega-hydroxyarginine, N omega-hydroxyindospicine and p-hydroxyamidinophenylalanine S. Vadon , J. Custot , Jl Boucher , Xxxx Mansuyd JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1996, xxx, pp.645-648 Article dans une revue hal-00315239v1
	Expression in yeast and purification of functional macrophage nitric oxide synthase. Evidence for cysteine-194 as iron proximal ligand. Ma Sari , S. Booker , M. Jaouen , S. Vadon , Ji Boucher Biochemistry, 1996, 35, pp.7204-7213 Article dans une revue hal-00315221v1
	N omega-hydroxyamino-alpha-amino acids as a new class of very strong inhibitors of arginases J. Custot , Jl Boucher , S. Vadon , C. Guedes , S. Dijols Journal of Biological Inorganic Chemistry, 1996, 1, pp.73-82 Article dans une revue hal-00315238v1
	N-OMEGA-HYDROXY-L-ARGININE, AN INTERMEDIATE IN THE L-ARGININE TO NITRIC-OXIDE PATHWAY, IS A STRONG INHIBITOR OF LIVER AND MACROPHAGE ARGINASE Jl Boucher , J. Custot , S. Vadon , M. Delaforge , M. Lepoivre Biochemical and Biophysical Research Communications, 1994, 203, pp.1614-1621 Article dans une revue hal-00315241v1
	N omega-hydroxyl-L-arginine, an intermediate in the L-arginine to nitric oxide pathway, is a strong inhibitor of liver and macrophage arginase. Jl Boucher , J. Custot , S. Vadon , M. Delaforge , M. Lepoivre Biochemical and Biophysical Research Communications, 1994, 203, pp.1614-1621 Article dans une revue hal-00315248v1
	Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s. Jp Renaud , Jl Boucher , S. Vadon , M. Delaforge , D. Mansuy Biochemical and Biophysical Research Communications, 1993, 192, pp.53-60 Article dans une revue hal-00315222v1
	Formation of nitrogen oxides and citrulline upon oxidation of N omega-hydroxy-L-arginine by hemeproteins. Jl Boucher , A. Genet , S. Vadon , M. Delaforge , D. Mansuy Biochemical and Biophysical Research Communications, 1992, 184, pp.1158-1164 Article dans une revue hal-00315224v1
	Cytochrome P450 catalyzes the oxidation of N omega-hydroxy-L-arginine by NADPH and O2 to nitric oxide and citrulline. Jl Boucher , A. Genet , S. Vadon , M. Delaforge , Y. Henry Biochemical and Biophysical Research Communications, 1992, 187, pp.880-886 Article dans une revue hal-00315223v1

	Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system Marine Blanc , Clara Lettl , Jérémy Guérin , Anaïs Vieille , Sven Furler 2022 Pré-publication, Document de travail hal-03850702v1
	Production of recombinant heterotrimeric mini-procollagen I and homotrimeric mini-procollagen II reveals new cleavage sites for BMP-1 Natacha Mariano , Cindy Dieryckx , Agnès Tessier , Jean-Baptiste Vincourt , Sandrine Vadon-Le Goff 2022 Pré-publication, Document de travail hal-03851708v1
	Procollagen C-Proteinase Enhancer 1 (PCPE-1) is a marker of myocardial fibrosis and impaired cardiac function in a murine model of pressure overload Priscillia Lagoutte , Alexandra Oudot , Mélissa Dussoyer , Victor Goncalves , Mélanie Guillemin 2021 Pré-publication, Document de travail hal-03372769v1

Sandrine Vadon - Le Goff

Publications

Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases

Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system

Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1)

Procollagen C-proteinase enhancer-1 (PCPE-1), a potential biomarker and therapeutic target for fibrosis

BMP-1 disrupts cell adhesion and enhances TGF-β activation through cleavage of the matricellular protein thrombospondin-1

Inhibitors of BMP-1/tolloid-like proteinases: efficacy, selectivity and cellular toxicity

Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1

Structural Basis for the Acceleration of Procollagen Processing by Procollagen C-Proteinase Enhancer-1

Interaction of Complement Defence Collagens C1q and Mannose-Binding Lectin with BMP-1/Tolloid-like Proteinases

Deficiency of the DSPP-cleaving enzymes meprin α and meprin β does not result in dentin malformation in mice

Structural basis of homo- and heterotrimerization of collagen I

Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-β signaling as primary targets

BMP-1/tolloid-like proteinases synchronize matrix assembly with growth factor activation to promote morphogenesis and tissue remodeling

Proteolytic control of TGF-β co-receptor activity by BMP-1/tolloid-like proteases revealed by quantitative iTRAQ proteomics

Procollagen C-proteinase enhancer grasps the stalk of the C-propeptide trimer to boost collagen precursor maturation.

IMPROVED AND HIGH YIELD SYNTHESIS OF THE POTENT ARGINASE INHIBITOR : 2(S)-AMINO-6-BORONOHEXANOIC ACID

SYNTHESIS AND EVALUATION OF NEW OMEGA-BORONO-ALPHA-AMINOACIDS AS RAT LIVER ARGINASE INHIBITORS

Coordination chemistry of the heme in cystathionine beta-synthase: formation of iron(II)-isonitrile complexes.

Modulation of cholinergic airway reactivity and nitric oxide production by endogenous arginase activity.

Biosynthèse du monoxyde d'azote (NO) : mécanisme, régulation et contrôle

N-omega-OH-D,L-indospicine, a potent and selective: Inhibitor of arginase in rat and rabbit alveolar macrophages (AM phi) can promote utilization of L-arginine by nitric oxide synthase (NOS)

Inhibition of arginase in rat and rabbit alveolar macrophages by N omega-hydroxy-D,L-indospicine, effects on L-arginine utilization by nitric oxide synthase.

Inhibition of arginase in rat alveolar macrophages (AM phi) promotes utilization of L-arginine by nitric oxide synthase (NOS).

Oxidation of arylamidoximes by hydrogen peroxide and horseradish peroxidase in water: Easy preparation and X-ray structure of O-(arylimidoyl)arylamidoximes.

Synthesis and effects on arginase and nitric oxide synthase of two novel analogues of N omega-hydroxyarginine, N omega-hydroxyindospicine and p-hydroxyamidinophenylalanine

Expression in yeast and purification of functional macrophage nitric oxide synthase. Evidence for cysteine-194 as iron proximal ligand.

N omega-hydroxyamino-alpha-amino acids as a new class of very strong inhibitors of arginases

N-OMEGA-HYDROXY-L-ARGININE, AN INTERMEDIATE IN THE L-ARGININE TO NITRIC-OXIDE PATHWAY, IS A STRONG INHIBITOR OF LIVER AND MACROPHAGE ARGINASE

N omega-hydroxyl-L-arginine, an intermediate in the L-arginine to nitric oxide pathway, is a strong inhibitor of liver and macrophage arginase.

Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s.

Formation of nitrogen oxides and citrulline upon oxidation of N omega-hydroxy-L-arginine by hemeproteins.

Cytochrome P450 catalyzes the oxidation of N omega-hydroxy-L-arginine by NADPH and O2 to nitric oxide and citrulline.

Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system

Production of recombinant heterotrimeric mini-procollagen I and homotrimeric mini-procollagen II reveals new cleavage sites for BMP-1

Procollagen C-Proteinase Enhancer 1 (PCPE-1) is a marker of myocardial fibrosis and impaired cardiac function in a murine model of pressure overload