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HPLC Analysis and Skin Whitening Effects of Umbelliprenin-containing Extracts of Anethum Graveolens, Pimpinella Anisum, and Ferulago Campestris

Vito Taddeo , Francesco Epifano , Francesca Preziuso , Serena Fiorito , Nicolas Caron , et al.
Molecules, 2019, 24 (3), pp.501. ⟨10.3390/molecules24030501⟩
Article dans une revue inserm-02380544v1
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Extracellular vesicles: lipids as key components of their biogenesis and functions

Michel Record , Sandrine Silvente-Poirot , Marc Poirot , Michael J. O. Wakelam
Journal of Lipid Research, 2018, 59 (8), pp.1316-1324. ⟨10.1194/jlr.E086173⟩
Article dans une revue inserm-02380557v1
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Improvement of 5,6α-epoxycholesterol, 5,6β-epoxycholesterol, cholestane-3β,5α,6β-triol and 6-oxo-cholestan-3β,5α-diol recovery for quantification by GC/MS

Régis Soules , Emmanuel Noguer , Luigi Iuliano , Chiara Zerbinati , Julie Leignadier , et al.
Chemistry and Physics of Lipids, 2017, 207, pp.92-98. ⟨10.1016/j.chemphyslip.2017.05.006⟩
Article dans une revue inserm-02380612v1

The novel steroidal alkaloids dendrogenin A and B promote proliferation of adult neural stem cells.

Shaden A. M. Khalifa , Philippe de Médina , Anna Erlandsson , Hesham R. El-Seedi , Sandrine Silvente-Poirot , et al.
Biochemical and Biophysical Research Communications, 2014, 446 (3), pp.681-6. ⟨10.1016/j.bbrc.2013.12.134⟩
Article dans une revue inserm-00968932v1

Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies.

Michel Record , Kevin Carayon , Marc Poirot , Sandrine Silvente-Poirot
BBA - Biochimica et Biophysica Acta, 2014, 1841 (1), pp.108-20. ⟨10.1016/j.bbalip.2013.10.004⟩
Article dans une revue inserm-00968935v1
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Quantitative analysis of the tumor suppressor dendrogenin A using liquid chromatography tandem mass spectrometry

Emmanuel Noguer , Régis Soules , Claude Netter , Citra Nagarathinam , Julie Leignadier , et al.
Chemistry and Physics of Lipids, 2017, 207, pp.81-86. ⟨10.1016/j.chemphyslip.2017.06.010⟩
Article dans une revue inserm-02380602v1

Chemical synthesis and biochemical properties of cholestane-5α,6β-diol-3-sulfonate: A non-hydrolysable analogue of cholestane-5α,6β-diol-3β-sulfate

Philippe de Medina , Silia Ayadi , Régis Soulès , Bruno Payre , Sandrine Rup-Jacques , et al.
Journal of Steroid Biochemistry and Molecular Biology, 2023, 234, pp.106396. ⟨10.1016/j.jsbmb.2023.106396⟩
Article dans une revue hal-04509731v1

The Cholesterol-5,6-Epoxide Hydrolase: A Metabolic Checkpoint in Several Diseases

Philippe de Medina , Silia Ayadi , Khadijetou Diallo , Julio Buñay , Laly Pucheu , et al.
Implication of Oxysterols and Phytosterols in Aging and Human Diseases, 1440, Springer International Publishing, pp.149-161, 2024, Advances in Experimental Medicine and Biology, ⟨10.1007/978-3-031-43883-7_8⟩
Chapitre d'ouvrage inserm-04317348v1
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Molecular and Biochemical Analysis of the Estrogenic and Proliferative Properties of Vitamin E Compounds

Farid Khallouki , Philippe de Médina , Stéphanie Caze-Subra , Kerstin Bystricky , Patrick Balaguer , et al.
Frontiers in Oncology, 2016, 5, ⟨10.3389/fonc.2015.00287⟩
Article dans une revue hal-02271824v1

Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophiles.

Michael R. Paillasse , Nathalie Saffon , Heinz Gornitzka , Sandrine Silvente-Poirot , Marc Poirot , et al.
Journal of Lipid Research, 2012, 53 (4), pp.718-25. ⟨10.1194/jlr.M023689⟩
Article dans une revue inserm-00743457v1
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Circulating oxysterol metabolites as potential new surrogate markers in patients with hormone receptor-positive breast cancer: Results of the OXYTAM study

Florence Dalenc , Luiggi Iuliano , Thomas Filleron , Chiara Zerbinati , Maud Voisin , et al.
Journal of Steroid Biochemistry and Molecular Biology, 2017, 169, pp.210-218. ⟨10.1016/j.jsbmb.2016.06.010⟩
Article dans une revue inserm-02380620v1
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Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia

Pierre-Luc Mouchel , Nizar Serhan , Rémy Bétous , Thomas Farge , Estelle Saland , et al.
Cancers, 2020, 12 (10), pp.2933. ⟨10.3390/cancers12102933⟩
Article dans une revue inserm-03084630v1
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The tumor-suppressor cholesterol metabolite, dendrogenin A, is a new class of LXR modulator activating lethal autophagy in cancers

Sandrine Silvente-Poirot , Marc Poirot
Biochemical Pharmacology, 2018, 153, pp.75-81. ⟨10.1016/j.bcp.2018.01.046⟩
Article dans une revue inserm-02380575v1

Vitamin E: an overview

Farid Khallouki , Robert Wyn Owen , Mourad Akdad , Bachir El Bouhali , Sandrine Silvente-Poirot , et al.
Molecular Nutrition, Elsevier, pp.51-66, 2020, ⟨10.1016/B978-0-12-811907-5.00001-4⟩
Chapitre d'ouvrage inserm-03084874v1

Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion.

Michael R. Paillasse , Philippe de Médina , Guillaume Amouroux , Loubna Mhamdi , Marc E. Poirot , et al.
Journal of Lipid Research, 2009, 50 (11), pp.2203-11. ⟨10.1194/jlr.M800668-JLR200⟩
Article dans une revue inserm-00519146v1

Insights into the cholecystokinin 2 receptor binding site and processes of activation.

Michaël Paillasse , Céline Deraeve , Philippe de Médina , Loubna Mhamdi , Gilles Favre , et al.
Molecular Pharmacology, 2006, 70 (6), pp.1935-45. ⟨10.1124/mol.106.029967⟩
Article dans une revue inserm-00519168v1

Molecular characterization of the microsomal tamoxifen binding site.

Blandine Kedjouar , Philippe de Médina , Mustapha Oulad-Abdelghani , Bruno Payré , Sandrine Silvente-Poirot , et al.
Journal of Biological Chemistry, 2004, 279, pp.34048-61. ⟨10.1074/jbc.M405230200⟩
Article dans une revue inserm-00090773v1

27-hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor

Silia Ayadi , Silvia Friedrichs , Regis Soulès , Laly Pucheu , Dieter Lütjohann , et al.
Journal of Lipid Research, In press, 64 (12), pp.100479. ⟨10.1016/j.jlr.2023.100479⟩
Article dans une revue inserm-04317313v1
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Is cholesterol a risk factor for breast cancer incidence and outcome?

Céline Ben Hassen , Caroline Goupille , Claire Vigor , Thierry Durand , Françoise Guéraud , et al.
Journal of Steroid Biochemistry and Molecular Biology, In press, pp.106346. ⟨10.1016/j.jsbmb.2023.106346⟩
Article dans une revue hal-04165228v1

Cancer. Cholesterol and cancer, in the balance.

Sandrine Silvente-Poirot , Marc Poirot
Science, 2014, 343 (6178), pp.1445-6. ⟨10.1126/science.1252787⟩
Article dans une revue inserm-00968924v1

Ligands of the antiestrogen-binding site induce active cell death and autophagy in human breast cancer cells through the modulation of cholesterol metabolism.

Philippe de Médina , Bruno Payré , Nadia Boubekeur , Justine Bertrand-Michel , François Tercé , et al.
Cell Death and Differentiation, 2009, 16 (10), pp.1372-84. ⟨10.1038/cdd.2009.62⟩
Article dans une revue inserm-00519149v1

Technical note: Hapten synthesis, antibody production and development of an enzyme-linked immunosorbent assay for detection of the natural steroidal alkaloid Dendrogenin A.

Philippe de Médina , Michael R. Paillasse , Gregory Segala , Talal Al Saati , Jeannine Boyes , et al.
Biochimie, 2013, 95 (3), pp.482-8. ⟨10.1016/j.biochi.2012.06.001⟩
Article dans une revue istex inserm-00822283v1

Development of a new radioligand for cholecystokinin receptor subtype 2 scintigraphy: from molecular modeling to in vivo evaluation.

Séverine Brillouet , Sandra Dorbes , Frédéric Courbon , Claude Picard , Jean Pierre Delord , et al.
Bioorganic and Medicinal Chemistry, 2010, 18 (14), pp.5400-12. ⟨10.1016/j.bmc.2010.05.031⟩
Article dans une revue istex inserm-00519158v1

met-195 of the cholecystokinin-A receptor interacts with the sulfated tyrosine of cholecystokinin and is crucial for receptor transition to high affinity state

Véronique Gigoux , Chantal Escrieu , Sandrine Silvente-Poirot , Bernard Maigret , Laurent Goullieux , et al.
Journal of Biological Chemistry, 1998, 273 (23), pp.14380-14386
Article dans une revue hal-00357491v1

arginine 197 of the cholecystokinin a receptor binding site interacts with the sulfate of the peptide agonist cholecystokinin

Véronique Gigoux , Bernard Maigret , Chantal Escrieu , Sandrine Silvente-Poirot , Michelle Buisson , et al.
Protein Science, 1999, 11, pp.2347-2354
Article dans une revue hal-00357556v1

Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism.

Bruno Payré , Philippe de Médina , Nadia Boubekeur , Loubna Mhamdi , Justine Bertrand-Michel , et al.
Molecular Cancer Therapeutics, 2008, 7 (12), pp.3707-18. ⟨10.1158/1535-7163.MCT-08-0507⟩
Article dans une revue inserm-00519145v1

Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor

Maud Voisin , Philippe de Médina , Arnaud Mallinger , Florence Dalenc , Emilie Huc-Claustre , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (44), pp.E9346-E9355. ⟨10.1073/pnas.1707965114⟩
Article dans une revue hal-02316171v1
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Targeting the liver X receptor with dendrogenin A differentiates tumour cells to secrete immunogenic exosome‐enriched vesicles

Michel Record , Mehdi Attia , Kevin Carayon , Laly Pucheu , Julio Bunay , et al.
Journal of Extracellular Vesicles, 2022, 11 (4), pp.e12211. ⟨10.1002/jev2.12211⟩
Article dans une revue inserm-03649213v1

Targeting NR1H/liver X receptor with dendrogenin A differentiates tumor cells to activate a new secretory pathway releasing immunogenic anti-tumor vesicles enriched in LC3-II-associated exosomes

Philippe de Medina , Julio Bunay , Marc Poirot , Michel Record , Sandrine Silvente-Poirot
Autophagy, 2022, pp.1-3. ⟨10.1080/15548627.2022.2116175⟩
Article dans une revue inserm-03854248v1

One step synthesis of 6-oxo-cholestan-3β,5α-diol.

Maud Voisin , Sandrine Silvente-Poirot , Marc Poirot
Biochemical and Biophysical Research Communications, 2014, epub ahead of print. ⟨10.1016/j.bbrc.2014.01.138⟩
Article dans une revue inserm-00968933v1